Works by Imhof, Axel

Results: 108

The role of RNA in the maintenance of chromatin domains as revealed by antibody-mediated proximity labelling coupled to mass spectrometry.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.95718

By:

Choudhury, Rupam;
Venkatasubramani, Anuroop Venkateswaran;
Jie Hua;
Borsò, Marco;
Franconi, Celeste;
Kinkley, Sarah;
Forné, Ignasi;
Imhof, Axel

Publication type:

Article

dMi-2 and ISWI chromatin remodelling factors have distinct nucleosome binding and mobilization properties.

Published in:

EMBO Journal, 2000, v. 19, n. 16, p. 4332, doi. 10.1093/emboj/19.16.4332

By:

Brehm, Alexander;
Längst, Gernot;
Kehle, Johannes;
Clapier, Cedric R.;
Imhof, Axel;
Eberharter, Anton;
Müller, Jürg;
Becker, Peter B.

Publication type:

Article

p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption.

Published in:

EMBO Journal, 1999, v. 18, n. 20, p. 5634, doi. 10.1093/emboj/18.20.5634

By:

Li, Qiao;
Imhof, Axel;
Collingwood, Trevor N.;
Urnov, Fyodor D.;
Wolffe, Alan P.

Publication type:

Article

Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase.

Published in:

EMBO Journal, 1998, v. 17, n. 2, p. 520, doi. 10.1093/emboj/17.2.520

By:

Wong, Jiemin;
Patterton, Danielle;
Imhof, Axel;
Guschin, Dmitry;
Yun-Bo Shi;
Wolffe, Alan P.

Publication type:

Article

Proteome analysis of mitochondrial outer membrane from Neurospora crassa.

Published in:

Proteomics, 2006, v. 6, n. 1, p. 72, doi. 10.1002/pmic.200402084

By:

Simone Schmitt;
Holger Prokisch;
Tilman Schlunck;
David G. Camp;
Uwe Ahting;
Thomas Waizenegger;
Curt Scharfe;
Thomas Meitinger;
Axel Imhof;
Walter Neupert;
Peter J. Oefner;
Doron Rapaport

Publication type:

Article

DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 20, p. 10302, doi. 10.1093/nar/gks801

By:

Gassen, Alwine;
Brechtefeld, Doris;
Schandry, Niklas;
Arteaga-Salas, J. Manuel;
Israel, Lars;
Imhof, Axel;
Janzen, Christian J.

Publication type:

Article

Developmental regulation of N-terminal H2B methylation in Drosophila melanogaster.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 4, p. 1536, doi. 10.1093/nar/gkr935

By:

Villar-Garea, Ana;
Forne, Ignasi;
Vetter, Irene;
Kremmer, Elisabeth;
Thomae, Andreas;
Imhof, Axel

Publication type:

Article

Establishment of Histone Modifications after Chromatin Assembly.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 15, p. 5032, doi. 10.1093/nar/gkp518

By:

Scharf, Annette N. D.;
Barth, Teresa K.;
Imhof, Axel

Publication type:

Article

The Drosophila G9a gene encodes a multi-catalytic histone methyltransferase required for normal development.

Published in:

Nucleic Acids Research, 2006, v. 34, n. 16, p. 4609, doi. 10.1093/nar/gkl640

By:

Stabell, Marianne;
Eskeland, Ragnhild;
Bjørkmo, Mona;
Larsson, Jan;
Aalen, Reidunn B.;
Imhof, Axel;
Lambertsson, Andrew

Publication type:

Article

Morc3 silences endogenous retroviruses by enabling Daxx-mediated histone H3.3 incorporation.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26288-7

By:

Groh, Sophia;
Milton, Anna Viktoria;
Marinelli, Lisa Katherina;
Sickinger, Cara V.;
Russo, Angela;
Bollig, Heike;
de Almeida, Gustavo Pereira;
Schmidt, Andreas;
Forné, Ignasi;
Imhof, Axel;
Schotta, Gunnar

Publication type:

Article

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.

Published in:

Nature Genetics, 2005, v. 37, n. 4, p. 391, doi. 10.1038/ng1531

By:

Fraga, Mario F;
Ballestar, Esteban;
Villar-Garea, Ana;
Boix-Chornet, Manuel;
Espada, Jesus;
Schotta, Gunnar;
Bonaldi, Tiziana;
Haydon, Claire;
Ropero, Santiago;
Petrie, Kevin;
Iyer, N Gopalakrishna;
Pérez-Rosado, Alberto;
Calvo, Enrique;
Lopez, Juan A;
Cano, Amparo;
Calasanz, Maria J;
Colomer, Dolors;
Ángel Piris, Miguel;
Ahn, Natalie;
Imhof, Axel

Publication type:

Article

H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation.

