Works by Promislow, Daniel

Results: 87

Metabolome-wide association study of phenylalanine in plasma of common marmosets.

Published in:

Amino Acids, 2015, v. 47, n. 3, p. 589, doi. 10.1007/s00726-014-1893-x

By:

Go, Young-Mi;
Walker, Douglas;
Soltow, Quinlyn;
Uppal, Karan;
Wachtman, Lynn;
Strobel, Fredrick;
Pennell, Kurt;
Promislow, Daniel;
Jones, Dean

Publication type:

Article

Serotonin signaling modulates aging-associated metabolic network integrity in response to nutrient choice in Drosophila melanogaster.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02260-5

By:

Lyu, Yang;
Promislow, Daniel E. L.;
Pletcher, Scott D.

Publication type:

Article

Research to Promote Longevity and Health Span in Companion Dogs: A Pediatric Perspective.

Published in:

American Journal of Bioethics, 2018, v. 18, n. 10, p. 64, doi. 10.1080/15265161.2018.1513591

By:

Wilfond, Benjamin S.;
Porter, Kathryn M.;
Creevy, Kate E.;
Kaeberlein, Matt;
Promislow, Daniel

Publication type:

Article

Predictive Modeling of Alzheimer's and Parkinson's Disease Using Metabolomic and Lipidomic Profiles from Cerebrospinal Fluid.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 4, p. N.PAG, doi. 10.3390/metabo12040277

By:

Hwangbo, Nathan;
Zhang, Xinyu;
Raftery, Daniel;
Gu, Haiwei;
Hu, Shu-Ching;
Montine, Thomas J.;
Quinn, Joseph F.;
Chung, Kathryn A.;
Hiller, Amie L.;
Wang, Dongfang;
Fei, Qiang;
Bettcher, Lisa;
Zabetian, Cyrus P.;
Peskind, Elaine R.;
Li, Ge;
Promislow, Daniel E. L.;
Davis, Marie Y.;
Franks, Alexander

Publication type:

Article

Below-threshold mortality: implications for studies in evolution, ecology and demography.

Published in:

Journal of Evolutionary Biology, 1999, v. 12, n. 2, p. 314, doi. 10.1046/j.1420-9101.1999.00037.x

By:

Promislow;
Tatar;
Pletcher;
Carey;
Promislow, Daniel E. L.

Publication type:

Article

Host ecology shapes geographical variation for resistance to bacterial infection in Drosophila melanogaster.

Published in:

Journal of Animal Ecology, 2008, v. 77, n. 4, p. 768, doi. 10.1111/j.1365-2656.2008.01399.x

By:

Corby-Harris, Vanessa;
Promislow, Daniel E. L.

Publication type:

Article

Characterizing dog cognitive aging using spontaneous problem-solving measures: development of a battery of tests from the Dog Aging Project.

Published in:

GeroScience, 2025, v. 47, n. 1, p. 23, doi. 10.1007/s11357-024-01278-x

By:

Hargrave, Stephanie H.;
Bray, Emily E.;
McGrath, Stephanie;
Alexander, Gene E.;
Block, Theadora A.;
Chao, Naomi;
Darvas, Martin;
Douglas, Laura E. L. C.;
Galante, Janet;
Kennedy, Brenda S.;
Kusick, Breonna;
Moreno, Julie A.;
Promislow, Daniel E. L.;
Raichlen, David A.;
Switzer, Lorelei R.;
Tees, Lily;
Underwood Aguilar, Mikayla;
Urfer, Silvan R.;
Akey, Joshua M.;
Benton, Brooke

Publication type:

Article

The companion dog as a model for inflammaging: a cross-sectional pilot study.

