Works by Rogelj, Boris

Results: 57

Overlapping Neuroimmune Mechanisms and Therapeutic Targets in Neurodegenerative Disorders.

Published in:

Biomedicines, 2023, v. 11, n. 10, p. 2793, doi. 10.3390/biomedicines11102793

By:

De Marchi, Fabiola;
Munitic, Ivana;
Vidatic, Lea;
Papić, Eliša;
Rački, Valentino;
Nimac, Jerneja;
Jurak, Igor;
Novotni, Gabriela;
Rogelj, Boris;
Vuletic, Vladimira;
Liscic, Rajka M.;
Cannon, Jason R.;
Buratti, Emanuele;
Mazzini, Letizia;
Hecimovic, Silva

Publication type:

Article

Emerging Trends in the Field of Inflammation and Proteinopathy in ALS/FTD Spectrum Disorder.

Published in:

Biomedicines, 2023, v. 11, n. 6, p. 1599, doi. 10.3390/biomedicines11061599

By:

De Marchi, Fabiola;
Franjkic, Toni;
Schito, Paride;
Russo, Tommaso;
Nimac, Jerneja;
Chami, Anna A.;
Mele, Angelica;
Vidatic, Lea;
Kriz, Jasna;
Julien, Jean-Pierre;
Apic, Gordana;
Russell, Robert B.;
Rogelj, Boris;
Cannon, Jason R.;
Baralle, Marco;
Agosta, Federica;
Hecimovic, Silva;
Mazzini, Letizia;
Buratti, Emanuele;
Munitic, Ivana

Publication type:

Article

An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline.

Published in:

Neuropathology, 2012, v. 32, n. 5, p. 505, doi. 10.1111/j.1440-1789.2011.01286.x

By:

Troakes, Claire;
Maekawa, Satomi;
Wijesekera, Lokesh;
Rogelj, Boris;
Siklós, László;
Bell, Christopher;
Smith, Bradley;
Newhouse, Stephen;
Vance, Caroline;
Johnson, Lauren;
Hortobágyi, Tibor;
Shatunov, Aleksey;
Al-Chalabi, Ammar;
Leigh, Nigel;
Shaw, Christopher E.;
King, Andrew;
Al-Sarraj, Safa

Publication type:

Article

The Role of c-Abl Tyrosine Kinase in Brain and Its Pathologies.

Published in:

Cells (2073-4409), 2023, v. 12, n. 16, p. 2041, doi. 10.3390/cells12162041

By:

Motaln, Helena;
Rogelj, Boris

Publication type:

Article

The Impact of ALS-Associated Genes hnRNPA1, MATR3, VCP and UBQLN2 on the Severity of TDP-43 Aggregation.

Published in:

Cells (2073-4409), 2020, v. 9, n. 8, p. 1791, doi. 10.3390/cells9081791

By:

Bajc Česnik, Ana;
Motaln, Helena;
Rogelj, Boris

Publication type:

Article

The Neurotropic Black Yeast Exophiala dermatitidis Induces Neurocytotoxicity in Neuroblastoma Cells and Progressive Cell Death.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 963, doi. 10.3390/cells9040963

By:

Lavrin, Teja;
Konte, Tilen;
Kostanjšek, Rok;
Sitar, Simona;
Sepčič, Kristina;
Prpar Mihevc, Sonja;
Žagar, Ema;
Župunski, Vera;
Lenassi, Metka;
Rogelj, Boris;
Gunde Cimerman, Nina

Publication type:

Article

The C9ORF72 expansion mutation is a common cause of ALS+/−FTD in Europe and has a single founder.

Published in:

European Journal of Human Genetics, 2013, v. 21, n. 1, p. 102, doi. 10.1038/ejhg.2012.98

By:

Smith, Bradley N;
Newhouse, Stephen;
Shatunov, Aleksey;
Vance, Caroline;
Topp, Simon;
Johnson, Lauren;
Miller, Jack;
Lee, Younbok;
Troakes, Claire;
Scott, Kirsten M;
Jones, Ashley;
Gray, Ian;
Wright, Jamie;
Hortobágyi, Tibor;
Al-Sarraj, Safa;
Rogelj, Boris;
Powell, John;
Lupton, Michelle;
Lovestone, Simon;
Sapp, Peter C

Publication type:

Article

Heterogeneous Nuclear Ribonucleoprotein E2 (hnRNP E2) Is a Component of TDP-43 Aggregates Specifically in the A and C Pathological Subtypes of Frontotemporal Lobar Degeneration.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00551

By:

Kattuah, Wejdan;
Rogelj, Boris;
King, Andrew;
Shaw, Christopher E.;
Hortobágyi, Tibor;
Troakes, Claire

Publication type:

Article

Heterogeneity in the cysteine protease inhibitor clitocypin gene family.

