Works by Hobo, Willemijn

Results: 23

Good manufacturing practice production of an off-the-shelf CD34+ progenitor-derived NK cell product with preserved anti-tumor functionality post-infusion in NOD/SCID/IL2Rgnull mice.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05727-4

By:

Hooijmaijers, Laura;
Vidal-Manrique, Marcos;
Spils, Bart;
van Ens, Diede;
Rodriguez, Verónica Castaño;
Hobo, Willemijn;
de Goede, Anna L.;
van Dorp, Suzanne;
Jansen, Joop H.;
van der Waart, Anniek B.;
de Jonge, Paul K. J. D.;
Dolstra, Harry

Publication type:

Article

P475: EMERGING LEUKEMIA ASSOCIATED IMMUNOPHENOTYPES (LAIPS) IN BONE MARROW OF ACUTE MYELOID LEUKEMIA PATIENTS AFTER INTENSIVE CHEMOTHERAPY.

Published in:

HemaSphere, 2023, v. 7, p. 1, doi. 10.1097/01.HS9.0000968808.37084.f7

By:

Lam Ngai, Lok;
Hanekamp, Diana;
Kelder, Angèle;
Scholten, Willemijn J.;
Carbaat ‐ Ham, Jannemieke;
Snel, Alexander N.;
Bachas, Costa;
Tettero, Jesse;
van der Velden, Vincent;
Slomp, Jennichjen;
Hobo, Willemijn;
Breems, Dimitri;
Fischer, Thomas;
Tore Gjertsen, Bjorn;
Griškevičius, Laimonas;
Juliusson, Gunnar;
Maertens, Johan;
Manz, Markus;
Pabst, Thomas;
Passweg, Jakob

Publication type:

Article

Immunotherapeutic approaches to treat multiple myeloma.

Published in:

Human Vaccines & Immunotherapeutics, 2014, v. 10, n. 4, p. 1, doi. 10.4161/hv.27380

By:

Roeven, Mieke W. H.;
Hobo, Willemijn;
Schaap, Nicolaas;
Dolstra, Harry

Publication type:

Article

CD34+ progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rgnull mice.

Published in:

OncoImmunology, 2021, v. 10, n. 1, p. 1, doi. 10.1080/2162402X.2021.1981049

By:

Van der Meer, Jolien M. R.;
de Jonge, Paul K. J. D.;
van der Waart, Anniek B.;
Geerlings, Alexander C.;
Moonen, Jurgen P.;
Brummelman, Jolanda;
de Klein, Janne;
Vermeulen, Malou C.;
Maas, Ralph J. A.;
Schaap, Nicolaas P. M.;
Hoogstad-van Evert, Janneke S.;
Ottevanger, Petronella B.;
Jansen, Joop H.;
Hobo, Willemijn;
Dolstra, Harry

Publication type:

Article

TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer.

Published in:

OncoImmunology, 2020, v. 9, n. 1, p. 1, doi. 10.1080/2162402X.2020.1843247

By:

Maas, Ralph Ja;
Hoogstad-van Evert, Janneke S;
Van der Meer, Jolien Mr;
Mekers, Vera;
Rezaeifard, Somayeh;
Korman, Alan J;
de Jonge, Paul Kjd;
Cany, Jeannette;
Woestenenk, Rob;
Schaap, Nicolaas Pm;
Massuger, Leon F;
Jansen, Joop H;
Hobo, Willemijn;
Dolstra, Harry

Publication type:

Article

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy.

Published in:

OncoImmunology, 2018, v. 7, n. 10, p. 1, doi. 10.1080/2162402X.2018.1488565

By:

Mousset, Charlotte M.;
Hobo, Willemijn;
Fredrix, Hanny;
Jansen, Joop H.;
Dolstra, Harry;
van der Waart, Anniek B.;
Ji, Yun;
Gattinoni, Luca;
De Giorgi, Valeria;
Allison, Robert D.;
Kester, Michel G. D.;
Falkenburg, J. H. Frederik;
Schaap, Nicolaas P. M.

Publication type:

Article

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo.