Published in:

GeroScience, 2024, v. 46, n. 6, p. 5395, doi. 10.1007/s11357-024-01217-w

By:

Schmid, Sarah M.;
Hoffman, Jessica M.;
Prescott, Jena;
Ernst, Holley;
Promislow, Daniel E. L.;
Akey, Joshua M.;
Benton, Brooke;
Borenstein, Elhanan;
Castelhano, Marta G.;
Coleman, Amanda E.;
Creevy, Kate E.;
Crowder, Kyle;
Dunbar, Matthew D.;
Fajt, Virginia R.;
Fitzpatrick, Annette L.;
Jeffery, Unity;
Jonlin, Erica C.;
Kaeberlein, Matt;
Karlsson, Elinor K.;
Kerr, Kathleen F.

Publication type:

Article

Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan.

Published in:

GeroScience, 2023, v. 45, n. 4, p. 2161, doi. 10.1007/s11357-023-00796-4

By:

Phua, Cheryl Zi Jin;
Zhao, Xiaqing;
Turcios-Hernandez, Lesly;
McKernan, Morrigan;
Abyadeh, Morteza;
Ma, Siming;
Promislow, Daniel;
Kaeberlein, Matt;
Kaya, Alaattin

Publication type:

Article

Associations between physical activity and cognitive dysfunction in older companion dogs: results from the Dog Aging Project.

Published in:

GeroScience, 2023, v. 45, n. 2, p. 645, doi. 10.1007/s11357-022-00655-8

By:

Bray, Emily E.;
Raichlen, David A.;
Forsyth, Kiersten K.;
Promislow, Daniel E. L.;
Alexander, Gene E.;
MacLean, Evan L.;
Dog Aging Project Consortium;
Akey, Joshua M.;
Benton, Brooke;
Borenstein, Elhanan;
Castelhano, Marta G.;
Coleman, Amanda E.;
Creevy, Kate E.;
Crowder, Kyle;
Dunbar, Matthew D.;
Fajt, Virginia R.;
Fitzpatrick, Annette L.;
Jeffrey, Unity;
Jonlin, Erica C.;
Kaeberlein, Matt

Publication type:

Article

How size and genetic diversity shape lifespan across breeds of purebred dogs.

Published in:

GeroScience, 2023, v. 45, n. 2, p. 627, doi. 10.1007/s11357-022-00653-w

By:

Kraus, Cornelia;
Snyder-Mackler, Noah;
Promislow, Daniel E. L.

Publication type:

Article

A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response.

Published in:

GeroScience, 2022, v. 44, n. 4, p. 2195, doi. 10.1007/s11357-022-00557-9

By:

Hilsabeck, Tyler A. U.;
Liu-Bryan, Ru;
Guo, Tracy;
Wilson, Kenneth A.;
Bose, Neelanjan;
Raftery, Daniel;
Beck, Jennifer N.;
Lang, Sven;
Jin, Kelly;
Nelson, Christopher S.;
Oron, Tal;
Stoller, Marshall;
Promislow, Daniel;
Brem, Rachel B.;
Terkeltaub, Robert;
Kapahi, Pankaj

Publication type:

Article

Canine Cognitive Dysfunction (CCD) scores correlate with amyloid beta 42 levels in dog brain tissue.

Published in:

GeroScience, 2021, v. 43, n. 5, p. 2379, doi. 10.1007/s11357-021-00422-1

By:

Urfer, Silvan R.;
Darvas, Martin;
Czeibert, Kálmán;
Sándor, Sára;
Promislow, Daniel E. L.;
Creevy, Kate E.;
Kubinyi, Enikő;
Kaeberlein, Matt

Publication type:

Article

University of Washington Nathan Shock Center: innovation to advance aging research.

Published in:

GeroScience, 2021, v. 43, n. 5, p. 2161, doi. 10.1007/s11357-021-00413-2

By:

Kaeberlein, Matt;
Bitto, Alessandro;
Dunham, Maitreya J.;
Ladiges, Warren;
Lee, Su-In;
MacCoss, Michael J.;
Mendenhall, Alexander;
Promislow, Daniel E. L.;
Rabinovitch, Peter S.;
Villén, Judit;
Wang, Lu;
Wang, Yuliang;
Young, Jessica E.

Publication type:

Article

Wide‐ranging genetic variation in sensitivity to rapamycin in Drosophila melanogaster.

