Works by Krammer, Peter H.

Results: 124

Life and death in peripheral T cells.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 7, p. 532, doi. 10.1038/nri2115

By:

Krammer, Peter H.;
Arnold, Rüdiger;
Lavrik, Inna N.

Publication type:

Article

Regulation of IL4 gene expression by T cells and therapeutic perspectives.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 7, p. 534, doi. 10.1038/nri1128

By:

Li-Weber, Min;
Krammer, Peter H.

Publication type:

Article

Apoptotic cell death induced by a mouse-human anti-APO-1 chimeric antibody leads to tumor regression.

Published in:

International Journal of Cancer, 1994, v. 58, n. 4, p. 562, doi. 10.1002/ijc.2910580419

By:

Coney, Leslie R.;
Daniel, Peter T.;
Sanborn, David;
Dhein, Jens;
Debatin, Klaus-Michael;
Krammer, Peter H.;
Zurawski, V. R.

Publication type:

Article

Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium.

Published in:

International Journal of Cancer, 1994, v. 57, n. 3, p. 371, doi. 10.1002/ijc.2910570314

By:

Möller, Peter;
Koretz, Karin;
Leithäuser, Frank;
Brüderlein, Silke;
Henne, Christof;
Quentmeier, Armin;
Krammer, Peter H.

Publication type:

Article

Neutralization of CD95 ligand protects the liver against ischemia-reperfusion injury and prevents acute liver failure.

Published in:

Cell Death & Disease, 2018, v. 9, n. 2, p. 1, doi. 10.1038/s41419-017-0150-0

By:

Al-Saeedi, Mohammed;
Steinebrunner, Niels;
Kudsi, Hassan;
Halama, Niels;
Mogler, Carolin;
Büchler, Markus W.;
Krammer, Peter H.;
Schemmer, Peter;
Müller, Martina

Publication type:

Article

Suramin inhibits death receptor-induced apoptosis in vitro and fulminant apoptotic liver damage in mice.

Published in:

Nature Medicine, 2004, v. 10, n. 6, p. 602, doi. 10.1038/nm1049

By:

Eichhorst, Sörem T.;
Krueger, Andreas;
Müerköster, Susanne;
Fas, Stefanie C.;
Golks, Alexander;
Gruetzner, Uwe;
Shubert, Louise;
Opelz, Christine;
Bilzer, Manfred;
Gerbes, Alexander L.;
Krammer, Peter H.

Publication type:

Article

Neutralization of CD95 ligand promotes regeneration and functional recovery after spinal cord injury.

Published in:

Nature Medicine, 2004, v. 10, n. 4, p. 389, doi. 10.1038/nm1007

By:

Demjen, Deana;
Klussmann, Stefan;
Kleber, Susanne;
Zuliani, Cecilia;
Stieltjes, Bram;
Metzger, Corinna;
Hirt, Ulrich A.;
Walczak, Henning;
Falk, Werner;
Essig, Marco;
Edler, Lutz;
Krammer, Peter H.;
Martin-Villalba, Ana

Publication type:

Article

A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 2, p. 787, doi. 10.3390/ijms26020787

By:

Poisa-Beiro, Laura;
Landry, Jonathan J. M.;
Yan, Bowen;
Kardorff, Michael;
Eckstein, Volker;
Villacorta, Laura;
Krammer, Peter H.;
Zaugg, Judith;
Gavin, Anne-Claude;
Benes, Vladimir;
Zhou, Daohong;
Raffel, Simon;
Ho, Anthony D.

Publication type:

Article

Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction.

Published in:

BMC Cancer, 2006, v. 6, p. 232, doi. 10.1186/1471-2407-6-232

By:

Henning Schulze-Bergkamen;
Binje Fleischer;
Marcus Schuchmann;
Achim Weber;
Arndt Weinmann;
Peter H Krammer;
Peter R Galle

Publication type:

Article

Tumor counterattack: fact or fiction?

Published in:

Cancer Immunology, Immunotherapy, 2005, v. 54, n. 11, p. 1127, doi. 10.1007/s00262-005-0680-7

By:

Igney, Frederik H.;
Krammer, Peter H.

Publication type:

Article

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.

