Works by Stern, Lawrence J.

Results: 42

Exploring the role of T cells in Alzheimer's and other neurodegenerative diseases: Emerging therapeutic insights from the T Cells in the Brain symposium.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 2, p. 1, doi. 10.1002/alz.14548

By:

Elyaman, Wassim;
Stern, Lawrence J.;
Jiang, Ning;
Dressman, Dallin;
Bradley, Philip;
Klatzmann, David;
Bradshaw, Elizabeth M.;
Farber, Donna L.;
Kent, Sally C.;
Chizari, Shahab;
Funk, Kristen;
Devanand, Davangere;
Thakur, Kiran T.;
Raj, Towfique;
Dalahmah, Osama Al;
Sarkis, Rani A.;
Weiner, Howard L.;
Shneider, Neil A.;
Przedborski, Serge

Publication type:

Article

HLA-DM focuses on conformational flexibility around P1 pocket to catalyze peptide exchange.

Published in:

Frontiers in Immunology, 2013, v. 4, p. 1, doi. 10.3389/fimmu.2013.00336

By:

Yin, Liusong;
Stern, Lawrence J.

Publication type:

Article

Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25564-w

By:

Maben, Zachary;
Arya, Richa;
Georgiadis, Dimitris;
Stratikos, Efstratios;
Stern, Lawrence J.

Publication type:

Article

Structure and thermal stability of monomeric bacteriorhodopsin in mixed pospholipid/detergent micelles.

Published in:

Proteins, 1989, v. 5, n. 1, p. 38, doi. 10.1002/prot.340050106

By:

Brouillette, Christie G.;
McMichens, Ruth B.;
Stern, Lawrence J.;
Khorana, H. Gobind

Publication type:

Article

Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine-185 protonates and deprotonantes during the photocycle.

Published in:

Proteins, 1988, v. 3, n. 4, p. 219, doi. 10.1002/prot.340030403

By:

Braiman, Mark S.;
Mogi, Tatsushi;
Stern, Lawrence J.;
Hackett, Neil R.;
Chao, Betty H.;
Khorana, H. Gobind;
Rothschild, Kenneth J.

Publication type:

Article

Naturally processed HLA‐DR3‐restricted HHV‐6B peptides are recognized broadly with polyfunctional and cytotoxic CD4 T‐cell responses.

Published in:

European Journal of Immunology, 2019, v. 49, n. 8, p. 1167, doi. 10.1002/eji.201948126

By:

Becerra‐Artiles, Aniuska;
Cruz, John;
Leszyk, John D.;
Sidney, John;
Sette, Alessandro;
Shaffer, Scott A.;
Stern, Lawrence J.

Publication type:

Article

Author Correction: Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism.

Published in:

2023

By:

Maben, Zachary;
Arya, Richa;
Georgiadis, Dimitris;
Stratikos, Efstratios;
Stern, Lawrence J.

Publication type:

Correction Notice

Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.

Published in:

Gut Microbes, 2017, v. 8, n. 6, p. 544, doi. 10.1080/19490976.2017.1339006

By:

Maldonado-Contreras, Ana;
Birtley, James R.;
Boll, Erik;
Zhao, Yun;
Mumy, Karen L.;
Toscano, Juan;
Ayehunie, Seyoum;
Reinecker, Hans-Christian;
Stern, Lawrence J.;
McCormick, Beth A.

Publication type:

Article

CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.

Published in:

PLoS Pathogens, 2019, v. 15, n. 11, p. 1, doi. 10.1371/journal.ppat.1008122

By:

Kamga, Larisa;
Gil, Anna;
Song, Inyoung;
Brody, Robin;
Ghersi, Dario;
Aslan, Nuray;
Stern, Lawrence J.;
Selin, Liisa K.;
Luzuriaga, Katherine

Publication type:

Article

Tetherin/BST-2 Antagonism by Nef Depends on a Direct Physical Interaction between Nef and Tetherin, and on Clathrin-mediated Endocytosis.

Published in:

PLoS Pathogens, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.ppat.1003487

By:

Serra-Moreno, Ruth;
Zimmermann, Kerstin;
Stern, Lawrence J.;
Evans, David T.

