Works by Suthar, Mehul S.

Results: 39

Dendritic cell-associated MAVS is required to control West Nile virus replication and ensuing humoral immune responses.
Published in:
PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218928
By:
- Roe, Kelsey;
- Giordano, Daniela;
- Young, Lucy B.;
- Draves, Kevin E.;
- Holder, Ursula;
- Suthar, Mehul S.;
- Jr.Gale, Michael;
- Clark, Edward A.
Publication type:
Article
SARS-CoV-2 Viral Shedding and Rapid Antigen Test Performance -- Respiratory Virus Transmission Network, November 2022--May 2023.
Published in:
MMWR: Morbidity & Mortality Weekly Report, 2024, v. 73, n. 16, p. 365, doi. 10.15585/mmwr.mm7316a2
By:
- Smith-Jeffcoat, Sarah E.;
- Mellis, Alexandra M.;
- Grijalva, Carlos G.;
- Talbot, H. Keipp;
- Schmitz, Jonathan;
- Lutrick, Karen;
- Ellingson, Katherine D.;
- Stockwell, Melissa S.;
- McLaren, Son H.;
- Nguyen, Huong Q.;
- Rao, Suchitra;
- Asturias, Edwin J.;
- Davis-Gardner, Meredith E.;
- Suthar, Mehul S.;
- Kirking, Hannah L.
Publication type:
Article
Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis.
Published in:
PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004086
By:
- Pinto, Amelia K.;
- Ramos, Hilario J.;
- Wu, Xiaobo;
- Aggarwal, Shilpa;
- Shrestha, Bimmi;
- Gorman, Matthew;
- Kim, Kristin Y.;
- Suthar, Mehul S.;
- Atkinson, John P.;
- Gale Jr, Michael;
- Diamond, Michael S.
Publication type:
Article
Innate Immune Sensing of Flaviviruses.
Published in:
PLoS Pathogens, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.ppat.1003541
By:
- Suthar, Mehul S.;
- Aguirre, Sebastian;
- Fernandez-Sesma, Ana
Publication type:
Article
A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes.
Published in:
PLoS Pathogens, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.ppat.1003168
By:
- Suthar, Mehul S.;
- Brassil, Margaret M.;
- Blahnik, Gabriele;
- McMillan, Aimee;
- Ramos, Hilario J.;
- Proll, Sean C.;
- Belisle, Sarah E.;
- Katze, Michael G.;
- Gale Jr., Michael
Publication type:
Article
IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling.
Published in:
PLoS Pathogens, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.ppat.1003118
By:
- Lazear, Helen M.;
- Lancaster, Alissa;
- Wilkins, Courtney;
- Suthar, Mehul S.;
- Huang, Albert;
- Vick, Sarah C.;
- Clepper, Lisa;
- Thackray, Larissa;
- Brassil, Margaret M.;
- Virgin, Herbert W.;
- Nikolich-Zugich, Janko;
- Moses, Ashlee V.;
- Gale, Jr., Michael;
- Früh, Klaus;
- Diamond, Michael S.
Publication type:
Article
IL-1β Signaling Promotes CNS-Intrinsic Immune Control of West Nile Virus Infection.
Published in:
PLoS Pathogens, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.ppat.1003039
By:
- Ramos, Hilario J.;
- Lanteri, Marion C.;
- Blahnik, Gabriele;
- Negash, Amina;
- Suthar, Mehul S.;
- Brassil, Margaret M.;
- Sodhi, Khushbu;
- Treuting, Piper M.;
- Busch, Michael P.;
- Norris, Philip J.;
- Gale Jr., Michael
Publication type:
Article
Interferon Regulatory Factor-1 (IRF-1) Shapes Both Innate and CD8<sup>+</sup> T Cell Immune Responses against West Nile Virus Infection.
Published in:
PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002230
By:
- Brien, James D.;
- Daffis, Stephane;
- Lazear, Helen M.;
- Cho, Hyelim;
- Suthar, Mehul S.;
- Gale Jr., Michael;
- Diamond, Michael S.
Publication type:
Article
Rabies Virus Infection Induces Type I Interferon Production in an IPS-1 Dependent Manner While Dendritic Cell Activation Relies on IFNAR Signaling.
