Works by Sievers, Philipp

Results: 76
    1
    2

    Prediction of WHO grade and methylation class of aggressive meningiomas: Extraction of diagnostic information from infrared spectroscopic data.

    Published in:
    Neuro-Oncology Advances, 2024, v. 6, n. 1, p. 1, doi. 10.1093/noajnl/vdae082
    By:
    • Galli, Roberta;
    • Lehner, Franz;
    • Richter, Sven;
    • Kirsche, Katrin;
    • Meinhardt, Matthias;
    • Juratli, Tareq A;
    • Temme, Achim;
    • Kirsch, Matthias;
    • Warta, Rolf;
    • Herold-Mende, Christel;
    • Ricklefs, Franz L;
    • Lamszus, Katrin;
    • Sievers, Philipp;
    • Sahm, Felix;
    • Eyüpoglu, Ilker Y;
    • Uckermann, Ortrud
    Publication type:
    Article
    3

    Analysis of recurrence probability following radiotherapy in patients with CNS WHO grade 2 meningioma using integrated molecular-morphologic classification.

    Published in:
    Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad059
    By:
    • Deng, Maximilian Y;
    • Hinz, Felix;
    • Maas, Sybren L N;
    • Anil, Günes;
    • Sievers, Philipp;
    • Conde-Lopez, Cristina;
    • Lischalk, Jonathan;
    • Rauh, Sophie;
    • Eichkorn, Tanja;
    • Regnery, Sebastian;
    • Bauer, Lukas;
    • Held, Thomas;
    • Meixner, Eva;
    • Lang, Kristin;
    • Hörner-Rieber, Juliane;
    • Herfarth, Klaus;
    • Jones, David;
    • Pfister, Stefan M;
    • Jungk, Christine;
    • Unterberg, Andreas
    Publication type:
    Article
    4

    Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature.

    Published in:
    NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00372-1
    By:
    • Sievers, Philipp;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Abdullaev, Zied;
    • Donson, Andrew M.;
    • Lake, Jessica A.;
    • Friedel, Dennis;
    • Scheie, David;
    • Tynninen, Olli;
    • Rauramaa, Tuomas;
    • Vepsäläinen, Kaisa L.;
    • Samuel, David;
    • Chapman, Rebecca;
    • Grundy, Richard G.;
    • Pajtler, Kristian W.;
    • Tauziède-Espariat, Arnault;
    • Métais, Alice;
    • Varlet, Pascale;
    • Snuderl, Matija;
    • Jacques, Thomas S.
    Publication type:
    Article
    5

    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45067-8
    By:
    • Hai, Ling;
    • Hoffmann, Dirk C.;
    • Wagener, Robin J.;
    • Azorin, Daniel D.;
    • Hausmann, David;
    • Xie, Ruifan;
    • Huppertz, Magnus-Carsten;
    • Hiblot, Julien;
    • Sievers, Philipp;
    • Heuer, Sophie;
    • Ito, Jakob;
    • Cebulla, Gina;
    • Kourtesakis, Alexandros;
    • Kaulen, Leon D.;
    • Ratliff, Miriam;
    • Mandelbaum, Henriette;
    • Jung, Erik;
    • Jabali, Ammar;
    • Horschitz, Sandra;
    • Ernst, Kati J.
    Publication type:
    Article
    6

    CIC/ATXN1‐rearranged tumors in the central nervous system are mainly represented by sarcomas: A comprehensive clinicopathological and epigenetic series.

    Published in:
    Brain Pathology, 2025, v. 35, n. 2, p. 1, doi. 10.1111/bpa.13303
    By:
    • Tauziède‐Espariat, Arnault;
    • Ebrahimi, Azadeh;
    • Boddaert, Nathalie;
    • Pietsch, Torsten;
    • Grajkowska, Wieslawa;
    • Blau, Tobias;
    • Koch, Arend;
    • Sievers, Philipp;
    • Guillemot, Delphine;
    • Pierron, Gaëlle;
    • Uro‐Coste, Emmanuelle;
    • Nicaise, Yvan;
    • Siegfried, Aurore;
    • Gilles, Adam;
    • Bielle, Franck;
    • Mokhtari, Karima;
    • Cazals‐Hatem, Dominique;
    • Iakovlev, Gueorgui;
    • Lhermitte, Benoît;
    • Entz‐Werle, Natacha
    Publication type:
    Article
    7

    A comprehensive histomolecular characterization of meningioangiomatosis: Further evidence for a precursor neoplastic lesion.

