Works by Lengyel, Ernst

Results: 46

A cell atlas of the human fallopian tube throughout the menstrual cycle and menopause.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-55440-2

By:

Weigert, Melanie;
Li, Yan;
Zhu, Lisha;
Eckart, Heather;
Bajwa, Preety;
Krishnan, Rahul;
Ackroyd, Sarah;
Lastra, Ricardo;
Bilecz, Agnes;
Basu, Anindita;
Lengyel, Ernst;
Chen, Mengjie

Publication type:

Article

RADAR: differential analysis of MeRIP-seq data with a random effect model.

Published in:

Genome Biology, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s13059-019-1915-9

By:

Zhang, Zijie;
Zhan, Qi;
Eckert, Mark;
Zhu, Allen;
Chryplewicz, Agnieszka;
De Jesus, Dario F.;
Ren, Decheng;
Kulkarni, Rohit N.;
Lengyel, Ernst;
He, Chuan;
Chen, Mengjie

Publication type:

Article

FOXL2 and SOX9 Distinguish the Lineage of the Sex Cord-Stromal Cells in Gonadoblastomas.

Published in:

Pediatric & Developmental Pathology, 2011, v. 14, n. 5, p. 391, doi. 10.2350/10-12-0943-OA.1

By:

Buell-Gutbrod, Rebecca;
Ivanovic, Marina;
Montag, Anthony;
Lengyel, Ernst;
Fadare, Oluwole;
Gwin, Katja

Publication type:

Article

A Comparison of Obstetric Interventions and Outcomes Between Black and White Patients at an Urban Tertiary Medical Center.

Published in:

Reproductive Sciences, 2023, v. 30, n. 7, p. 2313, doi. 10.1007/s43032-023-01174-3

By:

Docheva, Nikolina;
Heimberger, Sarah;
Mueller, Ariel;
Bisson, Courtney;
Arenas, Gabriel;
Perdigao, Joana Lopes;
Kordik, Abbe;
Stewart, Karie;
Goodall, Perpetua;
Lengyel, Ernst;
Rana, Sarosh

Publication type:

Article

Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 10, p. 4614, doi. 10.1172/JCI74778

By:

Kenny, Hilary A.;
Chun-Yi Chiang;
White, Erin A.;
Schryver, Elizabeth M.;
Habis, Mohammed;
Romero, Iris L.;
Ladanyi, Andras;
Penicka, Carla V.;
George, Joshy;
Matlin, Karl;
Montag, Anthony;
Wroblewski, Kristen;
Yamada, S. Diane;
Mazar, Andrew P.;
Bowtell, David;
Lengyel, Ernst

Publication type:

Article

HOXA9 promotes ovarian cancer growth by stimulating cancer-associated fibroblasts.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 3603, doi. 10.1172/JCI62229

By:

Ko, Song Yi;
Barengo, Nicolas;
Ladanyi, Andras;
Ju-Seog Lee;
Marini, Frank;
Lengyel, Ernst;
Naora, Honami

Publication type:

Article

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

Published in:

2008

By:

Kenny, Hilary A.;
Kaur, Swayamjot;
Coussens, Lisa M.;
Lengyel, Ernst

Publication type:

journal article

Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0609-x

By:

Ko, Song Yi;
Lee, WonJae;
Kenny, Hilary A.;
Dang, Long H.;
Ellis, Lee M.;
Jonasch, Eric;
Lengyel, Ernst;
Naora, Honami

Publication type:

Article

Are We Ready for Hyperthermic Intraperitoneal Chemotherapy in the Upfront Treatment of Ovarian Cancer?

Published in:

2020

By:

Alter, Raanan;
Turaga, Kiran;
Lengyel, Ernst

Publication type:

Opinion

The glycoprotein CD147 defines miRNA‐enriched extracellular vesicles that derive from cancer cells.

Published in:

Journal of Extracellular Vesicles, 2023, v. 12, n. 4, p. 1, doi. 10.1002/jev2.12318

By:

Ko, Song Yi;
Lee, WonJae;
Weigert, Melanie;
Jonasch, Eric;
Lengyel, Ernst;
Naora, Honami

Publication type:

Article

Transient interaction of activated platelets with endothelial cells induces expression of monocyte-chemoattractant protein-1 via a p38 mitogen-activated protein kinase mediated pathway.

