Works by Ya-Chea Tsai

Results: 16

Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity.

Published in:

Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00841-y

By:

Kung, Yu-Jui;
Lam, Brandon;
Tseng, Ssu-Hsueh;
MacDonald, Alana;
Tu, Hsin-Fang;
Wang, Suyang;
Lin, John;
Tsai, Ya Chea;
Wu, T. C.;
Hung, Chien-Fu

Publication type:

Article

A novel pseudovirus‐based mouse model of SARS-CoV-2 infection to test COVID-19 interventions.

Published in:

Journal of Biomedical Science, 2021, v. 28, n. 1, p. 1, doi. 10.1186/s12929-021-00729-3

By:

Tseng, Ssu-Hsueh;
Lam, Brandon;
Kung, Yu Jui;
Lin, John;
Liu, Li;
Tsai, Ya Chea;
Ferrall, Louise;
Roden, Richard B. S.;
Wu, T. C.;
Hung, Chien-Fu

Publication type:

Article

Type I Interferon Modulates the Function of Ly6C High-Expressing Naïve CD8 + T Cells to Promote an Antitumor Response.

Published in:

Vaccines, 2025, v. 13, n. 3, p. 246, doi. 10.3390/vaccines13030246

By:

Tu, Hsin-Fang;
Tao, Julia;
Hu, Ming-Hung;
Fan, Darrell;
Tsai, Ya-Chea;
Wu, Tzyy-Choou;
Hung, Chien-Fu

Publication type:

Article

STAT1-Deficient HPV E6/E7-Associated Cancers Maintain Host Immunocompetency against Therapeutic Intervention.

Published in:

Vaccines, 2024, v. 12, n. 4, p. 430, doi. 10.3390/vaccines12040430

By:

Lim, Ling;
Hu, Ming-Hung;
Fan, Darrell;
Tu, Hsin-Fang;
Tsai, Ya-Chea;
Cheng, Michelle;
Wang, Suyang;
Chang, Chih-Long;
Wu, Tzyy-Choou;
Hung, Chien-Fu

Publication type:

Article

Salmonella immunotherapy engineered with highly efficient tumor antigen coating establishes antigen-specific CD8+ T cell immunity and increases in antitumor efficacy with type I interferon combination therapy.

Published in:

OncoImmunology, 2024, v. 13, n. 1, p. 1, doi. 10.1080/2162402X.2023.2298444

By:

Wang, Suyang;
Cheng, Michelle;
Chen, Chao-Cheng;
Chang, Chia-Yu;
Tsai, Ya-Chea;
Yang, Jr-Ming;
Wu, TC;
Huang, Chuan-Hsiang;
Hung, Chien-Fu

Publication type:

Article

Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice.

Published in:

Journal of Biomedical Science, 2022, v. 29, n. 1, p. 1, doi. 10.1186/s12929-022-00864-5

By:

Peng, Shiwen;
Xing, Deyin;
Ferrall, Louise;
Tsai, Ya-Chea;
Hung, Chien-Fu;
Wu, T.-C.

Publication type:

Article

A DNA Vaccine Encoding a Codon-Optimized Human Papillomavirus Type 16 E6 Gene Enhances CTL Response and Anti-tumor Activity.

Published in:

Journal of Biomedical Science, 2006, v. 13, n. 4, p. 481, doi. 10.1007/s11373-006-9086-6

By:

Cheng-Tao Lin;
Ya-Chea Tsai;
Liangmei He;
Calizo, Roanne;
Hung-Hsueh Chou;
Ting-Chang Chang;
Yung-Kuei Soong;
Chien-Fu Hung;
Chyong-Huey Lai

Publication type:

Article

Characterization of HPV-16 E6 DNA vaccines employing intracellular targeting and intercellular spreading strategies.

Published in:

Journal of Biomedical Science, 2005, v. 12, n. 5, p. 689, doi. 10.1007/s11373-005-9012-3

By:

Shiwen Peng;
Trimble, Cornelia;
Hongxiu Ji;
Liangmei He;
Ya-Chea Tsai;
Macaes, Bruno;
Chien-Fu Hung;
Wu, T.-C.

Publication type:

Article

Enhancing the Therapeutic Effect Against Ovarian Cancer Through a Combination of Viral Oncolysis and Antigen-specific Immunotherapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 4, p. 692, doi. 10.1038/mt.2009.318

By:

Yu-Qian Zhang;
Ya-Chea Tsai;
Monie, Archana;
Wu, T.-C.;
Chien-Fu Hung

Publication type:

Article

DNA Vaccines Encoding Ii-PADRE Generates Potent PADRE-specific CD4<sup>+</sup> T-Cell Immune Responses and Enhances Vaccine Potency.

Published in:

Molecular Therapy, 2007, v. 15, n. 6, p. 1211, doi. 10.1038/sj.mt.6300121

By:

Chien-Fu Hung;
Ya-Chea Tsai;
Liangmei He;
Wu, T.-C.

Publication type:

Article

Generation of a spontaneous murine HPV + oral cancer model with site-specific oncogene insertion using CRISPR-SONIC.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01427-5

By:

Tao, Julia;
Murray, Jason;
Tu, Hsin-Fang;
Fan, Darrell;
Tsai, Ya-Chea;
Hu, Ming-Hung;
Wu, Annie A.;
Xing, Deyin;
Hung, Chien-Fu;
Wu, T.-C.

Publication type:

Article

Delivery of IL-2 to the T Cell Surface Through Phosphatidylserine Permits Robust Expansion of CD8 T Cells.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.755995

By:

MacDonald, Alana;
Lam, Brandon;
Lin, John;
Ferrall, Louise;
Kung, Yu Jui;
Tsai, Ya Chea;
Wu, T.-C.;
Hung, Chien-Fu

Publication type:

Article

Direct T Cell Activation via CD40 Ligand Generates High Avidity CD8<sup>+</sup> T Cells Capable of Breaking Immunological Tolerance for the Control of Tumors.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0093162

By:

Soong, Ruey-Shyang;
Song, Liwen;
Trieu, Janson;
Lee, Sung Yong;
He, Liangmei;
Tsai, Ya-Chea;
Wu, T.-C.;
Hung, Chien-Fu

Publication type:

Article

Xenogeneic Human p53 DNA Vaccination by Electroporation Breaks Immune Tolerance to Control Murine Tumors Expressing Mouse p53.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056912

By:

Soong, Ruey-Shyang;
Trieu, Janson;
Lee, Sung Yong;
He, Liangmei;
Tsai, Ya-Chea;
Wu, T.-C.;
Hung, Chien-Fu

Publication type:

Article

Tumor-Targeted Delivery of IL-2 by NKG2D Leads to Accumulation of Antigen-Specific CD8+ T Cells in the Tumor Loci and Enhanced Anti-Tumor Effects.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035141

By:

Tae Heung Kang;
Chih-Ping Mao;
Liangmei He;
Ya-Chea Tsai;
Katherine Liu;
Victor La;
T.-C. Wu;
Chien-Fu Hung

Publication type:

Article

Buccal injection of synthetic HPV long peptide vaccine induces local and systemic antigen.specific CD8+ T.cell immune responses and antitumor effects without adjuvant.

Published in:

Cell & Bioscience, 2016, p. 1, doi. 10.1186/s13578-016-0083-9

By:

Ming-Chieh Yang;
Yang, Andrew;
Jin Qiu;
Benjamin Yang;
Liangmei He;
Ya-Chea Tsai;
Jeang, Jessica;
Wu, T. -C.;
Chien-Fu Hung

Publication type:

Article