Published in:
PLoS Pathogens, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.ppat.1001016
By:
- Faul, Elizabeth J.;
- Wanjalla, Celestine N.;
- Suthar, Mehul S.;
- Gale Jr., Michael;
- Wirblich, Christoph;
- Schnell, Matthias J.
Publication type:
Article
IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity.
Published in:
PLoS Pathogens, 2010, v. 6, n. 2, p. 1, doi. 10.1371/journal.ppat.1000757
By:
- Suthar, Mehul S.;
- Ma, Daphne Y.;
- Thomas, Sunil;
- Lund, Jennifer M.;
- Nu Zhang;
- Daffis, Stephane;
- Rudensky, Alexander Y.;
- Bevan, Michael J.;
- Clark, Edward A.;
- Kaja, Murali-Krishna;
- Diamond, Michael S.;
- Gale Jr., Michael
Publication type:
Article
Induction of IFN-β and the Innate Antiviral Response in Myeloid Cells Occurs through an IPS-1-Dependent Signal That Does Not Require IRF-3 and IRF-7.
Published in:
PLoS Pathogens, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.ppat.1000607
By:
- Daffis, Stephane;
- Suthar, Mehul S.;
- Szretter, Kristy J.;
- Gale Jr., Michael;
- Diamond, Michael S.
Publication type:
Article
A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41850-7
By:
- von Beck, Troy;
- Navarrete, Karla;
- Arce, Nicholas A.;
- Gao, Mu;
- Dale, Gordon A.;
- Davis-Gardner, Meredith E.;
- Floyd, Katharine;
- Mena Hernandez, Luis;
- Mullick, Nikita;
- Vanderheiden, Abigail;
- Skountzou, Ioanna;
- Kuchipudi, Suresh V.;
- Saravanan, Rathi;
- Li, Renhao;
- Skolnick, Jeffrey;
- Suthar, Mehul S.;
- Jacob, Joshy
Publication type:
Article
A wild boar cathelicidin peptide derivative inhibits severe acute respiratory syndrome coronavirus-2 and its drifted variants.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41850-7
By:
- von Beck, Troy;
- Navarrete, Karla;
- Arce, Nicholas A.;
- Gao, Mu;
- Dale, Gordon A.;
- Davis-Gardner, Meredith E.;
- Floyd, Katharine;
- Mena Hernandez, Luis;
- Mullick, Nikita;
- Vanderheiden, Abigail;
- Skountzou, Ioanna;
- Kuchipudi, Suresh V.;
- Saravanan, Rathi;
- Li, Renhao;
- Skolnick, Jeffrey;
- Suthar, Mehul S.;
- Jacob, Joshy
Publication type:
Article
Atovaquone and Pibrentasvir Inhibit the SARS-CoV-2 Endoribonuclease and Restrict Infection In Vitro but Not In Vivo.
Published in:
Viruses (1999-4915), 2023, v. 15, n. 9, p. 1841, doi. 10.3390/v15091841
By:
- von Beck, Troy;
- Mena Hernandez, Luis;
- Zhou, Hongyi;
- Floyd, Katharine;
- Suthar, Mehul S.;
- Skolnick, Jeffrey;
- Jacob, Joshy
Publication type:
Article
Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity.
Published in:
2017
By:
- Priyamvada, Lalita;
- Suthar, Mehul S.;
- Ahmed, Rafi;
- Wrammert, Jens
Publication type:
journal article
AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans.
Published in:
Science Immunology, 2024, v. 9, n. 94, p. 1, doi. 10.1126/sciimmunol.adi8039
By:
- Grigoryan, Lilit;
- Feng, Yupeng;
- Bellusci, Lorenza;
- Lai, Lilin;
- Wali, Bushra;
- Ellis, Madison;
- Yuan, Meng;
- Arunachalam, Prabhu S.;
- Hu, Mengyun;
- Kowli, Sangeeta;
- Gupta, Sheena;
- Maysel-Auslender, Sofia;
- Maecker, Holden T.;
- Samaha, Hady;
- Rouphael, Nadine;
- Wilson, Ian A.;
- Moreno, Alberto C.;
- Suthar, Mehul S.;
- Khurana, Surender;
- Pillet, Stéphane
Publication type:
Article
Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination.
Published in:
2021
By:
- Edara, Venkata Viswanadh;
- Hudson, William H.;
- Xie, Xuping;
- Ahmed, Rafi;
- Suthar, Mehul S.