Published in:

Journal of Cell Biology, 2010, v. 190, n. 3, p. 377, doi. 10.1083/jcb.201002060

By:

Fricker, Nicolai;
Beaudouin, Joel;
Richter, Petra;
Eils, Roland;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

Annexin A1 on the Surface of Early Apoptotic Cells Suppresses CD8+ T Cell Immunity.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062449

By:

Weyd, Heiko;
Abeler-Dörner, Lucie;
Linke, Björn;
Mahr, Andrea;
Jahndel, Veronika;
Pfrang, Sandra;
Schnölzer, Martina;
Falk, Christine S.;
Krammer, Peter H.

Publication type:

Article

Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019927

By:

Shatnyeva, Olga M.;
Kubarenko, Andriy V.;
Weber, Claudia E. M.;
Pappa, Alexander;
Schwartz-Albiez, Reinhard;
Weber, Alexander N. R.;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

Intracerebral Human Regulatory T Cells: Analysis of CD4+CD25+FOXP3+ T Cells in Brain Lesions and Cerebrospinal Fluid of Multiple Sclerosis Patients.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017988

By:

Fritzsching, Benedikt;
Haas, Jürgen;
König, Fatima;
Kunz, Pierre;
Fritzsching, Eva;
Pöschl, Johannes;
Krammer, Peter H.;
Brück, Wolfgang;
Suri-Payer, Elisabeth;
Wildemann, Brigitte

Publication type:

Article

Up-regulation of Fas (CD95) expression in tumour cells in vivo.

Published in:

Immunology, 2007, v. 120, n. 4, p. 502, doi. 10.1111/j.1365-2567.2006.02521.x

By:

Peshes-Yaloz, Naama;
Rosen, Dalia;
Sondel, Paul M.;
Krammer, Peter H.;
Berke, Gideon

Publication type:

Article

FasL (CD95L/APO-1L) Resistance of Neurons Mediated by Phosphatidylinositol 3-Kinase-Akt/Protein Kinase B-Dependent Expression of Lifeguard/Neuronal Membrane Protein 35.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 29, p. 6765, doi. 10.1523/JNEUROSCI.1700-05.2005

By:

Beier, Christoph P.;
Wischhusen, Jörg;
Gleichmann, Marc;
Gerhardt, Ellen;
Pekanovic, Ana;
Krueger, Andreas;
Taylor, Verdon;
Suter, Ueli;
Krammer, Peter H.;
Endres, Matthias;
Weller, Michael;
Schulz, Jörg B.

Publication type:

Article

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.6

By:

Neumann, Leo;
Pforr, Carina;
Beaudouin, Joel;
Pappa, Alexander;
Fricker, Nicolai;
Krammer, Peter H;
Lavrik, Inna N;
Eils, Roland

Publication type:

Article

Ultrastructural Analysis of Apoptosis Induced by the Monoclonal Antibody Anti-APO-1 on a Lymphoblastoid B Cell Line.

Published in:

Ultrastructural Pathology, 1990, v. 14, n. 6, p. 513, doi. 10.3109/01913129009076138

By:

Köhler, Heinz-RÜdiger;
Dhein, Jens;
Alberti, Gerd;
Krammer, Peter H.

Publication type:

Article

Human Regulatory T Cells Rapidly Suppress T Cell Receptor-Induced Ca2+, NF-κB, and NFAT Signaling in Conventional T Cells.

Published in:

Science Signaling, 2011, v. 4, n. 204, p. 1, doi. 10.1126/scisignal.2002179

By:

Schmidt, Angelika;
Oberle, Nina;
Weiß, Eva-Maria;
Vobis, Diana;
Frischbutter, Stefan;
Baumgrass, Ria;
Falk, Christine S.;
Haag, Mathias;
Brügger, Britta;
Lin, Hongying;
Mayr, Georg W.;
Reichardt, Peter;
Gunzer, Matthias;
Suri-Payer, Elisabeth;
Krammer, Peter H.

Publication type:

Article

Caspases: pharmacological manipulation of cell death.

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 10, p. 2665, doi. 10.1172/JCI26252

By:

Lavrik, Inna N.;
Golks, Alexander;
Krammer, Peter H.

Publication type:

Article

Annexin-coated particles induce antigen-specific immunosuppression.