Published in:

Aging Cell, 2024, v. 23, n. 11, p. 1, doi. 10.1111/acel.14292

By:

Harrison, Benjamin R.;
Lee, Mitchell B.;
Zhang, Shufan;
Young, Bill;
Han, Kenneth;
Sukomol, Jiranut;
Paus, Vanessa;
Tran, Sarina;
Kim, David;
Fitchett, Hannah;
Pan, Yu‐Chen;
Tesfaye, Philmon;
Johnson, Alia W.;
Zhao, Xiaqing;
Djukovic, Danijel;
Raftery, Daniel;
Promislow, Daniel E. L.

Publication type:

Article

DNA methylation and chromatin accessibility predict age in the domestic dog.

Published in:

Aging Cell, 2024, v. 23, n. 4, p. 1, doi. 10.1111/acel.14079

By:

Jin, Kelly;
McCoy, Brianah M.;
Goldman, Elisabeth A.;
Usova, Viktoria;
Tkachev, Victor;
Chitsazan, Alex D.;
Kakebeen, Anneke;
Jeffery, Unity;
Creevy, Kate E.;
Wills, Andrea;
Snyder‐Mackler, Noah;
Promislow, Daniel E. L.

Publication type:

Article

Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64860

By:

Kaya, Alaattin;
Zi Jin Phua, Cheryl;
Lee, Mitchell;
Lu Wang;
Tyshkovskiy, Alexander;
Siming Ma;
Barre, Benjamin;
Weiqiang Liu;
Harrison, Benjamin R.;
Xiaqing Zhao;
Xuming Zhou;
Wasko, Brian M.;
Bammler, Theo K.;
EL Promislow, Daniel;
Kaeberlein, Matt;
Gladyshev, Vadim N.

Publication type:

Article

Drosophila serotonin 2A receptor signaling coordinates central metabolic processes to modulate aging in response to nutrient choice.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.59399

By:

Yang Lyu;
Weaver, Kristina J.;
Shaukat, Humza A.;
Plumoff, Marta L.;
Tjilos, Maria;
Promislow, Daniel E. L.;
Pletcher, Scott D.

Publication type:

Article

Reproductive Capability Is Associated with Lifespan and Cause of Death in Companion Dogs.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061082

By:

Hoffman, Jessica M.;
Creevy, Kate E.;
Promislow, Daniel E. L.

Publication type:

Article

The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster.

Published in:

BMC Genomics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12864-020-6739-1

By:

Harrison, Benjamin R.;
Wang, Lu;
Gajda, Erika;
Hoffman, Elise V.;
Chung, Brian Y.;
Pletcher, Scott D.;
Raftery, Daniel;
Promislow, Daniel E. L.

Publication type:

Article

Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila.

Published in:

PLoS Genetics, 2020, v. 16, n. 7, p. 1, doi. 10.1371/journal.pgen.1008835

By:

Jin, Kelly;
Wilson, Kenneth A.;
Beck, Jennifer N.;
Nelson, Christopher S.;
Brownridge III, George W.;
Harrison, Benjamin R.;
Djukovic, Danijel;
Raftery, Daniel;
Brem, Rachel B.;
Yu, Shiqing;
Drton, Mathias;
Shojaie, Ali;
Kapahi, Pankaj;
Promislow, Daniel

Publication type:

Article

Case report: Severe asymptomatic hypertriglyceridemia associated with long-term low-dose rapamycin administration in a healthy middle-aged Labrador retriever.

Published in:

Frontiers in Veterinary Science, 2023, p. 1, doi. 10.3389/fvets.2023.1285498

By:

Evans, Jeremy B.;
Chou, Lucy;
Kaeberlein, Matt;
Promislow, Daniel E. L.;
Creevy, Kate E.

