Works by Kaeberlein, Matt

Results: 133

Correction: Why Is Aging Conserved and What Can We Do about it?

Published in:

2015

By:

Pitt, Jason N.;
Kaeberlein, Matt

Publication type:

Correction Notice

Why Is Aging Conserved and What Can We Do about It?

Published in:

PLoS Biology, 2015, v. 13, n. 4, p. 1, doi. 10.1371/journal.pbio.1002131

By:

Pitt, Jason N.;
Kaeberlein, Matt

Publication type:

Article

Sir2-Independent Life Span Extension by Calorie Restriction in Yeast.

Published in:

PLoS Biology, 2004, v. 2, n. 9, p. 1381, doi. 10.1371/journal.pbio.0020296

By:

Kaeberlein, Matt;
Kirkland, Kathryn T.;
Fields, Stanley;
Kennedy, Brian K.

Publication type:

Article

Sir2-Independent Life Span Extension by Calorie Restriction in Yeast.

Published in:

PLoS Biology, 2004, v. 2, n. 8, p. 1, doi. 10.1371/journal.pbio.0020296

By:

Kaeberlein, Matt;
Kirkland, Kathryn T;
Fields, Stanley;
Kennedy, Brian K

Publication type:

Article

Life-Span Extension From Hypoxia in Caenorhabditis elegans Requires Both HIF-1 and DAF-16 and Is Antagonized by SKN-1.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 10, p. 1135, doi. 10.1093/gerona/glt016

By:

Leiser, Scott F.;
Fletcher, Marissa;
Begun, Anisoara;
Kaeberlein, Matt

Publication type:

Article

Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A.

Published in:

2009

By:

Enns LC;
Morton JF;
Mangalindan RS;
McKnight GS;
Schwartz MW;
Kaeberlein MR;
Kennedy BK;
Rabinovitch PS;
Ladiges WC;
Enns, Linda C;
Morton, John F;
Mangalindan, Ruby Sue;
McKnight, G Stanley;
Schwartz, Michael W;
Kaeberlein, Matt R;
Kennedy, Brian K;
Rabinovitch, Peter S;
Ladiges, Warren C

Publication type:

journal article

Attenuation of Age-Related Metabolic Dysfunction in Mice With a Targeted Disruption of the Cβ Subunit of Protein Kinase A.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2009, v. 64A, n. 12, p. 1221, doi. 10.1093/gerona/glp133

By:

Enns, Linda C.;
Morton, John F.;
Mangalindan, Ruby Sue;
McKnight, G. Stanley;
Schwartz, Michael W.;
Kaeberlein, Matt R.;
Kennedy, Brian K.;
Rabinovitch, Peter S.;
Ladiges, Warren C.

Publication type:

Article

The Biological Sciences Section Program at the 60th Annual Meeting of The Gerontological Society of America.

Published in:

2008

By:

Effros, Rita B.;
Austad, Steven;
Blau, Helen;
Chesselet, Marie-Francoise;
Ingram, Donald;
Johnson, Thomas E.;
Kaeberlein, Matt;
Lundblad, Vicki;
McCarter, Roger;
McElhaney, Janet;
Saag, Michael

Publication type:

Proceeding

A Method for High-Throughput Quantitative Analysis of Yeast Chronological Life Span.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2008, v. 63, n. 2, p. 113, doi. 10.1093/gerona/63.2.113

By:

Murakami, Christopher J.;
Burtner, Christopher R.;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

Research to Promote Longevity and Health Span in Companion Dogs: A Pediatric Perspective.

Published in:

American Journal of Bioethics, 2018, v. 18, n. 10, p. 64, doi. 10.1080/15265161.2018.1513591

By:

Wilfond, Benjamin S.;
Porter, Kathryn M.;
Creevy, Kate E.;
Kaeberlein, Matt;
Promislow, Daniel

Publication type:

Article

Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival.

Published in:

Science Translational Medicine, 2012, v. 4, n. 144, p. 1, doi. 10.1126/scitranslmed.3003802

By:

Ramos, Fresnida J.;
Chen, Steven C.;
Garelick, Michael G.;
Dao-Fu Dai;
Chen-Yu Liao;
Schreiber, Katherine H.;
MacKay, Vivian L.;
An, Elroy H.;
Strong, Randy;
Ladiges, Warren C.;
Rabinovitch, Peter S.;
Kaeberlein, Matt;
Kennedy, Brian K.