Published in:

Autoimmunity, 2020, v. 53, n. 2, p. 86, doi. 10.1080/08916934.2019.1710134

By:

Link, Corinna;
Bujupi, Fatmire;
Krammer, Peter H.;
Weyd, Heiko

Publication type:

Article

Targeting Thioredoxin-1 by dimethyl fumarate induces ripoptosome-mediated cell death.

Published in:

Scientific Reports, 2017, p. 43168, doi. 10.1038/srep43168

By:

Schroeder, Anne;
Warnken, Uwe;
Röth, Daniel;
Klika, Karel D.;
Vobis, Diana;
Barnert, Andrea;
Bujupi, Fatmire;
Oberacker, Tina;
Schnölzer, Martina;
Nicolay, Jan P.;
Krammer, Peter H.;
Gülow, Karsten

Publication type:

Article

HTLV-1-associated adult T cell leukemia is highly susceptible to Navitoclax due to enhanced Bax expression.

Published in:

International Journal of Cancer, 2016, v. 138, n. 2, p. 507, doi. 10.1002/ijc.29726

By:

Witzens‐Harig, Mathias;
Giaisi, Marco;
Köhler, Rebecca;
Krammer, Peter H.;
Li‐Weber, Min

Publication type:

Article

Mangrove dolabrane-type of diterpenes tagalsins suppresses tumor growth via ROS-mediated apoptosis and ATM/ATR-Chk1/Chk2-regulated cell cycle arrest.

Published in:

International Journal of Cancer, 2015, v. 137, n. 11, p. 2739, doi. 10.1002/ijc.29629

By:

Neumann, Jennifer;
Yang, Yi;
Köhler, Rebecca;
Giaisi, Marco;
Witzens‐Harig, Mathias;
Liu, Dong;
Krammer, Peter H.;
Lin, Wenhan;
Li‐Weber, Min

Publication type:

Article

Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263.

Published in:

International Journal of Cancer, 2015, v. 136, n. 3, p. 688, doi. 10.1002/ijc.29009

By:

Polier, Gernot;
Giaisi, Marco;
Köhler, Rebecca;
Müller, Wolfgang W.;
Lutz, Christoph;
Buss, Eike C.;
Krammer, Peter H.;
Li‐Weber, Min

Publication type:

Article

The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.

Published in:

International Journal of Cancer, 2014, v. 134, n. 8, p. 1991, doi. 10.1002/ijc.28521

By:

Neumann, Jennifer;
Boerries, Melanie;
Köhler, Rebecca;
Giaisi, Marco;
Krammer, Peter H.;
Busch, Hauke;
Li‐Weber, Min

Publication type:

Article

The Wilms' tumor suppressor WT1 enhances CD95L expression and promotes activation-induced cell death in leukemic T cells.

Published in:

International Journal of Cancer, 2014, v. 134, n. 2, p. 291, doi. 10.1002/ijc.28379

By:

Bourkoula, Konstantina;
Englert, Christoph;
Giaisi, Marco;
Köhler, Rebecca;
Krammer, Peter H.;
Li ‐ Weber, Min

Publication type:

Article

Targeting the IL-4/IL-13 signaling pathway sensitizes Hodgkin lymphoma cells to chemotherapeutic drugs.

Published in:

International Journal of Cancer, 2013, v. 133, n. 8, p. 1945, doi. 10.1002/ijc.28189

By:

Natoli, Antonino;
Lüpertz, Regine;
Merz, Christian;
Müller, Wolfgang W.;
Köhler, Rebecca;
Krammer, Peter H.;
Li‐Weber, Min

Publication type:

Article

Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas.

Published in:

International Journal of Cancer, 2012, v. 131, n. 4, p. 1003, doi. 10.1002/ijc.26458

By:

Giaisi, Marco;
Köhler, Rebecca;
Fulda, Simone;
Krammer, Peter H.;
Li-Weber, Min

Publication type:

Article

Histone deacetylase inhibitor-induced sensitization to TNFα/TRAIL-mediated apoptosis in cervical carcinoma cells is dependent on HPV oncogene expression.

Published in:

International Journal of Cancer, 2010, v. 127, n. 6, p. 1384, doi. 10.1002/ijc.25170

By:

Darvas, Katalin;
Rosenberger, Simone;
Brenner, Dirk;
Fritsch, Cornelius;
Gmelin, Nadine;
Krammer, Peter H.;
Rösl, Frank

Publication type:

Article

Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway.