Published in:

OncoImmunology, 2017, v. 6, n. 3, p. N.PAG, doi. 10.1080/2162402X.2017.1285991

By:

Thordardottir, Soley;
Schaap, Nicolaas;
Louer, Elja;
Kester, Michel G. D.;
Falkenburg, J. H. Frederik;
Jansen, Joop;
Radstake, Timothy R. D.;
Hobo, Willemijn;
Dolstra, Harry

Publication type:

Article

Time to Akt.

Published in:

OncoImmunology, 2015, v. 4, n. 5, p. 0, doi. 10.1080/2162402X.2014.1003016

By:

van der Waart, Anniek B;
Hobo, Willemijn;
Dolstra, Harry

Publication type:

Article

Reprogramming of myeloid cells and their progenitors in patients with non-medullary thyroid carcinoma.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33907-4

By:

Rabold, Katrin;
Zoodsma, Martijn;
Grondman, Inge;
Kuijpers, Yunus;
Bremmers, Manita;
Jaeger, Martin;
Zhang, Bowen;
Hobo, Willemijn;
Bonenkamp, Han J.;
de Wilt, Johannes H. W.;
Janssen, Marcel J. R.;
Cornelissen, Lenneke A. M.;
van Engen-van Grunsven, Ilse C. H.;
Mulder, Willem J. M.;
Smit, Jan W. A.;
Adema, Gosse J.;
Netea, Mihai G.;
Li, Yang;
Xu, Cheng-Jian;
Netea-Maier, Romana T.

Publication type:

Article

Flow cytometric analysis of myelodysplasia: Pre‐analytical and technical issues—Recommendations from the European LeukemiaNet.

Published in:

Cytometry. Part B, 2023, v. 104, n. 1, p. 15, doi. 10.1002/cyto.b.22046

By:

van der Velden, Vincent H. J.;
Preijers, Frank;
Johansson, Ulrika;
Westers, Theresia M.;
Dunlop, Alan;
Porwit, Anna;
Béné, Marie C.;
Valent, Peter;
te Marvelde, Jeroen;
Wagner‐Ballon, Orianne;
Oelschlaegel, Uta;
Saft, Leonie;
Kordasti, Sharham;
Ireland, Robin;
Cremers, Eline;
Alhan, Canan;
Duetz, Carolien;
Hobo, Willemijn;
Chapuis, Nicolas;
Fontenay, Michaela

Publication type:

Article

Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS‐Flow Cytometry Working Group.

Published in:

Cytometry. Part B, 2023, v. 104, n. 1, p. 77, doi. 10.1002/cyto.b.22044

By:

van de Loosdrecht, Arjan A.;
Kern, Wolfgang;
Porwit, Anna;
Valent, Peter;
Kordasti, Sharham;
Cremers, Eline;
Alhan, Canan;
Duetz, Carolien;
Dunlop, Alan;
Hobo, Willemijn;
Preijers, Frank;
Wagner‐Ballon, Orianne;
Chapuis, Nicolas;
Fontenay, Michaela;
Bettelheim, Peter;
Eidenschink‐Brodersen, Lisa;
Font, Patricia;
Johansson, Ulrika;
Loken, Michael R.;
te Marvelde, Jeroen G.

Publication type:

Article

OMIP ‐ 081: A new 21‐monoclonal antibody 10‐color panel for diagnostic polychromatic immunophenotyping.

Published in:

Cytometry. Part A, 2022, v. 101, n. 2, p. 117, doi. 10.1002/cyto.a.24511

By:

Huys, Erik H. L. P. G.;
Hobo, Willemijn;
Preijers, Frank W. M. B.

Publication type:

Article

Comprehensive Phenotyping of T Cells Using Flow Cytometry.

Published in:

Cytometry. Part A, 2019, v. 95, n. 6, p. 647, doi. 10.1002/cyto.a.23724

By:

Mousset, Charlotte M.;
Hobo, Willemijn;
Woestenenk, Rob;
Preijers, Frank;
Dolstra, Harry;
van der Waart, Anniek B.

Publication type:

Article

Clinically applicable CD34+-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses.

