Works by Kirschner, Daniel A.

Results: 41

Poly-( L-alanine) expansions form core β-sheets that nucleate amyloid assembly.

Published in:

Proteins, 2005, v. 61, n. 3, p. 579, doi. 10.1002/prot.20536

By:

Shinchuk, Leonid M.;
Sharma, Deepak;
Blondelle, Sylvie E.;
Reixach, Natalia;
Inouye, Hideyo;
Kirschner, Daniel A.

Publication type:

Article

Polyglutamine homopolymers having 8-45 residues form slablike β-crystallite assemblies.

Published in:

Proteins, 2005, v. 61, n. 2, p. 398, doi. 10.1002/prot.20602

By:

Sharma, Deepak;
Shinchuk, Leonid M.;
Inouye, Hideyo;
Wetzel, Ronald;
Kirschner, Daniel A.

Publication type:

Article

Constitutively Active Akt Induces Enhanced Myelination in the CNS.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 28, p. 7174, doi. 10.1523/JNEUROSCI.0150-08.2008

By:

Flores, Ana I.;
Narayanan, S. Priyadarshini;
Morse, Emily N.;
Shick, H. Elizabeth;
Xinghua Yin;
Kidd, Grahame;
Avila, Robin L.;
Kirschner, Daniel A.;
Macklin, Wendy B.

Publication type:

Article

Different Intracellular Pathomechanisms Produce Diverse Myelin Protein Zero Neuropathies in Transgenic Mice.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 8, p. 2358, doi. 10.1523/JNEUROSCI.3819-05.2006

By:

Wrabetz, Lawrence;
D'Antonio, Maurizio;
Pennuto, Maria;
Dati, Gabriele;
Tinelli, Elisa;
Fratta, Pietro;
Previtali, Stefano;
Imperiale, Daniele;
Zielasek, Jurgen;
Toyka, Klaus;
Avila, Robin L.;
Kirschner, Daniel A.;
Messing, Albee;
Feltri, M. Laura;
Quattrini, Angelo

Publication type:

Article

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination.

Published in:

2014

By:

da Silva, Tiago Ferreira;
Eira, Jessica;
Lopes, André T;
Malheiro, Ana R;
Sousa, Vera;
Luoma, Adrienne;
Avila, Robin L;
Wanders, Ronald J A;
Just, Wilhelm W;
Kirschner, Daniel A;
Sousa, Mónica M;
Brites, Pedro

Publication type:

journal article

Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2560, doi. 10.1172/JCI72063

By:

da Silva, Tiago Ferreira;
Eira, Jessica;
Lopes, André T.;
Malheiro, Ana R.;
Sousa, Vera;
Luoma, Adrienne;
Avila, Robin L.;
Wanders, Ronald J. A.;
Just, Wilhelm W.;
Kirschner, Daniel A.;
Sousa, Mónica M.;
Brites, Pedro

Publication type:

Article

Fine-Structure and Supramolecular Organization of the Radial Component of CNS Myelina.

Published in:

Annals of the New York Academy of Sciences, 1990, v. 605, n. 1, p. 430, doi. 10.1111/j.1749-6632.1990.tb42437.x

By:

KOSARAS, BÉLA;
KIRSCHNER, DANIEL A.

Publication type:

Article

Evolution of a neuroprotective function of central nervous system myelin.

Published in:

Journal of Cell Biology, 2006, v. 172, n. 3, p. 469, doi. 10.1083/jcb.200509174

By:

Yin, Xinghua;
Baek, Rena C.;
Kirschner, Daniel A.;
Peterson, Alan;
Fujii, Yasuhisa;
Nave, Klaus-Armin;
Macklin, Wendy B.;
Trapp, Bruce D.

Publication type:

Article

Myelin Structure and Composition in Zebrafish.

Published in:

Neurochemical Research, 2007, v. 32, n. 2, p. 211, doi. 10.1007/s11064-007-9280-6

By:

Robin Avila;
Brian Tevlin;
Jonathan Lees;
Hideyo Inouye;
Daniel Kirschner

Publication type:

Article

Myelin Structure and Composition in Zebrafish.

Published in:

Neurochemical Research, 2007, v. 32, n. 2, p. 197, doi. 10.1007/s11064-006-9136-5

By:

Robin Avila;
Brian Tevlin;
Jonathan Lees;
Hideyo Inouye;
Daniel Kirschner

Publication type:

Article

Lack of Collagen XV Impairs Peripheral Nerve Maturation and, When Combined with Laminin-41 1 Deficiency, Leads to Basement Membrane Abnormalities and Sensorimotor Dysfunction.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 43, p. 14490, doi. 10.1523/JNEUROSCI.2644-10.2010

By:

Rasi, Karolina;
Hurskainen, Merja;
Kallio, Mika;
Stavén, Saara;
Sormunen, Raija;
Heape, Anthony M.;
Avila, Robin L.;
Kirschner, Daniel;
Muona, Anu;
Tolonen, Uolevi;
Tanila, Heikki;
Huhtala, Pirkko;
Soininen, Raija;
Pihiajaniemi, Taina

Publication type:

Article

Histidine residues underlie Congo red binding to Aβ analogs.

