Works by Varjosalo, Markku

Results: 84

Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis.

Published in:

FEBS Letters, 2025, v. 599, n. 9, p. 1299, doi. 10.1002/1873-3468.70001

By:

Nagaraj, Meghana;
Emmagouni, Sharath Kumar Goud;
Chaurasiya, Vaishali;
Li, Luyang;
Nguyen, Van Dien;
Keskitalo, Salla;
Varjosalo, Markku;
Zhou, You;
Haridas, P. A. Nidhina;
Olkkonen, Vesa M.

Publication type:

Article

ROR1-STAT3 signaling contributes to ovarian cancer intra-tumor heterogeneity.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01527-6

By:

Piki, Emilia;
Dini, Alice;
Raivola, Juuli;
Salokas, Kari;
Zhang, Kaiyang;
Varjosalo, Markku;
Pellinen, Teijo;
Välimäki, Katja;
Veskimäe, Kristina Tabor;
Staff, Synnöve;
Hautaniemi, Sampsa;
Murumägi, Astrid;
Ungureanu, Daniela

Publication type:

Article

Systems pathology analysis identifies neurodegenerative nature of age‐related vitreoretinal interface diseases.

Published in:

Aging Cell, 2018, v. 17, n. 5, p. 1, doi. 10.1111/acel.12809

By:

Öhman, Tiina;
Tamene, Fitsum;
Göös, Helka;
Loukovaara, Sirpa;
Varjosalo, Markku

Publication type:

Article

GATA-targeted compounds modulate cardiac subtype cell differentiation in dual reporter stem cell line.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-021-02259-z

By:

Välimäki, Mika J.;
Leigh, Robert S.;
Kinnunen, Sini M.;
March, Alexander R.;
de Sande, Ana Hernández;
Kinnunen, Matias;
Varjosalo, Markku;
Heinäniemi, Merja;
Kaynak, Bogac L.;
Ruskoaho, Heikki

Publication type:

Article

The Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations.

Published in:

Cancers, 2023, v. 15, n. 17, p. 4246, doi. 10.3390/cancers15174246

By:

Kinnunen, Matias;
Liu, Xiaonan;
Niemelä, Elina;
Öhman, Tiina;
Gawriyski, Lisa;
Salokas, Kari;
Keskitalo, Salla;
Varjosalo, Markku

Publication type:

Article

Decoding Oncofusions: Unveiling Mechanisms, Clinical Impact, and Prospects for Personalized Cancer Therapies.

Published in:

Cancers, 2023, v. 15, n. 14, p. 3678, doi. 10.3390/cancers15143678

By:

Salokas, Kari;
Dashi, Giovanna;
Varjosalo, Markku

Publication type:

Article

Deep Immune Profiling of Multiple Myeloma at Diagnosis and under Lenalidomide Maintenance Therapy.

Published in:

Cancers, 2023, v. 15, n. 9, p. 2604, doi. 10.3390/cancers15092604

By:

Luoma, Sini;
Sergeev, Philipp;
Javarappa, Komal Kumar;
Öhman, Tiina J.;
Varjosalo, Markku;
Säily, Marjaana;
Anttila, Pekka;
Sankelo, Marja;
Partanen, Anu;
Nihtinen, Anne;
Heckman, Caroline A.;
Silvennoinen, Raija

Publication type:

Article

Defining Optimal Conditions for Tumor Extracellular Vesicle DNA Extraction for Mutation Profiling.

Published in:

Cancers, 2022, v. 14, n. 13, p. N.PAG, doi. 10.3390/cancers14133258

By:

Elzanowska, Julia;
Berrocal, Laura;
García-Peláez, Beatriz;
Vives-Usano, Marta;
Sebo, Beatriz Passos;
Maia, Joana;
Batista, Silvia;
Teppo, Jaakko;
Varjosalo, Markku;
Moraes, Maria Carolina Strano;
Molina-Vila, Miguel Ángel;
Costa-Silva, Bruno

Publication type:

Article

Combined proximity labeling and affinity purification−mass spectrometry workflow for mapping and visualizing protein interaction networks.

Published in:

Nature Protocols, 2020, v. 15, n. 10, p. 3182, doi. 10.1038/s41596-020-0365-x

By:

Liu, Xiaonan;
Salokas, Kari;
Weldatsadik, Rigbe G.;
Gawriyski, Lisa;
Varjosalo, Markku

Publication type:

Article

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.

