Works by Johnson, Stuart L.

Results: 47

Eps8 Regulates Hair Bundle Length and Functional Maturation of Mammalian Auditory Hair Cells.

Published in:

PLoS Biology, 2011, v. 9, n. 4, p. 1, doi. 10.1371/journal.pbio.1001048

By:

Zampini, Valeria;
Rüttiger, Lukas;
Johnson, Stuart L.;
Franz, Christoph;
Furness, David N.;
Waldhaus, Jörg;
Hao Xiong;
Hackney, Carole M.;
Holley, Matthew C.;
Offenhauser, Nina;
Di Fiore, Pier Paolo;
Knipper, Marlies;
Masetto, Sergio;
Marcotti, Walter

Publication type:

Article

Grxcr1 regulates hair bundle morphogenesis and is required for normal mechanoelectrical transduction in mouse cochlear hair cells.

Published in:

PLoS ONE, 2022, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0261530

By:

Lorente-Cánovas, Beatriz;
Eckrich, Stephanie;
Lewis, Morag A.;
Johnson, Stuart L.;
Marcotti, Walter;
Steel, Karen P.

Publication type:

Article

The Coupling between Ca2+ Channels and the Exocytotic Ca2+ Sensor at Hair Cell Ribbon Synapses Varies Tonotopically along the Mature Cochlea.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 9, p. 2471, doi. 10.1523/JNEUROSCI.2867-16.2017

By:

Johnson, Stuart L.;
Olt, Jennifer;
Soyoun Cho;
von Gersdorff, Henrique;
Marcotti, Walter

Publication type:

Article

Connexin-Mediated Signaling in Nonsensory Cells Is Crucial for the Development of Sensory Inner Hair Cells in the Mouse Cochlea.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 2, p. 258, doi. 10.1523/JNEUROSCI.2251-16.2017

By:

Johnson, Stuart L.;
Houston, Oliver;
Marcotti, Walter;
Ceriani, Federico;
Crispino, Giulia;
Mammano, Fabio;
Zorzi, Veronica;
Polishchuk, Roman;
Polishchuk, Elena

Publication type:

Article

Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 2, p. 336, doi. 10.1523/JNEUROSCI.2439-15.2016

By:

Corns, Laura F.;
Johnson, Stuart L.;
Kros, Corné J.;
Marcotti, Walter

Publication type:

Article

Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 1, p. 222, doi. 10.1523/JNEUROSCI.1808-15.2016

By:

Carrott, Leanne;
Bowl, Michael R.;
Aguilar, Carlos;
Johnson, Stuart L.;
Chessum, Lauren;
West, Melissa;
Morse, Susan;
Dorning, Joanne;
Smart, Elizabeth;
Hardisty-Hughes, Rachel;
Ball, Greg;
Parker, Andrew;
Barnard, Alun R.;
MacLaren, Robert E.;
Wells, Sara;
Marcotti, Walter;
Brown, Steve D. M.

Publication type:

Article

Tonotopic Variation in the Calcium Dependence of Neurotransmitter Release and Vesicle Pool Replenishment at Mammalian Auditory Ribbon Synapses.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 30, p. 7670, doi. 10.1523/JNEUROSCI.0785-08.2008

By:

Johnson, Stuart L.;
Forge, Andrew;
Knipper, Marlies;
Münkner, Stefan;
Marcotti, Walter

Publication type:

Article

Functional maturation of the exocytotic machinery at gerbil hair cell ribbon synapses.

Published in:

Journal of Physiology, 2009, v. 587, n. 8, p. 1715, doi. 10.1113/jphysiol.2009.168542

By:

Johnson, Stuart L.;
Franz, Christoph;
Knipper, Marlies;
Marcotti, Walter

Publication type:

Article

Biophysical properties of CaV1.3 calcium channels in gerbil inner hair cells.

Published in:

Journal of Physiology, 2008, v. 586, n. 4, p. 1029, doi. 10.1113/jphysiol.2007.145219

By:

Johnson, Stuart L.;
Marcotti, Walter

Publication type:

Article

Genetic deletion of SK2 channels in mouse inner hair cells prevents the developmental linearization in the Ca2+ dependence of exocytosis.