Publication type:

Article

In Memory of George M. Martin.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 4, p. 619, doi. 10.1093/gerona/glac257

By:

Rabinovitch, Peter S;
Disteche, Christine;
Kaeberlein, Matt;
Martin, Kelsey C;
Monnat, Raymond J;
Oshima, Junko;
Promislow, Daniel

Publication type:

Article

Age and Physical Activity Levels in Companion Dogs: Results From the Dog Aging Project.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2022, v. 77, n. 10, p. 1986, doi. 10.1093/gerona/glac099

By:

Lee, Hannah;
Collins, Devin;
Creevy, Kate E;
Promislow, Daniel E L;
Consortium, Dog Aging Project;
Dog Aging Project Consortium

Publication type:

Article

A Metabolomic Aging Clock Using Human Cerebrospinal Fluid.

Published in:

2022

By:

Hwangbo, Nathan;
Zhang, Xinyu;
Raftery, Daniel;
Gu, Haiwei;
Hu, Shu-Ching;
Montine, Thomas J;
Quinn, Joseph F;
Chung, Kathryn A;
Hiller, Amie L;
Wang, Dongfang;
Fei, Qiang;
Bettcher, Lisa;
Zabetian, Cyrus P;
Peskind, Elaine;
Li, Gail;
Promislow, Daniel E L;
Franks, Alexander

Publication type:

journal article

The Effects of Graded Levels of Calorie Restriction: XVI. Metabolomic Changes in the Cerebellum Indicate Activation of Hypothalamocerebellar Connections Driven by Hunger Responses.

Published in:

2021

By:

Green, Cara L;
Mitchell, Sharon E;
Derous, Davina;
García-Flores, Libia A;
Wang, Yingchun;
Chen, Luonan;
Han, Jing-Dong J;
Promislow, Daniel E L;
Lusseau, David;
Douglas, Alex;
Speakman, John R

Publication type:

journal article

A New Concept in Diet Restriction Is Cleaning Up!

Published in:

2021

By:

Promislow, Daniel E L

Publication type:

journal article

Metabolic Signatures of Life Span Regulated by Mating, Sex Peptide, and Mifepristone/RU486 in Female Drosophila melanogaster.

Published in:

2021

By:

Landis, Gary N;
Doherty, Devon V;
Yen, Chia-An;
Wang, Lu;
Fan, Yang;
Wang, Ina;
Vroegop, Jonah;
Wang, Tianyi;
Wu, Jimmy;
Patel, Palak;
Lee, Shinwoo;
Abdelmesieh, Mina;
Shen, Jie;
Promislow, Daniel E L;
Curran, Sean P;
Tower, John

Publication type:

journal article

A Geroscience Perspective on COVID-19 Mortality.

Published in:

2020

By:

Promislow, Daniel E L

Publication type:

journal article

The Effects of Graded Levels of Calorie Restriction XV: Phase Space Attractors Reveal Distinct Behavioral Phenotypes.

Published in:

2020

By:

Sun, Deshun;
Liu, Fei;
Mitchell, Sharon E;
Ma, Huanfei;
Derous, Davina;
Wang, Yingchun;
Han, Jackie J D;
Promislow, Daniel E L;
Lusseau, David;
Douglas, Alex;
Speakman, John R;
Chen, Luonan

Publication type:

journal article

Biomarkers for Aging Identified in Cross-sectional Studies Tend to Be Non-causative.

Published in:

2020

By:

Nelson, Paul G;
Promislow, Daniel E L;
Masel, Joanna

Publication type:

journal article

The Effects of Graded Levels of Calorie Restriction: XIV. Global Metabolomics Screen Reveals Brown Adipose Tissue Changes in Amino Acids, Catecholamines, and Antioxidants After Short-Term Restriction in C57BL/6 Mice.

Published in:

2020

By:

Green, Cara L;
Mitchell, Sharon E;
Derous, Davina;
Wang, Yingchun;
Chen, Luonan;
Han, Jing-Dong J;
Promislow, Daniel E L;
Lusseau, David;
Douglas, Alex;
Speakman, John R

Publication type:

journal article

The Effects of Graded Levels of Calorie Restriction: XIII. Global Metabolomics Screen Reveals Graded Changes in Circulating Amino Acids, Vitamins, and Bile Acids in the Plasma of C57BL/6 Mice.