Publication type:

Article

Age-associated vulval integrity is an important marker of nematode healthspan.

Published in:

Age (0161-9152), 2016, v. 38, n. 5/6, p. 419, doi. 10.1007/s11357-016-9936-8

By:

Leiser, Scott;
Jafari, Gholamali;
Primitivo, Melissa;
Sutphin, George;
Dong, Jingyi;
Leonard, Alison;
Fletcher, Marissa;
Kaeberlein, Matt

Publication type:

Article

PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae.

Published in:

Age (0161-9152), 2015, v. 37, n. 3, p. 1, doi. 10.1007/s11357-015-9788-7

By:

Cui, Hong-Jing;
Liu, Xin-Guang;
McCormick, Mark;
Wasko, Brian M.;
Zhao, Wei;
He, Xin;
Yuan, Yuan;
Fang, Bing-Xiong;
Sun, Xue-Rong;
Kennedy, Brian K.;
Suh, Yousin;
Zhou, Zhong-Jun;
Kaeberlein, Matt;
Feng, Wen-Li

Publication type:

Article

Deciphering the role of natural variation in age-related protein homeostasis.

Published in:

BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-102

By:

Kaeberlein, Matt

Publication type:

Article

Cell biology: A molecular age barrier.

Published in:

Nature, 2008, v. 454, n. 7205, p. 709, doi. 10.1038/454709a

By:

Kaeberlein, Matt

Publication type:

Article

Medicine: Grapes versus gluttony.

Published in:

Nature, 2006, v. 444, n. 7117, p. 280, doi. 10.1038/nature05308

By:

Kaeberlein, Matt;
Rabinovitch, Peter S.

Publication type:

Article

Late-life dietary folate restriction reduces biosynthesis without compromising healthspan in mice.

Published in:

Life Science Alliance, 2024, v. 7, n. 10, p. 1, doi. 10.26508/lsa.202402868

By:

Blank, Heidi M.;
Hammer, Staci E.;
Boatright, Laurel;
Roberts, Courtney;
Heyden, Katarina E.;
Nagarajan, Aravindh;
Mitsuhiro Tsuchiya;
Brun, Marcel;
Johnson, Charles D.;
Stover, Patrick J.;
Sitcheran, Raquel;
Kennedy, Brian K.;
Adams, L. Garry;
Kaeberlein, Matt;
Field, Martha S.;
Threadgill, David W.;
Andrews-Polymenis, Helene L.;
Polymenis, Michael

Publication type:

Article

Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import.

Published in:

PLoS Genetics, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.pgen.1004860

By:

He, Chong;
Tsuchiyama, Scott K.;
Nguyen, Quynh T.;
Plyusnina, Ekaterina N.;
Terrill, Samuel R.;
Sahibzada, Sarah;
Patel, Bhumil;
Faulkner, Alena R.;
Shaposhnikov, Mikhail V.;
Tian, Ruilin;
Tsuchiya, Mitsuhiro;
Kaeberlein, Matt;
Moskalev, Alexey A.;
Kennedy, Brian K.;
Polymenis, Michael

Publication type:

Article

Lifespan Extension Conferred by Endoplasmic Reticulum Secretory Pathway Deficiency Requires Induction of the Unfolded Protein Response.

Published in:

PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004019

By:

Labunskyy, Vyacheslav M.;
Gerashchenko, Maxim V.;
Delaney, Joe R.;
Kaya, Alaattin;
Kennedy, Brian K.;
Kaeberlein, Matt;
Gladyshev, Vadim N.

Publication type:

Article

The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1.

Published in:

PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003708

By:

O'Leary, Monique N.;
Schreiber, Katherine H.;
Zhang, Yong;
Duc, Anne-Cécile E.;
Rao, Shuyun;
Hale, J. Scott;
Academia, Emmeline C.;
Shah, Shreya R.;
Morton, John F.;
Holstein, Carly A.;
Martin, Dan B.;
Kaeberlein, Matt;
Ladiges, Warren C.;
Fink, Pamela J.;
MacKay, Vivian L.;
Wiest, David L.;
Kennedy, Brian K.