    Published in:
    Brain Pathology, 2024, v. 34, n. 6, p. 1, doi. 10.1111/bpa.13259
    By:
    • Tauziède‐Espariat, Arnault;
    • Masliah‐Planchon, Julien;
    • Sievers, Philipp;
    • Sahm, Felix;
    • Dangouloff‐Ros, Volodia;
    • Boddaert, Nathalie;
    • Hasty, Lauren;
    • Aboubakr, Oumaima;
    • Métais, Alice;
    • Chrétien, Fabrice;
    • Roux, Alexandre;
    • Pallud, Johan;
    • Blauwblomme, Thomas;
    • Beccaria, Kévin;
    • Bourdeaut, Franck;
    • Puget, Stéphanie;
    • Varlet, Pascale
    Publication type:
    Article
    8

    A comprehensive analysis of infantile central nervous system tumors to improve distinctive criteria for infant‐type hemispheric glioma versus desmoplastic infantile ganglioglioma/astrocytoma.

    Published in:
    Brain Pathology, 2023, v. 33, n. 5, p. 1, doi. 10.1111/bpa.13182
    By:
    • Tauziède‐Espariat, Arnault;
    • Beccaria, Kévin;
    • Dangouloff‐Ros, Volodia;
    • Sievers, Philipp;
    • Meurgey, Alexandra;
    • Pissaloux, Daniel;
    • Appay, Romain;
    • Saffroy, Raphaël;
    • Grill, Jacques;
    • Mariet, Cassandra;
    • Bourdeaut, Franck;
    • Hasty, Lauren;
    • Métais, Alice;
    • Chrétien, Fabrice;
    • Blauwblomme, Thomas;
    • Puget, Stéphanie;
    • Boddaert, Nathalie;
    • Varlet, Pascale
    Publication type:
    Article
    9
    10

    Deciphering the genetic and epigenetic landscape of pediatric bithalamic tumors.

    Published in:
    Brain Pathology, 2022, v. 32, n. 3, p. 1, doi. 10.1111/bpa.13039
    By:
    • Tauziède‐Espariat, Arnault;
    • Debily, Marie‐Anne;
    • Castel, David;
    • Grill, Jacques;
    • Puget, Stéphanie;
    • Roux, Alexandre;
    • Saffroy, Raphaël;
    • Gauchotte, Guillaume;
    • Wahler, Ellen;
    • Hasty, Lauren;
    • Chrétien, Fabrice;
    • Lechapt, Emmanuèle;
    • Dangouloff‐Ros, Volodia;
    • Boddaert, Nathalie;
    • Sievers, Philipp;
    • Varlet, Pascale
    Publication type:
    Article
    11

    An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB‐fused broadening the spectrum of tumor entities in comparison with their soft tissue counterparts.

    Published in:
    Brain Pathology, 2022, v. 32, n. 1, p. 1, doi. 10.1111/bpa.13010
    By:
    • Tauziède‐Espariat, Arnault;
    • Sievers, Philipp;
    • Larousserie, Frédérique;
    • Benzakoun, Joseph;
    • Guillemot, Delphine;
    • Pierron, Gaëlle;
    • Duchesne, Mathilde;
    • Uro‐Coste, Emmanuelle;
    • Roux, Alexandre;
    • Vasiljevic, Alexandre;
    • Fenouil, Tanguy;
    • Meyronet, David;
    • Mokhtari, Karima;
    • Polivka, Marc;
    • Rousseau, Audrey;
    • Bost‐Bezeaud, Frédérique;
    • Akoury, Samir;
    • Pallud, Johan;
    • Benevello, Chiara;
    • Hasty, Lauren
    Publication type:
    Article
    12

    Correlation between natural history and multi-omics profiling of meningiomas in NF2-related schwannomatosis suggests role of methylation group and immune microenvironment in tumor growth rate.

    Published in:
    Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02791-1
    By:
    • Teranishi, Yu;
    • Yurchenko, Andrey;
    • Tran, Suzanne;
    • Sievers, Philipp;
    • Rajabi, Fatemeh;
    • Ruchith, Singhabahu;
    • Abi-Jaoude, Samiya;
    • Blouin, Antoine;
    • Bielle, Franck;
    • Cazals-Hatem, Dominique;
    • Sahm, Felix;
    • Nikolaev, Sergey;
    • Kalamarides, Michel;
    • Peyre, Matthieu
    Publication type:
    Article
    13
    14

    Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations.

