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SGLT2 Inhibitor Dapagliflozin Increases Skeletal Muscle and Brain Fatty Acid Uptake in Individuals With Type 2 Diabetes: A Randomized Double-Blind Placebo-Controlled Positron Emission Tomography Study.
Published in:
Diabetes Care, 2024, v. 47, n. 9, p. 1630, doi. 10.2337/dc24-0470
By:
- Latva-Rasku, Aino;
- Rebelos, Eleni;
- Tuisku, Jouni;
- Aarnio, Richard;
- Bhowmik, Achol;
- Keskinen, Helmi;
- Laurila, Sanna;
- Lahesmaa-Hatting, Minna;
- Pekkarinen, Laura;
- Isackson, Henrik;
- Kirjavainen, Anna K.;
- Koffert, Jukka;
- Heurling, Kerstin;
- Nummenmaa, Lauri;
- Ferrannini, Ele;
- Oldgren, Jonas;
- Oscarsson, Jan;
- Nuutila, Pirjo
Publication type:
Article
Effects of 6 weeks of treatment with dapagliflozin, a sodium‐glucose co‐transporter‐2 inhibitor, on myocardial function and metabolism in patients with type 2 diabetes: A randomized, placebo‐controlled, exploratory study.
Published in:
Diabetes, Obesity & Metabolism, 2021, v. 23, n. 7, p. 1505, doi. 10.1111/dom.14363
By:
- Oldgren, Jonas;
- Laurila, Sanna;
- Åkerblom, Axel;
- Latva‐Rasku, Aino;
- Rebelos, Eleni;
- Isackson, Henrik;
- Saarenhovi, Maria;
- Eriksson, Olof;
- Heurling, Kerstin;
- Johansson, Edvin;
- Wilderäng, Ulrica;
- Karlsson, Cecilia;
- Esterline, Russell;
- Ferrannini, Ele;
- Oscarsson, Jan;
- Nuutila, Pirjo
Publication type:
Article
A Partial Loss-of-Function Variant in Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study.
Published in:
2018
By:
- Latva-Rasku, Aino;
- Honka, Miikka-Juhani;
- Stancáková, Alena;
- Koistinen, Heikki A.;
- Kuusisto, Johanna;
- Li Guan;
- Manning, Alisa K.;
- Stringham, Heather;
- Gloyn, Anna L.;
- Lindgren, Cecilia M.;
- Collins, Francis S.;
- Mohlke, Karen L.;
- Scott, Laura J.;
- Karjalainen, Tomi;
- Nummenmaa, Lauri;
- Boehnke, Michael;
- Nuutila, Pirjo;
- Laakso, Markku;
- Stančáková, Alena;
- Guan, Li
Publication type:
journal article
Obesity risk is associated with brain glucose uptake and insulin resistance.
Published in:
European Journal of Endocrinology, 2022, v. 187, n. 6, p. 917, doi. 10.1530/EJE-22-0509
By:
- Pekkarinen, Laura;
- Kantonen, Tatu;
- Rebelos, Eleni;
- Latva-Rasku, Aino;
- Dadson, Prince;
- Karjalainen, Tomi;
- Bucci, Marco;
- Kalliokoski, Kari;
- Laitinen, Kirsi;
- Houttu, Noora;
- Kirjavainen, Anna K.;
- Rajander, Johan;
- Rönnemaa, Tapani;
- Nummenmaa, Lauri;
- Nuutila, Pirjo
Publication type:
Article
Insulin-stimulated glucose uptake in skeletal muscle, adipose tissue and liver: a positron emission tomography study.
Published in:
European Journal of Endocrinology, 2018, v. 178, n. 5, p. 523, doi. 10.1530/EJE-17-0882
By:
- Honka, Miikka-Juhani;
- Latva-Rasku, Aino;
- Bucci, Marco;
- Virtanen, Kirsi A.;
- Hannukainen, Jarna C.;
- Kalliokoski, Kari K.;
- Nuutila, Pirjo
Publication type:
Article
Quantitative Perfusion Imaging with Total-Body PET.
