Works by Kleinebudde, Peter

Results: 82

Mechanistic understanding regarding the functionality of microcrystalline cellulose and powdered cellulose as pelletization aids in wet-extrusion/spheronization.

Published in:

Cellulose, 2020, v. 27, n. 4, p. 2189, doi. 10.1007/s10570-019-02895-y

By:

Lenhart, Vincent;
Quodbach, Julian;
Kleinebudde, Peter

Publication type:

Article

Impact of roll compaction design, process parameters, and material deformation behaviour on ribbon relative density.

Published in:

Drug Development & Industrial Pharmacy, 2018, v. 44, n. 8, p. 1295, doi. 10.1080/03639045.2018.1446444

By:

Csordas, Kitti;
Wiedey, Raphael;
Kleinebudde, Peter

Publication type:

Article

Influence of drug load on dissolution behavior of tablets containing a poorly water-soluble drug: estimation of the percolation threshold.

Published in:

Drug Development & Industrial Pharmacy, 2017, v. 43, n. 8, p. 1265, doi. 10.1080/03639045.2017.1313856

By:

Wenzel, Tim;
Stillhart, Cordula;
Kleinebudde, Peter;
Szepes, Anikó

Publication type:

Article

Preparation and physicochemical characterization of matrix pellets containing APIs with different solubility via extrusion process.

Published in:

Drug Development & Industrial Pharmacy, 2017, v. 43, n. 3, p. 458, doi. 10.1080/03639045.2016.1261150

By:

Hegyesi, Diána;
Thommes, Markus;
Kleinebudde, Peter;
Sovány, Tamás;
Kása, Péter;
Kelemen, András;
Pintye-Hódi, Klára;
Regdon, Géza

Publication type:

Article

Combined application of mixture experimental design and artificial neural networks in the solid dispersion development.

Published in:

Drug Development & Industrial Pharmacy, 2016, v. 42, n. 3, p. 389, doi. 10.3109/03639045.2015.1054831

By:

Medarević, Djordje P.;
Kleinebudde, Peter;
Djuriš, Jelena;
Djurić, Zorica;
Ibrić, Svetlana

Publication type:

Article

Development of a Raman method to follow the evolution of coating thickness of pellets.

Published in:

Drug Development & Industrial Pharmacy, 2014, v. 40, n. 8, p. 1005, doi. 10.3109/03639045.2013.795583

By:

Nikowitz, Krisztina;
Folttmann, Friederike;
Wirges, Markus;
Knop, Klaus;
Pintye-Hódi, Klára;
Regdon, Géza;
Kleinebudde, Peter

Publication type:

Article

Preparing of pellets by extrusion/spheronization using different types of equipment and process conditions.

Published in:

Drug Development & Industrial Pharmacy, 2014, v. 40, n. 6, p. 762, doi. 10.3109/03639045.2013.783588

By:

Bölcskei, Éva;
Regdon, Géza;
Sovány, Tamás;
Ghanam, Dima;
Knop, Klaus;
Kleinebudde, Peter;
Pintye-Hódi, Klára

Publication type:

Article

Pellet layering: scale-up considerations using different kinds of processing equipment.

Published in:

Drug Development & Industrial Pharmacy, 2012, v. 38, n. 12, p. 1494, doi. 10.3109/03639045.2011.653815

By:

Suhrenbrock, Lisa;
Radtke, Guido;
Knop, Klaus;
Kleinebudde, Peter

Publication type:

Article

Suitability of a flat die press for the manufacture of pharmaceutical pellets by extrusion//spheronization.

Published in:

Drug Development & Industrial Pharmacy, 2011, v. 37, n. 4, p. 456, doi. 10.3109/03639045.2010.522191

By:

Ghanam, Dima;
Kleinebudde, Peter

Publication type:

Article

Feasibility of Raman spectroscopy as PAT tool in active coating.

Published in:

Drug Development & Industrial Pharmacy, 2010, v. 36, n. 2, p. 234, doi. 10.3109/03639040903225109

By:

Müller, Joshua;
Knop, Klaus;
Thies, Jochen;
Uerpmann, Carsten;
Kleinebudde, Peter

Publication type:

Article

Development of Fast-Disintegrating Pellets in a Rotary Processor.

Published in:

Drug Development & Industrial Pharmacy, 2002, v. 28, n. 10, p. 1201, doi. 10.1081/DDC-120015353

By:

Kristensen, Jakob;
Schæfer, Torben;
Kleinebudde, Peter

Publication type:

Article

Increasing the Batch Size of a QESD Crystallization by Using a MSMPR Crystallizer.