Published in:

Cardiovascular Research, 2001, v. 49, n. 1, p. 189, doi. 10.1016/S0008-6363(00)00220-0

By:

Dickfeld, Timm;
Lengyel, Ernst;
May, Andreas E;
Massberg, Steffen;
Brand, Korbinian;
Page, Sharon;
Thielen, Christiane;
Langenbrink, Kirsten;
Gawaz, Meinrad

Publication type:

Article

Regulation of urokinase-type plasminogen activator expression by an ERK1-dependent signaling pathway in a squamous cell carcinoma cell line.

Published in:

Journal of Cellular Biochemistry, 1996, v. 61, n. 3, p. 430, doi. 10.1002/(SICI)1097-4644(19960601)61:3<430::AID-JCB10>3.0.CO;2-N

By:

Lengyel, Ernst;
Gum, Rebecca;
Stepp, Evan;
Juarez, Jose;
Wang, Heng;
Boyd, Douglas

Publication type:

Article

Mutant p53 regulates LPA signaling through lysophosphatidic acid phosphatase type 6.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41352-5

By:

Chryplewicz, Agnieszka;
Tienda, Samantha M.;
Nahotko, Dominik A.;
Peters, Pamela N.;
Lengyel, Ernst;
Eckert, Mark A.

Publication type:

Article

Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum.

Published in:

International Journal of Cancer, 2007, v. 121, n. 7, p. 1463, doi. 10.1002/ijc.22874

By:

Kenny, Hilary A.;
Krausz, Thomas;
Yamada, Seiko D.;
Lengyel, Ernst

Publication type:

Article

C-Met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu.

Published in:

International Journal of Cancer, 2005, v. 113, n. 4, p. 678, doi. 10.1002/ijc.20598

By:

Lengyel, Ernst;
Prechtel, Dieter;
Resau, James H.;
Gauger, Katja;
Welk, Anita;
Lindemann, Kristina;
Salanti, Georgia;
Richter, Thomas;
Knudsen, Beatrice;
Vande Woude, George F.;
Harbeck, Nadia

Publication type:

Article

MMP-2 functions as an early response protein in ovarian cancer metastasis.

Published in:

Cell Cycle, 2009, v. 8, n. 5, p. 683, doi. 10.4161/cc.8.5.7703

By:

Kenny, Hilary A.;
Lengyel, Ernst

Publication type:

Article

Let-7 Prevents Early Cancer Progression by Suppressing Expression of the Embryonic Gene HMGA2.

Published in:

Cell Cycle, 2007, v. 6, n. 21, p. 2585, doi. 10.4161/cc.6.21.4845

By:

Park, Sun-Mi;
Shell, Scott;
Radjabi, Amir Reza;
Schickel, Robert;
Feig, Christine;
Boyerinas, Ben;
Dinulescu, Daniela M.;
Lengyel, Ernst;
Peter, Marcus E.

Publication type:

Article

UVB Increases Urokinase-Type Plasminogen Activator Receptor (uPAR) Expression.

Published in:

Journal of Investigative Dermatology, 1999, v. 113, n. 1, p. 69, doi. 10.1046/j.1523-1747.1999.00631.x

By:

Marschall, Christoph;
Lengyel, Ernst;
Nobutoh, Toshiko;
Braungart, Evelyn;
Douwes, Kathrin;
Simon, Aleksandra;
Magdolen, Viktor;
Reuning, Ute;
Degitz, Klaus

Publication type:

Article

Change in Health-Related Socioeconomic Risk Factors and Mental Health During the Early Phase of the COVID-19 Pandemic: A National Survey of U.S. Women.

Published in:

Journal of Women's Health (15409996), 2021, v. 30, n. 4, p. 502, doi. 10.1089/jwh.2020.8879

By:

Lindau, Stacy Tessler;
Makelarski, Jennifer A.;
Boyd, Kelly;
Doyle, Kate E.;
Haider, Sadia;
Kumar, Shivani;
Lee, Nita Karnik;
Pinkerton, El;
Tobin, Marie;
Vu, Milkie;
Wroblewski, Kristen E.;
Lengyel, Ernst

Publication type:

Article

Rethinking ovarian cancer: recommendations for improving outcomes.