Published in:

Amyloid, 2000, v. 7, n. 3, p. 179, doi. 10.3109/13506120009146832

By:

Inouye, Hideyo;
Nguyen, Jack T.;
Fraser, Paul E.;
Shinchuk, Leonid M.;
Packard, Alan B.;
Kirschner, Daniel A.

Publication type:

Article

Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament.

Published in:

Amyloid, 1998, v. 5, n. 3, p. 163, doi. 10.3109/13506129809003842

By:

Inouye, Hideyo;
Domingue, Francisco S.;
Damas, Ana M.;
Saraiva, Maria J.;
Lundgren, Erik;
Sandgren, Ola;
Kirschner, Daniel A.

Publication type:

Article

Differential effects of phe19 and phe20 on fibril formation by amyloidogenic peptide Aβ16-22 (Ac-KLVFFAE-NH2).

Published in:

Proteins, 2010, v. 78, n. 10, p. 2306, doi. 10.1002/prot.22743

By:

Inouye, Hideyo;
Gleason, Katherine A.;
Zhang, Dong;
Decatur, Sean M.;
Kirschner, Daniel A.

Publication type:

Article

Arctic ground squirrel hippocampus tolerates oxygen glucose deprivation independent of hibernation season even when not hibernating and after ATP depletion, acidosis, and glutamate efflux.

Published in:

Journal of Neurochemistry, 2017, v. 142, n. 1, p. 160, doi. 10.1111/jnc.13996

By:

Bhowmick, Saurav;
Moore, Jeanette T.;
Kirschner, Daniel L.;
Drew, Kelly L.

Publication type:

Article

A Single Intravenous rAAV Injection as Late as P20 Achieves Efficacious and Sustained CNS Gene Therapy in Canavan Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2136, doi. 10.1038/mt.2013.138

By:

Ahmed, Seemin Seher;
Li, Huapeng;
Cao, Chunyan;
Sikoglu, Elif M;
Denninger, Andrew R;
Su, Qin;
Eaton, Samuel;
Liso Navarro, Ana A;
Xie, Jun;
Szucs, Sylvia;
Zhang, Hongwei;
Moore, Constance;
Kirschner, Daniel A;
Seyfried, Thomas N;
Flotte, Terence R;
Matalon, Reuben;
Gao, Guangping

Publication type:

Article

The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38645-0

By:

Snow, Alan D.;
Castillo, Gerardo M.;
Nguyen, Beth P.;
Choi, Paula Y.;
Cummings, Joel A.;
Cam, Judy;
Hu, Qubai;
Lake, Thomas;
Pan, Weihong;
Kastin, Abba J.;
Kirschner, Daniel A.;
Wood, Steven G.;
Rockenstein, Edward;
Masliah, Eliezer;
Lorimer, Stephen;
Tanzi, Rudolph E.;
Larsen, Lesley

Publication type:

Article

Myelin P0-Glycoprotein: Predicted Structure and Interactions of Extracellular Domain.

Published in:

Journal of Neurochemistry, 1993, v. 61, n. 6, p. 1987, doi. 10.1111/j.1471-4159.1993.tb07434.x

By:

Wells, Christopher A.;
Saavedra, Raul A.;
Inouye, Hideyo;
Kirschner, Daniel A.

Publication type:

Article

α1-Antichymotrypsin Binding to Alzheimer Aβ Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro.

Published in:

Journal of Neurochemistry, 1993, v. 61, n. 1, p. 298, doi. 10.1111/j.1471-4159.1993.tb03568.x

By:

Fraser, Paul E.;
Nguyen, Jack T.;
McLachlan, Donald R.;
Abraham, Carmela R.;
Kirschner, Daniel A.

Publication type:

Article

Effects of Sulfate Ions on Alzheimer β/A4 Peptide Assemblies: Implications for Amyloid Fibril-Proteoglycan Interactions.

Published in:

Journal of Neurochemistry, 1992, v. 59, n. 4, p. 1531, doi. 10.1111/j.1471-4159.1992.tb08470.x

By:

Fraser, Paul E.;
Nguyen, Jack T.;
Chin, David T.;
Kirschner, Daniel A.