Publication type:

Article

A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan.

Published in:

PLoS Genetics, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pgen.1003329

By:

Kwan, Elizabeth X.;
Foss, Eric J.;
Tsuchiyama, Scott;
Alvino, Gina M.;
Kruglyak, Leonid;
Kaeberlein, Matt;
Raghuraman, M. K.;
Brewer, Bonita J.;
Kennedy, Brian K.;
Bedalov, Antonio

Publication type:

Article

Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae.

Published in:

PLoS Genetics, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.pgen.1002253

By:

Kruegel, Undine;
Robison, Brett;
Dange, Thomas;
Kahlert, Günther;
Delaney, Joe R.;
Kotireddy, Soumya;
Tsuchiya, Mitsuhiro;
Tsuchiyama, Scott;
Murakami, Christopher J.;
Schleit, Jennifer;
Sutphin, George;
Carr, Daniel;
Tar, Krisztina;
Dittmar, Gunnar;
Kaeberlein, Matt;
Kennedy, Brian K.;
Schmidt, Marion

Publication type:

Article

Recent Developments in Yeast Aging.

Published in:

PLoS Genetics, 2007, v. 3, n. 5, p. e84, doi. 10.1371/journal.pgen.0030084

By:

Kaeberlein, Matt;
Burtner, Christopher R.;
Kennedy, Brian K.

Publication type:

Article

Author's Reply.

Published in:

2006

By:

Kaeberlein, Matt;
Hu, Di;
Kerr, Emily O.;
Tsuchiya, Mitsuhiro;
Westman, Eric A.;
Dang, Nick;
Fields, Stanley;
Kennedy, Brian K.

Publication type:

Letter

Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast.

Published in:

PLoS Genetics, 2005, v. 1, n. 5, p. 614, doi. 10.1371/journal.pgen.0010069

By:

Kaeberlein, Matt;
Hu, Di;
Kerr, Emily O.;
Tsuchiya, Mitsuhiro;
Westman, Eric A.;
Dang, Nick;
Fields, Stanley;
Kennedy, Brian K.;
Kim, Stuart

Publication type:

Article

The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging.

Published in:

Biological Chemistry, 2010, v. 391, n. 10, p. 1131, doi. 10.1515/BC.2010.123

By:

Leiser, Scott F.;
Kaeberlein, Matt

Publication type:

Article

Evaluation of cognitive function in the Dog Aging Project: associations with baseline canine characteristics.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15837-9

By:

Yarborough, Sarah;
Fitzpatrick, Annette;
Schwartz, Stephen M.;
Dog Aging Project Consortium;
Creevy, Kate E.;
Ruple, Audrey;
Wilkins, Vanessa;
Kaeberlein, Matt;
Promislow, Daniel

Publication type:

Article

Purpose, Partnership, and Possibilities: The Implementation of the Dog Aging Project Biobank.

Published in:

Biomarker Insights, 2022, v. 17, p. 1, doi. 10.1177/11772719221137217

By:

Mouttham, Lara;
Castelhano, Marta G;
Akey, Joshua M;
Benton, Brooke;
Borenstein, Elhanan;
Coleman, Amanda E;
Creevy, Kate E;
Crowder, Kyle;
Dunbar, Matthew D;
Ernst, Holley R;
Fajt, Virginia R;
Fitzpatrick, Annette L;
Garrison, Susan J;
Herndon, Reba S;
Jaramilla, Debra;
Jeffery, Unity;
Jonlin, Erica C;
Kaeberlein, Matt;
Karlsson, Elinor K;
Kerr, Kathleen F

Publication type:

Article

Association Between Diet Type and Owner‐Reported Health Conditions in Dogs in the Dog Aging Project.

Published in:

Journal of Veterinary Internal Medicine, 2025, v. 39, n. 3, p. 1, doi. 10.1111/jvim.70060

By:

Ortiz, Alexandra Varela;
Luo, Ingrid;
O'Brien, Janice;
Murphy, Maryanne;
Rollins, Angela Witzel;
Kaeberlein, Matt;
Ruple, Audrey;
Kerr, Kathleen F.;
Tolbert, M. Katherine

Publication type:

Article

Trajectories of Aging: How Systems Biology in Yeast Can Illuminate Mechanisms of Personalized Aging.