Publication type:
journal article
Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells.
Published in:
PLoS Pathogens, 2017, v. 13, n. 2, p. 1, doi. 10.1371/journal.ppat.1006164
By:
- Bowen, James R.;
- Quicke, Kendra M.;
- Maddur, Mohan S.;
- O’Neal, Justin T.;
- McDonald, Circe E.;
- Fedorova, Nadia B.;
- Puri, Vinita;
- Shabman, Reed S.;
- Pulendran, Bali;
- Suthar, Mehul S.
Publication type:
Article
Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
Published in:
Viruses (1999-4915), 2019, v. 11, n. 1, p. 19, doi. 10.3390/v11010019
By:
- Bhaumik, Siddhartha K.;
- Priyamvada, Lalita;
- Kauffman, Robert C.;
- Lai, Lilin;
- Natrajan, Muktha S.;
- Cho, Alice;
- Rouphael, Nadine;
- Suthar, Mehul S.;
- Mulligan, Mark J.;
- Wrammert, Jens
Publication type:
Article
The Innate Immune Playbook for Restricting West Nile Virus Infection.
Published in:
Viruses (1999-4915), 2013, v. 5, n. 11, p. 2643, doi. 10.3390/v5112643
By:
- Quicke, Kendra M.;
- Suthar, Mehul S.
Publication type:
Article
Immune responses and therapeutic challenges in paediatric patients with new‐onset acute myeloid leukaemia and concomitant COVID‐19.
Published in:
British Journal of Haematology, 2021, v. 194, n. 3, p. 549, doi. 10.1111/bjh.17517
By:
- Patel, Pratik A.;
- Lapp, Stacey A.;
- Grubbs, Gabrielle;
- Edara, Venkata V.;
- Rostad, Christina A.;
- Stokes, Claire L.;
- Pauly, Melinda G.;
- Anderson, Evan J.;
- Piantadosi, Anne;
- Suthar, Mehul S.;
- Khurana, Surender;
- Sabnis, Himalee S.
Publication type:
Article
Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS‐CoV‐2 infection and COVID‐19 disease severity.
Published in:
FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202300077R
By:
- Tedbury, Philip R.;
- Manfredi, Candela;
- Degenhardt, Frauke;
- Conway, Joseph;
- Horwath, Michael C.;
- McCracken, Courtney;
- Sorscher, Adam J.;
- Moreau, Sandy;
- Wright, Christine;
- Edwards, Carolina;
- Brewer, Jo;
- Guarner, Jeannette;
- de Wit, Emmie;
- Williamson, Brandi N.;
- Suthar, Mehul S.;
- Ong, Yee T.;
- Roback, John D.;
- Alter, David N.;
- Holter, Jan C.;
- Karlsen, Tom H.
Publication type:
Article
West Nile virus infection and immunity.
Published in:
Nature Reviews Microbiology, 2013, v. 11, n. 2, p. 115, doi. 10.1038/nrmicro2950
By:
- Suthar, Mehul S.;
- Diamond, Michael S.;
- Gale Jr, Michael
Publication type:
Article
Divergence of variant antibodies following SARS-CoV-2 booster vaccines in myeloma and impact of hybrid immunity.
Published in:
NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00999-6
By:
- Moreno, Alberto;
- Manning, Kelly;
- Azeem, Maryam I.;
- Nooka, Ajay K.;
- Ellis, Madison;
- Manalo, Renee Julia;
- Switchenko, Jeffrey M.;
- Wali, Bushra;
- Kaufman, Jonathan L.;
- Hofmeister, Craig C.;
- Joseph, Nisha S.;
- Lonial, Sagar;
- Dhodapkar, Kavita M.;
- Dhodapkar, Madhav V.;
- Suthar, Mehul S.
Publication type:
Article
Strong T<sub>H</sub>1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
Published in:
Science Translational Medicine, 2019, v. 11, n. 519, p. 1, doi. 10.1126/scitranslmed.aav1800
By:
- Chamcha, Venkateswarlu;
- Reddy, Pradeep B. J.;
- Kannanganat, Sunil;
- Wilkins, Courtney;
- Gangadhara, Sailaja;
- Velu, Vijayakumar;
- Green, Richard;
- Law, G. Lynn;
- Chang, Jean;
- Bowen, James R.;
- Kozlowski, Pamela A.;
- Lifton, Michelle;
- Santra, Sampa;
- Legere, Traci;
- Chea, Lynette S.;
- Chennareddi, Lakshmi;
- Yu, Tianwei;
- Suthar, Mehul S.;
- Silvestri, Guido;
- Derdeyn, Cynthia A.