    Published in:
    Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02766-2
    By:
    • Sievers, Philipp;
    • Bielle, Franck;
    • Göbel, Kirsten;
    • Schrimpf, Daniel;
    • Nichelli, Lucia;
    • Mathon, Bertrand;
    • Appay, Romain;
    • Boldt, Henning B.;
    • Dohmen, Hildegard;
    • Selignow, Carmen;
    • Acker, Till;
    • Vicha, Ales;
    • Martinetto, Horacio;
    • Schweizer, Leonille;
    • Schüller, Ulrich;
    • Brandner, Sebastian;
    • Wesseling, Pieter;
    • Schmid, Simone;
    • Capper, David;
    • Abdullaev, Zied
    Publication type:
    Article
    15
    16

    PLAG1 fusions extend the spectrum of PLAG(L)-altered CNS tumors.

    Published in:
    Acta Neuropathologica, 2023, v. 146, n. 6, p. 841, doi. 10.1007/s00401-023-02643-4
    By:
    • Tauziède-Espariat, Arnault;
    • Siegfried, Aurore;
    • Nicaise, Yvan;
    • Dghayem, Delphine;
    • Laprie, Anne;
    • Lubrano, Vincent;
    • Richard, Pomone;
    • Gauchotte, Guillaume;
    • Malczuk, Joséphine;
    • Klein, Olivier;
    • Hasty, Lauren;
    • Métais, Alice;
    • Chrétien, Fabrice;
    • Dangouloff-Ros, Volodia;
    • Boddaert, Nathalie;
    • Sahm, Felix;
    • Sievers, Philipp;
    • Varlet, Pascale;
    • Uro-Coste, Emmanuelle
    Publication type:
    Article
    17

    Independent prognostic impact of DNA methylation class and chromosome 1p loss in WHO grade 2 and 3 meningioma undergoing adjuvant high-dose radiotherapy: comprehensive molecular analysis of EORTC 22042–26042.

    Published in:
    Acta Neuropathologica, 2023, v. 146, n. 6, p. 837, doi. 10.1007/s00401-023-02642-5
    By:
    • Maas, Sybren L. N.;
    • Sievers, Philipp;
    • Weber, Damien C.;
    • Weller, Michael;
    • van den Bent, Martin J.;
    • Mair, Maximilian J.;
    • Kros, Johan M.;
    • Carparrotti, Fransesca;
    • von Deimling, Andreas;
    • Salvador, Villà Freixa;
    • Peerdeman, Saskia Marguerite;
    • Casas-Martin, Jose;
    • Gorlia, Thierry;
    • Sahm, Felix;
    • Preusser, Matthias
    Publication type:
    Article
    18

    Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.

    Published in:
    Acta Neuropathologica, 2023, v. 146, n. 6, p. 853, doi. 10.1007/s00401-023-02638-1
    By:
    • Rahmanzade, Ramin;
    • Pfaff, Elke;
    • Banan, Rouzbeh;
    • Sievers, Philipp;
    • Suwala, Abigail K.;
    • Hinz, Felix;
    • Bogumil, Henri;
    • Cherkezov, Asan;
    • Kaan, Aras Fuat;
    • Schrimpf, Daniel;
    • Friedel, Dennis;
    • Göbel, Kirsten;
    • Keller, Felix;
    • Saenz-Sardà, Xavier;
    • Lossos, Alexander;
    • Sill, Martin;
    • Witt, Olaf;
    • Sakowitz, Oliver W.;
    • Korshunov, Andrey;
    • Reuss, David E.
    Publication type:
    Article
    19
    20

    Correction to: Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 4, p. 511, doi. 10.1007/s00401-023-02538-4
    By:
    • Keck, Michaela-Kristina;
    • Sill, Martin;
    • Wittmann, Andrea;
    • Joshi, Piyush;
    • Stichel, Damian;
    • Beck, Pengbo;
    • Okonechnikow, Konstantin;
    • Sievers, Philipp;
    • Wefers, Annika K.;
    • Roncaroli, Federico;
    • Avula, Shivaram;
    • McCabe, Martin G.;
    • Hayden, James T.;
    • Wesseling, Pieter;
    • Øra, Ingrid;
    • Nistér, Monica;
    • Kranendonk, Mariëtte E. G.;
    • Tops, Bastiaan B. J.;
    • Zapotocky, Michal;
    • Zamecnik, Josef
    Publication type:
    Article
    21

    Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.