Published in:

Proteomics, 2020, v. 20, n. 5/6, p. 1, doi. 10.1002/pmic.201800420

By:

Crane, Matthew M.;
Chen, Kenneth L.;
Blue, Ben W.;
Kaeberlein, Matt

Publication type:

Article

Molecular basis of ageing.

Published in:

EMBO Reports, 2007, v. 8, n. 10, p. 907, doi. 10.1038/sj.embor.7401066

By:

Kaeberlein, Matt

Publication type:

Article

Case report: Severe asymptomatic hypertriglyceridemia associated with long-term low-dose rapamycin administration in a healthy middle-aged Labrador retriever.

Published in:

Frontiers in Veterinary Science, 2023, p. 1, doi. 10.3389/fvets.2023.1285498

By:

Evans, Jeremy B.;
Chou, Lucy;
Kaeberlein, Matt;
Promislow, Daniel E. L.;
Creevy, Kate E.

Publication type:

Article

Evolution of natural lifespan variation and molecular strategies of extended lifespan in yeast.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64860

By:

Kaya, Alaattin;
Zi Jin Phua, Cheryl;
Lee, Mitchell;
Lu Wang;
Tyshkovskiy, Alexander;
Siming Ma;
Barre, Benjamin;
Weiqiang Liu;
Harrison, Benjamin R.;
Xiaqing Zhao;
Xuming Zhou;
Wasko, Brian M.;
Bammler, Theo K.;
EL Promislow, Daniel;
Kaeberlein, Matt;
Gladyshev, Vadim N.

Publication type:

Article

A prion accelerates proliferation at the expense of lifespan.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.60917

By:

Garcia, David M.;
Campbell, Edgar A.;
Jakobson, Christopher M.;
Tsuchiya, Mitsuhiro;
Shaw, Ethan A.;
DiNardo, Acadia L.;
Kaeberlein, Matt;
Jarosz, Daniel F.

Publication type:

Article

A new era for research into aging.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65286

By:

KAEBERLEIN, MATT;
TYLER, JESSICA K.

Publication type:

Article

Preserving Youth: Does Rapamycin Deliver?

Published in:

Science Translational Medicine, 2013, v. 5, n. 211, p. 1, doi. 10.1126/scitranslmed.3007316

By:

Johnson, Simon C.;
Martin, George M.;
Rabinovitch, Peter S.;
Kaeberlein, Matt

Publication type:

Article

Lifespan extension in Caenorhabditis elegans by complete removal of food.

Published in:

Aging Cell, 2006, v. 5, n. 6, p. 487, doi. 10.1111/j.1474-9726.2006.00238.x

By:

Kaeberlein, Tammi L.;
Smith, Erica D.;
Tsuchiya, Mitsuhiro;
Welton, K. Linnea;
Thomas, James H.;
Fields, Stanley;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

Sirtuin-independent effects of nicotinamide on lifespan extension from calorie restriction in yeast.

Published in:

Aging Cell, 2006, v. 5, n. 6, p. 505, doi. 10.1111/j.1474-9726.2006.00240.x

By:

Tsuchiya, Mitsuhiro;
Dang, Nick;
Kerr, Emily O.;
Di Hu;
Steffen, Kristan K.;
Oakes, Jonathan A.;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

In vivo measurements reveal a single 5′-intron is sufficient to increase protein expression level in Caenorhabditis elegans.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45517-0

By:

Crane, Matthew M.;
Sands, Bryan;
Battaglia, Christian;
Johnson, Brock;
Yun, Soo;
Kaeberlein, Matt;
Brent, Roger;
Mendenhall, Alex

Publication type:

Article

Resveratrol and rapamycin: are they anti-aging drugs?

Published in:

BioEssays, 2010, v. 32, n. 2, p. 96, doi. 10.1002/bies.200900171

By:

Kaeberlein, Matt

Publication type:

Article

The effects of resting time, centrifugation time, and technician training on plasma sample quantity and quality: Implications for the Dog Aging Project.