Published in:

Biological Chemistry, 2006, v. 387, n. 12, p. 1559, doi. 10.1515/BC.2006.194

By:

Sabotič, Jerica;
Gaser, Dominik;
Rogelj, Boris;
Gruden, Kristina;
Štrukelj, Borut;
Brzin, Jože

Publication type:

Article

The Effect of Different Types of Nanoparticles on FUS and TDP-43 Solubility and Subcellular Localization.

Published in:

Neurotoxicity Research, 2017, v. 32, n. 3, p. 325, doi. 10.1007/s12640-017-9734-9

By:

Lojk, Jasna;
Prpar Mihevc, Sonja;
Bregar, Vladimir;
Pavlin, Mojca;
Rogelj, Boris

Publication type:

Article

Postmortem chondrocyte viability in porcine articular cartilage: Influence of time, temperature, and burial under winter conditions.

Published in:

Journal of Forensic Sciences, 2024, v. 69, n. 3, p. 1094, doi. 10.1111/1556-4029.15503

By:

Cvetko, Marko;
Knific, Tanja;
Frangež, Robert;
Motaln, Helena;
Rogelj, Boris;
Alibegović, Armin;
Gombač, Mitja

Publication type:

Article

Cytoplasmic TDP-43 is involved in cell fate during stress recovery.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 2, p. 166, doi. 10.1093/hmg/ddab227

By:

Lee, Youn-Bok;
Scotter, Emma L;
Lee, Do-Young;
Troakes, Claire;
Mitchell, Jacqueline;
Rogelj, Boris;
Gallo, Jean-Marc;
Shaw, Christopher E

Publication type:

Article

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 3/4, p. 318, doi. 10.1093/hmg/ddaa181

By:

Lee, Youn-Bok;
Baskaran, Pranetha;
Gomez-Deza, Jorge;
Chen, Han-Jou;
Nishimura, Agnes L;
Smith, Bradley N;
Troakes, Claire;
Adachi, Yoshitsugu;
Stepto, Alan;
Petrucelli, Leonard;
Gallo, Jean-Marc;
Hirth, Frank;
Rogelj, Boris;
Guthrie, Sarah;
Shaw, Christopher E

Publication type:

Article

Evasin-displaying lactic acid bacteria bind different chemokines and neutralize CXCL8 production in Caco-2 cells.

Published in:

Microbial Biotechnology, 2017, v. 10, n. 6, p. 1732, doi. 10.1111/1751-7915.12781

By:

Škrlec, Katja;
Pucer Janež, Anja;
Rogelj, Boris;
Štrukelj, Borut;
Berlec, Aleš

Publication type:

Article

Analysis of TDP-43 and its binding partners in neurodegenerative diseases.

Published in:

2013

By:

Kattuah, Wejdan;
Troakes, Claire;
Hortobagyi, Tibor;
Rogelj, Boris;
Shaw, Christopher

Publication type:

Abstract

Expanded G4C2 repeats linked to C9ORF72 ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic.

Published in:

2013

By:

Youn-Bok Lee;
Han-Jou Chen;
Peres, João N.;
Gomez, Jorge;
Sardone, Valentina;
Nishimura, Agnes L.;
Scotter, Emma;
Vance, Caroline;
Štalekar, Maja;
Adachi, Yoshitsugu;
Troakes, Claire;
Miller, Jack;
Smith, Bradley;
Hirth, Frank;
Rogelj, Boris;
Houart, Corinne;
Shaw, Christopher E.

Publication type:

Abstract

Contextual fear conditioning regulates the expression of brain-specific small nucleolar RNAs in hippocampus.