Published in:

Pharmaceutics, 2022, v. 14, n. 6, p. 1227, doi. 10.3390/pharmaceutics14061227

By:

Hansen, Jerome;
Kleinebudde, Peter

Publication type:

Article

A New Validation Methodology for In Silico Tools Based on X-ray Computed Tomography Images of Tablets and a Performance Analysis of One Tool.

Published in:

Pharmaceutics, 2021, v. 13, n. 9, p. 1488, doi. 10.3390/pharmaceutics13091488

By:

Bollmann, Sebastian;
Kleinebudde, Peter

Publication type:

Article

Evaluation of Binders in Twin-Screw Wet Granulation.

Published in:

Pharmaceutics, 2021, v. 13, n. 2, p. 241, doi. 10.3390/pharmaceutics13020241

By:

Köster, Claudia;
Pohl, Sebastian;
Kleinebudde, Peter;
Vanhoorne, Valérie

Publication type:

Article

Raman Spectroscopy as a PAT-Tool for Film-Coating Processes: In-Line Predictions Using one PLS Model for Different Cores.

Published in:

Pharmaceutics, 2020, v. 12, n. 9, p. 796, doi. 10.3390/pharmaceutics12090796

By:

Radtke, Juliana;
Rehbaum, Hubertus;
Kleinebudde, Peter

Publication type:

Article

Predictive Model-Based Process Start-Up in Pharmaceutical Continuous Granulation and Drying.

Published in:

Pharmaceutics, 2020, v. 12, n. 1, p. 67, doi. 10.3390/pharmaceutics12010067

By:

Pauli, Victoria;
Kleinebudde, Peter;
Krumme, Markus

Publication type:

Article

Compaction Behavior of Isomalt after Roll Compaction.

Published in:

Pharmaceutics, 2012, v. 4, n. 4, p. 494, doi. 10.3390/pharmaceutics4040494

By:

Quodbach, Julian;
Mosig, Johanna;
Kleinebudde, Peter

Publication type:

Article

From Mini to Micro Scale—Feasibility of Raman Spectroscopy as a Process Analytical Tool (PAT).

Published in:

Pharmaceutics, 2011, v. 3, n. 4, p. 723, doi. 10.3390/pharmaceutics3040723

By:

Wirges, Markus;
Müller, Joshua;
Kása Jr., Péter;
Regdon Jr., Géza;
Pintye-Hódi, Klára;
Knop, Klaus;
Kleinebudde, Peter

Publication type:

Article

Towards a better understanding of the role of stabilizers in QESD crystallizations.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 12, p. 3123, doi. 10.1007/s11095-022-03212-2

By:

Hansen, Jerome;
Kleinebudde, Peter

Publication type:

Article

Effect of roll compaction on granule size distribution of microcrystalline cellulose--mannitol mixtures: computational intelligence modeling and parametric analysis.

Published in:

Drug Design, Development & Therapy, 2017, v. 11, p. 241, doi. 10.2147/DDDT.S124670

By:

Kazemi, Pezhman;
Khalid, Mohammad Hassan;
Gago, Ana Pérez;
Kleinebudde, Peter;
Jachowicz, Renata;
Szlęk, Jakub;
Mendyk, Aleksander

Publication type:

Article

Correction: Croscarmellose Sodium as Pelletization Aid in Extrusion-Spheronization.

Published in:

2024

By:

Siebel, Finn;
Kleinebudde, Peter

Publication type:

Correction Notice

Croscarmellose Sodium as Pelletization Aid in Extrusion-Spheronization.

Published in:

AAPS PharmSciTech, 2024, v. 25, n. 6, p. 1, doi. 10.1208/s12249-024-02864-0

By:

Siebel, Finn;
Kleinebudde, Peter

Publication type:

Article

Evaluation of In-Die Compression Data for a Deeper Understanding of Altered Excipient Properties upon Temperature Rise.

Published in:

AAPS PharmSciTech, 2023, v. 24, n. 4, p. 1, doi. 10.1208/s12249-023-02554-3

By:

Grumann, Hanna Dorothea;
Klinken, Stefan;
Kleinebudde, Peter

Publication type:

Article

Fibrillated Cellulose via High Pressure Homogenization: Analysis and Application for Orodispersible Films.