Published in:

PLoS Genetics, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.pgen.1001354

By:

Guillemette, Benoit;
Drogaris, Paul;
Lin, Hsiu-Hsu Sophia;
Armstrong, Harry;
Hiragami-Hamada, Kyoko;
Imhof, Axel;
Bonneil, Éric;
Thibault, Pierre;
Verreault, Alain;
Festenstein, Richard J.

Publication type:

Article

Interaction of HP1 and Brg1/Brm with the Globular Domain of Histone H3 Is Required for HP1-Mediated Repression.

Published in:

PLoS Genetics, 2009, v. 5, n. 12, p. 1, doi. 10.1371/journal.pgen.1000769

By:

Lavigne, Marc;
Eskeland, Ragnhild;
Azebi, Saliha;
Saint-André, Violaine;
Suk Min Jang;
Batsché, Eric;
Hua-Ying Fan;
Kingston, Robert E.;
Imhof, Axel;
Muchardt, Christian

Publication type:

Article

Modifications of the histone N-terminal domains.

Published in:

Molecular Biotechnology, 2001, v. 17, n. 1, p. 1, doi. 10.1385/MB:17:1:01

By:

Imhof, Axel;
Becker, Peter

Publication type:

Article

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm.

Published in:

Molecular Human Reproduction, 2025, v. 31, n. 1, p. 1, doi. 10.1093/molehr/gaaf003

By:

Kruse, Alexander;
Schneider, Simon;
Merges, Gina Esther;
Fröbius, Andreas Christian;
Forné, Ignasi;
Imhof, Axel;
Schorle, Hubert;
Steger, Klaus

Publication type:

Article

Reduced oxygen concentrations regulate the phenotype and function of human granulosa cells in vitro and cause a diminished steroidogenic but increased inflammatory cellular reaction.

Published in:

Molecular Human Reproduction, 2024, v. 30, n. 1, p. 1, doi. 10.1093/molehr/gaad049

By:

Höfner, Maria;
Eubler, Katja;
Herrmann, Carola;
Berg, Ulrike;
Berg, Dieter;
Welter, Harald;
Imhof, Axel;
Forné, Ignasi;
Mayerhofer, Artur

Publication type:

Article

Evidence of a role for cAMP in mitochondrial regulation in ovarian granulosa cells.

Published in:

Molecular Human Reproduction, 2022, v. 28, n. 10, p. 1, doi. 10.1093/molehr/gaac030

By:

Kaseder, Melanie;
Schmid, Nina;
Eubler, Katja;
Goetz, Katharina;
Müller-Taubenberger, Annette;
Dissen, Gregory A;
Harner, Max;
Wanner, Gerhard;
Imhof, Axel;
Forne, Ignasi;
Mayerhofer, Artur

Publication type:

Article

The Drosophila speciation factor HMR localizes to genomic insulator sites.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171798

By:

Gerland, Thomas Andreas;
Sun, Bo;
Smialowski, Pawel;
Lukacs, Andrea;
Thomae, Andreas Walter;
Imhof, Axel

Publication type:

Article

Exploring the Ion Channel TRPV2 and Testicular Macrophages in Mouse Testis.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4727, doi. 10.3390/ijms22094727

By:

Eubler, Katja;
Rantakari, Pia;
Gerke, Heidi;
Herrmann, Carola;
Missel, Annika;
Schmid, Nina;
Walenta, Lena;
Lahiri, Shibojyoti;
Imhof, Axel;
Strauss, Leena;
Poutanen, Matti;
Mayerhofer, Artur;
Talavera, Karel

Publication type:

Article

Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2345, doi. 10.3390/ijms22052345

By:

Murenu, Elisa;
Kostidis, Sarantos;
Lahiri, Shibojyoti;
Geserich, Anna S.;
Imhof, Axel;
Giera, Martin;
Michalakis, Stylianos;
Wijnholds, Jan

Publication type:

Article

Physical Activity Dynamically Regulates the Hippocampal Proteome along the Dorso-Ventral Axis.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 10, p. 3501, doi. 10.3390/ijms21103501

By:

Frey, Surina;
Schieweck, Rico;
Forné, Ignasi;
Imhof, Axel;
Straub, Tobias;
Popper, Bastian;
Kiebler, Michael A.

Publication type:

Article

Improving SWATH‐MS analysis by deep‐learning.