    Published in:
    Acta Neuropathologica, 2023, v. 145, n. 1, p. 49, doi. 10.1007/s00401-022-02516-2
    By:
    • Keck, Michaela-Kristina;
    • Sill, Martin;
    • Wittmann, Andrea;
    • Joshi, Piyush;
    • Stichel, Damian;
    • Beck, Pengbo;
    • Okonechnikow, Konstantin;
    • Sievers, Philipp;
    • Wefers, Annika K.;
    • Roncaroli, Federico;
    • Avula, Shivaram;
    • McCabe, Martin G.;
    • Hayden, James T.;
    • Wesseling, Pieter;
    • Øra, Ingrid;
    • Nistér, Monica;
    • Kranendonk, Mariëtte E. G.;
    • Tops, Bastiaan B. J.;
    • Zapotocky, Michal;
    • Zamecnik, Josef
    Publication type:
    Article
    22

    Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases.

    Published in:
    Acta Neuropathologica, 2022, v. 144, n. 5, p. 1049, doi. 10.1007/s00401-022-02492-7
    By:
    • Sievers, Philipp;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Friedel, Dennis;
    • Sturm, Dominik;
    • Gardberg, Maria;
    • Kurian, Kathreena M.;
    • Krskova, Lenka;
    • Vicha, Ales;
    • Schaller, Tina;
    • Hagel, Christian;
    • Abdullaev, Zied;
    • Aldape, Kenneth;
    • Jacques, Thomas S.;
    • Korshunov, Andrey;
    • Wick, Wolfgang;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Jones, David T. W.;
    • Sahm, Felix
    Publication type:
    Article
    23
    24

    Rapid-CNS<sup>2</sup>: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study.

    Published in:
    Acta Neuropathologica, 2022, v. 143, n. 5, p. 609, doi. 10.1007/s00401-022-02415-6
    By:
    • Patel, Areeba;
    • Dogan, Helin;
    • Payne, Alexander;
    • Krause, Elena;
    • Sievers, Philipp;
    • Schoebe, Natalie;
    • Schrimpf, Daniel;
    • Blume, Christina;
    • Stichel, Damian;
    • Holmes, Nadine;
    • Euskirchen, Philipp;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Rosenstiel-Goidts, Violaine;
    • Ratliff, Miriam;
    • Etminan, Nima;
    • Unterberg, Andreas;
    • Dieterich, Christoph;
    • Herold-Mende, Christel;
    • Pfister, Stefan M.
    Publication type:
    Article
    25

    GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 6, p. 1065, doi. 10.1007/s00401-021-02369-1
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Sturm, Dominik;
    • Selt, Florian;
    • Ecker, Jonas;
    • Kazdal, Daniel;
    • Miele, Evelina;
    • Kranendonk, Mariëtte E. G.;
    • Tops, Bastiaan B. J.;
    • Kohlhof-Meinecke, Patricia;
    • Beschorner, Rudi;
    • Kramm, Christof M.;
    • Hasselblatt, Martin;
    • Reifenberger, Guido;
    • Capper, David;
    • Wesseling, Pieter;
    • Stenzinger, Albrecht;
    • Milde, Till
    Publication type:
    Article
    26

    Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 827, doi. 10.1007/s00401-021-02356-6
    By:
    • Sievers, Philipp;
    • Henneken, Sophie C.;
    • Blume, Christina;
    • Sill, Martin;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Okonechnikov, Konstantin;
    • Reuss, David E.;
    • Benzel, Julia;
    • Maaß, Kendra K.;
    • Kool, Marcel;
    • Sturm, Dominik;
    • Zheng, Tuyu;
    • Ghasemi, David R.;
    • Kohlhof-Meinecke, Patricia;
    • Cruz, Ofelia;
    • Suñol, Mariona;
    • Lavarino, Cinzia;
    • Ruf, Viktoria;
    • Boldt, Henning B.
    Publication type:
    Article
    27

    PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 841, doi. 10.1007/s00401-021-02354-8
    By:
    • Alhalabi, Karam T.;
    • Stichel, Damian;
    • Sievers, Philipp;
    • Peterziel, Heike;
    • Sommerkamp, Alexander C.;
    • Sturm, Dominik;
    • Wittmann, Andrea;
    • Sill, Martin;
    • Jäger, Natalie;
    • Beck, Pengbo;
    • Pajtler, Kristian W.;
    • Snuderl, Matija;
    • Jour, George;
    • Delorenzo, Michael;
    • Martin, Allison M.;
    • Levy, Adam;
    • Dalvi, Nagma;
    • Hansford, Jordan R.;
    • Gottardo, Nicholas G.;
    • Uro-Coste, Emmanuelle
    Publication type:
    Article
    28

    Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 5, p. 873, doi. 10.1007/s00401-021-02351-x
    By:
    • Kirches, Elmar;
    • Sahm, Felix;
    • Korshunov, Andrey;
    • Bluecher, Christina;
    • Waldt, Natalie;
    • Kropf, Siegfried;
    • Schrimpf, Daniel;
    • Sievers, Philipp;
    • Stichel, Damian;
    • Schüller, Ulrich;
    • Schittenhelm, Jens;
    • Riemenschneider, Markus J.;
    • Karajannis, Matthias A.;
    • Perry, Arie;
    • Pietsch, Torsten;
    • Boekhoff, Svenja;
    • Capper, David;
    • Beck, Katja;
    • Paramasivam, Nagarajan;
    • Schlesner, Matthias
    Publication type:
    Article
    29

    Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.

    Published in:
    Acta Neuropathologica, 2021, v. 142, n. 1, p. 179, doi. 10.1007/s00401-021-02302-6
    By:
    • Suwala, Abigail K.;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Maas, Sybren L. N.;
    • Sill, Martin;
    • Dohmen, Hildegard;
    • Banan, Rouzbeh;
    • Reinhardt, Annekathrin;
    • Sievers, Philipp;
    • Hinz, Felix;
    • Blattner-Johnson, Mirjam;
    • Hartmann, Christian;
    • Schweizer, Leonille;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther;
    • Schittenhelm, Jens;
    • Wood, Matthew D.;
    • Chotard, Guillaume;
    • Bjergvig, Rolf;
    • Das, Anirban
    Publication type:
    Article
    30

    Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.

    Published in:
    Acta Neuropathologica, 2021, v. 141, n. 2, p. 281, doi. 10.1007/s00401-020-02247-2
    By:
    • Sievers, Philipp;
    • Sill, Martin;
    • Blume, Christina;
    • Tauziede-Espariat, Arnault;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David E.;
    • Dogan, Helin;
    • Hartmann, Christian;
    • Mawrin, Christian;
    • Hasselblatt, Martin;
    • Stummer, Walter;
    • Schick, Uta;
    • Hench, Jürgen;
    • Frank, Stephan;
    • Ketter, Ralf;
    • Schweizer, Leonille;
    • Schittenhelm, Jens;
    • Puget, Stéphanie;
    • Brandner, Sebastian
    Publication type:
    Article
    31

    CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.

    Published in:
    Acta Neuropathologica, 2020, v. 140, n. 3, p. 409, doi. 10.1007/s00401-020-02188-w
    By:
    • Sievers, Philipp;
    • Hielscher, Thomas;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David E.;
    • Berghoff, Anna S.;
    • Neidert, Marian C.;
    • Wirsching, Hans-Georg;
    • Mawrin, Christian;
    • Ketter, Ralf;
    • Paulus, Werner;
    • Reifenberger, Guido;
    • Lamszus, Katrin;
    • Westphal, Manfred;
    • Etminan, Nima;
    • Ratliff, Miriam;
    • Herold-Mende, Christel;
    • Pfister, Stefan M.;
    • Jones, David T. W.;
    • Weller, Michael
    Publication type:
    Article
    32

    Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.

    Published in:
    Acta Neuropathologica, 2020, v. 139, n. 3, p. 583, doi. 10.1007/s00401-019-02102-z
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Ghasemi, David R.;
    • Pajtler, Kristian W.;
    • Antonelli, Manila;
    • Donofrio, Vittoria;
    • Mastronuzzi, Angela;
    • Rossi, Sabrina;
    • Camassei, Francesca Diomedi;
    • Buccoliero, Anna Maria;
    • Haberler, Christine;
    • Slavc, Irene;
    • Dahiya, Sonika;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen
    Publication type:
    Article
    33
    34

    YAP1-fusions in pediatric NF2-wildtype meningioma.

