Works by Gust, Ronald

Results: 81

Development of heterodimeric estrogen receptor alpha antagonists to target simultaneously the ligand and coactivator binding site.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 7, p. 1, doi. 10.1002/ardp.202200638

By:

Hörmann, Nikolas;
Kalchschmid, Christina;
Grabher, Patricia;
Grassmayr, Isabella;
Kapitza, Paul;
Kaserer, Teresa;
Gust, Ronald

Publication type:

Article

Synthesis and biological evaluation of salophen nickel(II) and cobalt(III) complexes as potential anticancer compounds.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 5, p. 1, doi. 10.1002/ardp.202200655

By:

Ma, Benjamin N.;
Baecker, Daniel;
Descher, Hubert;
Brandstaetter, Philipp;
Hermann, Martin;
Kircher, Brigitte;
Gust, Ronald

Publication type:

Article

Structure–activity relationship study to improve cytotoxicity and selectivity of lonafarnib against breast cancer cells.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 4, p. 1, doi. 10.1002/ardp.202200263

By:

Hongnak, Siriwat;
Gust, Ronald

Publication type:

Article

Development of methylated cobalt–alkyne complexes with selective cytotoxicity against COX‐positive cancer cell lines.

Published in:

Archiv der Pharmazie, 2022, v. 355, n. 2, p. 1, doi. 10.1002/ardp.202100408

By:

Baecker, Daniel;
Sagasser, Jessica;
Karaman, Serhat;
Hörmann, Anton Amadeus;
Gust, Ronald

Publication type:

Article

Specific labeling with potent radiolabels alters the uptake of cell-penetrating peptides.

Published in:

Biopolymers, 2009, v. 92, n. 5, p. 445, doi. 10.1002/bip.21218

By:

Walther, Cornelia;
Ott, Ingo;
Gust, Ronald;
Neundorf, Ines

Publication type:

Article

Probing the Paradigm of Promiscuity for N‐Heterocyclic Carbene Complexes and their Protein Adduct Formation.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 36, p. 19928, doi. 10.1002/anie.202106906

By:

Sullivan, Matthew P.;
Cziferszky, Monika;
Tolbatov, Iogann;
Truong, Dianna;
Mercadante, Davide;
Re, Nazzareno;
Gust, Ronald;
Goldstone, David C.;
Hartinger, Christian G.

Publication type:

Article

Aβ42-lowering compounds interfere with APP transmembrane sequence dimerization

Published in:

2010

By:

Richter, Luise;
Munter, Lisa-Marie;
Ness, Julia;
Hildebrand, Peter W.;
Joshi, Mangesh;
Unterreitmeier, Stephanie;
Bulic, Bruno;
Beyermann, Michael;
Gust, Ronald;
Reif, Bernd;
Weggen, Sascha;
Langosch, Dieter;
Multhaup, Gerd

Publication type:

Abstract

Cell death‐inducing properties of selected dendrimers against different breast cancer and leukemia cell lines.

Published in:

Archiv der Pharmazie, 2020, v. 353, n. 11, p. 1, doi. 10.1002/ardp.202000209

By:

Baecker, Daniel;
Kapp, Timo;
Schumacher, Petra;
Gust, Ronald;
Kircher, Brigitte

Publication type:

Article

Synthesis, Antitumor, and Antibacterial Activity of Bis[4,5-diarylimidazol-2-ylidene]methane Derivatives.

Published in:

Archiv der Pharmazie, 2012, v. 345, n. 7, p. 557, doi. 10.1002/ardp.201100474

By:

Liu, Wukun;
Chen, Xiaohua;
Gust, Ronald

Publication type:

Article

Synthesis, Characterisation and Biological Evaluation of Copper and Silver Complexes based on Acetylsalicylic Acid.

Published in:

Archiv der Pharmazie, 2011, v. 344, n. 10, p. 684, doi. 10.1002/ardp.201000382

By:

Rubner, Gerhard;
Bensdorf, Kerstin;
Wellner, Anja;
Bergemann, Silke;
Gust, Ronald

Publication type:

Article

Licofelone-Nitric Oxide Donors as Anticancer Agents.