Publication type:
Article
Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice.
Published in:
EMBO Reports, 2023, v. 24, n. 4, p. 1, doi. 10.15252/embr.202256660
By:
- Kenney, Adam D;
- Zani, Ashley;
- Kawahara, Jeffrey;
- Eddy, Adrian C;
- Wang, Xiao‐Liang;
- Mahesh, KC;
- Lu, Mijia;
- Thomas, Jeronay;
- Kohlmeier, Jacob E;
- Suthar, Mehul S;
- Hemann, Emily A;
- Li, Jianrong;
- Peeples, Mark E;
- Hall‐Stoodley, Luanne;
- Forero, Adriana;
- Cai, Chuanxi;
- Ma, Jianjie;
- Yount, Jacob S
Publication type:
Article
Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses.
Published in:
Cellular Microbiology, 2009, v. 11, n. 6, p. 880, doi. 10.1111/j.1462-5822.2009.01311.x
By:
- Suthar, Mehul S.;
- Gale Jr., Michael;
- Owen, David M.
Publication type:
Article
Timing of exposure is critical in a highly sensitive model of SARS-CoV-2 transmission.
Published in:
PLoS Pathogens, 2022, v. 18, n. 3, p. 1, doi. 10.1371/journal.ppat.1010181
By:
- Ganti, Ketaki;
- Ferreri, Lucas M.;
- Lee, Chung-Young;
- Bair, Camden R.;
- Delima, Gabrielle K.;
- Holmes, Kate E.;
- Suthar, Mehul S.;
- Lowen, Anice C.
Publication type:
Article
Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16320-7
By:
- Raper, Jessica;
- Kovacs-Balint, Zsofia;
- Mavigner, Maud;
- Gumber, Sanjeev;
- Burke, Mark W.;
- Habib, Jakob;
- Mattingly, Cameron;
- Fair, Damien;
- Earl, Eric;
- Feczko, Eric;
- Styner, Martin;
- Jean, Sherrie M.;
- Cohen, Joyce K.;
- Suthar, Mehul S.;
- Sanchez, Mar M.;
- Alvarado, Maria C.;
- Chahroudi, Ann
Publication type:
Article
An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination.
Published in:
Science Translational Medicine, 2023, v. 15, n. 683, p. 1, doi. 10.1126/scitranslmed.abo2847
By:
- Carreño, Juan Manuel;
- Raskin, Ariel;
- Singh, Gagandeep;
- Tcheou, Johnstone;
- Kawabata, Hisaaki;
- Gleason, Charles;
- Srivastava, Komal;
- Vigdorovich, Vladimir;
- Dambrauskas, Nicholas;
- Gupta, Sneh Lata;
- González Domínguez, Irene;
- Martinez, Jose Luis;
- Slamanig, Stefan;
- Sather, D. Noah;
- Raghunandan, Rama;
- Wirachwong, Ponthip;
- Muangnoicharoen, Sant;
- Pitisuttithum, Punnee;
- Wrammert, Jens;
- Suthar, Mehul S.
Publication type:
Article
Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection.
Published in:
PLoS ONE, 2021, v. 16, n. 8, p. 1, doi. 10.1371/journal.pone.0256482
By:
- Lapp, Stacey A.;
- Edara, Venkata Viswanadh;
- Lu, Austin;
- Lai, Lilin;
- Hussaini, Laila;
- Chahroudi, Ann;
- Anderson, Larry J.;
- Suthar, Mehul S.;
- Anderson, Evan J.;
- Rostad, Christina A.
Publication type:
Article
The amphibian peptide Yodha is virucidal for Zika and dengue viruses.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80596-4
By:
- Lee, Song Hee;
- Kim, Eui Ho;
- O'neal, Justin T.;
- Dale, Gordon;
- Holthausen, David J.;
- Bowen, James R.;
- Quicke, Kendra M.;
- Skountzou, Ioanna;
- Gopal, Shyla;
- George, Sanil;
- Wrammert, Jens;
- Suthar, Mehul S.;
- Jacob, Joshy
Publication type:
Article
Rapid Detection and Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Omicron Variant in a Returning Traveler.