    Published in:
    2020
    By:
    • Sievers, Philipp;
    • Chiang, Jason;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Paramasivam, Nagarajan;
    • Sill, Martin;
    • Gayden, Tenzin;
    • Casalini, Belen;
    • Reuss, David E.;
    • Dalton, James;
    • Pajtler, Kristian W.;
    • Hänggi, Daniel;
    • Herold-Mende, Christel;
    • Rushing, Elisabeth;
    • Korshunov, Andrey;
    • Mawrin, Christian;
    • Weller, Michael;
    • Schlesner, Matthias;
    • Wick, Wolfgang;
    • Jabado, Nada
    Publication type:
    Letter
    35

    Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.

    Published in:
    Acta Neuropathologica, 2020, v. 139, n. 1, p. 193, doi. 10.1007/s00401-019-02078-w
    By:
    • Wefers, Annika K.;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Coras, Roland;
    • Pages, Mélanie;
    • Tauziède-Espariat, Arnault;
    • Varlet, Pascale;
    • Schwarz, Daniel;
    • Söylemezoglu, Figen;
    • Pohl, Ute;
    • Pimentel, José;
    • Meyer, Jochen;
    • Hewer, Ekkehard;
    • Japp, Anna;
    • Joshi, Abhijit;
    • Reuss, David E.;
    • Reinhardt, Annekathrin;
    • Sievers, Philipp;
    • Casalini, M. Belén;
    • Ebrahimi, Azadeh
    Publication type:
    Article
    36

    Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 5, p. 827, doi. 10.1007/s00401-019-02039-3
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Casalini, Belén;
    • Meyer, Jochen;
    • Wefers, Annika K.;
    • Sievers, Philipp;
    • Korshunov, Andrey;
    • Koelsche, Christian;
    • Reuss, David E.;
    • Reinhardt, Annekathrin;
    • Ebrahimi, Azadeh;
    • Fernández-Klett, Francisco;
    • Kessler, Tobias;
    • Sturm, Dominik;
    • Ecker, Jonas;
    • Milde, Till;
    • Herold-Mende, Christel;
    • Witt, Olaf;
    • Pfister, Stefan M.;
    • Wick, Wolfgang
    Publication type:
    Article
    37

    Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 3, p. 497, doi. 10.1007/s00401-019-02038-4
    By:
    • Sievers, Philipp;
    • Appay, Romain;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David E.;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Coras, Roland;
    • Ruf, Viktoria C.;
    • Schmid, Simone;
    • de Stricker, Karin;
    • Boldt, Henning B.;
    • Kristensen, Bjarne Winther;
    • Petersen, Jeanette Krogh;
    • Ulhøi, Benedicte P.;
    • Gardberg, Maria;
    • Aronica, Eleonora;
    • Hasselblatt, Martin;
    • Brück, Wolfgang;
    • Bielle, Franck
    Publication type:
    Article
    38

    Molecular progression of SHH-activated medulloblastomas.

    Published in:
    2019
    By:
    • Korshunov, Andrey;
    • Okonechnikov, Konstantin;
    • Sahm, Felix;
    • Ryzhova, Marina;
    • Stichel, Damian;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Schrimpf, Daniel;
    • Zheludkova, Olga;
    • Golanov, Andrey;
    • Lichter, Peter;
    • Jones, David T. W.;
    • Pfister, Stefan M.;
    • von Deimling, Andreas;
    • Kool, Marcel
    Publication type:
    Letter
    39

    Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 2, p. 295, doi. 10.1007/s00401-019-02008-w
    By:
    • Paramasivam, Nagarajan;
    • Hübschmann, Daniel;
    • Toprak, Umut H;
    • Ishaque, Naveed;
    • Neidert, Marian;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David;
    • Sievers, Philipp;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Jones, David T. W.;
    • Gu, Zuguang;
    • Werner, Johannes;
    • Uhrig, Sebastian;
    • Wirsching, Hans-Georg;
    • Schick, Matthias;
    • Bewerunge-Hudler, Melanie;
    • Beck, Katja;
    • Brehmer, Stephanie
    Publication type:
    Article
    40

    Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 6, p. 1003, doi. 10.1007/s00401-019-01981-6
    By:
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Casalini, Belen;
    • Sievers, Philipp;
    • Meyer, Jochen;
    • Sahm, Felix;
    • von Deimling, Andreas;
    • Korshunov, Andrey;
    • Jones, David T. W.;
    • Okonechnikov, Konstantin;
    • Kool, Marcel;
    • Pfister, Stefan M.;
    • Lichter, Peter;
    • Ryzhova, Marina;
    • Zheludkova, Olga;
    • Golanov, Andrey
    Publication type:
    Article
    41

    Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.