Published in:

2019

By:

Green, Cara L;
Soltow, Quinlyn A;
Mitchell, Sharon E;
Derous, Davina;
Wang, Yingchun;
Chen, Luonan;
Han, Jing-Dong J;
Promislow, Daniel E L;
Lusseau, David;
Douglas, Alex;
Jones, Dean P;
Speakman, John R

Publication type:

journal article

The Effects of Graded Levels of Calorie Restriction: X. Transcriptomic Responses of Epididymal Adipose Tissue.

Published in:

2018

By:

Derous, Davina;
Mitchell, Sharon E.;
Green, Cara L.;
Yingchun Wang;
Han, Jing Dong J.;
Luonan Chen;
Promislow, Daniel E. L.;
David Lusseau;
Alex Douglas;
Speakman, John R.;
Wang, Yingchun;
Chen, Luonan;
Lusseau, David;
Douglas, Alex

Publication type:

journal article

A Theory of Age-Dependent Mutation and Senescence.

Published in:

Genetics, 2008, v. 179, n. 4, p. 2061, doi. 10.1534/genetics.108.088526

By:

Moorad, Jacob A.;
Promislow, Daniel E. L.

Publication type:

Article

The effects of graded levels of calorie restriction: IV. Non-linear change in behavioural phenotype of mice in response to short-term calorie restriction.

Published in:

Scientific Reports, 2015, p. 13198, doi. 10.1038/srep13198

By:

Lusseau, David;
Mitchell, Sharon E.;
Barros, Ceres;
Derous, Davina;
Green, Cara;
Chen, Luonan;
Han, Jing-Dong Jackie;
Wang, Yingchun;
Promislow, Daniel E. L.;
Douglas, Alex;
Speakman, John R.

Publication type:

Article

Mate Choice, Sexual Conflict, and Evolution of Senescence.

Published in:

Behavior Genetics, 2003, v. 33, n. 2, p. 191, doi. 10.1023/A:1022562103669

By:

Promislow, Daniel

Publication type:

Article

Invariance and plasticity in the Drosophila melanogaster metabolomic network in response to temperature.

Published in:

BMC Systems Biology, 2014, v. 8, n. 1, p. 134, doi. 10.1186/s12918-014-0139-6

By:

Hariharan, Ramkumar;
Hoffman, Jessica M.;
Thomas, Ariel S.;
Soltow, Quinlyn A.;
Jones, Dean P.;
Promislow, Daniel E. L.

Publication type:

Article

Extending human healthspan and longevity: a symposium report.

Published in:

Annals of the New York Academy of Sciences, 2022, v. 1507, n. 1, p. 70, doi. 10.1111/nyas.14681

By:

DeVito, Loren M.;
Barzilai, Nir;
Cuervo, Ana Maria;
Niedernhofer, Laura J.;
Milman, Sofiya;
Levine, Morgan;
Promislow, Daniel;
Ferrucci, Luigi;
Kuchel, George A.;
Mannick, Joan;
Justice, Jamie;
Gonzales, Mitzi M.;
Kirkland, James L.;
Cohen, Pinchas;
Campisi, Judith

Publication type:

Article

Longevity and the barren aristocrat.

Published in:

Nature, 1998, v. 396, n. 6713, p. 719, doi. 10.1038/25440

By:

Promislow, Daniel E.L.

Publication type:

Article

Mifepristone Increases Life Span of Virgin Female Drosophila on Regular and High-fat Diet Without Reducing Food Intake.

Published in:

Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.751647

By:

Landis, Gary N.;
Hilsabeck, Tyler A. U.;
Bell, Hans S.;
Ronnen-Oron, Tal;
Wang, Lu;
Doherty, Devon V.;
Tejawinata, Felicia I.;
Erickson, Katherine;
Vu, William;
Promislow, Daniel E. L.;
Kapahi, Pankaj;
Tower, John

Publication type:

Article

Answering evolutionary questions: A guide for mechanistic biologists.

