Works by Manes, Santos

Results: 39

Pathogens: raft hijackers.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 7, p. 557, doi. 10.1038/nri1129

By:

Manes, Santos;
del Real, Gustavo;
Martinez-A, Carlos

Publication type:

Article

Diacylglycerol kinase α inactivation is an integral component of the costimulatory pathway that amplifies TCR signals.

Published in:

Cancer Immunology, Immunotherapy, 2018, v. 67, n. 6, p. 965, doi. 10.1007/s00262-018-2154-8

By:

Arranz-Nicolás, Javier;
Ogando, Jesús;
Soutar, Denise;
Arcos-Pérez, Raquel;
Meraviglia-Crivelli, Daniel;
Mañes, Santos;
Mérida, Isabel;
Ávila-Flores, Antonia

Publication type:

Article

T cell costimulation by chemokine receptors.

Published in:

Nature Immunology, 2005, v. 6, n. 5, p. 465, doi. 10.1038/ni1191

By:

Molon, Barbara;
Gri, Giorgia;
Bettella, Monica;
Gómez-Moutón, Concepción;
Lanzavecchia, Antonio;
Martínez-A, Carlos;
Mañes, Santos;
Viola, Antonella

Publication type:

Article

Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement.

Published in:

Journal of Cell Biology, 2007, v. 179, n. 7, p. 1539, doi. 10.1083/jcb.200705044

By:

Lacalle, Rosa Ana;
Peregil, Rosa M.;
Albar, Juan Pablo;
Merino, Ernesto;
Martínez-A, Carlos;
Mérida, Isabel;
Mañes, Santos

Publication type:

Article

Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis.

Published in:

Journal of Cell Biology, 2004, v. 164, n. 5, p. 759, doi. 10.1083/jcb.200309101

By:

Gómez-Moutón, Concepci&oiacute;n;
Ana Lacalle, Rosa;
Mira, Emilia;
Jiménez-Baranda, Sonia;
Barber, Domingo F.;
Carrera, Ana C.;
Martínez-A, Carlos;
Mañes, Santos

Publication type:

Article

APRIL promotes breast tumor growth and metastasis and is associated with aggressive basal breast cancer.

Published in:

Carcinogenesis, 2015, v. 36, n. 5, p. 574, doi. 10.1093/carcin/bgv020

By:

García-Castro, Araceli;
Zonca, Manuela;
Florindo-Pinheiro, Douglas;
Carvalho-Pinto, Carla E.;
Cordero, Alex;
Fernando, Burgo Gutiérrez del;
García-Grande, Aránzazu;
Mañes, Santos;
Hahne, Michael;
González-Suárez, Eva;
Planelles, Lourdes

Publication type:

Article

Cells on the Move: A Dialogue Between Polarization and Motility.

Published in:

IUBMB Life, 2000, v. 49, n. 2, p. 89, doi. 10.1080/15216540050022386

By:

Manes, Santos;
Mira, Emilia;
Gomez-Mouton, Concepcion;
Lacalle, Rosa Ana;
Martinez-A, Carlos

Publication type:

Article

CCR5 deficiency impairs CD4<sup>+</sup> T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis.

Published in:

EMBO Journal, 2020, v. 39, n. 15, p. 1, doi. 10.15252/embj.2020104749

By:

Martín‐Leal, Ana;
Blanco, Raquel;
Casas, Josefina;
Sáez, María E;
Rodríguez‐Bovolenta, Elena;
Rojas, Itziar;
Drechsler, Carina;
Real, Luis Miguel;
Fabrias, Gemma;
Ruíz, Agustín;
Castro, Mario;
Schamel, Wolfgang WA;
Alarcón, Balbino;
Santen, Hisse M;
Mañes, Santos

Publication type:

Article

Type I phosphatidylinositol 4-phosphate 5-kinase homoand heterodimerization determines its membrane localization and activity.

Published in:

FASEB Journal, 2015, v. 29, n. 6, p. 2371, doi. 10.1096/fj.14-264606

By:

Lacalle, Rosa Ana;
de Karam, Juan C.;
Martínez-Muñoz, Laura;
Artetxe, Ibai;
Peregil, Rosa M.;
Sot, Jesús;
Rojas, Ana M.;
Goñi, Félix M.;
Mellado, Mario;
Mañes, Santos

Publication type:

Article

Identification of APOE phenotypes in microglia and neurons derived from isogenic hips cells: A study of the IMI ADAPTED consortium: Molecular and cell biology/stem cells, iPS cells.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042683

By:

Bahnassawy, Lamiaa;
Buchheit, Johanna;
Curado, Marco Rocha;
Ried, Janina S.;
Sáez, María Eugenia;
Nicolas, Armel;
Rao, Francesco;
Kaplan, Charlotte;
Mohler, Eric G.;
Lee, Heyne;
Untucht, Christopher;
Korffmann, Juergen;
Lakics, Viktor;
Cik, Miroslav;
Grezella, Clara;
Brustle, Oliver;
Peitz, Michael;
Mañes, Santos;
Ramaswamy, Gayathri;
Socorro, Alfredo Cabrera

Publication type:

Article

P3‐131: LOOKING FOR THERAPEUTIC ENTRY POINTS FOR ALZHEIMER'S DISEASE: LESSONS LEARNED FROM AGNOSTIC TRANS‐CO‐REGULATORY NETWORK ANALYSES OF APOE, TREM2, PLCG2 AND ABI3 LOCI.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1117, doi. 10.1016/j.jalz.2018.06.1488

By:

Ruiz, Agustín;
Madrid, Laura;
de Rojas, Itziar;
González-Pérez, Antonio;
Mañes, Santos;
Ramirez, Alfredo;
Hernández-Olasagarre, Begoña;
Sáez, María Eugenia

Publication type:

Article

Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients.

Published in:

Scientific Reports, 2016, p. 20223, doi. 10.1038/srep20223

By:

Ogando, Jesús;
Tardáguila, Manuel;
Díaz-Alderete, Andrea;
Usategui, Alicia;
Miranda-Ramos, Vanessa;
Martínez-Herrera, Dannys Jorge;
de la Fuente, Lorena;
García-León, María J.;
Moreno, María C.;
Escudero, Sara;
Cañete, Juan D.;
Toribio, María L.;
Cases, Ildefonso;
Pascual-Montano, Alberto;
Pablos, José Luis;
Mañes, Santos

Publication type:

Article

SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03079-1

By:

Mira, Emilia;
Carmona-Rodríguez, Lorena;
Pérez-Villamil, Beatriz;
Casas, Josefina;
Jesús Fernández-Aceñero, María;
Martínez-Rey, Diego;
Martín-González, Paula;
Heras-Murillo, Ignacio;
Paz-Cabezas, Mateo;
Tardáguila, Manuel;
Oury, Tim D.;
Martín-Puig, Silvia;
Ana Lacalle, Rosa;
Fabriás, Gemma;
Díaz-Rubio, Eduardo;
Mañes, Santos

Publication type:

Article

Immunometabolism Modulation in Therapy.

Published in:

Biomedicines, 2021, v. 9, n. 7, p. 798, doi. 10.3390/biomedicines9070798

By:

Monferrer, Ezequiel;
Sanegre, Sabina;
Vieco-Martí, Isaac;
López-Carrasco, Amparo;
Fariñas, Fernando;
Villatoro, Antonio;
Abanades, Sergio;
Mañes, Santos;
de la Cruz-Merino, Luis;
Noguera, Rosa;
Álvaro Naranjo, Tomás

Publication type:

Article

Molecular Classification of Colorectal Cancer by microRNA Profiling: Correlation with the Consensus Molecular Subtypes (CMS) and Validation of miR-30b Targets.

Published in:

Cancers, 2022, v. 14, n. 21, p. 5175, doi. 10.3390/cancers14215175

By:

Paz-Cabezas, Mateo;
Calvo-López, Tania;
Romera-Lopez, Alejandro;
Tabas-Madrid, Daniel;
Ogando, Jesus;
Fernández-Aceñero, María-Jesús;
Sastre, Javier;
Pascual-Montano, Alberto;
Mañes, Santos;
Díaz-Rubio, Eduardo;
Perez-Villamil, Beatriz

Publication type:

Article

Superoxide Dismutase-3 Downregulates Laminin α5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling.

Published in:

Cancers, 2022, v. 14, n. 5, p. 1226, doi. 10.3390/cancers14051226

By:

Carmona-Rodríguez, Lorena;
Martínez-Rey, Diego;
Martín-González, Paula;
Franch, Mónica;
Sorokin, Lydia;
Mira, Emilia;
Mañes, Santos

Publication type:

Article

The Tumour Vasculature as a Target to Modulate Leucocyte Trafficking.

Published in:

Cancers, 2021, v. 13, n. 7, p. 1724, doi. 10.3390/cancers13071724

By:

Zhao, Yang;
Ting, Ka Ka;
Coleman, Paul;
Qi, Yanfei;
Chen, Jinbiao;
Vadas, Mathew;
Gamble, Jennifer;
Manes, Santos

Publication type:

Article

The Importance of Mitochondrial Pyruvate Carrier in Cancer Cell Metabolism and Tumorigenesis.

Published in:

Cancers, 2021, v. 13, n. 7, p. 1488, doi. 10.3390/cancers13071488

By:

Ruiz-Iglesias, Ainhoa;
Mañes, Santos;
Bosca, Lisardo;
Castrillo, Antonio;
Lopez-Collazo, Eduardo

Publication type:

Article

Modulation of the Vascular-Immune Environment in Metastatic Cancer.