    Published in:
    Acta Neuropathologica, 2019, v. 137, n. 5, p. 837, doi. 10.1007/s00401-019-01969-2
    By:
    • Hou, Yanghao;
    • Pinheiro, Jorge;
    • Sahm, Felix;
    • Reuss, David E.;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Casalini, Belén;
    • Koelsche, Christian;
    • Sievers, Philipp;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Ebrahimi, Azadeh;
    • Fernández-Klett, Francisco;
    • Pusch, Stefan;
    • Meier, Jochen;
    • Schweizer, Leonille;
    • Paulus, Werner;
    • Prinz, Marco;
    • Hartmann, Christian;
    • Plate, Karl H.
    Publication type:
    Article
    42

    Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 6, p. 975, doi. 10.1007/s00401-018-1924-x
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Hielscher, Thomas;
    • Schrimpf, Daniel;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Reuss, David;
    • Jones, David T. W.;
    • Bewerunge-Hudler, Melanie;
    • Hartmann, Christian;
    • Baumgarten, Peter;
    • Wirsching, Hans-Georg;
    • Winther-Kristensen, Bjarne;
    • Brokinkel, Benjamin;
    • Ketter, Ralf;
    • Idoate Gastearena, Miguel Angel;
    • Lamszus, Katrin;
    • Seiz-Rosenhagen, Marcel;
    • Mawrin, Christian;
    • Harter, Patrick N.
    Publication type:
    Article
    43

    FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 293, doi. 10.1007/s00401-018-1882-3
    By:
    • Sievers, Philipp;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Sahm, Felix;
    • Koelsche, Christian;
    • Reuss, David E.;
    • Wefers, Annika K.;
    • Reinhardt, Annekathrin;
    • Huang, Kristin;
    • Ebrahimi, Azadeh;
    • Hou, Yanghao;
    • Pajtler, Kristian W.;
    • Pfister, Stefan M.;
    • Hasselblatt, Martin;
    • Stummer, Walter;
    • Schick, Uta;
    • Hartmann, Christian;
    • Hagel, Christian;
    • Staszewski, Ori;
    • Reifenberger, Guido
    Publication type:
    Article
    44

    Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 2, p. 181, doi. 10.1007/s00401-018-1879-y
    By:
    • Capper, David;
    • Stichel, Damian;
    • Sahm, Felix;
    • Jones, David T. W.;
    • Schrimpf, Daniel;
    • Sill, Martin;
    • Schmid, Simone;
    • Hovestadt, Volker;
    • Reuss, David E.;
    • Koelsche, Christian;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Huang, Kristin;
    • Sievers, Philipp;
    • Ebrahimi, Azadeh;
    • Schöler, Anne;
    • Teichmann, Daniel;
    • Koch, Arend;
    • Hänggi, Daniel;
    • Unterberg, Andreas
    Publication type:
    Article
    45

    Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.

    Published in:
    Acta Neuropathologica, 2018, v. 136, n. 1, p. 153, doi. 10.1007/s00401-018-1849-4
    By:
    • Shirahata, Mitsuaki;
    • Ono, Takahiro;
    • Stichel, Damian;
    • Schrimpf, Daniel;
    • Reuss, David E.;
    • Sahm, Felix;
    • Koelsche, Christian;
    • Wefers, Annika;
    • Reinhardt, Annekathrin;
    • Huang, Kristin;
    • Sievers, Philipp;
    • Shimizu, Hiroaki;
    • Nanjo, Hiroshi;
    • Kobayashi, Yusuke;
    • Miyake, Yohei;
    • Suzuki, Tomonari;
    • Adachi, Jun-ichi;
    • Mishima, Kazuhiko;
    • Sasaki, Atsushi;
    • Nishikawa, Ryo
    Publication type:
    Article
    46

    Efficacy and toxicity of bimodal radiotherapy in WHO grade 2 meningiomas following subtotal resection with carbon ion boost: Prospective phase 2 MARCIE trial.

