Works by Mak, Jeffrey Y. W.

Results: 32

Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.
Published in:
Angewandte Chemie, 2024, v. 136, n. 31, p. 1, doi. 10.1002/ange.202400632
By:
- Mak, Jeffrey Y. W.;
- Rivero, Ryan J. D.;
- Hoang, Huy N.;
- Lim, Xin Yi;
- Deng, Jieru;
- McWilliam, Hamish E. G.;
- Villadangos, Jose A.;
- McCluskey, James;
- Corbett, Alexandra J.;
- Fairlie, David P.
Publication type:
Article
Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides.
Published in:
Angewandte Chemie, 2022, v. 134, n. 29, p. 1, doi. 10.1002/ange.202203995
By:
- de Araujo, Aline D.;
- Hoang, Huy N.;
- Lim, Junxian;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.
Publication type:
Article
Varicella Zoster Virus disrupts MAIT cell polyfunctional effector responses.
Published in:
PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012372
By:
- Purohit, Shivam. K.;
- Stern, Lauren;
- Corbett, Alexandra J.;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Slobedman, Barry;
- Abendroth, Allison
Publication type:
Article
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.
Published in:
Journal of Cell Biology, 2022, v. 221, n. 12, p. 1, doi. 10.1083/jcb.202110125
By:
- Hui Jing Lim;
- Wubben, Jacinta M.;
- Garcia, Cristian Pinero;
- Cruz-Gomez, Sebastian;
- Deng, Jieru;
- Mak, Jeffrey Y. W.;
- Hachani, Abderrahman;
- Anderson, Regan J.;
- Painter, Gavin F.;
- Goyette, Jesse;
- Amarasinghe, Shanika L.;
- Ritchie, Matthew E.;
- Roquilly, Antoine;
- Fairlie, David P.;
- Gaus, Katharina;
- Rossjohn, Jamie;
- Villadangos, Jose A.;
- McWilliam, Hamish E. G.
Publication type:
Article
T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Published in:
Nature, 2014, v. 509, n. 7500, p. 361, doi. 10.1038/nature13160
By:
- Corbett, Alexandra J.;
- Eckle, Sidonia B. G.;
- Birkinshaw, Richard W.;
- Liu, Ligong;
- Patel, Onisha;
- Mahony, Jennifer;
- Chen, Zhenjun;
- Reantragoon, Rangsima;
- Meehan, Bronwyn;
- Cao, Hanwei;
- Williamson, Nicholas A.;
- Strugnell, Richard A.;
- Van Sinderen, Douwe;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Kjer-Nielsen, Lars;
- Rossjohn, Jamie;
- McCluskey, James
Publication type:
Article
Determination of Sample Concentrations by PULCON NMR Spectroscopy.
Published in:
Australian Journal of Chemistry, 2022, v. 75, n. 2, p. 160, doi. 10.1071/CH21149
By:
- Mak, Jeffrey Y. W.
Publication type:
Article
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.
Published in:
Angewandte Chemie International Edition, 2024, v. 63, n. 31, p. 1, doi. 10.1002/anie.202400632
By:
- Mak, Jeffrey Y. W.;
- Rivero, Ryan J. D.;
- Hoang, Huy N.;
- Lim, Xin Yi;
- Deng, Jieru;
- McWilliam, Hamish E. G.;
- Villadangos, Jose A.;
- McCluskey, James;
- Corbett, Alexandra J.;
- Fairlie, David P.
Publication type:
Article
MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection.
Published in:
Science Immunology, 2024, v. 9, n. 102, p. 1, doi. 10.1126/sciimmunol.adp9841
By:
- Wang, Huimeng;
- Souter, Michael N. T.;
- de Lima Moreira, Marcela;
- Li, Shihan;
- Zhou, Yuchen;
- Nelson, Adam G.;
- Yu, Jinhan;
- Meehan, Lucy J.;
- Meehan, Bronwyn S.;
- Eckle, Sidonia B. G.;
- Lee, Hyun Jae;
- Schröder, Jan;
- Haque, Ashraful;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- McCluskey, James;
- Wang, Zhongfang;
- Chen, Zhenjun;
- Corbett, Alexandra J.
Publication type:
Article
Sulfated bile acid is a host-derived ligand for MAIT cells.