Published in:

Journal of Physiology, 2007, v. 583, n. 2, p. 631, doi. 10.1113/jphysiol.2007.136630

By:

Johnson, Stuart L.;
Adelman, John P.;
Marcotti, Walter

Publication type:

Article

Tmc1 is necessary for normal functional maturation and survival of inner and outer hair cells in the mouse cochlea.

Published in:

Journal of Physiology, 2006, v. 574, n. 3, p. 677, doi. 10.1113/jphysiol.2005.095661

By:

Marcotti, Walter;
Erven, Alexandra;
Johnson, Stuart L.;
Steel, Karen P.;
Kros, Corné J.

Publication type:

Article

Increase in efficiency and reduction in Ca2+ dependence of exocytosis during development of mouse inner hair cells.

Published in:

Journal of Physiology, 2005, v. 563, n. 1, p. 177, doi. 10.1113/jphysiol.2004.074740

By:

Johnson, Stuart L.;
Marcotti, Walter;
Kros, Corné J.

Publication type:

Article

A transiently expressed SK current sutstains and modulates action potential activity in immature mouse inner hair cells.

Published in:

Journal of Physiology, 2004, v. 560, n. 3, p. 691, doi. 10.1113/jphysiol.2004.072868

By:

Marcotti, Walter;
Johnson, Stuart L.;
Kros, Corné J.

Publication type:

Article

Effects of intracellular stores and extracellular Ca2+ on Ca2+-activated K+ currents in mature mouse inner hair cells.

Published in:

Journal of Physiology, 2004, v. 557, n. 2, p. 613, doi. 10.1113/jphysiol.2003.060137

By:

Marcotti, Walter;
Johnson, Stuart L.;
Kros, Corné J.

Publication type:

Article

Sodium and calcium currents shape action potentials in immature mouse inner hair cells.

Published in:

Journal of Physiology, 2003, v. 552, n. 3, p. 743, doi. 10.1113/jphysiol.2003.043612

By:

Marcotti, Walter;
Johnson, Stuart L.;
Rüsch, Alfons;
Kros, Corné J.

Publication type:

Article

Developmental changes in the expression of potassium currents of embryonic, neonatal and mature mouse inner hair cells.

Published in:

Journal of Physiology, 2003, v. 548, n. 2, p. 383, doi. 10.1111/j.1469-7793.2003.00383.x

By:

Marcotti, Walter;
Johnson, Stuart L.;
Holley, Matthew C.;
Kros, Corné J.

Publication type:

Article

The Resting Transducer Current Drives Spontaneous Activity in Prehearing Mammalian Cochlear Inner Hair Cells.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 31, p. 10479, doi. 10.1523/JNEUROSCI.0803-12.2012

By:

Johnson, Stuart L.;
Kennedy, Helen J.;
Holley, Matthew C.;
Fettiplace, Robert;
Marcotti, Walter

Publication type:

Article

Lack of Brain-Derived Neurotrophic Factor Hampers Inner Hair Cell Synapse Physiology, But Protects against Noise-Induced Hearing Loss.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 25, p. 8545, doi. 10.1523/JNEUROSCI.1247-12.2012

By:

Zuccotti, Annalisa;
Kuhn, Stephanie;
Johnson, Stuart L.;
Franz, Christoph;
Singer, Wibke;
Hecker, Dietmar;
Geisler, Hyun-Soon;
Köpschall, Iris;
Rohbock, Karin;
Gutsche, Katja;
Dlugaiczyk, Julia;
Schick, Bernhard;
Marcotti, Walter;
Rüttiger, Lukas;
Schimmang, Thomas;
Knipper, Marlies

Publication type:

Article

A critical period of prehearing spontaneous Ca2+ spiking is required for hair‐bundle maintenance in inner hair cells.

Published in:

EMBO Journal, 2023, v. 42, n. 4, p. 1, doi. 10.15252/embj.2022112118

By:

Carlton, Adam J;
Jeng, Jing‐Yi;
Grandi, Fiorella C;
De Faveri, Francesca;
Ceriani, Federico;
De Tomasi, Lara;
Underhill, Anna;
Johnson, Stuart L;
Legan, Kevin P;
Kros, Corné J;
Richardson, Guy P;
Mustapha, Mirna;
Marcotti, Walter

Publication type:

Article

Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells.