Published in:

Archiv der Pharmazie, 2011, v. 344, n. 8, p. 487, doi. 10.1002/ardp.201000397

By:

Liu, Wukun;
Zhou, Jinpei;
Liu, Yinglin;
Liu, Haoran;
Bensdorf, Kerstin;
Guo, Cancheng;
Gust, Ronald

Publication type:

Article

Synthesis and Biological Activities of 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives.

Published in:

Archiv der Pharmazie, 2011, v. 344, n. 7, p. 451, doi. 10.1002/ardp.201000281

By:

Liu, Wukun;
Zhou, Jinpei;
Qi, Fan;
Bensdorf, Kerstin;
Li, Zhiyu;
Zhang, Huibin;
Qian, Hai;
Huang, Wenlong;
Cai, Xueting;
Cao, Peng;
Wellner, Anja;
Gust, Ronald

Publication type:

Article

Effects of Metal Salophene and Saldach Complexes on Lymphoma and Leukemia Cells.

Published in:

Archiv der Pharmazie, 2011, v. 344, n. 4, p. 217, doi. 10.1002/ardp.201000237

By:

Hille, Annegret;
Wolf, Tanja;
Schumacher, Petra;
Ott, Ingo;
Gust, Ronald;
Kircher, Brigitte

Publication type:

Article

Enantiomerically Pure [1, 2-Diamino-1-(4-fluorophenyl)butane]platinum(II) Complexes: Synthesis and Antitumor Activity against MCF-7 and MDA-MB 231 Breast Cancer and LnCaP/FGC Prostate Cancer Cell Lines.

Published in:

Archiv der Pharmazie, 2004, v. 337, n. 12, p. 654, doi. 10.1002/ardp.200400621

By:

Anja Dullin;
Francois Dufrasne;
Michael Gelbcke;
Ronald Gust

Publication type:

Article

Invesgations on the Influence of Halide Substituents on the Estrogen Receptor Interaction of 2, 4, 5-Tris(4-hydroxyphenyl)imidazoles.

Published in:

Archiv der Pharmazie, 2003, v. 336, n. 10, p. 456, doi. 10.1002/ardp.200300729

By:

Ronald Gust;
Sandra Busch;
Roland Keilitz;
Kathrin Schmidt;
Moriz von Rauch

Publication type:

Article

Non-thiol Farnesyltransferase Inhibitors: FTase-Inhibition and Cellular Activity of Benzophenone-based Bisubstrate Analogue Farnesyltransferase Inhibitors.

Published in:

Archiv der Pharmazie, 2003, v. 336, n. 4/5, p. 242, doi. 10.1002/ardp.200300758

By:

Andreas Mitsch;
Silke Bergemann;
Ronald Gust;
Isabel Sattler;
Martin Schlitzer

Publication type:

Article

Synthesis, Structural Evaluation, and Estrogen Receptor Interaction of 4, 5-Bis(4-hydroxyphenyl)imidazoles.

Published in:

Archiv der Pharmazie, 2002, v. 335, n. 10, p. 463, doi. 10.1002/ardp.200290000

By:

Gust, Ronald;
Keilitz, Roland;
Schmidt, Kathrin;
von Rauch, Moriz

Publication type:

Article

Synthesis and Antitumor Activity of Enantiomerically Pure [1, 2-Diamino-1-(4-fluorophenyl) propane]dichloroplatinum(II) Complexes.

Published in:

Archiv der Pharmazie, 2002, v. 335, n. 5, p. 229, doi. 10.1002/1521-4184(200205)335:5<229::AID-ARDP229>3.0.CO;2-Q

By:

Dufrasne, Francois;
Gelbcke, Michael;
Schnurr, Beate;
Gust, Ronald

Publication type:

Article

1-(2,6-Dichloro-4-hydroxyphenyl)-2-phenylethanes - New Biological Response Modifiers for the Therapy of Breast Cancer. Synthesis and Evaluation of Estrogenic/Antiestrogenic Properties.