Publication type:

Article

Myelin Membrane Structure and Composition Correlated: A Phylogenetic Study.

Published in:

Journal of Neurochemistry, 1989, v. 53, n. 5, p. 1599, doi. 10.1111/j.1471-4159.1989.tb08558.x

By:

Kirschner, Daniel A.;
Inouye, Hideyo;
Ganser, Allen L.;
Mann, Vicki

Publication type:

Article

Membrane Interactions Are Altered in Myelin Isolated from Central and Peripheral Nervous System Tissues.

Published in:

Journal of Neurochemistry, 1988, v. 51, n. 1, p. 228, doi. 10.1111/j.1471-4159.1988.tb04860.x

By:

Karthigasan, Jeevajothie;
Kirschner, Daniel A.

Publication type:

Article

Shiverer and Normal Peripheral Myelin Compared: Basic Protein Localization, Membrane Interactions, and Lipid Composition.

Published in:

Journal of Neurochemistry, 1985, v. 45, n. 6, p. 1911, doi. 10.1111/j.1471-4159.1985.tb10551.x

By:

Inouye, Hideyo;
Ganser, Allen L.;
Kirschner, Daniel A.

Publication type:

Article

Myelin Membrane from Adrenoleukodystrophy Brain White Matter-Biochemical Properties.

Published in:

Journal of Neurochemistry, 1983, v. 41, n. 2, p. 341, doi. 10.1111/j.1471-4159.1983.tb04748.x

By:

Brown, Frank R.;
Chen, Winston W.;
Kirschner, Daniel A.;
Frayer, Karen L.;
Powers, James M.;
Moser, Ann B.;
Moser, Hugo W.

Publication type:

Article

Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis.

Published in:

Journal of Negative Results in Biomedicine, 2007, v. 6, p. 8, doi. 10.1186/1477-5751-6-8

By:

McNally, Melanie A.;
Baek, Rena C.;
Avila, Robin L.;
Seyfried, Thomas N.;
Strichartz, Gary R.;
Kirschner, Daniel A.

Publication type:

Article

Cotinine Reduces Amyloid-β Aggregation and Improves Memory in Alzheimer's Disease Mice.

Published in:

Journal of Alzheimer's Disease, 2011, v. 24, n. 4, p. 817, doi. 10.3233/JAD-2011-102136

By:

Echeverria, Valentina;
Zeitlin, Ross;
Burgess, Sarah;
Patel, Sagar;
Barman, Arghya;
Thakur, Garima;
Mamcarz, Magorzota;
Li Wang;
Sattelle, David B.;
Kirschner, Daniel A.;
Mori, Takashi;
Leblanc, Roger M.;
Prabhakar, Rajeev;
Arendash, Gary W.

Publication type:

Article

Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 12, p. 3551

By:

Patzkó, Ágnes;
Bai, Yunhong;
Saporta, Mario A.;
Katona, István;
Wu, XingYao;
Vizzuso, Domenica;
Feltri, M. Laura;
Wang, Suola;
Dillon, Lisa M.;
Kamholz, John;
Kirschner, Daniel;
Sarkar, Fazlul H.;
Wrabetz, Lawrence;
Shy, Michael E.

Publication type:

Article

Phylogenetically Conserved Amino Acids of MBP and P0 from Amphibian Myelin.

Published in:

Journal of Molecular Neuroscience, 1992, v. 3, n. 4, p. 185, doi. 10.1007/BF03380137

By:

Karthigasan, Jeevajothie;
Bauer, Tamara;
Teplow, David;
Saavedra, Raul;
Kirschner, Daniel

Publication type:

Article

Exploiting Sphingo- and Glycerophospholipid Impairment to Select Effective Drugs and Biomarkers for CMT1A.

Published in:

Frontiers in Neurology, 2020, p. N.PAG, doi. 10.3389/fneur.2020.00903

By:

Visigalli, Davide;
Capodivento, Giovanna;
Basit, Abdul;
Fernández, Roberto;
Hamid, Zeeshan;
Pencová, Barbora;
Gemelli, Chiara;
Marubbi, Daniela;
Pastorino, Cecilia;
Luoma, Adrienne M.;
Riekel, Christian;
Kirschner, Daniel A.;
Schenone, Angelo;
Fernández, José A.;
Armirotti, Andrea;
Nobbio, Lucilla

Publication type:

Article

Myelin Organization in the Nodal, Paranodal, and Juxtaparanodal Regions Revealed by Scanning X-Ray Microdiffraction.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100592

By:

Inouye, Hideyo;
Liu, Jiliang;
Makowski, Lee;
Palmisano, Marilena;
Burghammer, Manfred;
Riekel, Christian;
Kirschner, Daniel A.

