Works by Kagechika, Hiroyuki
Results: 69
Pharmacophore-guided repurposing of fibrates and retinoids as GPR40 allosteric ligands with activity on insulin release.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 377, doi. 10.1080/14756366.2020.1864629
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- Article
An N-Cyanoamide Derivative of Lithocholic Acid Co-Operates with Lysophosphatidic Acid to Promote Human Osteoblast (MG63) Differentiation.
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- Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1113, doi. 10.3390/biom13071113
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- Article
Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists.
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- Biomolecules (2218-273X), 2022, v. 12, n. 1, p. 130, doi. 10.3390/biom12010130
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- Article
Targeting transglutaminase 2 mediated exostosin glycosyltransferase 1 signaling in liver cancer stem cells with acyclic retinoid.
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- Cell Death & Disease, 2023, v. 14, n. 6, p. 1, doi. 10.1038/s41419-023-05847-4
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- Article
13- cis-retinoic acid alters the cellular morphology of slice-cultured serotonergic neurons in the rat.
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- European Journal of Neuroscience, 2008, v. 27, n. 9, p. 2363, doi. 10.1111/j.1460-9568.2008.06191.x
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- Article
Characterization of a novel compound that promotes myogenesis via Akt and transcriptional co-activator with PDZ-binding motif (TAZ) in mouse C2C12 cells.
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- PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231265
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- Article
A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers.
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- EMBO Journal, 1997, v. 16, n. 18, p. 5697, doi. 10.1093/emboj/16.18.5697
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- Article
Synthesis of Vitamin E Analogues: Possible Active Forms of Vitamin E.
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- Archiv der Pharmazie, 1996, v. 329, n. 1, p. 27, doi. 10.1002/ardp.19963290106
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- Article
Conformational and Chiral Properties of Cyclic-tri( N-methyl- meta-benzamide) Bearing Amidino Groups.
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- Chirality, 2015, v. 27, n. 8, p. 487, doi. 10.1002/chir.22476
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- Article
Synthesis of soluble aromatic multilayered tetra( m-phenylurea) and analysis of its helical conformation in various solvents.
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- Chirality, 2011, v. 23, n. 1E, p. E84, doi. 10.1002/chir.21010
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- Article
A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47354-7
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- Article
The transcription factors Nur77 and retinoid X receptors participate in amphetamine-induced locomotor activities.
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- Psychopharmacology, 2009, v. 202, n. 4, p. 635, doi. 10.1007/s00213-008-1343-0
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- Article
Identifying the receptor subtype selectivity of retinoid X and retinoic acid receptors via quantum mechanics.
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- FEBS Open Bio, 2017, v. 7, n. 3, p. 391, doi. 10.1002/2211-5463.12188
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- Article
Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.
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- 2018
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- journal article
Prostaglandin E<sub>2</sub> and its receptor EP2 trigger signaling that contributes to YAP‐mediated cell competition.
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- Genes to Cells, 2020, v. 25, n. 3, p. 197, doi. 10.1111/gtc.12750
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- Article
Retinoid X receptor gamma signaling accelerates CNS remyelination.
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- Nature Neuroscience, 2011, v. 14, n. 1, p. 45, doi. 10.1038/nn.2702
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- Article
Docking simulations suggest that all- trans retinoic acid could bind to retinoid X receptors.
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- Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 10, p. 975, doi. 10.1007/s10822-015-9869-9
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- Article
Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy.
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- Biochemical Journal, 2013, v. 455, n. 3, p. 339, doi. 10.1042/BJ20130597
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- Article
Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon.
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- Nature Communications, 2014, v. 5, n. 11, p. 5494, doi. 10.1038/ncomms6494
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- Article
Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression.
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- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0141960
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- Article
A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis.
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- PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145286
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- Article
STAT5a/PPARγ Pathway Regulates Involucrin Expression in Keratinocyte Differentiation.
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- Journal of Investigative Dermatology, 2007, v. 127, n. 7, p. 1728, doi. 10.1038/sj.jid.5700758
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- Article
Neuritogenic activity of a genipin derivative in retinal ganglion cells is mediated by retinoic acid receptor β expression through nitric oxide/ S-nitrosylation signaling.
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- Journal of Neurochemistry, 2011, v. 119, n. 6, p. 1232, doi. 10.1111/j.1471-4159.2011.07533.x
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- Article
Effects of retinoic acids on the dendritic morphology of cultured hippocampal neurons.
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- Journal of Neurochemistry, 2008, v. 106, n. 3, p. 1104, doi. 10.1111/j.1471-4159.2008.05445.x
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- Publication type:
- Article
Specific Uptake of Retinoids into Human Promyelocytic Leukemia Cells HL-60 by Retinoid-specific Binding Protein: Possibly the True Retinoid Receptor.
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- Cancer Science, 1988, v. 79, n. 4, p. 473, doi. 10.1111/j.1349-7006.1988.tb01616.x
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- Article
Calix[3]amide-based anion receptors: high affinity for fluoride ions and a twisted binding model.