Published in:

Archiv der Pharmazie, 2001, v. 334, n. 4, p. 125, doi. 10.1002/1521-4184(200104)334:4<125::AID-ARDP125>3.0.CO;2-D

By:

Schertl, Sabine;
Hartmann, Rolf W.;
Batzl-Hartmann, Christine;
Schlemmer, Richard;
Spruß, Thilo;
Bernhardt, Günther;
Gust, Ronald;
Schönenberger, Helmut

Publication type:

Article

Synthesis, Conformational Studies, and Investigations on the Estrogen Receptor Binding of [ R/S-1-(2,6-Dichloro-4-hydroxyphenyl)-ethylenediamine]platinum(II) Complexes.

Published in:

Archiv der Pharmazie, 2001, v. 334, n. 3, p. 93, doi. 10.1002/1521-4184(200103)334:3<93::AID-ARDP93>3.0.CO;2-2

By:

Gust, Ronald;
Lubczyk, Veronika;
Schmidt, Kathrin;
Shihada, Undine

Publication type:

Article

Inhibitors of Histone Deacetylase Suppress the Growth of MCF-7 Breast Cancer Cells.

Published in:

Archiv der Pharmazie, 1999, v. 332, n. 10, p. 353, doi. 10.1002/(SICI)1521-4184(199910)332:10<353::AID-ARDP353>3.0.CO;2-X

By:

Schmidt, Kathrin;
Gust, Ronald;
Jung, Manfred

Publication type:

Article

Structure Activity Studies on Leaving Group Derivatives of [meso-1,2-Bis-(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]-platinum(II).

Published in:

Archiv der Pharmazie, 1999, v. 332, n. 8, p. 261, doi. 10.1002/(SICI)1521-4184(19998)332:8<261::AID-ARDP261>3.0.CO;2-0

By:

Gust, Ronald;
Keilitz, Roland;
Krauser, Rudolf;
Schmidt, Kathrin;
Schnurr, Beate

Publication type:

Article

[meso-1,2-Bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamine]sulfato-platinum(II) - Pharmacokinetic Studies.

Published in:

Archiv der Pharmazie, 1999, v. 332, n. 6, p. 195, doi. 10.1002/(SICI)1521-4184(19996)332:6<195::AID-ARDP195>3.0.CO;2-H

By:

Bernhardt, Günther;
Koch, Marion;
Spruß, Thilo;
Gust, Ronald;
Krauser, Rudolf;
Schlemmer, Richard;
Hollstein, Michael;
Lux, Franz;
Schönenberger, Helmut

Publication type:

Article

Synthesis and Antitumor Activity of [1,2-Bis(4-fluorophenyl)ethylenediamine][dicarboxylato]platinum(II) Complexes.

Published in:

Archiv der Pharmazie, 1998, v. 331, n. 1, p. 27, doi. 10.1002/(SICI)1521-4184(199801)331:1<27::AID-ARDP27>3.0.CO;2-X

By:

Gust, Ronald;
Krauser, Rudolf;
Schmid, Beate;
Schönenberger, Helmut

Publication type:

Article

Development of a Parenterally Administrable Hydrosol Preparation of the 'Third Generation Platinum Complex' [(±)-1,2-Bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and Studies on the Stability and Antitumor Activity.

Published in:

Archiv der Pharmazie, 1995, v. 328, n. 9, p. 645, doi. 10.1002/ardp.19953280904

By:

Gust, Ronald;
Bernhardt, Gunther;
Spruß, Thilo;
Krauser, Rudolf;
Koch, Marion;
Schönenberger, Helmut;
Bauer, Kurt-Heinz;
Schertl, Sabine;
Lu, Zhi

Publication type:

Article

Third Generation Antitumor Platinum(II) Complexes of the [1-(Fluoro/difluorophenyl)-2-phenylethylenediamine]platinum(II) Type.