Publication type:

Article

Water diffusion, T2, and compartmentation in frog sciatic nerve.

Published in:

Magnetic Resonance in Medicine, 1999, v. 42, n. 5, p. 911, doi. 10.1002/(SICI)1522-2594(199911)42:5<911::AID-MRM11>3.0.CO;2-J

By:

Peled, Sharon;
Cory, David G.;
Raymond, Stephen A.;
Kirschner, Daniel A.;
Jolesz, Ferenc A.

Publication type:

Article

NPT001: A candidate therapeutic for clearance of β-amyloid and tau aggregates in Alzheimer's disease

Published in:

2011

By:

Fisher, Richard;
Gannon, Kimberley;
Krishnan, Rajaraman;
Tsubery, Haim;
Masliah, Eliezer;
Rockenstein, Edward;
Kirschner, Daniel;
Inouye, Hideyo;
Myszka, David;
Cirrito, John;
Green, Kim;
Wright, Jason;
Solomon, Jonathan;
LaFerla, Frank;
Solomon, Beka

Publication type:

Abstract

Cotinine: A dual-action drug with multiple benefits against Alzheimer's disease

Published in:

2010

By:

Echeverria, Valentina;
Burgess, Sarah;
Zeitlin, Ross;
Barman, Arghya;
Thakur, Garima;
Inouye, Hideyo;
Feris, Edmundo;
Buckingham, Steven;
Kirschner, Daniel;
Mori, Takashi;
Leblanc, Roger;
Prabhakar, Rajeev;
Sattelle, David;
Arendash, Gary

Publication type:

Abstract

Biophysical characterization of scyllo-inositol-Aβ interactions

Published in:

2009

By:

McLaurin, JoAnne;
Shaw, James;
Nemieboka, Noble;
Koellhoeffer, Edward;
Inouye, Hideyo;
Kirschner, Daniel;
Yang, Austin

Publication type:

Abstract

O3-05-01: A novel approach to screening inhibitors of amyloid formation

Published in:

2008

By:

Kirschner, Daniel A.;
Inouye, Hideyo;
Decatur, Sean M.

Publication type:

Abstract

Myelin Abnormalities in the Optic and Sciatic Nerves in Mice With GM1-Gangliosidosis.

Published in:

ASN Neuro, 2015, v. 7, n. 1, p. 1, doi. 10.1177/1759091415568913

By:

Heinecke, Karie A.;
Luoma, Adrienne;
d'Azzo, Alessandra;
Kirschner, Daniel A.;
Seyfried, Thomas N.

Publication type:

Article

Jimpy 4J: A New X-Linked Mouse Mutation Producing Severe CNS Hypomyelination (Part 1 of 2).

Published in:

Developmental Neuroscience, 1995, v. 17, n. 5/6, p. 300, doi. 10.1159/000111300

By:

Billings-Gagliardi, Susan;
Kirschner, Daniel A.;
Nadon, Nancy L.;
DiBenedetto, Lynn M.;
Karthigasan, Jeevajothie;
Lane, Priscilla;
Pearsall, Gail B.;
Wolf, Merrill K.

Publication type:

Article

Shiverer*jimpy Double Mutant Mice.

Published in:

Developmental Neuroscience, 1991, v. 13, n. 3, p. 138, doi. 10.1159/000112151

By:

Sinclair, Alison;
Raz, Yael;
Kirschner, Daniel A.;
Villa-Komaroff, Lydia;
Wolf, Merrill K.;
Billings-Gagliardi, Susan

Publication type:

Article

A Survey of Neurological Mutant Mice. pp 99-109.

Published in:

Developmental Neuroscience, 1988, v. 10, n. 2, p. 99, doi. 10.1159/000111961

By:

Ganser, Allen L.;
Kerner, Ann-Louise;
Brown, BettyJane;
Davisson, Muriel T.;
Kirschner, Daniel A.

Publication type:

Article

A Survey of Neurological Mutant Mice. pp 110-122.

Published in:

Developmental Neuroscience, 1988, v. 10, n. 2, p. 110, doi. 10.1159/000111962

By:

Ganser, Allen L.;
Kerner, Ann-Louise;
Brown, BettyJane;
Davisson, Muriel T.;
Kirschner, Daniel A.

Publication type:

Article

A Survey of Neurological Mutant Mice.

Published in:

Developmental Neuroscience, 1988, v. 10, n. 2, p. 123, doi. 10.1159/000111963

By:

Ganser, Allen L.;
Kerner, Ann-Louise;
Brown, BettyJane;
Davisson, Muriel T.;
Kirschner, Daniel A.

Publication type:

Article