Published in:
Journal of Nuclear Medicine, 2023, v. 64, p. 11S, doi. 10.2967/jnumed.122.264870
By:
- Knuuti, Juhani;
- Tuisku, Jouni;
- Kärpijoki, Henri;
- Iida, Hidehiro;
- Maaniitty, Teemu;
- Latva-Rasku, Aino;
- Oikonen, Vesa;
- Nesterov, Sergey V.;
- Teuho, Jarmo;
- Jaakkola, Maria K.;
- Klén, Riku;
- Louhi, Heli;
- Saunavaara, Virva;
- Nuutila, Pirjo;
- Saraste, Antti;
- Rinne, Juha;
- Nummenmaa, Lauri
Publication type:
Article
Renal Cortical Glucose Uptake Is Decreased in Insulin Resistance and Correlates Inversely With Serum Free-fatty Acids.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 4, p. 1033, doi. 10.1210/clinem/dgad663
By:
- Rebelos, Eleni;
- Mari, Andrea;
- Honka, Miikka-Juhani;
- Pekkarinen, Laura;
- Latva-Rasku, Aino;
- Laurila, Sanna;
- Rajander, Johan;
- Salminen, Paulina;
- Iida, Hidehiro;
- Ferrannini, Ele;
- Nuutila, Pirjo
Publication type:
Article
Insulin-stimulated brain glucose uptake correlates with brain metabolites in severe obesity: A combined neuroimaging study.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2024, v. 44, n. 3, p. 407, doi. 10.1177/0271678X231207114
By:
- Rebelos, Eleni;
- Latva-Rasku, Aino;
- Koskensalo, Kalle;
- Pekkarinen, Laura;
- Saukko, Ekaterina;
- Ihalainen, Jukka;
- Honka, Miikka-Juhani;
- Tuisku, Jouni;
- Bucci, Marco;
- Laurila, Sanna;
- Rajander, Johan;
- Salminen, Paulina;
- Nummenmaa, Lauri;
- Jansen, Jacobus FA;
- Ferrannini, Ele;
- Nuutila, Pirjo
Publication type:
Article
Lower abdominal adipose tissue cannabinoid type 1 receptor availability in young men with overweight.
Published in:
Obesity (19307381), 2023, v. 31, n. 7, p. 1844, doi. 10.1002/oby.23770
By:
- Pekkarinen, Laura;
- Kantonen, Tatu;
- Oikonen, Vesa;
- Haaparanta‐Solin, Merja;
- Aarnio, Richard;
- Dickens, Alex M.;
- von Eyken, Annie;
- Latva‐Rasku, Aino;
- Dadson, Prince;
- Kirjavainen, Anna K.;
- Rajander, Johan;
- Kalliokoski, Kari;
- Rönnemaa, Tapani;
- Nummenmaa, Lauri;
- Nuutila, Pirjo
Publication type:
Article
Both sedentary time and physical activity are associated with cardiometabolic health in overweight adults in a 1 month accelerometer measurement.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77637-3
By:
- Sjöros, Tanja;
- Vähä-Ypyä, Henri;
- Laine, Saara;
- Garthwaite, Taru;
- Lahesmaa, Minna;
- Laurila, Sanna M.;
- Latva-Rasku, Aino;
- Savolainen, Anna;
- Miikkulainen, Annika;
- Löyttyniemi, Eliisa;
- Sievänen, Harri;
- Kalliokoski, Kari K.;
- Knuuti, Juhani;
- Vasankari, Tommi;
- Heinonen, Ilkka H. A.
Publication type:
Article
Brain insulin sensitivity is linked to body fat distribution—the positron emission tomography perspective.
Published in:
2021
By:
- Rebelos, Eleni;
- Nummenmaa, Lauri;
- Dadson, Prince;
- Latva-Rasku, Aino;
- Nuutila, Pirjo
Publication type:
Letter
Predicting Skeletal Muscle and Whole-Body Insulin Sensitivity Using NMR-Metabolomic Profiling.
Published in:
Journal of the Endocrine Society, 2020, v. 4, n. 4, p. N.PAG, doi. 10.1210/jendso/bvaa026
By:
- Klén, Riku;
- Honka, Miikka-Juhani;
- Hannukainen, Jarna C;
- Huovinen, Ville;
- Bucci, Marco;
- Latva-Rasku, Aino;
- Venäläinen, Mikko S;
- Kalliokoski, Kari K;
- Virtanen, Kirsi A;
- Lautamäki, Riikka;
- Iozzo, Patricia;
- Elo, Laura L;
- Nuutila, Pirjo
Publication type:
Article
Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort.
Published in:
2021
By:
- Rebelos, Eleni;
- Bucci, Marco;
- Karjalainen, Tomi;
- Oikonen, Vesa;
- Bertoldo, Alessandra;
- Hannukainen, Jarna C.;
- Virtanen, Kirsi A.;
- Latva-Rasku, Aino;
- Hirvonen, Jussi;
- Heinonen, Ilkka;
- Parkkola, Riitta;
- Laakso, Markku;
- Ferrannini, Ele;
- Iozzo, Patricia;
- Nummenmaa, Lauri;
- Nuutila, Pirjo
Publication type:
journal article
The SGLT2 Inhibitor Dapagliflozin Reduces Liver Fat but Does Not Affect Tissue Insulin Sensitivity: A Randomized, Double-Blind, Placebo-Controlled Study With 8-Week Treatment in Type 2 Diabetes Patients.
Published in:
2019
By:
- Latva-Rasku, Aino;
- Honka, Miikka-Juhani;
- Kullberg, Joel;
- Mononen, Nina;
- Lehtimäki, Terho;
- Saltevo, Juha;
- Kirjavainen, Anna K.;
- Saunavaara, Virva;
- Iozzo, Patricia;
- Johansson, Lars;
- Oscarsson, Jan;
- Hannukainen, Jarna C.;
- Nuutila, Pirjo
Publication type:
journal article

Found: 14