Published in:

Archiv der Pharmazie, 1995, v. 328, n. 7/8, p. 595, doi. 10.1002/ardp.19953280706

By:

Gust, Ronald;
Schönenberger, Helmut

Publication type:

Article

Reduction of the Estrogenic Side Effects of the Mammary Tumor-Inhibiting Drug [1,2-Bis(2,6-dichloro-4-hydroxyphenyl)-ethylenediamine]dichloroplatinum(II) by Variation of Ring Substituents.

Published in:

Archiv der Pharmazie, 1995, v. 328, n. 5, p. 457, doi. 10.1002/ardp.19953280511

By:

Gust, Ronald;
Karl, Johann;
Faderl, Michael;
Schönenberger, Helmut

Publication type:

Article

Investigation of the Conformational Influences on the Estrogenic Activity of 1,2-Bis(2,6-dichloro-4-hydroxyphenyl)-ethylenediamines and of their Platinum(II) Complexes, II: Synthesis and Studies on the Estrogenic Activity of cis- and trans[Bis(2,6-dichloro-4-hydroxybenzylamine)]dihaloplatinum(II)-Complexes

Published in:

Archiv der Pharmazie, 1994, v. 327, n. 12, p. 763, doi. 10.1002/ardp.19943271203

By:

Gust, Ronald;
Schönenberger, Helmut

Publication type:

Article

Aqua[1,1-bis(4-hydroxyphenyl)-1,2-diamino-2-phenylethane]-sulfatoplatinum(II), a New Compound for the Treatment of the Mammary Carcinoma.

Published in:

Archiv der Pharmazie, 1994, v. 327, n. 1, p. 49, doi. 10.1002/ardp.19943270109

By:

Gust, Ronald

Publication type:

Article

Aqua[1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethylenediamine]sulfatoplatinum(II) Complexes with Variable Substituents in the 2-Phenyl Ring, II: Correlation of Molecular Structure and Estrogenic Activity of Breast and Prostate Cancer Inhibiting [ erythro-1-(2,6-Dichloro-4-hydroxyphenyl)-2-(2-halo-4-hydroxyphenyl)ethylenediamine]platinum(II) Complexes

Published in:

Archiv der Pharmazie, 1993, v. 326, n. 12, p. 967, doi. 10.1002/ardp.19933261211

By:

Gust, Ronald;
Schönenberger, Helmut;
Klement, Ulrich;
Range, Klaus-Jürgen

Publication type:

Article

Mammary Tumor Inhibiting [1,2-Bis(2,6-dihalo-3-hydroxyphenyl)ethylenediamine]platinum(II) Complexes, III: Relationship between Structure and Estrogenic Activity of the Diamine Ligands, their Sulfatoplatinum (II) and Diiodoplatinum(II) Complexes.

Published in:

Archiv der Pharmazie, 1993, v. 326, n. 7, p. 405, doi. 10.1002/ardp.19933260707

By:

Gust, Ronald;
Schönenberger, Helmut

Publication type:

Article

Evaluation of the Mammary Tumor Inhibiting Properties.

Published in:

Archiv der Pharmazie, 1992, v. 325, n. 2, p. 113, doi. 10.1002/ardp.19923250211

By:

Schertl, Sabine;
Gust, Ronald;
Müller, Richard;
Spruß, Thilo;
Schönenberger, Helmut

Publication type:

Article

Dichloro-[1-(hydroxyphenyl)-2-phenylethylenediamine]platinum(II) Complexes: Testing on the Human Ovarian Cancer Cell Lines NIH: OVCAR 3 and SK OV 3.

Published in:

Archiv der Pharmazie, 1992, v. 325, n. 2, p. 93, doi. 10.1002/ardp.19923250208

By:

Bernhardt, Günther;
Müller, Richard;
Gust, Ronald;
Reile, Herta;
Keller, Christoph;
Spruß, Thilo;
Schönenberger, Helmut

Publication type:

Article

Tumor Inhibiting [1,2-Bis(fluorophenyl)ethylenediamine]platinum(II) Complexes. Part IV: Biological Evaluation - in vivo Studies on the P 388 Leukemia.