Published in:
Science Immunology, 2024, v. 9, n. 91, p. 1, doi. 10.1126/sciimmunol.ade6924
By:
- Ito, Emi;
- Inuki, Shinsuke;
- Izumi, Yoshihiro;
- Takahashi, Masatomo;
- Dambayashi, Yuki;
- Ciacchi, Lisa;
- Awad, Wael;
- Takeyama, Ami;
- Shibata, Kensuke;
- Mori, Shotaro;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Bamba, Takeshi;
- Ishikawa, Eri;
- Nagae, Masamichi;
- Rossjohn, Jamie;
- Yamasaki, Sho
Publication type:
Article
An overview on the identification of MAIT cell antigens.
Published in:
Immunology & Cell Biology, 2018, v. 96, n. 6, p. 573, doi. 10.1111/imcb.12057
By:
- Kjer‐Nielsen, Lars;
- Corbett, Alexandra J.;
- Chen, Zhenjun;
- Liu, Ligong;
- Mak, Jeffrey Y. W.;
- Godfrey, Dale I.;
- Rossjohn, Jamie;
- Fairlie, David P.;
- McCluskey, James;
- Eckle, Sidonia B. G.
Publication type:
Article
Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14599, doi. 10.1038/ncomms14599
By:
- Mak, Jeffrey Y. W.;
- Xu, Weijun;
- Reid, Robert C.;
- Corbett, Alexandra J.;
- Meehan, Bronwyn S.;
- Wang, Huimeng;
- Chen, Zhenjun;
- Rossjohn, Jamie;
- McCluskey, James;
- Liu, Ligong;
- Fairlie, David P.
Publication type:
Article
Differential location of NKT and MAIT cells within lymphoid tissue.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07704-4
By:
- Johnson, Darryl N.;
- Ruan, Zheng;
- Petley, Emma V.;
- Devi, Sapna;
- Holz, Lauren E.;
- Uldrich, Adam P.;
- Mak, Jeffrey Y. W.;
- Hor, Jyh Liang;
- Mueller, Scott N.;
- McCluskey, James;
- Fairlie, David P.;
- Darcy, Phillip K.;
- Beavis, Paul A.;
- Heath, William R.;
- Godfrey, Dale I.
Publication type:
Article
MAIT cells protect against pulmonary Legionella longbeachae infection.
Published in:
Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05202-8
By:
- Huimeng Wang;
- D'Souza, Criselle;
- Xin Yi Lim;
- Kostenko, Lyudmila;
- Pediongco, Troi J.;
- Eckle, Sidonia B. G.;
- Meehan, Bronwyn S.;
- Mai Shi;
- Wang, Nancy;
- Shihan Li;
- Ligong Liu;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Yoichiro Iwakura;
- Gunnersen, Jennifer M.;
- Stent, Andrew W.;
- Godfrey, Dale I.;
- Rossjohn, Jamie;
- Westall, Glen P.;
- Kjer-Nielsen, Lars
Publication type:
Article
Stereoelectronic Effects on Dienophile Separation Influence the Diels-Alder Synthesis of Molecular Clefts.
Published in:
European Journal of Organic Chemistry, 2017, v. 2017, n. 45, p. 6793, doi. 10.1002/ejoc.201701319
By:
- Stoermer, Martin J.;
- Wickramasinghe, Wasantha A.;
- Byriel, Karl A.;
- Hockless, David C. R.;
- Skelton, Brian W.;
- Sobolev, Alexandre N.;
- White, Allan H.;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.
Publication type:
Article
Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides.
Published in:
Angewandte Chemie International Edition, 2022, v. 61, n. 29, p. 1, doi. 10.1002/anie.202203995
By:
- de Araujo, Aline D.;
- Hoang, Huy N.;
- Lim, Junxian;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.
Publication type:
Article
Recipient mucosal-associated invariant T cells control GVHD within the colon.
Published in:
2018
By:
- Varelias, Antiopi;
- Bunting, Mark D.;
- Ormerod, Kate L.;
- Koyama, Motoko;
- Olver, Stuart D.;
- Straube, Jasmin;
- Kuns, Rachel D.;
- Robb, Renee J.;
- Henden, Andrea S.;
- Cooper, Leanne;
- Lachner, Nancy;
- Gartlan, Kate H.;
- Lantz, Olivier;
- Kjer-Nielsen, Lars;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Clouston, Andrew D.;
- McCluskey, James;
- Rossjohn, Jamie;
- Lane, Steven W.
Publication type:
journal article
Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli.