Published in:

European Journal of Neuroscience, 2003, v. 18, n. 11, p. 3089, doi. 10.1111/j.1460-9568.2003.03026.x

By:

Rogelj, Boris;
Hartmann, Christoph E. A.;
Yeo, Christopher H.;
Hunt, Stephen P.;
Giese, K. Peter

Publication type:

Article

Astrocytes with TDP-43 inclusions exhibit reduced noradrenergic cAMP and Ca2+ signaling and dysregulated cell metabolism.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62864-5

By:

Velebit, Jelena;
Horvat, Anemari;
Smolič, Tina;
Prpar Mihevc, Sonja;
Rogelj, Boris;
Zorec, Robert;
Vardjan, Nina

Publication type:

Article

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

Published in:

Nature Neuroscience, 2011, v. 14, n. 4, p. 452, doi. 10.1038/nn.2778

By:

Tollervey, James R.;
Curk, Tomaž;
Rogelj, Boris;
Briese, Michael;
Cereda, Matteo;
Kayikci, Melis;
König, Julian;
Hortobágyi, Tibor;
Nishimura, Agnes L.;
Župunski, Vera;
Patani, Rickie;
Chandran, Siddharthan;
Rot, Gregor;
Zupan, Blaž;
Shaw, Christopher E.;
Ule, Jernej

Publication type:

Article

Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41511-3

By:

Malnar Črnigoj, Mirjana;
Čerček, Urša;
Yin, Xiaoke;
Ho, Manh Tin;
Repic Lampret, Barbka;
Neumann, Manuela;
Hermann, Andreas;
Rouleau, Guy;
Suter, Beat;
Mayr, Manuel;
Rogelj, Boris

Publication type:

Article

Differential Expression of Several miRNAs and the Host Genes AATK and DNM2 in Leukocytes of Sporadic ALS Patients.

Published in:

Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2018.00106

By:

Vrabec, Katarina;
Boštjančič, Emanuela;
Koritnik, Blaž;
Leonardis, Lea;
Dolenc Grošelj, Leja;
Zidar, Janez;
Rogelj, Boris;
Glavač, Damjan;
Ravnik-Glavač, Metka

Publication type:

Article

Varicella-zoster virus recapitulates its immune evasive behaviour in matured hiPSC-derived neurospheroids.

Published in:

Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1458967

By:

Govaerts, Jonas;
Van Breedam, Elise;
De Beuckeleer, Sarah;
Goethals, Charlotte;
D'Incal, Claudio Peter;
Di Stefano, Julia;
Van Calster, Siebe;
Buyle-Huybrecht, Tamariche;
Boeren, Marlies;
De Reu, Hans;
Paludan, Søren R.;
Thiry, Marc;
Lebrun, Marielle;
Sadzot-Delvaux, Catherine;
Motaln, Helena;
Rogelj, Boris;
Van Weyenbergh, Johan;
De Vos, Winnok H.;
Berghe, Wim Vanden;
Ogunjimi, Benson

Publication type:

Article

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion.

Published in:

Acta Neuropathologica, 2013, v. 125, n. 2, p. 273, doi. 10.1007/s00401-012-1043-z

By:

Mitchell, Jacqueline;
McGoldrick, Philip;
Vance, Caroline;
Hortobagyi, Tibor;
Sreedharan, Jemeen;
Rogelj, Boris;
Tudor, Elizabeth;
Smith, Bradley;
Klasen, Christian;
Miller, Christopher;
Cooper, Jonathan;
Greensmith, Linda;
Shaw, Christopher

Publication type:

Article

p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS.

Published in:

Acta Neuropathologica, 2011, v. 122, n. 6, p. 691, doi. 10.1007/s00401-011-0911-2

By:

Al-Sarraj, Safa;
King, Andrew;
Troakes, Claire;
Smith, Bradley;
Maekawa, Satomi;
Bodi, Istvan;
Rogelj, Boris;
Al-Chalabi, Ammar;
Hortobágyi, Tibor;
Shaw, Christopher

Publication type:

Article

Optineurin inclusions occur in a minority of TDP-43 positive ALS and FTLD-TDP cases and are rarely observed in other neurodegenerative disorders.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 4, p. 519, doi. 10.1007/s00401-011-0813-3

By:

Hortobágyi, Tibor;
Troakes, Claire;
Nishimura, Agnes L.;
Vance, Caroline;
van Swieten, John C.;
Seelaar, Harro;
King, Andrew;
Al-Sarraj, Safa;
Rogelj, Boris;
Shaw, Christopher E.

Publication type:

Article

Therapeutic Potential of Polyphenols in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Published in:

Antioxidants, 2021, v. 10, n. 8, p. 1328, doi. 10.3390/antiox10081328

By:

Novak, Valentina;
Rogelj, Boris;
Župunski, Vera

Publication type:

Article

Expression of the neuronal adaptor protein X11alpha protects against memory dysfunction in a transgenic mouse model of Alzheimer's disease.