Published in:

Cancer Immunology, Immunotherapy, 2021, v. 70, n. 11, p. 3167, doi. 10.1007/s00262-021-02899-3

By:

van Eck van der Sluijs, Jesper;
van Ens, Diede;
Thordardottir, Soley;
Vodegel, Denise;
Hermens, Inge;
van der Waart, Anniek B.;
Falkenburg, J. H. Frederik;
Kester, Michel G. D.;
de Rink, Iris;
Heemskerk, Mirjam H. M.;
Borst, Jannie;
Schaap, Nicolaas P. M.;
Jansen, Joop H.;
Xiao, Yanling;
Dolstra, Harry;
Hobo, Willemijn

Publication type:

Article

Cell composition and expansion strategy can reduce the beneficial effect of AKT-inhibition on functionality of CD8+ T cells.

Published in:

Cancer Immunology, Immunotherapy, 2020, v. 69, n. 11, p. 2259, doi. 10.1007/s00262-020-02612-w

By:

Mousset, Charlotte M.;
Hobo, Willemijn;
de Ligt, Aafke;
Baardman, Sjoerd;
Schaap, Nicolaas P. M.;
Jansen, Joop H.;
van der Waart, Anniek B.;
Dolstra, Harry

Publication type:

Article

siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8 T cells in NOD/SCID/IL2Rg(null) mice.

Published in:

Cancer Immunology, Immunotherapy, 2015, v. 64, n. 5, p. 645, doi. 10.1007/s00262-015-1668-6

By:

van der Waart, Anniek;
Fredrix, Hanny;
van der Voort, Robbert;
Schaap, Nicolaas;
Hobo, Willemijn;
Dolstra, Harry

Publication type:

Article

Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 8, p. 1381, doi. 10.1007/s00262-013-1438-2

By:

Hobo, Willemijn;
Strobbe, Leonie;
Maas, Frans;
Fredrix, Hanny;
Greupink-Draaisma, Annelies;
Esendam, Ben;
Witte, Theo;
Preijers, Frank;
Levenga, Henriëtte;
Rees, Bas;
Raymakers, Reinier;
Schaap, Nicolaas;
Dolstra, Harry

Publication type:

Article

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation.

Published in:

Cancer Immunology, Immunotherapy, 2013, v. 62, n. 2, p. 285, doi. 10.1007/s00262-012-1334-1

By:

Hobo, Willemijn;
Novobrantseva, Tatiana;
Fredrix, Hanny;
Wong, Jamie;
Milstein, Stuart;
Epstein-Barash, Hila;
Liu, Ju;
Schaap, Nicolaas;
Voort, Robbert;
Dolstra, Harry

Publication type:

Article

Increased peritoneal TGF-b1 is associated with ascites-induced NK-cell dysfunction and reduced survival in high-grade epithelial ovarian cancer.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1448041

By:

Maas, Ralph J. A.;
Hoogstad-van Evert, Janneke S.;
Hagemans, Iris M.;
Brummelman, Jolanda;
van Ens, Diede;
de Jonge, Paul K. J. D.;
Hooijmaijers, Laura;
Mahajan, Shweta;
van der Waart, Anniek B.;
Hermans, Charlotte K. J. C.;
de Klein, Janne;
Woestenenk, Rob;
van Herwaarden, Antonius E.;
Schaap, Nicolaas P. M.;
Rezaeifard, Somayeh;
Tauriello, Daniele V. F.;
Zusterzeel, Petra L. M.;
Ottevanger, Nelleke;
Jansen, Joop H.;
Hobo, Willemijn

Publication type:

Article

Immune checkpoint molecules in acute myeloid leukaemia: managing the double‐edged sword.

Published in:

British Journal of Haematology, 2018, v. 181, n. 1, p. 38, doi. 10.1111/bjh.15078

By:

Hobo, Willemijn;
Hutten, Tim J. A.;
Schaap, Nicolaas P. M.;
Dolstra, Harry

Publication type:

Article

Analytical assay validation for acute myeloid leukemia measurable residual disease assessment by multiparametric flow cytometry.