Published in:

International Journal of Cancer, 2010, v. 126, n. 9, p. 2049, doi. 10.1002/ijc.24861

By:

Seitz, Sarah J.;
Schleithoff, Elisa Schulze;
Koch, Andreas;
Schuster, André;
Teufel, Andreas;
Staib, Frank;
Stremmel, Wolfgang;
Melino, Gerry;
Krammer, Peter H.;
Schilling, Tobias;
Müller, Martina

Publication type:

Article

Parathyroid hormone-related protein confers chemoresistance by blocking apoptosis signaling via death receptors and mitochondria.

Published in:

International Journal of Cancer, 2009, v. 125, n. 7, p. 1551, doi. 10.1002/ijc.24471

By:

Gagiannis, Sarah;
Müller, Martina;
Uhlemann, Sebastian;
Koch, Andreas;
Melino, Gerry;
Krammer, Peter H.;
Nawroth, Peter P.;
Brune, Maik;
Schilling, Tobias

Publication type:

Article

The traditional Chinese herbal compound rocaglamide preferentially induces apoptosis in leukemia cells by modulation of mitogen-activated protein kinase activities.

Published in:

International Journal of Cancer, 2007, v. 121, n. 8, p. 1839, doi. 10.1002/ijc.22883

By:

Zhu, Jia Y.;
Lavrik, Inna N.;
Mahlknecht, Ulrich;
Giaisi, Marco;
Proksch, Peter;
Krammer, Peter H.;
Li-Weber, Min

Publication type:

Article

A New C-Terminal Cleavage Product of Procaspase-8, p30, Defines an Alternative Pathway of Procaspase-8 Activation.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 16, p. 4431, doi. 10.1128/MCB.02261-07

By:

Hoffmann, Julia C.;
Pappa, Alexander;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

Novel Role for Mitochondria: Protein Kinase Cθ-Dependent Oxidative Signaling Organelles in Activation-Induced T-Cell Death.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 10, p. 6, doi. 10.1128/MCB.02295-06

By:

Kaminki, Marcin;
Kießling, Michael;
Süss, Dorothee;
Krammer, Peter H.;
Gülow, Karsten

Publication type:

Article

Molecular Mechanisms of Death-Receptor-Mediated Apoptosis.

Published in:

ChemBioChem, 2001, v. 2, n. 1, p. 20, doi. 10.1002/1439-7633(20010105)2:1<20::AID-CBIC20>3.0.CO;2-X

By:

Sartorius, Ute;
Schmitz, Ingo;
Krammer, Peter H.

Publication type:

Article

CD4+CD25+ regulatory T cells in human lupus erythematosus.

Published in:

Archives of Dermatological Research, 2009, v. 301, n. 1, p. 71, doi. 10.1007/s00403-008-0891-9

By:

Kuhn, Annegret;
Beissert, Stefan;
Krammer, Peter H.

Publication type:

Article

An unexpected role for FosB in activation-induced cell death of T cells.

Published in:

Oncogene, 2003, v. 22, n. 9, p. 1333, doi. 10.1038/sj.onc.1206126

By:

Baumann, Sven;
Hess, Jochen;
Eichhorst, Soren T;
Krueger, Andreas;
Angel, Peter;
Krammer, Peter H;
Kirchhoff, Sabine

Publication type:

Article

Restoration of p53 expression sensitizes human papillomavirus type 16 immortalized human keratinocytes to CD95-mediated apoptosis.

Published in:

Oncogene, 2002, v. 21, n. 2, p. 165, doi. 10.1038/sj.onc.1204979

By:

Aguilar-Lemarroy, Adriana;
Gariglio, Patricio;
Whitaker, Noel J.;
Eichhorst, Soren T.;
zur Hausen, Harald;
Krammer, Peter H.;
Rosl, Frank

Publication type:

Article

CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release.

Published in:

Oncogene, 2001, v. 20, n. 31, p. 4128, doi. 10.1038/sj.onc.1204534

By:

Röhn, Till A;
Wagenknecht, Bettina;
Roth, Wilfried;
Naumann, Ulrike;
Gulbins, Erich;
Krammer, Peter H;
Walczak, Henning;
Weller, Michael

Publication type:

Article

Death ligand/receptor-independent caspase activation mediates drug-induced cytotoxic cell death in human malignant glioma cells.