Published in:

2010

By:

Mitchell JC;
Perkinton MS;
Yates DM;
Lau KF;
Rogelj B;
Miller CC;
McLoughlin DM;
Mitchell, Jacqueline C;
Perkinton, Michael S;
Yates, Darran M;
Lau, Kwok-Fai;
Rogelj, Boris;
Miller, Christopher C J;
McLoughlin, Declan M

Publication type:

journal article

Expression of the Neuronal Adaptor Protein X11α Protects Against Memory Dysfunction in a Transgenic Mouse Model of Alzheimer's Disease.

Published in:

Journal of Alzheimer's Disease, 2010, v. 20, n. 1, p. 31, doi. 10.3233/JAD-2010-1341

By:

Mitchell, Jacqueline C.;
Perkinton, Michael S.;
Yates, Darran M.;
Lau, Kwok-Fai;
Rogelj, Boris;
Miller, Christopher C. J.;
McLoughlin, Declan M.

Publication type:

Article

Neuroimmune characterization of optineurin insufficiency mouse model during ageing.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38875-3

By:

Mohovic, Nikolina;
Peradinovic, Josip;
Markovinovic, Andrea;
Cimbro, Raffaello;
Minic, Zeljka;
Dominovic, Marin;
Jakovac, Hrvoje;
Nimac, Jerneja;
Rogelj, Boris;
Munitic, Ivana

Publication type:

Article

Functional diversity of small nucleolar RNAs.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 4, p. 1627, doi. 10.1093/nar/gkz1140

By:

Bratkovič, Tomaž;
Božič, Janja;
Rogelj, Boris

Publication type:

Article

Abl kinase-mediated FUS Tyr526 phosphorylation alters nucleocytoplasmic FUS localization in FTLD-FUS.

Published in:

Brain: A Journal of Neurology, 2023, v. 146, n. 10, p. 4088, doi. 10.1093/brain/awad130

By:

Motaln, Helena;
Čerček, Urša;
Yamoah, Alfred;
Tripathi, Priyanka;
Aronica, Eleonora;
Goswami, Anand;
Rogelj, Boris

Publication type:

Article

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.

Published in:

2022

By:

Božič, Janja;
Motaln, Helena;
Janež, Anja Pucer;
Markič, Lara;
Tripathi, Priyanka;
Yamoah, Alfred;
Aronica, Eleonora;
Lee, Youn-Bok;
Heilig, Raphael;
Fischer, Roman;
Thompson, Andrew J;
Goswami, Anand;
Rogelj, Boris

Publication type:

journal article

Karyopherin abnormalities in neurodegenerative proteinopathies.

Published in:

2021

By:

Pasha, Terouz;
Zatorska, Anna;
Sharipov, Daulet;
Rogelj, Boris;
Hortobágyi, Tibor;
Hirth, Frank

Publication type:

journal article

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.

Published in:

2018

By:

Solomon, Daniel A;
Stepto, Alan;
Au, Wing Hei;
Adachi, Yoshitsugu;
Diaper, Danielle C;
Hall, Rachel;
Rekhi, Anjeet;
Boudi, Adel;
Tziortzouda, Paraskevi;
Lee, Youn-Bok;
Smith, Bradley;
Bridi, Jessika C;
Spinelli, Greta;
Dearlove, Jonah;
Humphrey, Dickon M;
Gallo, Jean-Marc;
Troakes, Claire;
Fanto, Manolis;
Soller, Matthias;
Rogelj, Boris

Publication type:

journal article

Nuclear trafficking in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.

Published in:

2017

By:

Mihevc, Sonja Prpar;
Darovic, Simona;
Kovanda, Anja;
Česnik, Ana Bajc;
Župunski, Vera;
Rogelj, Boris;
Prpar Mihevc, Sonja;
Bajc Česnik, Ana

Publication type:

journal article

A serum microRNA signature for amyotrophic lateral sclersosis reveals convergent RNA processing defects and identifies presymptomatic mutation carriers.

Published in:

2014

By:

Lee, Youn-Bok;
Rogelj, Boris;
Shaw, Christopher E

Publication type:

Journal Article

Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 6, p. 1763, doi. 10.1093/brain/awq111

By:

Nishimura, Agnes L.;
Župunski, Vera;
Troakes, Claire;
Kathe, Claudia;
Fratta, Pietro;
Howell, Michael;
Gallo, Jean-Marc;
Hortobágyi, Tibor;
Shaw, Christopher E.;
Rogelj, Boris

Publication type:

Article

Modelling FUS Mislocalisation in an In Vitro Model of Innervated Human Muscle.