Published in:
PLoS Biology, 2020, v. 18, n. 6, p. 1, doi. 10.1371/journal.pbio.3000644
By:
- Boulouis, Caroline;
- Sia, Wan Rong;
- Gulam, Muhammad Yaaseen;
- Teo, Jocelyn Qi Min;
- Png, Yi Tian;
- Phan, Thanh Kha;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Poon, Ivan K. H.;
- Koh, Tse Hsien;
- Bergman, Peter;
- Lim, Chwee Ming;
- Wang, Lin-Fa;
- Kwa, Andrea Lay Hoon;
- Sandberg, Johan K.;
- Leeansyah, Edwin
Publication type:
Article
Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.
Published in:
PLoS Pathogens, 2022, v. 18, n. 1, p. 1, doi. 10.1371/journal.ppat.1010166
By:
- Tran, Thao Thanh;
- Mathmann, Carmen D.;
- Gatica-Andrades, Marcela;
- Rollo, Rachel F.;
- Oelker, Melanie;
- Ljungberg, Johanna K.;
- Nguyen, Tam T. K.;
- Zamoshnikova, Alina;
- Kummari, Lalith K.;
- Wyer, Orry J. K.;
- Irvine, Katharine M.;
- Melo-Bolívar, Javier;
- Gross, Annette;
- Brown, Darren;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Hansford, Karl A.;
- Cooper, Matthew A.;
- Giri, Rabina;
- Schreiber, Veronika
Publication type:
Article
Computer Modelling and Synthesis of Deoxy and Monohydroxy Analogues of a Ribitylaminouracil Bacterial Metabolite that Potently Activates Human T Cells.
Published in:
Chemistry - A European Journal, 2019, v. 25, n. 68, p. 15594, doi. 10.1002/chem.201903732
By:
- Ler, Geraldine J. M.;
- Xu, Weijun;
- Mak, Jeffrey Y. W.;
- Liu, Ligong;
- Bernhardt, Paul V.;
- Fairlie, David P.
Publication type:
Article
Human MAIT cells respond to and suppress HIV-1.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.50324
By:
- Phetsouphanh, Chansavath;
- Phalora, Prabhjeet;
- Hackstein, Carl-Philipp;
- Thornhill, John;
- Munier, C. Mee Ling;
- Meyerowitz, Jodi;
- Murray, Lyle;
- VanVuuren, Cloete;
- Goedhals, Dominique;
- Drexhage, Linnea;
- Moore, Rebecca;
- Sattentau, Quentin J.;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Fidler, Sarah;
- Kelleher, Anthony D.;
- Frater, John;
- Klenerman, Paul
Publication type:
Article
Naturstoffe mit Anti-Bredt- und Brückenkopf-Doppelbindung.
Published in:
Angewandte Chemie, 2014, v. 126, n. 50, p. 13882, doi. 10.1002/ange.201400932
By:
- Mak, Jeffrey Y. W.;
- Pouwer, Rebecca H.;
- Williams, Craig M.
Publication type:
Article
Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1.
Published in:
Science Immunology, 2020, v. 5, n. 49, p. 1, doi. 10.1126/sciimmunol.abc9492
By:
- Howson, Lauren J.;
- Awad, Wael;
- von Borstel, Anouk;
- Lim, Hui Jing;
- McWilliam, Hamish E. G.;
- Sandoval-Romero, Maria L.;
- Majumdar, Shamik;
- Hamzeh, Abdul Rezzak;
- Andrews, Thomas D.;
- McDermott, David H.;
- Murphy, Philip M.;
- Le Nours, Jérôme;
- Mak, Jeffrey Y. W.;
- Liu, Ligong;
- Fairlie, David P.;
- McCluskey, James;
- Villadangos, Jose A.;
- Cook, Matthew C.;
- Turner, Stephen J.;
- Davey, Martin S.
Publication type:
Article
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection.