Published in:

2011

By:

Vaughan, Sebastian;
Coward, Jermaine I.;
Bast, Robert C.;
Berchuck, Andy;
Berek, Jonathan S.;
Brenton, James D.;
Coukos, George;
Crum, Christopher C.;
Drapkin, Ronny;
Etemadmoghadam, Dariush;
Friedlander, Michael;
Gabra, Hani;
Kaye, Stan B.;
Lord, Chris J.;
Lengyel, Ernst;
Levine, Douglas A.;
McNeish, Iain A.;
Menon, Usha;
Mills, Gordon B.;
Nephew, Kenneth P.

Publication type:

journal article

Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1.

Published in:

International Journal of Cancer, 2012, v. 130, n. 8, p. 1787, doi. 10.1002/ijc.26190

By:

Boyerinas, Benjamin;
Park, Sun-Mi;
Murmann, Andrea E.;
Gwin, Katja;
Montag, Anton G.;
Zillhardt, Marion;
Hua, You-Jia;
Lengyel, Ernst;
Peter, Marcus E.

Publication type:

Article

Erratum: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Published in:

Nature Communications, 2016, v. 7, n. 2, p. 10649, doi. 10.1038/ncomms10649

By:

Kenny, Hilary A.;
Lal-Nag, Madhu;
White, Erin A.;
Shen, Min;
Chiang, Chun-Yi;
Mitra, Anirban K.;
Zhang, Yilin;
Curtis, Marion;
Schryver, Elizabeth M.;
Bettis, Sam;
Jadhav, Ajit;
Boxer, Matthew B.;
Li, Zhuyin;
Ferrer, Marc;
Lengyel, Ernst

Publication type:

Article

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Published in:

Nature Communications, 2015, v. 6, n. 2, p. 6220, doi. 10.1038/ncomms7220

By:

Kenny, Hilary A.;
Lal-Nag, Madhu;
White, Erin A.;
Shen, Min;
Chiang, Chun-Yi;
Mitra, Anirban K.;
Zhang, Yilin;
Curtis, Marion;
Schryver, Elizabeth M.;
Bettis, Sam;
Jadhav, Ajit;
Boxer, Matthew B.;
Li, Zhuyin;
Ferrer, Marc;
Lengyel, Ernst

Publication type:

Article

Resilience: a mediator of the negative effects of pandemic-related stress on women's mental health in the USA.

Published in:

Archives of Women's Mental Health, 2022, v. 25, n. 1, p. 137, doi. 10.1007/s00737-021-01184-7

By:

Kumar, Shivani;
Lee, Nita Karnik;
Pinkerton, Elizabeth;
Wroblewski, Kristen E.;
Lengyel, Ernst;
Tobin, Marie

Publication type:

Article

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference.

Published in:

2019

By:

Bast, Robert C.;
Sood, Anil K.;
Coleman, Robert L.;
Draetta, Giulio F.;
Futreal, Andrew;
Gershenson, David M.;
Lu, Zhen;
Mills, Gordon B.;
Doberstein, Kai;
Drapkin, Ronny I.;
Powell, Daniel J.;
Eckert, Mark A.;
Greenberg, Roger A.;
Lengyel, Ernst R.;
Edwards, Robert P.;
Modugno, Francesmary;
Elias, Kevin M.;
Ennis, Darren;
Walton, Josephine;
Huntsman, David G.

Publication type:

journal article

Comparative transcriptomic, epigenomic and immunological analyses identify drivers of disparity in high-grade serous ovarian cancer.

Published in:

NPJ Genomic Medicine, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41525-024-00448-2

By:

Huang, Hao;
Keathley, Russel;
Kim, Ujin;
Cardenas, Horacio;
Xie, Ping;
Wei, Jianjun;
Lengyel, Ernst;
Nephew, Kenneth P.;
Zhao, Guangyuan;
Fu, Zhen;
Barber, Emma L.;
Kocherginsky, Masha;
Bae-Jump, Victoria;
Zhang, Bin;
Matei, Daniela

Publication type:

Article

An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01854-0

By:

Gang Li;
Montgomery, Jeffrey E.;
Eckert, Mark A.;
Jae Won Chang;
Tienda, Samantha M.;
Lengyel, Ernst;
Moellering, Raymond E.

Publication type:

Article

Molecular Characterizations of Gynecologic Carcinosarcomas: A Focus on the Immune Microenvironment.