Published in:

EMBO Journal, 2019, v. 38, n. 9, p. N.PAG, doi. 10.15252/embj.201899839

By:

Ceriani, Federico;
Hendry, Aenea;
Jeng, Jing‐Yi;
Johnson, Stuart L;
Stephani, Friederike;
Olt, Jennifer;
Holley, Matthew C;
Mammano, Fabio;
Engel, Jutta;
Kros, Corné J;
Simmons, Dwayne D;
Marcotti, Walter

Publication type:

Article

Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells.

Published in:

Nature Neuroscience, 2011, v. 14, n. 6, p. 711, doi. 10.1038/nn.2803

By:

Johnson, Stuart L.;
Eckrich, Tobias;
Kuhn, Stephanie;
Zampini, Valeria;
Franz, Christoph;
Ranatunga, Kishani M.;
Roberts, Terri P.;
Masetto, Sergio;
Knipper, Marlies;
Kros, Corné J.;
Marcotti, Walter

Publication type:

Article

Synaptotagmin IV determines the linear Ca2+ dependence of vesicle fusion at auditory ribbon synapses.

Published in:

Nature Neuroscience, 2010, v. 13, n. 1, p. 45, doi. 10.1038/nn.2456

By:

Johnson, Stuart L.;
Franz, Christoph;
Kuhn, Stephanie;
Furness, David N.;
Rüttiger, Lukas;
Münkner, Stefan;
Rivolta, Marcelo N.;
Seward, Elizabeth P.;
Herschman, Harvey R.;
Engel, Jutta;
Knipper, Marlies;
Marcotti, Walter

Publication type:

Article

Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 3, p. 191, doi. 10.15252/emmm.201505523

By:

Buniello, Annalisa;
Ingham, Neil J;
Lewis, Morag A;
Huma, Andreea C;
Martinez‐Vega, Raquel;
Varela‐Nieto, Isabel;
Vizcay‐Barrena, Gema;
Fleck, Roland A;
Houston, Oliver;
Bardhan, Tanaya;
Johnson, Stuart L;
White, Jacqueline K;
Yuan, Huijun;
Marcotti, Walter;
Steel, Karen P

Publication type:

Article

Membrane capacitance measurement using patch clamp with integrated self-balancing lock-in amplifier.

Published in:

Pflügers Archiv: European Journal of Physiology, 2002, v. 443, n. 4, p. 653, doi. 10.1007/s00424-001-0763-z

By:

Johnson, Stuart L.;
Thomas, Martin V.;
Kros, Corné J.

Publication type:

Article

MET currents and otoacoustic emissions from mice with a detached tectorial membrane indicate the extracellular matrix regulates Ca2+ near stereocilia.

Published in:

Journal of Physiology, 2021, v. 599, n. 7, p. 2015, doi. 10.1113/JP280905

By:

Jeng, Jing‐Yi;
Harasztosi, Csaba;
Carlton, Adam J.;
Corns, Laura F.;
Marchetta, Philine;
Johnson, Stuart L.;
Goodyear, Richard J.;
Legan, Kevin P.;
Rüttiger, Lukas;
Richardson, Guy P.;
Marcotti, Walter

Publication type:

Article

Biophysical and morphological changes in inner hair cells and their efferent innervation in the ageing mouse cochlea.

Published in:

Journal of Physiology, 2021, v. 599, n. 1, p. 269, doi. 10.1113/JP280256

By:

Jeng, Jing‐Yi;
Carlton, Adam J.;
Johnson, Stuart L.;
Brown, Steve D. M.;
Holley, Matthew C.;
Bowl, Michael R.;
Marcotti, Walter

Publication type:

Article

Pathophysiological changes in inner hair cell ribbon synapses in the ageing mammalian cochlea.

Published in:

Journal of Physiology, 2020, v. 598, n. 19, p. 4339, doi. 10.1113/JP280018

By:

Jeng, Jing‐Yi;
Ceriani, Federico;
Olt, Jennifer;
Brown, Steve D. M.;
Holley, Matthew C.;
Bowl, Michael R.;
Johnson, Stuart L.;
Marcotti, Walter

Publication type:

Article

Age‐related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells.