Published in:
Science Immunology, 2019, v. 4, n. 41, p. 1, doi. 10.1126/sciimmunol.aaw0402
By:
- Huimeng Wang;
- Kjer-Nielsen, Lars;
- Mai Shi;
- D’Souza, Criselle;
- Pediongco, Troi J.;
- Hanwei Cao;
- Kostenko, Lyudmila;
- Xin Yi Lim;
- Eckle, Sidonia B. G.;
- Meehan, Bronwyn S.;
- Tianyuan Zhu;
- Bingjie Wang;
- Zhe Zhao;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Teng, Michele W. L.;
- Rossjohn, Jamie;
- Di Yu;
- de St Groth, Barbara Fazekas;
- Lovrecz, George
Publication type:
Article
Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70615-9
By:
- Yu, Huifeng;
- Yang, Amy;
- Derrick, Steven;
- Mak, Jeffrey Y. W.;
- Liu, Ligong;
- Fairlie, David P.;
- Cowley, Siobhan
Publication type:
Article
Synthetic 5-amino-6-Dribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1109759
By:
- Nelson, Adam G.;
- Huimeng Wang;
- Dewar, Phoebe M.;
- Eddy, Eleanor M.;
- Songyi Li;
- Xin Yi Lim;
- Patton, Timothy;
- Yuchen Zhou;
- Pediongco, Troi J.;
- Meehan, Lucy J.;
- Meehan, Bronwyn S.;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Stent, Andrew W.;
- Kjer-Nielsen, Lars;
- McCluskey, James;
- Eckle, Sidonia B. G.;
- Corbett, Alexandra J.;
- Souter, Michael N. T.;
- Zhenjun Chen
Publication type:
Article
Identification and Phenotype of MAIT Cells in Cattle and Their Response to Bacterial Infections.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.627173
By:
- Edmans, Matthew D.;
- Connelley, Timothy K.;
- Jayaraman, Siddharth;
- Vrettou, Christina;
- Vordermeier, Martin;
- Mak, Jeffrey Y. W.;
- Liu, Ligong;
- Fairlie, David P.;
- Maze, Emmanuel Atangana;
- Chrun, Tiphany;
- Klenerman, Paul;
- Eckle, Sidonia B. G.;
- Tchilian, Elma;
- Benedictus, Lindert
Publication type:
Article
CXCL16 Stimulates Antigen-Induced MAIT Cell Accumulation but Trafficking During Lung Infection Is CXCR6-Independent.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.01773
By:
- Yu, Huifeng;
- Yang, Amy;
- Liu, Ligong;
- Mak, Jeffrey Y. W.;
- Fairlie, David P.;
- Cowley, Siobhan
Publication type:
Article
MAIT cells regulate NK cell-mediated tumor immunity.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25009-4
By:
- Petley, Emma V.;
- Koay, Hui-Fern;
- Henderson, Melissa A.;
- Sek, Kevin;
- Todd, Kirsten L.;
- Keam, Simon P.;
- Lai, Junyun;
- House, Imran G.;
- Li, Jasmine;
- Zethoven, Magnus;
- Chen, Amanda X. Y.;
- Oliver, Amanda J.;
- Michie, Jessica;
- Freeman, Andrew J.;
- Giuffrida, Lauren;
- Chan, Jack D.;
- Pizzolla, Angela;
- Mak, Jeffrey Y. W.;
- McCulloch, Timothy R.;
- Souza-Fonseca-Guimaraes, Fernando
Publication type:
Article
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24570-2
By:
- Zhao, Zhe;
- Wang, Huimeng;
- Shi, Mai;
- Zhu, Tianyuan;
- Pediongco, Troi;
- Lim, Xin Yi;
- Meehan, Bronwyn S.;
- Nelson, Adam G.;
- Fairlie, David P.;
- Mak, Jeffrey Y. W.;
- Eckle, Sidonia B. G.;
- de Lima Moreira, Marcela;
- Tumpach, Carolin;
- Bramhall, Michael;
- Williams, Cameron G.;
- Lee, Hyun Jae;
- Haque, Ashraful;
- Evrard, Maximilien;
- Rossjohn, Jamie;
- McCluskey, James
Publication type:
Article
Total Synthesis of (-)-Neovibsanin G and (-)-14- epi-Neovibsanin G: Towards the Synthesis of 15- O-Methylneovibsanin F and 14- epi-15- O-Methylneovibsanin F.
Published in:
European Journal of Organic Chemistry, 2012, v. 2012, n. 10, p. 2001, doi. 10.1002/ejoc.201101796
By:
- Mak, Jeffrey Y. W.;
- Williams, Craig M.
Publication type:
Article
Natural Products with Anti-Bredt and Bridgehead Double Bonds.
Published in:
Angewandte Chemie International Edition, 2014, v. 53, n. 50, p. 13664, doi. 10.1002/anie.201400932
By:
- Mak, Jeffrey Y. W.;
- Pouwer, Rebecca H.;
- Williams, Craig M.
Publication type:
Article
Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease.
Published in:
FEBS Journal, 2023, v. 290, n. 11, p. 2805, doi. 10.1111/febs.16437
By:
- Wang, Yizhuo;
- Abrol, Rishika;
- Mak, Jeffrey Y. W.;
- Das Gupta, Kaustav;
- Ramnath, Divya;
- Karunakaran, Denuja;
- Fairlie, David P.;
- Sweet, Matthew J.
Publication type:
Article