Works by Fairlie, David P.
Results: 121
Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity.
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- FASEB Journal, 2002, v. 16, n. 11, p. 1458, doi. 10.1096/fj.02-0181fje
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- Article
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.
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- Angewandte Chemie, 2024, v. 136, n. 31, p. 1, doi. 10.1002/ange.202400632
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- Article
Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides.
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- Angewandte Chemie, 2022, v. 134, n. 29, p. 1, doi. 10.1002/ange.202203995
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- Article
Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability.
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- Angewandte Chemie, 2021, v. 133, n. 15, p. 8466, doi. 10.1002/ange.202012643
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- Article
Mechanische Verstärkung von Coiled Coils mit Lactam und Histidin‐Metall‐Klammern.
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- Angewandte Chemie, 2021, v. 133, n. 1, p. 234, doi. 10.1002/ange.202006971
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- Article
A Novel Long‐Range n to π* Interaction Secures the Smallest known α‐Helix in Water.
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- Angewandte Chemie, 2019, v. 131, n. 52, p. 19049, doi. 10.1002/ange.201911277
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- Article
Protease activated receptor 2 controls myelin development, resiliency and repair.
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- Glia, 2017, v. 65, n. 12, p. 2070, doi. 10.1002/glia.23215
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Protease‐activated receptor 2 does not contribute to renal inflammation or fibrosis in the obstructed kidney.
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- Nephrology, 2019, v. 24, n. 9, p. 983, doi. 10.1111/nep.13635
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A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.
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- Biosensors (2079-6374), 2012, v. 2, n. 3, p. 273, doi. 10.3390/bios2030273
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- Article
Conformational homogeneity in molecular recognition by proteolytic enzymes.
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- Journal of Molecular Recognition, 1999, v. 12, n. 6, p. 363, doi. 10.1002/(SICI)1099-1352(199911/12)12:6<363::AID-JMR478>3.0.CO;2-M
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PAR2 Activation on Human Kidney Tubular Epithelial Cells Induces Tissue Factor Synthesis, That Enhances Blood Clotting.
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- Frontiers in Physiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphys.2021.615428
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Characterization of Copper Interactions with Alzheimer Amyloid β Peptides.
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- Journal of Neurochemistry, 2000, v. 75, n. 3, p. 1219, doi. 10.1046/j.1471-4159.2000.0751219.x
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Varicella Zoster Virus disrupts MAIT cell polyfunctional effector responses.
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- PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012372
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- Article
Front Cover: Late‐Stage Hydrocarbon Conjugation and Cyclisation in Synthetic Peptides and Proteins (ChemBioChem 10/2021).
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- ChemBioChem, 2021, v. 22, n. 10, p. 1686, doi. 10.1002/cbic.202100189
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- Article
Late‐Stage Hydrocarbon Conjugation and Cyclisation in Synthetic Peptides and Proteins.
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- ChemBioChem, 2021, v. 22, n. 10, p. 1784, doi. 10.1002/cbic.202000796
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Histone deacetylase 7 activates 6-phosphogluconate dehydrogenase via an enzyme-independent mechanism that involves the N-terminal protein-protein interaction domain.
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- Biochemical Journal, 2024, v. 481, n. 21, p. 1569, doi. 10.1042/BCJ20240380
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A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.
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- Journal of Cell Biology, 2022, v. 221, n. 12, p. 1, doi. 10.1083/jcb.202110125
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Hepta and octapeptide agonists of protease-activated receptor 2.
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- Journal of Peptide Science, 2007, v. 13, n. 12, p. 856, doi. 10.1002/psc.912
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Catalyst-Free N-Arylation Using Unactivated Fluorobenzenes.
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- Angewandte Chemie International Edition, 2012, v. 51, n. 32, p. 8012, doi. 10.1002/anie.201202149
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Protein α-Turns Recreated in Structurally Stable Small Molecules.