Published in:

Archiv der Pharmazie, 1991, v. 324, n. 7, p. 405, doi. 10.1002/ardp.19913240702

By:

Reile, Herta;
Spruß, Thilo;
Bernhardt, Günther;
Müller, Richard;
Gust, Ronald;
Schönenberger, Helmut

Publication type:

Article

Initial In Vitro and In Vivo Evaluation of a Novel CCK2R Targeting Peptide Analog Labeled with Lutetium-177.

Published in:

Molecules, 2020, v. 25, n. 19, p. 4585, doi. 10.3390/molecules25194585

By:

Hörmann, Anton Amadeus;
Klingler, Maximilian;
Rezaeianpour, Maliheh;
Hörmann, Nikolas;
Gust, Ronald;
Shahhosseini, Soraya;
Guggenberg, Elisabeth von;
Kumar, Krishan

Publication type:

Article

Conformational Analysis of Bivalent Estrogen Receptor Ligands: From Intramolecular to Intermolecular Binding.

Published in:

ChemBioChem, 2011, v. 12, n. 17, p. 2587, doi. 10.1002/cbic.201100529

By:

Shan, Min;
Bujotzek, Alexander;
Abendroth, Frank;
Wellner, Anja;
Gust, Ronald;
Seitz, Oliver;
Weber, Marcus;
Haag, Rainer

Publication type:

Article

Benzimidazole-Based NHC Metal Complexes as Anticancer Drug Candidates: Gold(I) vs. Platinum(II).

Published in:

Inorganics, 2023, v. 11, n. 7, p. 293, doi. 10.3390/inorganics11070293

By:

Kapitza, Paul;
Grabher, Patricia;
Scherfler, Amelie;
Wurst, Klaus;
Kircher, Brigitte;
Gust, Ronald;
Varbanov, Hristo P.

Publication type:

Article

Synthesis and Characterization of Telmisartan‐Derived Cell Death Modulators to Circumvent Imatinib Resistance in Chronic Myeloid Leukemia.

Published in:

ChemMedChem, 2020, v. 15, n. 12, p. 1067, doi. 10.1002/cmdc.202000092

By:

Schoepf, Anna M.;
Salcher, Stefan;
Hohn, Verena;
Veider, Florina;
Obexer, Petra;
Gust, Ronald

Publication type:

Article

The Biological Activity of Zeise's Salt and its Derivatives.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 9, p. 2834, doi. 10.1002/anie.201410357

By:

Meieranz, Sandra;
Stefanopoulou, Maria;
Rubner, Gerhard;
Bensdorf, Kerstin;
Kubutat, Dominic;
Sheldrick, William S.;
Gust, Ronald

Publication type:

Article

A highly sensitive method for in vitro testing of fluorinated drug candidates using high-resolution continuum source molecular absorption spectrometry (HR-CS MAS).

Published in:

Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 14, p. 3431, doi. 10.1007/s00216-014-7780-1

By:

Würtenberger, Irene;
Gust, Ronald

Publication type:

Article

Development and validation of a LC method for the separation and determination of the anticancer-active Fe<sup>III</sup>(4-methoxy-salophene) using the new second-generation monolith.

Published in:

Journal of Separation Science, 2012, v. 35, n. 24, p. 3434, doi. 10.1002/jssc.201200734

By:

El Deeb, Sami;
Ma, Benjamin N.;
Gust, Ronald

Publication type:

Article

Design, synthesis, and biological evaluation of novel halogenated chlorido[N,N′-bis(salicylidene)-1,2-bis(3-methoxyphenyl)ethylenediamine]iron(III) complexes as anticancer agents.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2024, v. 29, n. 6, p. 583, doi. 10.1007/s00775-024-02067-9

By:

Bernkop-Schnürch, Astrid Dagmar;
Huber, Klaus;
Clauser, Armida;
Cziferszky, Monika;
Leitner, Daniel;
Talasz, Heribert;
Hermann, Martin;
Hohloch, Stephan;
Gust, Ronald;
Kircher, Brigitte

Publication type:

Article

Top-down mass spectrometry reveals multiple interactions of an acetylsalicylic acid bearing Zeise's salt derivative with peptides.