Published in:

Cancers, 2022, v. 14, n. 18, p. N.PAG, doi. 10.3390/cancers14184465

By:

Nakad Borrego, Sanaa;
Lengyel, Ernst;
Kurnit, Katherine C.

Publication type:

Article

The Natural Product β-Escin Targets Cancer and Stromal Cells of the Tumor Microenvironment to Inhibit Ovarian Cancer Metastasis.

Published in:

Cancers, 2021, v. 13, n. 16, p. 3931, doi. 10.3390/cancers13163931

By:

Kenny, Hilary A.;
Hart, Peter C.;
Kordylewicz, Kasjusz;
Lal, Madhu;
Shen, Min;
Kara, Betul;
Chen, Yen-Ju;
Grassl, Niklas;
Alharbi, Yousef;
Pattnaik, Bikash R.;
Watters, Karen M.;
Patankar, Manish S.;
Ferrer, Marc;
Lengyel, Ernst

Publication type:

Article

The Effects of Chemotherapeutics on the Ovarian Cancer Microenvironment.

Published in:

Cancers, 2021, v. 13, n. 13, p. 3136, doi. 10.3390/cancers13133136

By:

Eckert, Mark A.;
Orozco, Carlos;
Xiao, Jason;
Javellana, Melissa;
Lengyel, Ernst

Publication type:

Article

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.

Published in:

Nature Medicine, 2011, v. 17, n. 11, p. 1498, doi. 10.1038/nm.2492

By:

Nieman, Kristin M;
Kenny, Hilary A;
Penicka, Carla V;
Ladanyi, Andras;
Buell-Gutbrod, Rebecca;
Zillhardt, Marion R;
Romero, Iris L;
Carey, Mark S;
Mills, Gordon B;
Hotamisligil, Gökhan S;
Yamada, S Diane;
Peter, Marcus E;
Gwin, Katja;
Lengyel, Ernst

Publication type:

Article

AI-based automated segmentation for ovarian/adnexal masses and their internal components on ultrasound imaging.

Published in:

Journal of Medical Imaging, 2024, v. 11, n. 4, p. 44505, doi. 10.1117/1.JMI.11.4.044505

By:

Whitney, Heather M.;
Yoeli-Bik, Roni;
Abramowicz, Jacques S.;
Lan, Li;
Li, Hui;
Longman, Ryan E.;
Lengyel, Ernst;
Giger, Maryellen L.

Publication type:

Article

Statin Therapy Is Associated with Improved Survival in Patients with Non-Serous-Papillary Epithelial Ovarian Cancer: A Retrospective Cohort Analysis.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104521

By:

Habis, Mohammed;
Wroblewski, Kristen;
Bradaric, Michael;
Ismail, Nadia;
Yamada, S. Diane;
Litchfield, Lacey;
Lengyel, Ernst;
Romero, Iris L.

Publication type:

Article

Ovarian Masses: The Value of Acoustic Shadowing on Ultrasound Examination.

Published in:

Journal of Ultrasound in Medicine, 2023, v. 42, n. 4, p. 935, doi. 10.1002/jum.16100

By:

Yoeli‐Bik, Roni;
Lengyel, Ernst;
Mills, Kathryn A.;
Abramowicz, Jacques S.

Publication type:

Article

The adipocyte microenvironment and cancer.

Published in:

Cancer & Metastasis Reviews, 2022, v. 41, n. 3, p. 575, doi. 10.1007/s10555-022-10059-x

By:

Mukherjee, Abir;
Bilecz, Agnes J.;
Lengyel, Ernst

Publication type:

Article

Corrigendum: CD95 promotes tumour growth.

Published in:

2012

By:

Chen, Lina;
Park, Sun-Mi;
Tumanov, Alexei V.;
Hau, Annika;
Sawada, Kenjiro;
Feig, Christine;
Turner, Jerrold R.;
Fu, Yang-Xin;
Romero, Iris L.;
Lengyel, Ernst;
Peter, Marcus E.

Publication type:

Erratum

CD95 promotes tumour growth.

Published in:

2011

By:

Chen, Lina;
Park, Sun-Mi;
Tumanov, Alexei V.;
Hau, Annika;
Sawada, Kenjiro;
Feig, Christine;
Turner, Jerrold R.;
Fu, Yang-Xin;
Romero, Iris L.;
Lengyel, Ernst;
Peter, Marcus E.