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- Supramolecular Chemistry, 2011, v. 23, n. 1/2, p. 125, doi. 10.1080/10610278.2010.514909
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- Publication type:
- Article
Peroxisome proliferator-activated receptor γ ligands stimulate myeloid differentiation and lipogenensis in human leukemia NB4 cells.
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- Development, Growth & Differentiation, 2006, v. 48, n. 3, p. 177, doi. 10.1111/j.1440-169X.2006.00855.x
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- Publication type:
- Article
ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-01123-7
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- Publication type:
- Article
ASKA technology-based pull-down method reveals a suppressive effect of ASK1 on the inflammatory NOD-RIPK2 pathway in brown adipocytes.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-01123-7
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- Article
Construction of Aromatic Multilayered Structures Based on the Conformational Properties of N,N'‐Dimethylated Squaramide.
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- ChemPlusChem, 2021, v. 86, n. 1, p. 198, doi. 10.1002/cplu.202000678
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- Article
A Polarity‐Sensitive Fluorescent Amino Acid and its Incorporation into Peptides for the Ratiometric Detection of Biomolecular Interactions.
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- ChemPlusChem, 2019, v. 84, n. 11, p. 1716, doi. 10.1002/cplu.201900489
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- Article
Amarastelline A: A Fluorescent Alkaloid from Quassia amara and Its Properties in Living Cells.
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- ChemPlusChem, 2012, v. 77, n. 6, p. 427, doi. 10.1002/cplu.201200016
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- Article
AKAPs-PKA disruptors increase AQP2 activity independently of vasopressin in a model of nephrogenic diabetes insipidus.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03771-2
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- Article
Selective Reagent for Detection of N-ε-Monomethylation of a Peptide Lysine Residue through S<sub>N</sub>Ar Reaction.
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- European Journal of Organic Chemistry, 2017, v. 2017, n. 25, p. 3606, doi. 10.1002/ejoc.201700488
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- Article
Chemical compounds that suppress hypoxia-induced stress granule formation enhance cancer drug sensitivity of human cervical cancer HeLa cells.
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- Journal of Biochemistry, 2018, v. 164, n. 5, p. 381, doi. 10.1093/jb/mvy062
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- Article
A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
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- Journal of Biochemistry, 2015, v. 158, n. 5, p. 413, doi. 10.1093/jb/mvv051
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- Article
ApoC-III gene expression is sharply increased during adipogenesis and is augmented by retinoid X receptor (RXR) agonists
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- FEBS Letters, 2009, v. 583, n. 2, p. 493, doi. 10.1016/j.febslet.2008.12.050
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- Publication type:
- Article
Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass.
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- FASEB Journal, 2015, v. 29, n. 2, p. 671, doi. 10.1096/fj.14-256743
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- Article
The mevalonate pathway regulates primitive streak formation via protein farnesylation.
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- Scientific Reports, 2016, p. 37697, doi. 10.1038/srep37697
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- Publication type:
- Article
Corrigendum: All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation.
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- Scientific Reports, 2016, p. 27678, doi. 10.1038/srep27678
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- Publication type:
- Article
All trans-retinoic acid analogs promote cancer cell apoptosis through non-genomic Crabp1 mediating ERK1/2 phosphorylation.
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- Scientific Reports, 2016, p. 22396, doi. 10.1038/srep22396
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- Publication type:
- Article
Suppressive effects of RXR agonist PA024 on adrenal CYP11B2 expression, aldosterone secretion and blood pressure.
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- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0181055
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- Article
Structural Development of Silicon‐Containing Retinoids: Structure–Activity Relationship Study of the Hydrophobic Pharmacophore of Retinobenzoic Acids Using Silyl Functionalities.
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- ChemMedChem, 2022, v. 17, n. 12, p. 1, doi. 10.1002/cmdc.202200176
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- Article
Structural Development of Salicylanilide‐Based SPAK Inhibitors as Candidate Antihypertensive Agents.
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- ChemMedChem, 2021, v. 16, n. 18, p. 2817, doi. 10.1002/cmdc.202100273
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- Article
Cover Feature: Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine (ChemMedChem 15/2018).
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- ChemMedChem, 2018, v. 13, n. 15, p. 1489, doi. 10.1002/cmdc.201800495
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- Publication type:
- Article
Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.
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- ChemMedChem, 2018, v. 13, n. 15, p. 1530, doi. 10.1002/cmdc.201800233
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- Publication type:
- Article
Two new alkaloids from Crinum asiaticum var. japonicum.
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- Journal of Natural Medicines, 2019, v. 73, n. 3, p. 648, doi. 10.1007/s11418-019-01304-9
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- Publication type:
- Article
Targeting Cellular Retinoic Acid Binding Protein 1 with Retinoic Acid-like Compounds to Mitigate Motor Neuron Degeneration.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4980, doi. 10.3390/ijms24054980
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- Article
Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5584, doi. 10.3390/ijms21155584
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- Article
Chemical Screening of Nuclear Receptor Modulators.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5512, doi. 10.3390/ijms21155512
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- Article