Published in:

BioEssays, 2016, v. 38, n. 7, p. 704, doi. 10.1002/bies.201600029

By:

Masel, Joanna;
Promislow, Daniel E. L.

Publication type:

Article

Correction: Genetic and metabolomic architecture of variation in diet restriction-mediated lifespan extension in Drosophila.

Published in:

2022

By:

Jin, Kelly;
Wilson, Kenneth A.;
Beck, Jennifer N.;
Nelson, Christopher S.;
Brownridge III, George W.;
Harrison, Benjamin R.;
Djukovic, Danijel;
Raftery, Daniel;
Brem, Rachel B.;
Yu, Shiqing;
Drton, Mathias;
Shojaie, Ali;
Kapahi, Pankaj;
Promislow, Daniel

Publication type:

Correction Notice

Age-Independent Cardiac Protection by Pharmacological Activation of Beclin-1 During Endotoxemia and Its Association With Energy Metabolic Reprograming in Myocardium-A Targeted Metabolomics Study.

Published in:

2022

By:

Kim, Matthew;
Nikouee, Azadeh;
Zou, Raymond;
Di Ren;
Zhibin He;
Ji Li;
Lu Wang;
Djukovic, Danijel;
Raftery, Daniel;
Purcell, Hayley;
Promislow, Daniel;
Yuxiao Sun;
Goodarzi, Mohammad;
Qing-Jun Zhang;
Zhi-Ping Liu;
Qun Sophia Zang;
Ren, Di;
He, Zhibin;
Li, Ji;
Wang, Lu

Publication type:

journal article

Systems biology approaches identify metabolic signatures of dietary lifespan and healthspan across species.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52909-y

By:

Hilsabeck, Tyler A. U.;
Narayan, Vikram P.;
Wilson, Kenneth A.;
Carrera, Enrique M.;
Raftery, Daniel;
Promislow, Daniel;
Brem, Rachel B.;
Campisi, Judith;
Kapahi, Pankaj

Publication type:

Article

THE ROLE OF AGE-STRUCTURE IN THE OPTIMAL GERMINATION FRACTION OF SEEDS.

Published in:

Mathematical & Computational Forestry & Natural Resource Sciences, 2014, v. 6, n. 1, p. 26

By:

Webster, Amy K.;
Cieszewski, Rene M.;
Promislow, Daniel E. L.

Publication type:

Article

Dog size and patterns of disease history across the canine age spectrum: Results from the Dog Aging Project.

Published in:

PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0295840

By:

Nam, Yunbi;
White, Michelle;
Karlsson, Elinor K.;
Creevy, Kate E.;
Promislow, Daniel E. L.;
McClelland, Robyn L.

Publication type:

Article

Immune parameter analysis of children with sickle cell disease on hydroxycarbamide or chronic transfusion therapy.

Published in:

British Journal of Haematology, 2015, v. 169, n. 4, p. 574, doi. 10.1111/bjh.13326

By:

Nickel, Robert S.;
Osunkwo, Ifeyinwa;
Garrett, Aneesah;
Robertson, Jennifer;
Archer, David R.;
Promislow, Daniel E.L.;
Horan, John T.;
Hendrickson, Jeanne E.;
Kean, Leslie S.

Publication type:

Article

Tissue-specific insulin signaling mediates female sexual attractiveness.

Published in:

PLoS Genetics, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pgen.1006935

By:

Fedina, Tatyana Y.;
Arbuthnott, Devin;
Rundle, Howard D.;
Promislow, Daniel E. L.;
Pletcher, Scott D.

Publication type:

Article

The dog aging project: translational geroscience in companion animals.

Published in:

Mammalian Genome, 2016, v. 27, n. 7/8, p. 279, doi. 10.1007/s00335-016-9638-7

By:

Kaeberlein, Matt;
Creevy, Kate;
Promislow, Daniel

Publication type:

Article