Published in:

EMBO Journal, 2010, v. 29, n. 13, p. 2147, doi. 10.1038/emboj.2010.106

By:

Gong-Hong Wei;
Badis, Gwenael;
Berger, Michael F.;
Kivioja, Teemu;
Palin, Kimmo;
Enge, Martin;
Bonke, Martin;
Jolma, Arttu;
Varjosalo, Markku;
Gehrke, Andrew R.;
Jian Yan;
Talukder, Shaheynoor;
Turunen, Mikko;
Taipale, Mikko;
Stunnenberg, Hendrik G.;
Ukkonen, Esko;
Hughes, Timothy R.;
Bulyk, Martha L.;
Taipale, Jussi

Publication type:

Article

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery.

Published in:

Molecular Systems Biology, 2021, v. 17, n. 11, p. 1, doi. 10.15252/msb.202110396

By:

Liu, Xiaonan;
Huuskonen, Sini;
Laitinen, Tuomo;
Redchuk, Taras;
Bogacheva, Mariia;
Salokas, Kari;
Pöhner, Ina;
Öhman, Tiina;
Tonduru, Arun Kumar;
Hassinen, Antti;
Gawriyski, Lisa;
Keskitalo, Salla;
Vartiainen, Maria K;
Pietiäinen, Vilja;
Poso, Antti;
Varjosalo, Markku

Publication type:

Article

Interaction proteome of human Hippo signaling: modular control of the co‐activator YAP1.

Published in:

Molecular Systems Biology, 2013, v. 9, n. 1, p. 1, doi. 10.1002/msb.201304750

By:

Hauri, Simon;
Wepf, Alexander;
van Drogen, Audrey;
Varjosalo, Markku;
Tapon, Nic;
Aebersold, Ruedi;
Gstaiger, Matthias

Publication type:

Article

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins.

Published in:

PLoS Pathogens, 2022, v. 18, n. 4, p. 1, doi. 10.1371/journal.ppat.1010353

By:

Mattola, Salla;
Salokas, Kari;
Aho, Vesa;
Mäntylä, Elina;
Salminen, Sami;
Hakanen, Satu;
Niskanen, Einari A.;
Svirskaite, Julija;
Ihalainen, Teemu O.;
Airenne, Kari J.;
Kaikkonen-Määttä, Minna;
Parrish, Colin R.;
Varjosalo, Markku;
Vihinen-Ranta, Maija

Publication type:

Article

Rapid genome editing by CRISPR-Cas9-POLD3 fusion.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75415

By:

Reint, Ganna;
Zhuokun Li;
Labun, Kornel;
Keskitalo, Salla;
Soppa, Inkeri;
Mamia, Katariina;
Tolo, Eero;
Szymanska, Monika;
Meza-Zepeda, Leonardo A.;
Lorenz, Susanne;
Cieslar-Pobuda, Artur;
Xian Hu;
Bordin, Diana L.;
Staerk, Judith;
Valen, Eivind;
Schmierer, Bernhard;
Varjosalo, Markku;
Taipale, Jussi;
Haapaniemi, Emma

Publication type:

Article

Rapid genome editing by CRISPR-Cas9-POLD3 fusion.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75415

By:

Reint, Ganna;
Zhuokun Li;
Labun, Kornel;
Keskitalo, Salla;
Soppa, Inkeri;
Mamia, Katariina;
Tolo, Eero;
Szymanska, Monika;
Meza Zepeda, Leonardo A.;
Lorenz, Susanne;
Pobuda, Artur Cieslar;
Xian Hu;
Bordin, Diana L.;
Staerk, Judith;
Valen, Eivind;
Schmierer, Bernhard;
Varjosalo, Markku;
Taipale, Jussi;
Haapaniemi, Emma

Publication type:

Article

Molecular pathogenesis of rhegmatogenous retinal detachment.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80005-w

By:

Öhman, Tiina;
Gawriyski, Lisa;
Miettinen, Sini;
Varjosalo, Markku;
Loukovaara, Sirpa

Publication type:

Article

Human transcription factor and protein kinase gene fusions in human cancer.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71040-8

By:

Salokas, Kari;
Weldatsadik, Rigbe G.;
Varjosalo, Markku

Publication type:

Article

Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.819929

By:

Pernaa, Nora;
Keskitalo, Salla;
Chowdhury, Iftekhar;
Nissinen, Antti;
Glumoff, Virpi;
Keski-Filppula, Riikka;
Junttila, Juhani;
Eklund, Kari K.;
Santaniemi, Wenny;
Siitonen, Sanna;
Seppänen, Mikko R. J.;
Vähäsalo, Paula;
Varjosalo, Markku;
Åström, Pirjo;
Hautala, Timo

Publication type:

Article

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03523-2

By:

Xiaonan Liu;
Salokas, Kari;
Tamene, Fitsum;
Yaming Jiu;
Weldatsadik, Rigbe G.;
Öhman, Tiina;
Varjosalo, Markku

Publication type:

Article

Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention.

Published in:

Cell Death & Disease, 2022, v. 13, n. 8, p. 1, doi. 10.1038/s41419-022-05161-5

By:

Raivola, Juuli;
Dini, Alice;
Karvonen, Hanna;
Piki, Emilia;
Salokas, Kari;
Niininen, Wilhelmiina;
Kaleva, Laura;
Zhang, Kaiyang;
Arjama, Mariliina;
Gudoityte, Greta;
Seashore-Ludlow, Brinton;
Varjosalo, Markku;
Kallioniemi, Olli;
Hautaniemi, Sampsa;
Murumägi, Astrid;
Ungureanu, Daniela

Publication type:

Article

Single-cell omics techniques to elucidate cell-to-cell variability in signalling cascades involved in human diseases.

Published in:

2023

By:

Keskitalo, Salla;
Varjosalo, Markku

Publication type:

Editorial

Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication.

Published in:

PLoS Pathogens, 2016, v. 12, n. 2, p. 1, doi. 10.1371/journal.ppat.1005424

By:

Balistreri, Giuseppe;
Viiliäinen, Johanna;
Turunen, Mikko;
Diaz, Raquel;
Lyly, Lauri;
Pekkonen, Pirita;
Rantala, Juha;
Ojala, Krista;
Sarek, Grzegorz;
Teesalu, Mari;
Denisova, Oxana;
Peltonen, Karita;
Julkunen, Ilkka;
Varjosalo, Markku;
Kainov, Denis;
Kallioniemi, Olli;
Laiho, Marikki;
Taipale, Jussi;
Hautaniemi, Sampsa;
Ojala, Päivi M.

Publication type:

Article

A proteomics view on integrin-mediated adhesions.

Published in:

Proteomics, 2017, v. 17, n. 3/4, p. n/a, doi. 10.1002/pmic.201600022

By:

Manninen, Aki;
Varjosalo, Markku

Publication type:

Article

Reduced binding of apoE4 to complement factor H promotes amyloid‐β oligomerization and neuroinflammation.

Published in:

EMBO Reports, 2023, v. 24, n. 7, p. 1, doi. 10.15252/embr.202256467

By:

Chernyaeva, Larisa;
Ratti, Giorgio;
Teirilä, Laura;
Fudo, Satoshi;
Rankka, Uni;
Pelkonen, Anssi;
Korhonen, Paula;
Leskinen, Katarzyna;
Keskitalo, Salla;
Salokas, Kari;
Gkolfinopoulou, Christina;
Crompton, Katrina E;
Javanainen, Matti;
Happonen, Lotta;
Varjosalo, Markku;
Malm, Tarja;
Leinonen, Ville;
Chroni, Angeliki;
Saavalainen, Päivi;
Meri, Seppo

Publication type:

Article

Physical and functional interactome atlas of human receptor tyrosine kinases.

Published in:

EMBO Reports, 2022, v. 23, n. 6, p. 1, doi. 10.15252/embr.202154041

By:

Salokas, Kari;
Liu, Xiaonan;
Öhman, Tiina;
Chowdhury, Iftekhar;
Gawriyski, Lisa;
Keskitalo, Salla;
Varjosalo, Markku

Publication type:

Article

Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival.

Published in:

EMBO Reports, 2019, v. 20, n. 1, p. N.PAG, doi. 10.15252/embr.201846557

By:

Cortes, Ernesto;
Lachowski, Dariusz;
Robinson, Benjamin;
Sarper, Muge;
Teppo, Jaakko S;
Thorpe, Stephen D;
Lieberthal, Tyler J;
Iwamoto, Kazunari;
Lee, David A;
Okada‐Hatakeyama, Mariko;
Varjosalo, Markku T;
Río Hernández, Armando E

Publication type:

Article

Novel TMEM173 Mutation and the Role of Disease Modifying Alleles.