Published in:

Veterinary Clinical Pathology, 2025, v. 54, n. 1, p. 7, doi. 10.1111/vcp.13413

By:

Holland, Sydney N.;
Tinkle, Amanda K.;
Prescott, Jena N.;
Blattman, Brianna L.;
Creevy, Kate E.;
Fajt, Virginia R.;
Akey, Joshua M.;
Benton, Brooke;
Borenstein, Elhanan;
Castelhano, Marta G.;
Coleman, Amanda E.;
Crowder, Kyle;
Dunbar, Matthew D.;
Fitzpatrick, Annette L.;
Jefrey, Unity;
Jonlin, Erica C.;
Kaeberlein, Matt;
Karlsson, Elinor K.;
Kerr, Kathleen F.;
Levine, Jonathan M.

Publication type:

Article

A new chronological survival assay in mammalian cell culture.

Published in:

Cell Cycle, 2012, v. 11, n. 2, p. 201, doi. 10.4161/cc.11.2.18959

By:

Kaeberlein, Matt;
Kennedy, Brian K.

Publication type:

Article

A genomic analysis of chronological longevity factors in budding yeast.

Published in:

Cell Cycle, 2011, v. 10, n. 9, p. 1385, doi. 10.4161/cc.10.9.15464

By:

Burtner, Christopher R.;
Murakami, Christopher J.;
Olsen, Brady;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast.

Published in:

Cell Cycle, 2011, v. 10, n. 1, p. 156, doi. 10.4161/cc.10.1.14457

By:

Delaney, Joe R.;
Murakami, Christopher J.;
Olsen, Brady;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

The hypoxic response and aging.

Published in:

Cell Cycle, 2009, v. 8, n. 15, p. 2324, doi. 10.4161/cc.8.15.9126

By:

Kaeberlein, Matt;
Kapahi, Pankaj

Publication type:

Article

A molecular mechanism of chronological aging in yeast.

Published in:

Cell Cycle, 2009, v. 8, n. 8, p. 1256, doi. 10.4161/cc.8.8.8287

By:

Burtner, Christopher R.;
Murakami, Christopher J.;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

Yeast as a model to understand the interaction between genotype and the response to calorie restriction

Published in:

FEBS Letters, 2012, v. 586, n. 18, p. 2868, doi. 10.1016/j.febslet.2012.07.038

By:

Schleit, Jennifer;
Wasko, Brian M.;
Kaeberlein, Matt

Publication type:

Article

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.

Published in:

BMC Developmental Biology, 2008, v. 8, p. 1, doi. 10.1186/1471-213X-8-49

By:

Smith, Erica D.;
Kaeberlein, Tammi L.;
Lydum, Brynn T.;
Sager, Jennifer;
Welton, K. Linnea;
Kennedy, Brian K.;
Kaeberlein, Matt

Publication type:

Article

The companion dog as a model for inflammaging: a cross-sectional pilot study.

Published in:

GeroScience, 2024, v. 46, n. 6, p. 5395, doi. 10.1007/s11357-024-01217-w

By:

Schmid, Sarah M.;
Hoffman, Jessica M.;
Prescott, Jena;
Ernst, Holley;
Promislow, Daniel E. L.;
Akey, Joshua M.;
Benton, Brooke;
Borenstein, Elhanan;
Castelhano, Marta G.;
Coleman, Amanda E.;
Creevy, Kate E.;
Crowder, Kyle;
Dunbar, Matthew D.;
Fajt, Virginia R.;
Fitzpatrick, Annette L.;
Jeffery, Unity;
Jonlin, Erica C.;
Kaeberlein, Matt;
Karlsson, Elinor K.;
Kerr, Kathleen F.

Publication type:

Article

Evaluation of off-label rapamycin use on oral health.

Published in:

GeroScience, 2024, v. 46, n. 5, p. 4135, doi. 10.1007/s11357-024-01221-0

By:

Hudson, Johnny;
Kaeberlein, Tammi;
Mahal, Akashdeep;
Wong, Nelson;
Ghorbanifarajzadeh, Mina;
Radella, Frank;
Isman, Anar;
Nyquist, Andy;
Zalzala, Sajad;
Haddad, George;
Kaeberlein, Matt;
An, Jonathan Y.

Publication type:

Article