Publication type:

Article

Human CD4 T Cell Epitopes from Vaccinia Virus Induced by Vaccination or Infection.

Published in:

PLoS Pathogens, 2007, v. 3, n. 10, p. e144, doi. 10.1371/journal.ppat.0030144

By:

Calvo-Calle, J. Mauricio;
Strug, Iwona;
Nastke, Maria-Dorothea;
Baker, Stephen P.;
Stern, Lawrence J.

Publication type:

Article

Structure Induction of the T-Cell Receptor ζ-Chain upon Lipid Binding Investigated by NMR Spectroscopy.

Published in:

ChemBioChem, 2007, v. 8, n. 7, p. 820, doi. 10.1002/cbic.200600413

By:

Duchardt, Elke;
Sigalov, Alexander B.;
Aivazian, Dikran;
Stern, Lawrence J.;
Schwalbe, Harald

Publication type:

Article

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1).

Published in:

Cancer Immunology, Immunotherapy, 2019, v. 68, n. 8, p. 1245, doi. 10.1007/s00262-019-02358-0

By:

Koumantou, Despoina;
Barnea, Eilon;
Martin-Esteban, Adrian;
Maben, Zachary;
Papakyriakou, Athanasios;
Mpakali, Anastasia;
Kokkala, Paraskevi;
Pratsinis, Harris;
Georgiadis, Dimitris;
Stern, Lawrence J.;
Admon, Arie;
Stratikos, Efstratios

Publication type:

Article

MHC class II function preserved by low-affinity peptide interactions preceding stable binding.

Published in:

Nature, 1994, v. 370, n. 6491, p. 647, doi. 10.1038/370647a0

By:

Sadegh-Nasseri, Scheherazade;
Stern, Lawrence J.

Publication type:

Article

Binary and ternary complexes between T-cell receptor, class II MHC and superantigen `in vitro'.

Published in:

Nature, 1994, v. 369, n. 6478, p. 324, doi. 10.1038/369324a0

By:

Seth, Alpna;
Stern, Lawrence J.

Publication type:

Article

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus...

Published in:

Nature, 1994, v. 368, n. 6468, p. 215, doi. 10.1038/368215a0

By:

Stern, Lawrence J.;
Brown, Jerry H.

Publication type:

Article

Quantitative Profiling of the Lymph Node Clearance Capacity.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-29614-0

By:

Clement, Cristina C.;
Wang, Wei;
Dzieciatkowska, Monika;
Cortese, Marco;
Hansen, Kirk C.;
Becerra, Aniuska;
Thangaswamy, Sangeetha;
Nizamutdinova, Irina;
Moon, Jee-Young;
Stern, Lawrence J.;
Gashev, Anatoliy A.;
Zawieja, David;
Santambrogio, Laura

Publication type:

Article

The HHV-6B U20 glycoprotein binds ULBP1, masking it from recognition by NKG2D and interfering with natural killer cell activation.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1363156

By:

Weaver, Grant C.;
Schneider, Christine L.;
Becerra-Artiles, Aniuska;
Clayton, Kiera L.;
Hudson, Amy W.;
Stern, Lawrence J.

Publication type:

Article

The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release.

Published in:

PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0199704

By:

Negroni, Maria Pia;
Stern, Lawrence J.

Publication type:

Article

Class II major histocompatibility complex tetramer staining: progress, problems, and prospects.

Published in:

Immunology, 2008, v. 123, n. 3, p. 305, doi. 10.1111/j.1365-2567.2007.02801.x

By:

Vollers, Sabrina S.;
Stern, Lawrence J.

Publication type:

Article

Phosphorylation of T cell receptor ζ is regulated by a lipid dependent folding transition.

Published in:

Nature Structural Biology, 2000, v. 7, n. 11, p. 1023

By:

Aivazian, Dikran;
Stern, Lawrence J.

Publication type:

Article

Conformational variation in structures of classical and non-classical MHCII proteins and functional implications.

Published in:

Immunological Reviews, 2012, v. 250, n. 1, p. 144, doi. 10.1111/imr.12003

By:

Painter, Corrie A.;
Stern, Lawrence J.