Published in:

Journal of Physiology, 2020, v. 598, n. 18, p. 3891, doi. 10.1113/JP279795

By:

Jeng, Jing‐Yi;
Johnson, Stuart L.;
Carlton, Adam J;
De Tomasi, Lara;
Goodyear, Richard J.;
De Faveri, Francesca;
Furness, David N.;
Wells, Sara;
Brown, Steve D. M.;
Holley, Matthew C.;
Richardson, Guy P.;
Mustapha, Mirna;
Bowl, Michael R.;
Marcotti, Walter

Publication type:

Article

Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea.

Published in:

Journal of Physiology, 2020, v. 598, n. 1, p. 151, doi. 10.1113/JP279012

By:

Jeng, Jing‐Yi;
Ceriani, Federico;
Hendry, Aenea;
Johnson, Stuart L.;
Yen, Piece;
Simmons, Dwayne D.;
Kros, Corné J.;
Marcotti, Walter

Publication type:

Article

Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea.

Published in:

Journal of Physiology, 2019, v. 597, n. 13, p. 3389, doi. 10.1113/JP277997

By:

Bardhan, Tanaya;
Jeng, Jing‐Yi;
Waldmann, Marco;
Ceriani, Federico;
Johnson, Stuart L.;
Olt, Jennifer;
Rüttiger, Lukas;
Marcotti, Walter;
Holley, Matthew C.

Publication type:

Article

In vivo and in vitro biophysical properties of hair cells from the lateral line and inner ear of developing and adult zebrafish.

Published in:

Journal of Physiology, 2014, v. 592, n. 10, p. 2041, doi. 10.1113/jphysiol.2013.265108

By:

Olt, Jennifer;
Johnson, Stuart L.;
Marcotti, Walter

Publication type:

Article

Burst activity and ultrafast activation kinetics of CaV1.3 Ca2+ channels support presynaptic activity in adult gerbil hair cell ribbon synapses.

Published in:

Journal of Physiology, 2013, v. 591, n. 16, p. 3811, doi. 10.1113/jphysiol.2013.251272

By:

Zampini, Valeria;
Johnson, Stuart L.;
Franz, Christoph;
Knipper, Marlies;
Holley, Matthew C.;
Magistretti, Jacopo;
Masetto, Sergio;
Marcotti, Walter

Publication type:

Article

Elementary properties of CaV1.3 Ca2+ channels expressed in mouse cochlear inner hair cells.

Published in:

Journal of Physiology, 2010, v. 588, n. 1, p. 187, doi. 10.1113/jphysiol.2009.181917

By:

Zampini, Valeria;
Johnson, Stuart L.;
Franz, Christoph;
Lawrence, Neil D.;
Münkner, Stefan;
Engel, Jutta;
Knipper, Marlies;
Magistretti, Jacopo;
Masetto, Sergio;
Marcotti, Walter

Publication type:

Article

Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06307-w

By:

Corns, Laura F.;
Johnson, Stuart L.;
Roberts, Terri;
Ranatunga, Kishani M.;
Hendry, Aenea;
Ceriani, Federico;
Safieddine, Saaid;
Steel, Karen P.;
Forge, Andy;
Petit, Christine;
Furness, David N.;
Kros, Corné J.;
Marcotti, Walter

Publication type:

Article

The upregulation of K+ and HCN channels in developing spiral ganglion neurons is mediated by cochlear inner hair cells.

Published in:

Journal of Physiology, 2024, v. 602, n. 20, p. 5329, doi. 10.1113/JP286134

By:

Conrad, Linus J.;
Grandi, Fiorella C.;
Carlton, Adam J.;
Jeng, Jing‐Yi;
de Tomasi, Lara;
Zarecki, Patryk;
Marcotti, Walter;
Johnson, Stuart L.;
Mustapha, Mirna

Publication type:

Article

Fine Tuning of CaV1.3 Ca2+ Channel Properties in Adult Inner Hair Cells Positioned in the Most Sensitive Region of the Gerbil Cochlea.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113750

By:

Zampini, Valeria;
Johnson, Stuart L.;
Franz, Christoph;
Knipper, Marlies;
Holley, Matthew C.;
Magistretti, Jacopo;
Russo, Giancarlo;
Marcotti, Walter;
Masetto, Sergio

Publication type:

Article

The Actin-Binding Proteins Eps8 and Gelsolin Have Complementary Roles in Regulating the Growth and Stability of Mechanosensory Hair Bundles of Mammalian Cochlear Outer Hair Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087331

By:

Olt, Jennifer;
Mburu, Philomena;
Johnson, Stuart L.;
Parker, Andy;
Kuhn, Stephanie;
Bowl, Mike;
Marcotti, Walter;
Brown, Steve D. M.