Published in:

Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02770

By:

Keskitalo, Salla;
Haapaniemi, Emma;
Einarsdottir, Elisabet;
Rajamäki, Kristiina;
Heikkilä, Hannele;
Ilander, Mette;
Pöyhönen, Minna;
Morgunova, Ekaterina;
Hokynar, Kati;
Lagström, Sonja;
Kivirikko, Sirpa;
Mustjoki, Satu;
Eklund, Kari;
Saarela, Janna;
Kere, Juha;
Seppänen, Mikko R. J.;
Ranki, Annamari;
Hannula-Jouppi, Katariina;
Varjosalo, Markku

Publication type:

Article

Biallelic mutations in human NHLRC2 enhance myofibroblast differentiation in FINCA disease.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 24, p. 4288, doi. 10.1093/hmg/ddy298

By:

Paakkola, Teija;
Salokas, Kari;
Miinalainen, Ilkka;
Lehtonen, Siri;
Manninen, Aki;
Kaakinen, Mika;
Ruddock, Lloyd W;
Varjosalo, Markku;
Kaarteenaho, Riitta;
Uusimaa, Johanna

Publication type:

Article

P-067: High dimensional CyTOF analysis of the immune system of multiple myeloma patients with different responses to lenalidomide maintenance.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S75, doi. 10.1016/S2152-2650(21)02201-1

By:

Silvennoinen, Raija;
Javarappa, Komal Kumar;
Luoma, Sini;
Sergeev, Philipp;
Anttila, Pekka;
Öhman, Tiina;
Varjosalo, Markku;
Säily, Marjaana;
Partanen, Anu;
sankelo, Marja;
Heckman, Caroline

Publication type:

Article

Behçet disease (BD) and BD‐like clinical phenotypes: NF‐κB pathway in mucosal ulcerating diseases.

Published in:

Scandinavian Journal of Immunology, 2020, v. 92, n. 5, p. 1, doi. 10.1111/sji.12973

By:

Perazzio, Sandro F.;
Allenspach, Eric J.;
Eklund, Kari K.;
Varjosalo, Markku;
Shinohara, Michi M.;
Torgerson, Troy R.;
Seppänen, Mikko R. J.

Publication type:

Article

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 6, p. 1748, doi. 10.1210/clinem/dgaa078

By:

Hietamäki, Johanna;
Gregory, Louise C.;
Ayoub, Sandy;
Iivonen, Anna-Pauliina;
Vaaralahti, Kirsi;
Xiaonan Liu;
Brandstack, Nina;
Buckton, Andrew J.;
Laine, Tiina;
Känsäkoski, Johanna;
Hero, Matti;
Miettinen, Päivi J.;
Varjosalo, Markku;
Wakeling, Emma;
Dattani, Mehul T.;
Raivio, Taneli

Publication type:

Article

Nuclear proteome of virus-infected and healthy potato leaves.

Published in:

BMC Plant Biology, 2020, v. 20, n. 1, p. 1, doi. 10.1186/s12870-020-02561-7

By:

Rajamäki, Minna-Liisa;
Sikorskaite-Gudziuniene, Sidona;
Sarmah, Nandita;
Varjosalo, Markku;
Valkonen, Jari P. T.

Publication type:

Article

Association of host protein VARICOSE with HCPro within a multiprotein complex is crucial for RNA silencing suppression, translation, encapsidation and systemic spread of potato virus A infection.

Published in:

PLoS Pathogens, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.ppat.1008956

By:

De, Swarnalok;
Pollari, Maija;
Varjosalo, Markku;
Mäkinen, Kristiina

Publication type:

Article

Interaction network of human early embryonic transcription factors.

Published in:

EMBO Reports, 2024, v. 25, n. 3, p. 1589, doi. 10.1038/s44319-024-00074-0

By:

Gawriyski, Lisa;
Tan, Zenglai;
Liu, Xiaonan;
Chowdhury, Iftekhar;
Malaymar Pinar, Dicle;
Zhang, Qin;
Weltner, Jere;
Jouhilahti, Eeva-Mari;
Wei, Gong-Hong;
Kere, Juha;
Varjosalo, Markku

Publication type:

Article

Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O:3 are mediated by derepression of the transcriptional regulator RovM.