Published in:

Proteomics, 2023, v. 23, n. 9, p. 1, doi. 10.1002/pmic.202200179

By:

Sun, Bo;
Smialowski, Pawel;
Aftab, Wasim;
Schmidt, Andreas;
Forne, Ignasi;
Straub, Tobias;
Imhof, Axel

Publication type:

Article

Front Cover: New Approaches for Absolute Quantification of Stable‐Isotope‐Labeled Peptide Standards for Targeted Proteomics Based on a UV Active Tag.

Published in:

Proteomics, 2020, v. 20, n. 10, p. 1, doi. 10.1002/pmic.202070081

By:

Schnatbaum, Karsten;
Solis‐Mezarino, Victor;
Pokrovsky, Daniil;
Schäfer, Frederike;
Nagl, Dennis;
Hornberger, Lars;
Zerweck, Johannes;
Knaute, Tobias;
Avramova‐Nehmer, Julia;
Schutkowski, Mike;
Hornung, Veit;
Wenschuh, Holger;
Völker‐Albert, Moritz Carl;
Imhof, Axel;
Reimer, Ulf

Publication type:

Article

New Approaches for Absolute Quantification of Stable‐Isotope‐Labeled Peptide Standards for Targeted Proteomics Based on a UV Active Tag.

Published in:

Proteomics, 2020, v. 20, n. 10, p. 1, doi. 10.1002/pmic.202000007

By:

Schnatbaum, Karsten;
Solis‐Mezarino, Victor;
Pokrovsky, Daniil;
Schäfer, Frederike;
Nagl, Dennis;
Hornberger, Lars;
Zerweck, Johannes;
Knaute, Tobias;
Avramova‐Nehmer, Julia;
Schutkowski, Mike;
Hornung, Veit;
Wenschuh, Holger;
Völker‐Albert, Moritz Carl;
Imhof, Axel;
Reimer, Ulf

Publication type:

Article

In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry.

Published in:

Proteomics, 2016, v. 16, n. 3, p. 437, doi. 10.1002/pmic.201500345

By:

Lahiri, Shibojyoti;
Sun, Na;
Solis‐Mezarino, Victor;
Fedisch, Andreas;
Ninkovic, Jovica;
Feuchtinger, Annette;
Götz, Magdalena;
Walch, Axel;
Imhof, Axel

Publication type:

Article

A Focus on Chromatin Proteomics.

Published in:

2016

By:

Imhof, Axel;
Rappsilber, Juri

Publication type:

Editorial

Inside front cover: In situ detection of histone variants and modifications in mouse brain using imaging mass spectrometry.

Published in:

2016

By:

Lahiri, Shibojyoti;
Sun, Na;
Solis‐Mezarino, Victor;
Fedisch, Andreas;
Ninkovic, Jovica;
Feuchtinger, Annette;
Götz, Magdalena;
Walch, Axel;
Imhof, Axel

Publication type:

Other

Identification of novel Drosophila centromere-associated proteins.

Published in:

Proteomics, 2014, v. 14, n. 19, p. 2167, doi. 10.1002/pmic.201400052

By:

Barth, Teresa K.;
Schade, Georg O. M.;
Schmidt, Andreas;
Vetter, Irene;
Wirth, Marc;
Heun, Patrick;
Thomae, Andreas W.;
Imhof, Axel

Publication type:

Article

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin.

Published in:

EMBO Reports, 2009, v. 10, n. 7, p. 769, doi. 10.1038/embor.2009.90

By:

Loyola, Alejandra;
Tagami, Hideaki;
Bonaldi, Tiziana;
Roche, Danièle;
Quivy, Jean Pierre;
Imhof, Axel;
Nakatani, Yoshihiro;
Dent, Sharon Y R;
Almouzni, Geneviève

Publication type:

Article

Physical and functional association of SU(VAR)3-9 and HDAC1 in Drosophila.