Published in:

Cancers, 2021, v. 13, n. 4, p. 810, doi. 10.3390/cancers13040810

By:

He, Bo;
Ganss, Ruth;
Mañes, Santos

Publication type:

Article

Variations in the Promoter Region of the Glutaminase Gene and the Development of Hepatic Encephalopathy in Patients With Cirrhosis.

Published in:

Annals of Internal Medicine, 2010, v. 153, n. 5, p. 281, doi. 10.7326/0003-4819-153-5-201009070-00002

By:

Romero-Gómez, Manuel;
Jover, María;
Del Campo, José A.;
Royo, José L.;
Hoyas, Elena;
Galán, José J.;
Montoliu, Carmina;
Baccaro, Eugenia;
Guevara, Mónica;
Córdoba, Juan;
Soriano, Germán;
Navarro, José M.;
Martínez-Sierra, Carmen;
Grande, Lourdes;
Galindo, Antonio;
Mira, Emilia;
Mañes, Santos;
Ruiz, Agustín

Publication type:

Article

Membrane raft microdomains mediate front-rear polarity in migrating cells.

Published in:

EMBO Journal, 1999, v. 18, n. 22, p. 6211, doi. 10.1093/emboj/18.22.6211

By:

Mañes, Santos;
Mira, Emilia;
Gomez-Mouton, Conception;
Lacalle, Rosa Ana;
Keller, Patrick;
Labrador, Juan Pablo;
Martinez-A, Carlos

Publication type:

Article

p21 mediates macrophage reprogramming through regulation of p50-p50 NF-κB and IFN-β.

Published in:

2016

By:

Rackov, Corjana;
Hernandez-Jimenez, Enrique;
Shokri, Rahman;
Carmona-Rodríguez, Lorena;
Mañes, Santos;
Álvarez-Mon, Melchor;
López-Collazo, Eduardo;
Martínez-A., Carlos;
Balomenos, Dimitrios;
Rackov, Gorjana;
Hernández-Jiménez, Enrique

Publication type:

journal article

Quantitative determination of tumor cell intravasation in a real-time polymerase chain reaction-based assay.

Published in:

Clinical & Experimental Metastasis, 2002, v. 19, n. 4, p. 313, doi. 10.1023/A:1015563031769

By:

Mira, Emilia;
Lacalle, Rosa;
Gómez-Moutón, Concepción;
Leonardo, Esther;
Mañes, Santos

Publication type:

Article

Differential regulation of components of the focal adhesion complex by heregulin: Role of phosphatase SHP-2.

Published in:

Journal of Cellular Physiology, 2002, v. 190, n. 2, p. 189, doi. 10.1002/jcp.10054

By:

Vadlamudi, Ratna K.;
Adam, Liana;
Nguyen, Diep;
Santos, Manes;
Kumar, Rakesh

Publication type:

Article

Novel interfering bifunctional molecules against the CCR5 coreceptor are efficient inhibitors of HIV-1 infection

Published in:

Molecular Therapy, 2003, v. 8, n. 3, p. 475, doi. 10.1016/S1525-0016(03)00202-8

By:

Luis Abad, José;
González, Manuel A.;
Real, Gustavo del;
Mira, Emilia;
Mañes, Santos;
Serrano, Fernando;
Bernad, Antonio

Publication type:

Article

Extracellular Superoxide Dismutase, the Endothelial Basement Membrane, and the WNT Pathway: New Players in Vascular Normalization and Tumor Infiltration by T-Cells.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.579552

By:

Martínez-Rey, Diego;
Carmona-Rodríguez, Lorena;
Fernández-Aceñero, María Jesús;
Mira, Emilia;
Mañes, Santos

Publication type:

Article

Role of T lymphocytes in tumor response to radiotherapy.

Published in:

Frontiers in Oncology, 2012, v. 2, p. 1, doi. 10.3389/fonc.2012.00095

By:

Demaria, Sandra;
Formenti, Silvia C.;
Mañes, Santos;
Repasky, Elizabeth Ann

Publication type:

Article

Notch activation stimulates migration of breast cancer cells and promotes tumor growth.

Published in:

Breast Cancer Research, 2013, v. 15, n. 4, p. 1, doi. 10.1186/bcr3447

By:

Bolós, Victoria;
Mira, Emilia;
Martínez-Poveda, Beatriz;
Luxán, Guillermo;
Cañamero, Marta;
Martínez-A, Carlos;
Mañes, Santos;
La Pompa, José Luis de

Publication type:

Article

Notch activation stimulates migration of breast cancer cells and promotes tumor growth.