Published in:

Molecular Microbiology, 2017, v. 103, n. 6, p. 1065, doi. 10.1111/mmi.13610

By:

Leskinen, Katarzyna;
Pajunen, Maria I.;
Varjosalo, Markku;
Fernández‐Carrasco, Helena;
Bengoechea, José A.;
Skurnik, Mikael

Publication type:

Article

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism.

Published in:

2020

By:

Hietamäki, Johanna;
Gregory, Louise C;
Ayoub, Sandy;
Iivonen, Anna-Pauliina;
Vaaralahti, Kirsi;
Liu, Xiaonan;
Brandstack, Nina;
Buckton, Andrew J;
Laine, Tiina;
Känsäkoski, Johanna;
Hero, Matti;
Miettinen, Päivi J;
Varjosalo, Markku;
Wakeling, Emma;
Dattani, Mehul T;
Raivio, Taneli

Publication type:

journal article

Functional omics of ORP7 in primary endothelial cells.

Published in:

BMC Biology, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12915-024-02087-6

By:

Taskinen, Juuso H.;
Holopainen, Minna;
Ruhanen, Hanna;
van der Stoel, Miesje;
Käkelä, Reijo;
Ikonen, Elina;
Keskitalo, Salla;
Varjosalo, Markku;
Olkkonen, Vesa M.

Publication type:

Article

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils.

Published in:

Biological Procedures Online, 2020, v. 22, n. 1, p. 1, doi. 10.1186/s12575-020-00118-4

By:

Aaltonen, Niina;
Singha, Prosanta K.;
Jakupović, Hermina;
Wirth, Thomas;
Samaranayake, Haritha;
Pasonen-Seppänen, Sanna;
Rilla, Kirsi;
Varjosalo, Markku;
Edgington-Mitchell, Laura E.;
Kasperkiewicz, Paulina;
Drag, Marcin;
Kälvälä, Sara;
Moisio, Eemeli;
Savinainen, Juha R.;
Laitinen, Jarmo T.

Publication type:

Article

Whole-exome sequencing reveals candidate high-risk susceptibility genes for endometriosis.

Published in:

Human Genomics, 2023, v. 17, n. 1, p. 1, doi. 10.1186/s40246-023-00538-9

By:

Nousiainen, Susanna;
Kuismin, Outi;
Reinikka, Siiri;
Manninen, Roosa;
Khamaiseh, Sara;
Kuivalainen, Mari;
Terho, Anna;
Koivurova, Sari;
Niinimäki, Maarit;
Salokas, Kari;
Varjosalo, Markku;
Ahtikoski, Anne;
Bützow, Ralf;
Lindgren, Outi;
Uimari, Outi;
Vahteristo, Pia

Publication type:

Article

Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.

Published in:

Human Mutation, 2017, v. 38, n. 3, p. 269, doi. 10.1002/humu.23157

By:

Heikkinen, Tuomas;
Kämpjärvi, Kati;
Keskitalo, Salla;
von Nandelstadh, Pernilla;
Liu, Xiaonan;
Rantanen, Ville;
Pitkänen, Esa;
Kinnunen, Matias;
Kuusanmäki, Heikki;
Kontro, Mika;
Turunen, Mikko;
Mäkinen, Netta;
Taipale, Jussi;
Heckman, Caroline;
Lehti, Kaisa;
Mustjoki, Satu;
Varjosalo, Markku;
Vahteristo, Pia

Publication type:

Article

The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50334-6

By:

Vakkilainen, Svetlana;
Skoog, Tiina;
Einarsdottir, Elisabet;
Middleton, Anna;
Pekkinen, Minna;
Öhman, Tiina;
Katayama, Shintaro;
Krjutškov, Kaarel;
Kovanen, Panu E.;
Varjosalo, Markku;
Lindqvist, Arne;
Kere, Juha;
Mäkitie, Outi

Publication type:

Article

New insights into the molecular mechanisms of ROR1, ROR2, and PTK7 signaling from the proteomics and pharmacological modulation of ROR1 interactome.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 5, p. 1, doi. 10.1007/s00018-022-04301-6

By:

Raivola, Juuli;
Dini, Alice;
Salokas, Kari;
Karvonen, Hanna;
Niininen, Wilhelmiina;
Piki, Emilia;
Varjosalo, Markku;
Ungureanu, Daniela

Publication type:

Article

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

Published in:

Nature Methods, 2013, v. 10, n. 4, p. 307, doi. 10.1038/nmeth.2400

By:

Varjosalo, Markku;
Sacco, Roberto;
Stukalov, Alexey;
van Drogen, Audrey;
Planyavsky, Melanie;
Hauri, Simon;
Aebersold, Ruedi;
Bennett, Keiryn L;
Colinge, Jacques;
Gstaiger, Matthias;
Superti-Furga, Giulio

Publication type:

Article

Proximity interactome of alphavirus replicase component nsP3 includes proviral host factors eIF4G and AHNAK.

Published in:

PLoS Pathogens, 2025, v. 21, n. 4, p. 1, doi. 10.1371/journal.ppat.1013050

By:

Thiruvaiyaru, Aditya;
Mattila, Sari;
Sadeghi, Mohammadreza;
Naumenko, Krystyna;
Merits, Andres;
Varjosalo, Markku;
Ahola, Tero

Publication type:

Article

Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity.

Published in:

Science Immunology, 2021, v. 6, n. 65, p. 1, doi. 10.1126/sciimmunol.abe3981

By:

Shahin, Tala;
Kuehn, Hye Sun;
Shoeb, Mohamed R.;
Gawriyski, Lisa;
Giuliani, Sarah;
Repiscak, Peter;
Hoeger, Birgit;
Petronczki, Özlem Yüce;
Bal, Sevgi Köstel;
Zoghi, Samaneh;
Dmytrus, Jasmin;
Seruggia, Davide;
Castanon\, Irinka;
Rezaei, Nima;
Varjosalo, Markku;
Halbritter, Florian;
Rosenzweig, Sergio D.;
Boztug, Kaan

Publication type:

Article

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.

Published in:

Journal of Cell Biology, 2013, v. 201, n. 3, p. 467, doi. 10.1083/jcb.201205176

By:

Sugiyama, Nami;
Gucciardo, Erika;
Tatti, Olga;
Varjosalo, Markku;
Hyytiäinen, Marko;
Gstaiger, Matthias;
Lehti, Kaisa

Publication type:

Article

A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1.

Published in:

Journal of Biochemistry, 2020, v. 168, n. 5, p. 515, doi. 10.1093/jb/mvaa067

By:

Cózar, Jose M González de;
Carretero-Junquera, Maria;
Ciesielski, Grzegorz L;
Miettinen, Sini M;
Varjosalo, Markku;
Kaguni, Laurie S;
Dufour, Eric;
Jacobs, Howard T

Publication type:

Article

CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 16, p. 9489, doi. 10.3390/ijms23169489

By:

Eesmaa, Ave;
Yu, Li-Ying;
Göös, Helka;
Danilova, Tatiana;
Nõges, Kristofer;
Pakarinen, Emmi;
Varjosalo, Markku;
Lindahl, Maria;
Lindholm, Päivi;
Saarma, Mart

Publication type:

Article

Colonic metaproteomic signatures of active bacteria and the host in obesity.

Published in:

Proteomics, 2015, v. 15, n. 20, p. 3544, doi. 10.1002/pmic.201500049

By:

Kolmeder, Carolin A.;
Ritari, Jarmo;
Verdam, Froukje J.;
Muth, Thilo;
Keskitalo, Salla;
Varjosalo, Markku;
Fuentes, Susana;
Greve, Jan Willem;
Buurman, Wim A.;
Reichl, Udo;
Rapp, Erdmann;
Martens, Lennart;
Palva, Airi;
Salonen, Anne;
Rensen, Sander S.;
Vos, Willem M.

Publication type:

Article

Navigating through metaproteomics data: A logbook of database searching.

Published in:

Proteomics, 2015, v. 15, n. 20, p. 3439, doi. 10.1002/pmic.201400560

By:

Muth, Thilo;
Kolmeder, Carolin A.;
Salojärvi, Jarkko;
Keskitalo, Salla;
Varjosalo, Markku;
Verdam, Froukje J.;
Rensen, Sander S.;
Reichl, Udo;
Vos, Willem M.;
Rapp, Erdmann;
Martens, Lennart

Publication type:

Article