Published in:
Clinical Infectious Diseases, 2022, v. 75, n. 1, p. e350, doi. 10.1093/cid/ciac032
By:
- Sexton, Mary Elizabeth;
- Waggoner, Jesse J;
- Carmola, Ludy R;
- Nguyen, Phuong Vi;
- Wang, Ethan;
- Khosravi, Dara;
- Taz, Azmain;
- Arthur, Robert A;
- Patel, Mit;
- Edara, Venkata Viswanadh;
- Foster, Stephanie L;
- Moore, Kathryn M;
- Gagne, Matthew;
- Roberts-Torres, Jesmine;
- Henry, Amy R;
- Godbole, Sucheta;
- Douek, Daniel C;
- Rouphael, Nadine;
- Suthar, Mehul S;
- Piantadosi, Anne
Publication type:
Article
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.
Published in:
PLoS Biology, 2021, v. 19, n. 11, p. 1, doi. 10.1371/journal.pbio.3001284
By:
- Muruato, Antonio;
- Vu, Michelle N.;
- Johnson, Bryan A.;
- Davis-Gardner, Meredith E.;
- Vanderheiden, Abigail;
- Lokugamage, Kumari;
- Schindewolf, Craig;
- Crocquet-Valdes, Patricia A.;
- Langsjoen, Rose M.;
- Plante, Jessica A.;
- Plante, Kenneth S.;
- Weaver, Scott C.;
- Debbink, Kari;
- Routh, Andrew L.;
- Walker, David;
- Suthar, Mehul S.;
- Shi, Pei-Yong;
- Xie, Xuping;
- Menachery, Vineet D.
Publication type:
Article
Influenza Virus-like Particle-Based Hybrid Vaccine Containing RBD Induces Immunity against Influenza and SARS-CoV-2 Viruses.
Published in:
Vaccines, 2022, v. 10, n. 6, p. N.PAG, doi. 10.3390/vaccines10060944
By:
- Bommireddy, Ramireddy;
- Stone, Shannon;
- Bhatnagar, Noopur;
- Kumari, Pratima;
- Munoz, Luis E.;
- Oh, Judy;
- Kim, Ki-Hye;
- Berry, Jameson T. L.;
- Jacobsen, Kristen M.;
- Jaafar, Lahcen;
- Naing, Swe-Htet;
- Blackerby, Allison N.;
- Gaag, Tori Van der;
- Wright, Chloe N.;
- Lai, Lilin;
- Pack, Christopher D.;
- Ramachandiran, Sampath;
- Suthar, Mehul S.;
- Kang, Sang-Moo;
- Kumar, Mukesh
Publication type:
Article
Negative regulators of the RIG-I-like receptor signaling pathway.
Published in:
European Journal of Immunology, 2017, v. 47, n. 4, p. 615, doi. 10.1002/eji.201646484
By:
- Quicke, Kendra M.;
- Diamond, Michael S.;
- Suthar, Mehul S.
Publication type:
Article
SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19808-4
By:
- Zhang, Lizhou;
- Jackson, Cody B.;
- Mou, Huihui;
- Ojha, Amrita;
- Peng, Haiyong;
- Quinlan, Brian D.;
- Rangarajan, Erumbi S.;
- Pan, Andi;
- Vanderheiden, Abigail;
- Suthar, Mehul S.;
- Li, Wenhui;
- Izard, Tina;
- Rader, Christoph;
- Farzan, Michael;
- Choe, Hyeryun
Publication type:
Article
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19231-9
By:
- Hurlburt, Nicholas K.;
- Seydoux, Emilie;
- Wan, Yu-Hsin;
- Edara, Venkata Viswanadh;
- Stuart, Andrew B.;
- Feng, Junli;
- Suthar, Mehul S.;
- McGuire, Andrew T.;
- Stamatatos, Leonidas;
- Pancera, Marie
Publication type:
Article
Measure and Countermeasure: Type I IFN (IFN-α/β) Antiviral Response against West Nile Virus.
Published in:
Journal of Innate Immunity, 2009, v. 1, n. 5, p. 435, doi. 10.1159/000226248
By:
- Daffis, Stephane;
- Suthar, Mehul S.;
- Gale, Jr., Michael;
- Diamond, Michael S.
Publication type:
Article