Published in:

2001

By:

Czermin, Birgit;
Schotta, Gunnar;
Hülsmann, Bastian B.;
Brehm, Alexander;
Becker, Peter B.;
Reuter, Gunter;
Imhof, Axel

Publication type:

Report

Dietary intervention improves health metrics and life expectancy of the genetically obese Titan mouse.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03339-3

By:

Müller-Eigner, Annika;
Sanz-Moreno, Adrián;
de-Diego, Irene;
Venkatasubramani, Anuroop Venkateswaran;
Langhammer, Martina;
Gerlini, Raffaele;
Rathkolb, Birgit;
Aguilar-Pimentel, Antonio;
Klein-Rodewald, Tanja;
Calzada-Wack, Julia;
Becker, Lore;
Palma-Vera, Sergio;
Gille, Benedikt;
Forne, Ignasi;
Imhof, Axel;
Meng, Chen;
Ludwig, Christina;
Koch, Franziska;
Heiker, John T.;
Kuhla, Angela

Publication type:

Article

SPRTN patient variants cause global-genome DNA-protein crosslink repair defects.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-35988-1

By:

Weickert, Pedro;
Li, Hao-Yi;
Götz, Maximilian J.;
Dürauer, Sophie;
Yaneva, Denitsa;
Zhao, Shubo;
Cordes, Jacqueline;
Acampora, Aleida C.;
Forne, Ignasi;
Imhof, Axel;
Stingele, Julian

Publication type:

Article

A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33108-z

By:

Bachmaier, Sabine;
Giacomelli, Giacomo;
Calvo-Alvarez, Estefanía;
Vieira, Larissa Rezende;
Van Den Abbeele, Jan;
Aristodemou, Aris;
Lorentzen, Esben;
Gould, Matt K.;
Brennand, Ana;
Dupuy, Jean-William;
Forné, Ignasi;
Imhof, Axel;
Bramkamp, Marc;
Salmon, Didier;
Rotureau, Brice;
Boshart, Michael

Publication type:

Article

Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II.

Published in:

Transcription (2154-1264), 2015, v. 6, n. 5, p. 91, doi. 10.1080/21541264.2015.1114983

By:

Voss, Kirsten;
Forné, Ignasi;
Descostes, Nicolas;
Hintermair, Corinna;
Schüller, Roland;
Maqbool, Muhammad Ahmad;
Heidemann, Martin;
Flatley, Andrew;
Imhof, Axel;
Gut, Marta;
Gut, Ivo;
Kremmer, Elisabeth;
Andrau, Jean-Christophe;
Eick, Dirk

Publication type:

Article

Helicobacter hepaticus is required for immune targeting of bacterial heat shock protein 60 and fatal colitis in mice.

Published in:

Gut Microbes, 2021, v. 13, n. 1, p. 1, doi. 10.1080/19490976.2021.1882928

By:

Friedrich, Verena;
Forné, Ignasi;
Matzek, Dana;
Ring, Diana;
Popper, Bastian;
Jochum, Lara;
Spriewald, Stefanie;
Straub, Tobias;
Imhof, Axel;
Krug, Anne;
Stecher, Bärbel;
Brocker, Thomas

Publication type:

Article

Trnp1 organizes diverse nuclear membrane‐less compartments in neural stem cells.

Published in:

EMBO Journal, 2020, v. 39, n. 16, p. 1, doi. 10.15252/embj.2019103373

By:

Esgleas, Miriam;
Falk, Sven;
Forné, Ignasi;
Thiry, Marc;
Najas, Sonia;
Zhang, Sirui;
Mas‐Sanchez, Aina;
Geerlof, Arie;
Niessing, Dierk;
Wang, Zefeng;
Imhof, Axel;
Götz, Magdalena

Publication type:

Article

Altered Localization of Hybrid Incompatibility Proteins in Drosophila.

Published in:

Molecular Biology & Evolution, 2019, v. 36, n. 8, p. 1783, doi. 10.1093/molbev/msz105

By:

Cooper, Jacob Carter;
Lukacs, Andrea;
Reich, Shelley;
Schauer, Tamas;
Imhof, Axel;
Phadnis, Nitin

Publication type:

Article

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-023-44538-8

By:

Kohler, Verena;
Kohler, Andreas;
Berglund, Lisa Larsson;
Hao, Xinxin;
Gersing, Sarah;
Imhof, Axel;
Nyström, Thomas;
Höög, Johanna L.;
Ott, Martin;
Andréasson, Claes;
Büttner, Sabrina

Publication type:

Article

Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity.

Published in:

EMBO Molecular Medicine, 2022, v. 14, n. 10, p. 1, doi. 10.15252/emmm.202216084

By:

Güner, Gökhan;
Aßfalg, Marlene;
Zhao, Kai;
Dreyer, Tobias;
Lahiri, Shibojyoti;
Lo, Yun;
Slivinschi, Bianca Ionela;
Imhof, Axel;
Jocher, Georg;
Strohm, Laura;
Behrends, Christian;
Langosch, Dieter;
Bronger, Holger;
Nimsky, Christopher;
Bartsch, Jörg W;
Riddell, Stanley R;
Steiner, Harald;
Lichtenthaler, Stefan F

Publication type:

Article

Every methyl counts – Epigenetic calculus

Published in:

FEBS Letters, 2011, v. 585, n. 13, p. 2001, doi. 10.1016/j.febslet.2010.11.029

By:

Scharf, Annette N.D.;
Imhof, Axel

Publication type:

Article

Bioinformatic analysis of proteomics data.