Published in:

Cytometry. Part B, 2023, v. 104, n. 6, p. 426, doi. 10.1002/cyto.b.22144

By:

Tettero, Jesse M.;
Dakappagari, Naveen;
Heidinga, Maaike E.;
Oussoren‐Brockhoff, Yvonne;
Hanekamp, Diana;
Pahuja, Anil;
Burns, Kerri;
Kaur, Pavinder;
Alfonso, Zeni;
van der Velden, Vincent H. J.;
te Marvelde, Jeroen G.;
Hobo, Willemijn;
Slomp, Jennichjen;
Bachas, Costa;
Kelder, Angele;
Nguyen, Kevin;
Cloos, Jacqueline

Publication type:

Article

Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by In Situ Silencing of Programmed-Death Ligands.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.734256

By:

Versteven, Maarten;
Flumens, Donovan;
Campillo-Davó, Diana;
De Reu, Hans;
Van Bruggen, Laura;
Peeters, Stefanie;
Van Tendeloo, Viggo;
Berneman, Zwi;
Dolstra, Harry;
Anguille, Sébastien;
Hobo, Willemijn;
Smits, Evelien;
Lion, Eva

Publication type:

Article

Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo.

Published in:

Cellular & Molecular Life Sciences, 2023, v. 80, n. 10, p. 1, doi. 10.1007/s00018-023-04923-4

By:

van Eck van der Sluijs, Jesper;
van Ens, Diede;
Brummelman, Jolanda;
Heister, Daan;
Sareen, Aastha;
Truijen, Lisa;
van Ingen Schenau, Dorette S.;
Heemskerk, Mirjam H. M.;
Griffioen, Marieke;
Kester, Michel G. D.;
Schaap, Nicolaas P. M.;
Jansen, Joop H.;
van der Waart, Anniek B.;
Dolstra, Harry;
Hobo, Willemijn

Publication type:

Article

Works by Hobo, Willemijn

Good manufacturing practice production of an off-the-shelf CD34<sup>+</sup> progenitor-derived NK cell product with preserved anti-tumor functionality post-infusion in NOD/SCID/IL2Rg<sup>null</sup> mice.

P475: EMERGING LEUKEMIA ASSOCIATED IMMUNOPHENOTYPES (LAIPS) IN BONE MARROW OF ACUTE MYELOID LEUKEMIA PATIENTS AFTER INTENSIVE CHEMOTHERAPY.

Immunotherapeutic approaches to treat multiple myeloma.

CD34<sup>+</sup> progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rg<sup>null</sup> mice.

TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer.

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8<sup>+</sup> T cells for adoptive immunotherapy.

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo.

Time to Akt.

Reprogramming of myeloid cells and their progenitors in patients with non-medullary thyroid carcinoma.

Flow cytometric analysis of myelodysplasia: Pre‐analytical and technical issues—Recommendations from the European LeukemiaNet.

Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS‐Flow Cytometry Working Group.

OMIP ‐ 081: A new 21‐monoclonal antibody 10‐color panel for diagnostic polychromatic immunophenotyping.

Comprehensive Phenotyping of T Cells Using Flow Cytometry.

Clinically applicable CD34<sup>+</sup>-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses.

Cell composition and expansion strategy can reduce the beneficial effect of AKT-inhibition on functionality of CD8<sup>+</sup> T cells.

siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8 T cells in NOD/SCID/IL2Rg(null) mice.

Immunogenicity of dendritic cells pulsed with MAGE3, Survivin and B-cell maturation antigen mRNA for vaccination of multiple myeloma patients.

Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation.

Increased peritoneal TGF-b1 is associated with ascites-induced NK-cell dysfunction and reduced survival in high-grade epithelial ovarian cancer.

Immune checkpoint molecules in acute myeloid leukaemia: managing the double‐edged sword.

Analytical assay validation for acute myeloid leukemia measurable residual disease assessment by multiparametric flow cytometry.

Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by In Situ Silencing of Programmed-Death Ligands.

Human CD34<sup>+</sup>-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8<sup>+</sup> T cell and NK cell responses in vitro and in vivo.