    Published in:
    Neuro-Oncology, 2024, v. 26, n. 4, p. 701, doi. 10.1093/neuonc/noad244
    By:
    • Deng, Maximilian Y;
    • Maas, Sybren L N;
    • Hinz, Felix;
    • Karger, Christian P;
    • Sievers, Philipp;
    • Eichkorn, Tanja;
    • Meixner, Eva;
    • Hoegen-Sassmannshausen, Philipp;
    • Hörner-Rieber, Juliane;
    • Lischalk, Jonathan W;
    • Seidensaal, Katharina;
    • Bernhardt, Denise;
    • Jungk, Christine;
    • Unterberg, Andreas;
    • Wick, Antje;
    • Wick, Wolfgang;
    • Deimling, Andreas von;
    • Sahm, Felix;
    • Combs, Stephanie;
    • Herfarth, Klaus
    Publication type:
    Article
    47

    LOGGIC Core BioClinical Data Bank: Added clinical value of RNA-Seq in an international molecular diagnostic registry for pediatric low-grade glioma patients.

    Published in:
    Neuro-Oncology, 2023, v. 25, n. 11, p. 2087, doi. 10.1093/neuonc/noad078
    By:
    • Hardin, Emily C;
    • Schmid, Simone;
    • Sommerkamp, Alexander;
    • Bodden, Carina;
    • Heipertz, Anna-Elisa;
    • Sievers, Philipp;
    • Wittmann, Andrea;
    • Milde, Till;
    • Pfister, Stefan M;
    • Deimling, Andreas von;
    • Horn, Svea;
    • Herz, Nina A;
    • Simon, Michèle;
    • Perera, Ashwyn A;
    • Azizi, Amedeo;
    • Cruz, Ofelia;
    • Curry, Sarah;
    • Damme, An Van;
    • Garami, Miklos;
    • Hargrave, Darren
    Publication type:
    Article
    48

    BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.

    Published in:
    Neuro-Oncology, 2023, v. 25, n. 4, p. 735, doi. 10.1093/neuonc/noac199
    By:
    • Selt, Florian;
    • Sigaud, Romain;
    • Valinciute, Gintvile;
    • Sievers, Philipp;
    • Zaman, Julia;
    • Alcon, Clara;
    • Schmid, Simone;
    • Peterziel, Heike;
    • Tsai, Jessica W;
    • Guiho, Romain;
    • Martínez-Barbera, Juan Pedro;
    • Pusch, Stefan;
    • Deng, Jing;
    • Zhai, Yifan;
    • Tilburg, Cornelis M van;
    • Schuhman, Martin U;
    • Damaty, Ahmed El;
    • Bandopadhayay, Pratiti;
    • Herold-Mende, Christel;
    • Deimling, Andreas von
    Publication type:
    Article
    49

    A case of glioneuronal tumour with ATRX alteration, kinase fusion and anaplastic features showing rapid ependymal and leptomeningeal dissemination.

    Published in:
    Neuropathology & Applied Neurobiology, 2024, v. 50, n. 4, p. 1, doi. 10.1111/nan.13001
    By:
    • Miele, Evelina;
    • Barresi, Sabina;
    • Colafati, Giovanna Stefania;
    • Pedace, Lucia;
    • Cardoni, Antonello;
    • Nardini, Claudia;
    • Tancredi, Chantal;
    • Patrizi, Sara;
    • Del Baldo, Giada;
    • Megaro, Giacomina;
    • Muccio, Carmine Franco;
    • Sievers, Philipp;
    • Alaggio, Rita;
    • Mastronuzzi, Angela;
    • Rossi, Sabrina;
    • Locatelli, Franco
    Publication type:
    Article
    50

    Rosette‐forming glioneuronal tumours are midline, FGFR1‐mutated tumours.

    Published in:
    Neuropathology & Applied Neurobiology, 2022, v. 48, n. 5, p. 1, doi. 10.1111/nan.12813
    By:
    • Appay, Romain;
    • Bielle, Franck;
    • Sievers, Philipp;
    • Barets, Doriane;
    • Fina, Frédéric;
    • Boutonnat, Jean;
    • Adam, Clovis;
    • Gauchotte, Guillaume;
    • Godfraind, Catherine;
    • Lhermitte, Benoît;
    • Maurage, Claude‐Alain;
    • Meyronet, David;
    • Mokhtari, Karima;
    • Rousseau, Audrey;
    • Tauziède‐Espariat, Arnault;
    • Tortel, Marie‐Claire;
    • Uro‐Coste, Emmanuelle;
    • Burel‐Vandenbos, Fanny;
    • Chotard, Guillaume;
    • Pesce, Florian
    Publication type:
    Article