Publication type:

Correction Notice

CD95 promotes tumour growth.

Published in:

2011

By:

Chen, Lina;
Park, Sun-Mi;
Tumanov, Alexei V.;
Hau, Annika;
Sawada, Kenjiro;
Feig, Christine;
Turner, Jerrold R.;
Fu, Yang-Xin;
Romero, Iris L.;
Lengyel, Ernst;
Peter, Marcus E.

Publication type:

Correction Notice

CD95 promotes tumour growth.

Published in:

Nature, 2010, v. 465, n. 7297, p. 492, doi. 10.1038/nature09075

By:

Chen, ,2Lina;
Park, Sun-Mi;
Tumanov, Alexei V.;
Hau, Annika;
Sawada, Kenjiro;
Feig, Christine;
Turner, Jerrold R.;
Fu, Yang-Xin;
Romero, Iris L.;
Lengyel, Ernst;
Peter, Marcus E.

Publication type:

Article

Healthy food for trainees: a call to action.

Published in:

2021

By:

Sackeim, Maryl G;
Lengyel, Ernst

Publication type:

Letter

Diagnostic Performance of Ultrasonography-Based Risk Models in Differentiating Between Benign and Malignant Ovarian Tumors in a US Cohort.

Published in:

JAMA Network Open, 2023, v. 6, n. 7, p. e2323289, doi. 10.1001/jamanetworkopen.2023.23289

By:

Yoeli-Bik, Roni;
Longman, Ryan E.;
Wroblewski, Kristen;
Weigert, Melanie;
Abramowicz, Jacques S.;
Lengyel, Ernst

Publication type:

Article

Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation.

Published in:

Oncogene, 2004, v. 23, n. 58, p. 9369, doi. 10.1038/sj.onc.1208182

By:

Singh, Anurag;
Karnoub, Antoine E.;
Palmby, Todd R.;
Lengyel, Ernst;
Sondek, John;
Der, Channing J.

Publication type:

Article

Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 19, p. 3632, doi. 10.1093/hmg/ddp312

By:

Deplazes, Joëlle;
Fuchs, Margit;
Rauser, Sandra;
Genth, Harald;
Lengyel, Ernst;
Busch, Raymonde;
Luber, Birgit

Publication type:

Article

Tumor microenvironment-induced FOXM1 regulates ovarian cancer stemness.

Published in:

Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06767-7

By:

Battistini, Chiara;
Kenny, Hilary A.;
Zambuto, Melissa;
Nieddu, Valentina;
Melocchi, Valentina;
Decio, Alessandra;
Lo Riso, Pietro;
Villa, Carlo Emanuele;
Gatto, Alessia;
Ghioni, Mariacristina;
Porta, Francesca M.;
Testa, Giuseppe;
Giavazzi, Raffaella;
Colombo, Nicoletta;
Bianchi, Fabrizio;
Lengyel, Ernst;
Cavallaro, Ugo

Publication type:

Article

Deep Visual Proteomics defines single-cell identity and heterogeneity.

Published in:

Nature Biotechnology, 2022, v. 40, n. 8, p. 1231, doi. 10.1038/s41587-022-01302-5

By:

Mund, Andreas;
Coscia, Fabian;
Kriston, András;
Hollandi, Réka;
Kovács, Ferenc;
Brunner, Andreas-David;
Migh, Ede;
Schweizer, Lisa;
Santos, Alberto;
Bzorek, Michael;
Naimy, Soraya;
Rahbek-Gjerdrum, Lise Mette;
Dyring-Andersen, Beatrice;
Bulkescher, Jutta;
Lukas, Claudia;
Eckert, Mark Adam;
Lengyel, Ernst;
Gnann, Christian;
Lundberg, Emma;
Horvath, Peter

Publication type:

Article

A streamlined mass spectrometry–based proteomics workflow for large‐scale FFPE tissue analysis.

Published in:

Journal of Pathology, 2020, v. 251, n. 1, p. 100, doi. 10.1002/path.5420

By:

Coscia, Fabian;
Doll, Sophia;
Bech, Jacob Mathias;
Schweizer, Lisa;
Mund, Andreas;
Lengyel, Ernst;
Lindebjerg, Jan;
Madsen, Gunvor Iben;
Moreira, José MA;
Mann, Matthias

Publication type:

Article