Published in:

Journal of Biological Inorganic Chemistry (JBIC), 2020, v. 25, n. 2, p. 285, doi. 10.1007/s00775-020-01760-9

By:

Cziferszky, Monika;
Gust, Ronald

Publication type:

Article

Microindoline 581, an Indole Derivative from Microbacterium Sp. RP581 as A Novel Selective Antineoplastic Agent to Combat Hepatic Cancer Cells: Production, Optimization and Structural Elucidation.

Published in:

Iranian Journal of Pharmaceutical Research, 2020, v. 19, n. 4, p. 290, doi. 10.22037/ijpr.2020.111982.13469

By:

Pournejati, Roya;
Gust, Ronald;
Kircher, Brigitte;
Karbalaei-Heidari, Hamid Reza

Publication type:

Article

Synthesis, Characterization, and in vitro Antiproliferative Activity of [Salophene]platinum(II) Complexes.

Published in:

ChemMedChem, 2014, v. 9, n. 6, p. 1176, doi. 10.1002/cmdc.201402123

By:

Proetto, Maria T.;
Liu, Wukun;
Molchanov, Andrey;
Sheldrick, William S.;
Hagenbach, Adelheid;
Abram, Ulrich;
Gust, Ronald

Publication type:

Article

Characterization of Telmisartan-Derived PPARγ Agonists: Importance of Moiety Shift from Position 6 to 5 on Potency, Efficacy and Cofactor Recruitment.

Published in:

ChemMedChem, 2012, v. 7, n. 11, p. 1935, doi. 10.1002/cmdc.201200337

By:

Herbst, Lena;
Goebel, Matthias;
Bandholtz, Sebastian;
Gust, Ronald;
Kintscher, Ulrich

Publication type:

Article

Development of 2,3,5-Triaryl-1 H-pyrroles as Estrogen Receptor α Selective Ligands.

Published in:

ChemMedChem, 2011, v. 6, n. 11, p. 2055, doi. 10.1002/cmdc.201100283

By:

Schäfer, Anja;
Wellner, Anja;
Strauss, Martin;
Wolber, Gerhard;
Gust, Ronald

Publication type:

Article

Synthesis and Investigations on the Oxidative Degradation of C3/C5-Alkyl-1,2,4-triarylpyrroles as Ligands for the Estrogen Receptor.

Published in:

ChemMedChem, 2011, v. 6, n. 5, p. 794, doi. 10.1002/cmdc.201000537

By:

Schäfer, Anja;
Wellner, Anja;
Gust, Ronald

Publication type:

Article

Cellular Selectivity and Biological Impact of Cytotoxic Rhodium(III) and Iridium(III) Complexes Containing Methyl-Substituted Phenanthroline Ligands.

Published in:

ChemMedChem, 2011, v. 6, n. 3, p. 429, doi. 10.1002/cmdc.201000517

By:

Geldmacher, Yvonne;
Kitanovic, Igor;
Alborzinia, Hamed;
Bergerhoff, Katharina;
Rubbiani, Riccardo;
Wefelmeier, Pascal;
Prokop, Aram;
Gust, Ronald;
Ott, Ingo;
Wölfl, Stefan;
Sheldrick, William S.

Publication type:

Article

Characterization of New PPARγ Agonists: Benzimidazole Derivatives - the Importance of Position 2.

Published in:

ChemMedChem, 2009, v. 4, n. 7, p. 1136, doi. 10.1002/cmdc.200900067

By:

Goebel, Matthias;
Staels, Bart;
Unger, Thomas;
Kintscher, Ulrich;
Gust, Ronald

Publication type:

Article