Publication type:

Article

Distinguishing Signal From Noise in Immunopeptidome Studies of Limiting-Abundance Biological Samples: Peptides Presented by I-Ab in C57BL/6 Mouse Thymus.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.658601

By:

Nanaware, Padma P.;
Jurewicz, Mollie M.;
Clement, Cristina C.;
Lu, Liying;
Santambrogio, Laura;
Stern, Lawrence J.

Publication type:

Article

Immunopeptidome profiling of human coronavirus OC43-infected cells identifies CD4 T-cell epitopes specific to seasonal coronaviruses or cross-reactive with SARS-CoV-2.

Published in:

PLoS Pathogens, 2023, v. 19, n. 7, p. 1, doi. 10.1371/journal.ppat.1011032

By:

Becerra-Artiles, Aniuska;
Nanaware, Padma P.;
Muneeruddin, Khaja;
Weaver, Grant C.;
Shaffer, Scott A.;
Calvo-Calle, J. Mauricio;
Stern, Lawrence J.

Publication type:

Article

HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 90, doi. 10.1038/nsmb.2460

By:

Guce, Abigail I;
Mortimer, Sarah E;
Yoon, Taejin;
Painter, Corrie A;
Jiang, Wei;
Mellins, Elizabeth D;
Stern, Lawrence J

Publication type:

Article

Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 604, doi. 10.1038/nsmb.2021

By:

Nguyen, Tina T.;
Shih-Chung Chang;
Evnouchidou, Irini;
York, Ian A.;
Zikos, Christos;
Rock, Kenneth L.;
Goldberg, Alfred L.;
Stratikos, Efstratios;
Stern, Lawrence J.

Publication type:

Article

A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B.

Published in:

PLoS ONE, 2015, v. 10, n. 11, p. 1, doi. 10.1371/journal.pone.0142871

By:

Becerra-Artiles, Aniuska;
Dominguez-Amorocho, Omar;
Stern, Lawrence J.;
Calvo-Calle, J. Mauricio

Publication type:

Article

An Unstable Th Epitope of P. falciparum Fosters Central Memory T Cells and Anti-CS Antibody Responses.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100639

By:

Parra-López, Carlos A.;
Bernal-Estévez, David;
Vargas, Luis Eduardo;
Pulido-Calixto, Carolina;
Salazar, Luz Mary;
Calvo-Calle, J. Mauricio;
Stern, Lawrence J.

Publication type:

Article

Peptide-MHC Cellular Microarray with Innovative Data Analysis System for Simultaneously Detecting Multiple CD4 T-Cell Responses.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0011355

By:

Xinhui Ge;
Gebe, John A.;
Bollyky, Paul L.;
James, Eddie A.;
Junbao Yang;
Stern, Lawrence J.;
Kwok, William W.

Publication type:

Article

An Expanded Self-Antigen Peptidome Is Carried by the Human Lymph As Compared to the Plasma.

Published in:

PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009863

By:

Clement, Cristina C.;
Cannizzo, Elvira S.;
Nastke, Maria-Dorothea;
Sahu, Ranjit;
Olszewski, Waldemar;
Miller, Norman E.;
Stern, Lawrence J.;
Santambrogio, Laura

Publication type:

Article

Model for the Peptide-Free Conformation of Class II MHC Proteins.

Published in:

PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002403

By:

Painter, Corrie A.;
Cruz, Anthony;
López, Gustavo E.;
Stern, Lawrence J.;
Zavala-Ruiz, Zarixia

Publication type:

Article

Class II MHC antigen processing in immune tolerance and inflammation.

Published in:

Immunogenetics, 2019, v. 71, n. 3, p. 171, doi. 10.1007/s00251-018-1095-x

By:

Jurewicz, Mollie M.;
Stern, Lawrence J.

Publication type:

Article

Examination of the highly diverse CD4+ T-cell repertoire directed against an influenza peptide: a step towards TCR proteomics.

Published in:

Immunogenetics, 2002, v. 54, n. 9, p. 611, doi. 10.1007/s00251-002-0508-y

By:

Cameron, Thomas O.;
Cohen, George B.;
Islam, Sabina A.;
Stern, Lawrence J.

Publication type:

Article

Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells.