Published in:

AAPS PharmSciTech, 2020, v. 21, n. 1, p. 1, doi. 10.1208/s12249-019-1593-7

By:

Lenhart, Vincent;
Quodbach, Julian;
Kleinebudde, Peter

Publication type:

Article

Roll Compaction and Tableting of High Loaded Metformin Formulations Using Efficient Binders.

Published in:

AAPS PharmSciTech, 2018, v. 19, n. 5, p. 2068, doi. 10.1208/s12249-018-1012-5

By:

Arndt, Oscar-Rupert;
Kleinebudde, Peter

Publication type:

Article

Development of a New Dissolution Test Method for Soft Chewable Dosage Forms.

Published in:

AAPS PharmSciTech, 2017, v. 18, n. 7, p. 2446, doi. 10.1208/s12249-017-0729-x

By:

Stomberg, Carmen;
Kanikanti, Venkata-Rangarao;
Hamann, Hans-Jürgen;
Kleinebudde, Peter

Publication type:

Article

Experimental Analysis of Tablet Properties for Discrete Element Modeling of an Active Coating Process.

Published in:

AAPS PharmSciTech, 2013, v. 14, n. 1, p. 402, doi. 10.1208/s12249-013-9925-5

By:

Just, Sarah;
Toschkoff, Gregor;
Funke, Adrian;
Djuric, Dejan;
Scharrer, Georg;
Khinast, Johannes;
Knop, Klaus;
Kleinebudde, Peter

Publication type:

Article

From Heuristic to Mathematical Modeling of Drugs Dissolution Profiles: Application of Artificial Neural Networks and Genetic Programming.

Published in:

Computational & Mathematical Methods in Medicine, 2015, v. 2015, p. 1, doi. 10.1155/2015/863874

By:

Mendyk, Aleksander;
Güres, Sinan;
Jachowicz, Renata;
Szlęk, Jakub;
Polak, Sebastian;
Wiśniowska, Barbara;
Kleinebudde, Peter

Publication type:

Article

Simplified, High Drug-Loaded Formulations Containing Hydrochlorothiazide for Twin-Screw Granulation.

Published in:

Chemie Ingenieur Technik (CIT), 2017, v. 89, n. 8, p. 1025, doi. 10.1002/cite.201600134

By:

Meier, Robin;
Moll, Klaus‐Peter;
Krumme, Markus;
Kleinebudde, Peter

Publication type:

Article

The Density Distribution in Ribbons from Roll Compaction.

Published in:

Chemie Ingenieur Technik (CIT), 2017, v. 89, n. 8, p. 1017, doi. 10.1002/cite.201600143

By:

Wiedey, Raphael;
Kleinebudde, Peter

Publication type:

Article

Pharmazeutisches Produktdesign: Gezielte Freisetzung von Wirkstoffen durch unterschiedliche Extrusionstechniken.

Published in:

Chemie Ingenieur Technik (CIT), 2011, v. 83, n. 5, p. 589, doi. 10.1002/cite.201000162

By:

Kleinebudde, Peter

Publication type:

Article

Improvement of Dissolution Behavior for Poorly Water-Soluble Drug by Application of Cyclodextrin in Extrusion Process: Comparison between Melt Extrusion and Wet Extrusion.

Published in:

AAPS PharmSciTech, 2010, v. 11, n. 2, p. 885, doi. 10.1208/s12249-010-9448-2

By:

Yano, Hideki;
Kleinebudde, Peter

Publication type:

Article

Investigating the Principles of Recrystallization from Glyceride Melts.

Published in:

AAPS PharmSciTech, 2009, v. 10, n. 4, p. 1224, doi. 10.1208/s12249-009-9311-5

By:

Windbergs, Maike;
Strachan, Clare;
Kleinebudde, Peter

Publication type:

Article

The 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology (PBP Meeting) April 7–10, 2008, Barcelona, Spain.

Published in:

2008

By:

Kleinebudde, Peter;
Alex, Rainer;
Fattal, Elias;
Göpferich, Achim;
Siepmann, Jürgen

Publication type:

Report

Properties of pellets manufactured by wet extrusion/spheronization process using κ-carrageenan: Effect of process parameters.

Published in:

AAPS PharmSciTech, 2007, v. 8, n. 4, p. 101, doi. 10.1208/pt0804095

By:

Thommes, Markus;
Kleinebudde, Peter

Publication type:

Article

Influence of chitosan type on the properties of extruded pellets with low amount of microcrystalline cellulose.