Publication type:

Article

Development and Function of the Voltage-Gated Sodium Current in Immature Mammalian Cochlear Inner Hair Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045732

By:

Eckrich, Tobias;
Varakina, Ksenya;
Johnson, Stuart L.;
Franz, Christoph;
Singer, Wibke;
Kuhn, Stephanie;
Knipper, Marlies;
Holley, Matthew C.;
Marcotti, Walter;
Barnes, Steven

Publication type:

Article

Current Response in Ca V 1.3–/– Mouse Vestibular and Cochlear Hair Cells.

Published in:

Frontiers in Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnins.2021.749483

By:

Manca, Marco;
Yen, Piece;
Spaiardi, Paolo;
Russo, Giancarlo;
Giunta, Roberta;
Johnson, Stuart L.;
Marcotti, Walter;
Masetto, Sergio

Publication type:

Article

Human Fetal Auditory Stem Cells Can Be Expanded In Vitro and Differentiate Into Functional Auditory Neurons and Hair Cell-Like Cells.

Published in:

Stem Cells, 2009, v. 27, n. 5, p. 1196, doi. 10.1002/stem.62

By:

Wei Chen;
Johnson, Stuart L.;
Marcotti, Walter;
Andrews, Peter W.;
Moore, Harry D.;
Rivolta, Marcelo N.

Publication type:

Article

Restoration of auditory evoked responses by human ES-cell-derived otic progenitors.

Published in:

Nature, 2012, v. 490, n. 7419, p. 278, doi. 10.1038/nature11415

By:

Chen, Wei;
Jongkamonwiwat, Nopporn;
Abbas, Leila;
Eshtan, Sarah Jacob;
Johnson, Stuart L.;
Kuhn, Stephanie;
Milo, Marta;
Thurlow, Johanna K.;
Andrews, Peter W.;
Marcotti, Walter;
Moore, Harry D.;
Rivolta, Marcelo N.

Publication type:

Article

Exocytosis in mouse vestibular Type II hair cells shows a high‐order Ca2+ dependence that is independent of synaptotagmin‐4.

Published in:

Physiological Reports, 2020, v. 8, n. 14, p. 1, doi. 10.14814/phy2.14509

By:

Spaiardi, Paolo;
Marcotti, Walter;
Masetto, Sergio;
Johnson, Stuart L.

Publication type:

Article

Elementary properties of Ca2+ channels and their influence on multivesicular release and phase-locking at auditory hair cell ribbon synapses.

Published in:

Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00123

By:

Magistretti, Jacopo;
Spaiardi, Paolo;
Johnson, Stuart L.;
Masetto, Sergio

Publication type:

Article

Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 1, p. 37, doi. 10.1093/hmg/ddu417

By:

Taylor, Ruth;
Bullen, Anwen;
Johnson, Stuart L.;
Grimm-Günter, Eva-Maria;
Rivero, Francisco;
Marcotti, Walter;
Forge, Andrew;
Daudet, Nicolas

Publication type:

Article

Myosin VI is required for the proper maturation and function of inner hair cell ribbon synapses.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 23, p. 4615, doi. 10.1093/hmg/ddp429

By:

Roux, Isabelle;
Hosie, Suzanne;
Johnson, Stuart L.;
Bahloul, Amel;
Cayet, Nadège;
Nouaille, Sylvie;
Kros, Corné J.;
Petit, Christine;
Safieddine, Saaid

Publication type:

Article

A reduction in Ptprq associated with specific features of the deafness phenotype of the miR-96 mutant mouse diminuendo.

Published in:

European Journal of Neuroscience, 2014, v. 39, n. 5, p. 744, doi. 10.1111/ejn.12484

By:

Chen, Jing;
Johnson, Stuart L.;
Lewis, Morag A.;
Hilton, Jennifer M.;
Huma, Andreea;
Marcotti, Walter;
Steel, Karen P.

Publication type:

Article

Signal transmission in mature mammalian vestibular hair cells.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 01, doi. 10.3389/fncel.2022.806913

By:

Spaiardi, Paolo;
Marcotti, Walter;
Masetto, Sergio;
Johnson, Stuart L.

Publication type:

Article