Published in:

Nature Chemical Biology, 2007, v. 3, n. 4, p. 222, doi. 10.1038/nchembio868

By:

Venkatraman, Prasanna;
Nguyen, Tina T.;
Sainlos, Matthieu;
Bilsel, Osman;
Chitta, Sriram;
Imperiali, Barbara;
Stern, Lawrence J.

Publication type:

Article

Noble metals strip peptides from class II MHC proteins.

Published in:

Nature Chemical Biology, 2006, v. 2, n. 4, p. 197, doi. 10.1038/nchembio773

By:

De Wall, Stephen L.;
Painter, Corrie;
Stone, Jennifer D.;
Bandaranayake, Rajintha;
Wiley, Don C.;
Mitchison, Timothy J.;
Stern, Lawrence J.;
DeDecker, Brian S.

Publication type:

Article

Evaluation of a method to measure HHV-6B infection in vitro based on cell size.

Published in:

Virology Journal, 2018, v. 15, p. 1, doi. 10.1186/s12985-017-0917-z

By:

Becerra-Artiles, Aniuska;
Santoro, Tessa;
Stern, Lawrence J.

Publication type:

Article

Corrigendum: Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7.

Published in:

2022

By:

Weaver, Grant C.;
Arya, Richa;
Schneider, Christine L.;
Hudson, Amy W.;
Stern, Lawrence J.

Publication type:

Correction Notice

Structural Models for Roseolovirus U20 And U21: Non-Classical MHC-I Like Proteins From HHV-6A, HHV-6B, and HHV-7.

Published in:

Frontiers in Immunology, 2022, v. 13, p. N.PAG, doi. 10.3389/fimmu.2022.864898

By:

Weaver, Grant C.;
Arya, Richa;
Schneider, Christine L.;
Hudson, Amy W.;
Stern, Lawrence J.

Publication type:

Article

Author Correction: In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls.

Published in:

2020

By:

Jiang, Wei;
Birtley, James R.;
Hung, Shu-Chen;
Wang, Weiqi;
Chiou, Shin-Heng;
Macaubas, Claudia;
Kornum, Birgitte;
Tian, Lu;
Huang, Huang;
Adler, Lital;
Weaver, Grant;
Lu, Liying;
Ilstad-Minnihan, Alexandra;
Somasundaram, Sriram;
Ayyangar, Sashi;
Davis, Mark M.;
Stern, Lawrence J.;
Mellins, Elizabeth D.

Publication type:

Correction Notice

In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13234-x

By:

Jiang, Wei;
Birtley, James R.;
Hung, Shu-Chen;
Wang, Weiqi;
Chiou, Shin-Heng;
Macaubas, Claudia;
Kornum, Birgitte;
Tian, Lu;
Huang, Huang;
Adler, Lital;
Weaver, Grant;
Lu, Liying;
Ilstad-Minnihan, Alexandra;
Somasundaram, Sriram;
Ayyangar, Sashi;
Davis, Mark M.;
Stern, Lawrence J.;
Mellins, Elizabeth D.

Publication type:

Article

Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10966-8

By:

Birtley, James R.;
Alomary, Mohammad;
Zanini, Elisa;
Antony, Jane;
Maben, Zachary;
Weaver, Grant C.;
Von Arx, Claudia;
Mura, Manuela;
Marinho, Aline T.;
Lu, Haonan;
Morecroft, Eloise V. N.;
Karali, Evdoxia;
Chayen, Naomi E.;
Tate, Edward W.;
Jurewicz, Mollie;
Stern, Lawrence J.;
Recchi, Chiara;
Gabra, Hani

Publication type:

Article

EFFECTS OF MUTAGENETIC SUBSTITUTION OF PROLINES ON THE RATE OF DEPROTONATION and REPROTONATION OF THE SCHIFF BASE DURING THE PHOTOCYCLE OF BACTERIORHODOPSIN.

Published in:

Photochemistry & Photobiology, 1993, v. 57, p. 1027, doi. 10.1111/j.1751-1097.1993.tb02966.x

By:

Zhang, Yi N.;
El-Sayed, Mostafa A.;
Stern, Lawrence J.;
Marti, Thomas;
Mogi, Tatushi;
Khorana, H. Gobind

Publication type:

Article