Published in:

Oncogene, 1999, v. 18, n. 36, p. 5044, doi. 10.1038/sj.onc.1202882

By:

Glaser, Tamara;
Wagenknecht, Bettina;
Groscurth, Peter;
Krammer, Peter H;
Weller, Michael

Publication type:

Article

Frequency and activity of immune interferon (IFN-γ)-and colony-stimulating factor-producing human peripheral blood T lymphocytes.

Published in:

European Journal of Immunology, 1984, v. 14, n. 4, p. 368, doi. 10.1002/eji.1830140417

By:

Kees, Ursula;
Kaltmann, Brigitte;
Marcucci, Fabrizio;
Hültner, Lothar;
Staber, Fritz;
Krammer, Peter H.

Publication type:

Article

Constitutive interleukin 2 production by the JURKAT human leukemic T cell line.

Published in:

European Journal of Immunology, 1982, v. 12, n. 5, p. 387, doi. 10.1002/eji.1830120506

By:

Pawelec, Graham;
Borowitz, A.;
Krammer, Peter H.;
Wernet, Peter

Publication type:

Article

Heterogeneity of soluble T cell products I. Precursor frequency and correlation analysis of cytotoxic and immune interferon (IFN-γ)-producing spleen cells in the mouse.

Published in:

European Journal of Immunology, 1982, v. 12, n. 3, p. 200, doi. 10.1002/eji.1830120306

By:

Krammer, Peter H.;
Marcucci, Fabrizio;
Waller, Michael;
Kirchner, Holger

Publication type:

Article

Selection of bacterial mutants from Salmonella specifically recognizing determinants on the cell surface of activated T lymphocytes A novel system to define cell surface structures.

Published in:

European Journal of Immunology, 1980, v. 10, n. 9, p. 685, doi. 10.1002/eji.1830100906

By:

Lehmann, Volker;
Streck, Helmut;
Minner, Inge;
Krammer, Peter H.;
Ruschmann, Ellen

Publication type:

Article

The chains of death.

Published in:

Cell Cycle, 2013, v. 12, n. 2, p. 193, doi. 10.4161/cc.23464

By:

Schleich, Kolja;
Krammer, Peter H.;
Lavrik, Inna N.

Publication type:

Article

MAPK/ERK signaling in activated T cells inhibits CD95/Fas‐mediated apoptosis downstream of DISC assembly.

Published in:

EMBO Journal, 2000, v. 19, n. 20, p. 5418, doi. 10.1093/emboj/19.20.5418

By:

Holmström, Tim H.;
Schmitz, Ingo;
Söderström, Thomas S.;
Poukkula, Minna;
Johnson, Victoria L.;
Chow, Sek C.;
Krammer, Peter H.;
Eriksson, John E.

Publication type:

Article

MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.

Published in:

EMBO Journal, 2000, v. 19, n. 20, p. 5418, doi. 10.1093/emboj/19.20.5418

By:

Holmström, Tim H.;
Schmitz, Ingo;
Söderström, Thomas S.;
Poukkula, Minna;
Johnson, Victoria L.;
Chow, Sek C.;
Krammer, Peter H.;
Eriksson, John E.

Publication type:

Article

DEDD, a novel death effector domain-containing protein, targeted to the nucleolus.

Published in:

EMBO Journal, 1998, v. 17, n. 20, p. 5974, doi. 10.1093/emboj/17.20.5974

By:

Stegh, Alexander H.;
Schickling, Olaf;
Ehret, Andreas;
Scaffidi, Carsten;
Peterhänsel, Christoph;
Hofmann, Thomas G.;
Grummt, Ingred;
Krammer, Peter H.;
Peter, Marcus E.

Publication type:

Article

Two CD95 (APO-1/Fas) signaling pathways.

Published in:

EMBO Journal, 1998, v. 17, n. 6, p. 1675, doi. 10.1093/emboj/17.6.1675

By:

Scaffidi, Carsten;
Fulda, Simone;
Srinivasan, Anu;
Friesen, Claudia;
Feng Li;
Tomaselli, Kevin J.;
Debatin, Klaus-Michael;
Krammer, Peter H.;
Peter, Marcus E.

Publication type:

Article