Published in:

Journal of Molecular Neuroscience, 2017, v. 62, n. 3/4, p. 318, doi. 10.1007/s12031-017-0940-y

By:

Prpar Mihevc, Sonja;
Pavlin, Mojca;
Darovic, Simona;
Živin, Marko;
Podbregar, Matej;
Rogelj, Boris;
Mars, Tomaz

Publication type:

Article

Brain-specific small nucleolar RNAs.

Published in:

Journal of Molecular Neuroscience, 2006, v. 28, n. 2, p. 103, doi. 10.1385/JMN:28:2:103

By:

Rogelj, Boris

Publication type:

Article

MicroRNA in skeletal muscle development, growth, atrophy, and disease.

Published in:

Wiley Interdisciplinary Reviews: RNA, 2014, v. 5, n. 4, p. 509, doi. 10.1002/wrna.1227

By:

Kovanda, Anja;
Režen, Tadeja;
Rogelj, Boris

Publication type:

Article

Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091269

By:

Nishimura, Agnes L.;
Shum, Carole;
Scotter, Emma L.;
Abdelgany, Amr;
Sardone, Valentina;
Wright, Jamie;
Lee, Youn-Bok;
Chen, Han-Jou;
Bilican, Bilada;
Carrasco, Monica;
Maniatis, Tom;
Chandran, Siddharthan;
Rogelj, Boris;
Gallo, Jean-Marc;
Shaw, Christopher E.

Publication type:

Article

Biology and applications of small nucleolar RNAs.

Published in:

Cellular & Molecular Life Sciences, 2011, v. 68, n. 23, p. 3843, doi. 10.1007/s00018-011-0762-y

By:

Bratkovič, Tomaž;
Rogelj, Boris

Publication type:

Article

Innervation and electrical pulse stimulation — in vitro effects on human skeletal muscle cells.

Published in:

Applied Physiology, Nutrition & Metabolism, 2021, v. 46, n. 4, p. 299, doi. 10.1139/apnm-2019-0575

By:

Marš, Tomaz;
Miš, Katarina;
Meznarič, Marija;
Prpar Mihevc, Sonja;
Jan, Vid;
Haugen, Fred;
Rogelj, Boris;
Rustan, Arild C.;
Thoresen, G. Hege;
Pirkmajer, Sergej;
Nikolić, Nataša

Publication type:

Article

P1-382: Proteomic analysis of X11 interacting proteins

Published in:

2006

By:

Rogelj, Boris;
Mitchell, Jacqueline C.;
Lynham, Steven;
Byers, Helen L.;
Ward, Malcolm;
Miller, Christopher C.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-054: The neuronal X11α adaptor protein improves cognitive function of Tg2576 (APPswe) mice

Published in:

2006

By:

Mitchell, Jacqueline C.;
Rogelj, Boris;
Ariff, Belall;
Sluyter, Frans;
Stephenson, John;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-021: In vivo evidence for impaired LTP in Tg2576 (APPswe) mice

Published in:

2006

By:

McLoughlin, Declan M.;
Arrif, Belall;
Mitchell, Jaqcqueline C.;
Rogelj, Boris;
Miller, Christopher C.;
Stephenson, John

Publication type:

Abstract

P1-382: Proteomic analysis of X11 interacting proteins

Published in:

2006

By:

Rogelj, Boris;
Mitchell, Jacqueline C.;
Lynham, Steven;
Byers, Helen L.;
Ward, Malcolm;
Miller, Christopher C.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-054: The neuronal X11α adaptor protein improves cognitive function of Tg2576 (APPswe) mice

Published in:

2006

By:

Mitchell, Jacqueline C.;
Rogelj, Boris;
Ariff, Belall;
Sluyter, Frans;
Stephenson, John;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-021: In vivo evidence for impaired LTP in Tg2576 (APPswe) mice

Published in:

2006

By:

McLoughlin, Declan M.;
Arrif, Belall;
Mitchell, Jaqcqueline C.;
Rogelj, Boris;
Miller, Christopher C.;
Stephenson, John

Publication type:

Abstract

Intracellular Responses Triggered by Cold Atmospheric Plasma and Plasma-Activated Media in Cancer Cells.

Published in:

Molecules, 2021, v. 26, n. 5, p. 1336, doi. 10.3390/molecules26051336

By:

Motaln, Helena;
Recek, Nina;
Rogelj, Boris;
Vasiliev, Mikhail M.

Publication type:

Article