Published in:

2013

By:

Bolós, Victoria;
Mira, Emilia;
Martínez-Poveda, Beatriz;
Luxán, Guillermo;
Cañamero, Marta;
Martínez-A, Carlos;
Mañes, Santos;
de la Pompa, José;
de la Pompa, José Luis

Publication type:

journal article

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.

Published in:

Molecular Cancer, 2010, v. 9, p. 196, doi. 10.1186/1476-4598-9-196

By:

Caffarel, María M.;
Andradas, Clara;
Mira, Emilia;
Pérez-Gómez, Eduardo;
Cerutti, Camilla;
Moreno-Bueno, Gema;
Flores, Juana M.;
García-Real, Isabel;
Palacios, José;
Mañes, Santos;
Guzmán, Manuel;
Sánchez, Cristina

Publication type:

Article

The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism.

Published in:

EMBO Reports, 2001, v. 2, n. 5, p. 446, doi. 10.1093/embo-reports/kve094

By:

Labrador, Juan Pablo;
Azcoitia, Valeria;
Tuckermann, Jan;
Lin, Calvin;
Olaso, Elvira;
Mañes, Santos;
Brückner, Katja;
Goergen, Jean-Louis;
Lemke, Greg;
Yancopoulos, George;
Angel, Peter;
Martínez-A, Carlos;
Klein, Rüdiger

Publication type:

Article

A role for chemokine receptor transactivation in growth factor signaling.

Published in:

2001

By:

Mira, Emilia;
Lacalle, Rosa Ana;
González, Manuel A.;
Gómez-Moutón, Concepción;
Abad, José Luis;
Bernad, Antonio;
Martínez-A., Carlos;
Mañes, Santos

Publication type:

Report

Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection.

Published in:

2000

By:

Mañes, Santos;
del Real, Gustavo;
Lacalle, Rosa Ana;
Lucas, Pilar;
Gómez-Moutón, Concepción;
Sánchez-Palomino, Sonsoles;
Delgado, Rafael;
Alcamí, José;
Mira, Emilia;
Martínez-A, Carlos

Publication type:

Report

Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation.

Published in:

Journal of Cell Biology, 2002, v. 157, n. 2, p. 277, doi. 10.1083/jcb.200109031

By:

Lacalle, Rosa Ana;
Mira, Emilia;
Gómez-Moutón, Concepción;
Jiménez-Baranda, Sonia;
Martínez-A., Carlos;
Mañes, Santos

Publication type:

Article

Establishment and Maintenance of Cell Polarity During Leukocyte Chemotaxis.

Published in:

Cell Adhesion & Migration, 2007, v. 1, n. 2, p. e1, doi. 10.4161/cam.1.2.4547

By:

Gómez-Moutón, Concepción;
Mañes, Santos

Publication type:

Article

Correlations between the NMR Lipoprotein Profile, APOE Genotype, and Cholesterol Efflux Capacity of Fasting Plasma from Cognitively Healthy Elderly Adults.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2186, doi. 10.3390/ijms24032186

By:

de Rojas, Itziar;
del Barrio, Laura;
Hernández, Isabel;
Montrreal, Laura;
García-González, Pablo;
Marquié, Marta;
Valero, Sergi;
Cano, Amanda;
Orellana, Adelina;
Boada, Mercè;
Mañes, Santos;
Ruiz, Agustín

Publication type:

Article

The Chemokine Receptor CCR5 Links Memory CD4<sup>+</sup> T Cell Metabolism to T Cell Antigen Receptor Nanoclustering.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.722320

By:

Blanco, Raquel;
Gómez de Cedrón, Marta;
Gámez-Reche, Laura;
Martín-Leal, Ana;
González-Martín, Alicia;
Lacalle, Rosa A.;
Ramírez de Molina, Ana;
Mañes, Santos

Publication type:

Article

Filamin-A regulates actin-dependent clustering of HIV receptors.

Published in:

Nature Cell Biology, 2007, v. 9, n. 7, p. 838, doi. 10.1038/ncb1610

By:

Jiménez-Baranda, Sonia;
Gómez-Moutón, Concepción;
Rojas, Ana;
Martínez-Prats, Lorena;
Mira, Emilia;
Ana Lacalle, Rosa;
Valencia, Alfonso;
Dimitrov, Dimiter S.;
Viola, Antonella;
Delgado, Rafael;
Martínez-A., Carlos;
Mañes, Santos

Publication type:

Article

CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse.

Published in:

Nature Cell Biology, 2006, v. 8, n. 11, p. 1270, doi. 10.1038/ncb1492

By:

Tavano, Regina;
Contento, Rita Lucia;
Baranda, Sonia Jimenez;
Soligo, Marzia;
Tuosto, Loretta;
Manes, Santos;
Viola, Antonella

Publication type:

Article