Published in:

BMC Systems Biology, 2014, v. 8, n. Suppl 2, p. 1, doi. 10.1186/1752-0509-8-S2-S3

By:

Schmidt, Andreas;
Forne, Ignasi;
Imhof, Axel

Publication type:

Article

MALDI imaging mass spectrometry as a novel tool for detecting histone modifications in clinical tissue samples.

Published in:

Expert Review of Proteomics, 2016, v. 13, n. 3, p. 275, doi. 10.1586/14789450.2016.1146598

By:

Lahiri, Shibojyoti;
Sun, Na;
Buck, Achim;
Imhof, Axel;
Walch, Axel

Publication type:

Article

Monomethylation of Lysine 20 on Histone H4 Facilitates Chromatin Maturation.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 1, p. 57, doi. 10.1128/MCB.00989-08

By:

Scharf, Annette N. D.;
Meier, Karin;
Seitz, Volker;
Kremmer, Elisabeth;
Brehm, Alexander;
Imhof, Axel

Publication type:

Article

HP1 Binding to Chromatin Methylated at H3K9 Is Enhanced by Auxiliary Factors.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 2, p. 4, doi. 10.1128/MCB.01576-06

By:

Eskeland, Ragnhild;
Eberharter, Anton;
Imhof, Axel

Publication type:

Article

A systemic cell cycle block impacts stage-specific histone modification profiles during Xenopus embryogenesis.

Published in:

PLoS Biology, 2021, v. 19, n. 9, p. 1, doi. 10.1371/journal.pbio.3001377

By:

Pokrovsky, Daniil;
Forné, Ignasi;
Straub, Tobias;
Imhof, Axel;
Rupp, Ralph A. W.

Publication type:

Article

Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells.

Published in:

Journal of Cell Biology, 2015, v. 211, n. 3, p. 553, doi. 10.1083/jcb.201503128

By:

Schulz, Anna M.;
Stutte, Susanne;
Hogl, Sebastian;
Luckashenak, Nancy;
Dudziak, Diana;
Leroy, Céline;
Forné, Ignasi;
Imhof, Axel;
Müller, Stephan A.;
Brakebusch, Cord H.;
Lichtenthaler, Stefan F.;
Brocker, Thomas

Publication type:

Article

Characterization of the insertase for β-barrel proteins of the outer mitochondrial membrane.

Published in:

Journal of Cell Biology, 2012, v. 199, n. 4, p. 599, doi. 10.1083/jcb.201207161

By:

Klein, Astrid;
Israel, Lars;
Lackey, Sebastian W. K.;
Nargang, Frank E.;
Imhof, Axel;
Baumeister, Wolfgang;
Neupert, Walter;
Thomas, Dennis R.

Publication type:

Article

Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly.

Published in:

Journal of Cell Biology, 2011, v. 193, n. 6, p. 1101, doi. 10.1083/jcb.201103132

By:

Gruschke, Steffi;
Kehrein, Kirsten;
Römpler, Katharina;
Gröne, Kerstin;
Israel, Lars;
Imhof, Axel;
Herrmann, Johannes M.;
Ott, Martin

Publication type:

Article

Impairment of prostate cancer cell growth by a selective and reversible lysine-specific demethylase 1 inhibitor.

Published in:

International Journal of Cancer, 2012, v. 131, n. 11, p. 2704, doi. 10.1002/ijc.27555

By:

Willmann, Dominica;
Lim, Soyoung;
Wetzel, Stefan;
Metzger, Eric;
Jandausch, Anett;
Wilk, Wolfram;
Jung, Manfred;
Forne, Ignasi;
Imhof, Axel;
Janzer, Andreas;
Kirfel, Jutta;
Waldmann, Herbert;
Schüle, Roland;
Buettner, Reinhard

Publication type:

Article

The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila.

Published in:

PLoS Genetics, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.pgen.1009744

By:

Lukacs, Andrea;
Thomae, Andreas W.;
Krueger, Peter;
Schauer, Tamas;
Venkatasubramani, Anuroop V.;
Kochanova, Natalia Y.;
Aftab, Wasim;
Choudhury, Rupam;
Forne, Ignasi;
Imhof, Axel

Publication type:

Article