Published in:

AAPS PharmSciTech, 2007, v. 8, n. 3, p. E99, doi. 10.1208/pt0803064

By:

Charoenthai, Nattawut;
Kleinebudde, Peter;
Puttipipatkhachorn, Satit

Publication type:

Article

Comparison of a laboratory and a production coating spray gun with respect to scale-up.

Published in:

AAPS PharmSciTech, 2007, v. 8, n. 1, p. E21, doi. 10.1208/pt0801003

By:

Mueller, Ronny;
Kleinebudde, Peter

Publication type:

Article

Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater: Part 2: Application of the model.

Published in:

AAPS PharmSciTech, 2006, v. 7, n. 2, p. E87, doi. 10.1208/pt070243

By:

Page, Susanne;
Baumann, Karl-Heinrich;
Kleinebudde, Peter

Publication type:

Article

Mathematical modeling of an aqueous film coating process in a Bohle Lab-Coater, Part 1: Development of the model.

Published in:

AAPS PharmSciTech, 2006, v. 7, n. 2, p. E79, doi. 10.1208/pt070242

By:

Page, Susanne;
Baumann, Karl-Heinrich;
Kleinebudde, Peter

Publication type:

Article

Extrusion/spheronization of pectin-based formulations. II. Effect of additive concentration in the granulation liquid.

Published in:

AAPS PharmSciTech, 2001, v. 2, n. 4, p. 63, doi. 10.1208/pt020427

By:

Tho, Ingunn;
Kleinebudde, Peter;
Sande, Sverre

Publication type:

Article

Extrusion/spheronization of pectin-based formulations. I. Screening of important factors.

Published in:

AAPS PharmSciTech, 2001, v. 2, n. 4, p. 54, doi. 10.1208/pt020426

By:

Tho, Ingunn;
Kleinebudde, Peter;
Sande, Sverre

Publication type:

Article

Direct pelletization in a rotary processor controlled by torque measurements. II: Effects of changes in the content of microcrystalline cellulose.

Published in:

AAPS Journal, 2000, v. 2, n. 3, p. 45, doi. 10.1208/ps020324

By:

Kristensen, Jakob;
Schæfer, Torben;
Kleinebudde, Peter

Publication type:

Article

Influence of degree of polymerization on behavior of cellulose during homogenization and extrusion/spheronization.

Published in:

AAPS Journal, 2000, v. 2, n. 3, p. 18, doi. 10.1208/ps020321

By:

Kleinebudde, Peter;
Jumaa, Muhannad;
Saleh, Firas

Publication type:

Article

Continuous Single-Step Wet Granulation with Integrated in-Barrel-Drying.

Published in:

Pharmaceutical Research, 2018, v. 35, n. 8, p. 1, doi. 10.1007/s11095-018-2451-0

By:

Schmidt, Adrian;
de Waard, Hans;
Kleinebudde, Peter;
Krumme, Markus

Publication type:

Article

Comparison of the Performance of Single Punch and Rotary Tablet Presses from Different Vendors.

Published in:

TechnoPharm, 2018, v. 8, n. 2, p. 96

By:

Zimmermann, Maren;
Schaldach, Gerhard;
Thommes, Markus;
Bauer-Brandl, Annette;
Kleinebudde, Peter

Publication type:

Article

Vereine fördern die Bestrebungen ihrer Mitglieder und stören die der anderen.

Published in:

2003

By:

Kleinebudde, Peter

Publication type:

Editorial

Editorial.

Published in:

Pharmazeutische Industrie (Pharmind), 2003, v. 65, n. 6, p. 4

By:

Kleinebudde, Peter

Publication type:

Article

'Es gibt nichts Gutes, auΒer man tut es.'

Published in:

2003

By:

Kleinebudde, Peter

Publication type:

Editorial

Encapsulation of orange terpenes investigating a plasticisation extrusion process.

Published in:

Journal of Microencapsulation, 2015, v. 32, n. 4, p. 408, doi. 10.3109/02652048.2015.1035686

By:

Tackenberg, Markus W.;
Krauss, Ralph;
Schuchmann, Heike P.;
Kleinebudde, Peter

Publication type:

Article

Influence of Water on Molecular and Morphological Structure of Various Starches and Starch Derivatives.

Published in:

Starch / Staerke, 2005, v. 57, n. 12, p. 605, doi. 10.1002/star.200500410

By:

Petra M. Fechner;
Siegfried Wartewig;
Andreas Kiesow;
Andreas Heilmann;
Peter Kleinebudde;
Reinhard H. H. Neubert

Publication type:

Article