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- Angewandte Chemie International Edition, 2011, v. 50, n. 47, p. 11107, doi. 10.1002/anie.201105119
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Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides.
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- ChemBioChem, 2015, v. 16, n. 16, p. 2289, doi. 10.1002/cbic.201500441
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D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A<sub>2</sub> (IIa) with Antiinflammatory Activity.
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- ChemBioChem, 2003, v. 4, n. 2/3, p. 181, doi. 10.1002/cbic.200390029
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T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
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- Nature, 2014, v. 509, n. 7500, p. 361, doi. 10.1038/nature13160
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- Article
MR1 presents microbial vitamin B metabolites to MAIT cells.
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- Nature, 2012, v. 491, n. 7426, p. 717, doi. 10.1038/nature11605
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Histone deacetylase inhibitors as suppressors of bone destruction in inflammatory diseases.
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- Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 6, p. 763, doi. 10.1111/j.2042-7158.2011.01421.x
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PAR2 activation on human tubular epithelial cells engages converging signaling pathways to induce an inflammatory and fibrotic milieu.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1382094
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High Cell Permeability Does Not Predict Oral Bioavailability for Analogues of Cyclic Heptapeptide Sanguinamide A*.
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- Australian Journal of Chemistry, 2020, v. 73, n. 4, p. 344, doi. 10.1071/CH19479
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Alpha Helix Nucleation by a Simple Cyclic Tetrapeptide.
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- Australian Journal of Chemistry, 2017, v. 70, n. 2, p. 213, doi. 10.1071/CH16591
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A small molecule C5a receptor antagonist protects kidneys from ischemia/reperfusion injury in rats.
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- Kidney International, 2003, v. 63, n. 1, p. 134, doi. 10.1046/j.1523-1755.2003.00737.x
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- Article
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis.
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- Angewandte Chemie International Edition, 2024, v. 63, n. 31, p. 1, doi. 10.1002/anie.202400632
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- Article
MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection.
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- Science Immunology, 2024, v. 9, n. 102, p. 1, doi. 10.1126/sciimmunol.adp9841
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Sulfated bile acid is a host-derived ligand for MAIT cells.
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- Science Immunology, 2024, v. 9, n. 91, p. 1, doi. 10.1126/sciimmunol.ade6924
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The balance of interleukin‐12 and interleukin‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection.
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- Immunology & Cell Biology, 2022, v. 100, n. 7, p. 547, doi. 10.1111/imcb.12556
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Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophages.
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- Immunology & Cell Biology, 2020, v. 98, n. 7, p. 528, doi. 10.1111/imcb.12363
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An overview on the identification of MAIT cell antigens.
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- Immunology & Cell Biology, 2018, v. 96, n. 6, p. 573, doi. 10.1111/imcb.12057
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Human blood MAIT cell subsets defined using MR1 tetramers.
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- Immunology & Cell Biology, 2018, v. 96, n. 5, p. 507, doi. 10.1111/imcb.12021
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C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.
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- Immunology & Cell Biology, 2013, v. 91, n. 10, p. 625, doi. 10.1038/icb.2013.48
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Lysine acetylation in obesity, diabetes and metabolic disease.
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- Immunology & Cell Biology, 2012, v. 90, n. 1, p. 39, doi. 10.1038/icb.2011.99
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HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation.
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- Immunology & Cell Biology, 2012, v. 90, n. 1, p. 14, doi. 10.1038/icb.2011.88
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HDACs and their inhibitors in immunology: teaching anticancer drugs new tricks.
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- Immunology & Cell Biology, 2012, v. 90, n. 1, p. 3, doi. 10.1038/icb.2011.105
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A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis.
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- British Journal of Pharmacology, 2024, v. 181, n. 23, p. 4804, doi. 10.1111/bph.17306
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Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00414-w
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Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells.
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- Nature Communications, 2017, v. 8, n. 3, p. 14599, doi. 10.1038/ncomms14599
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Downsizing a human inflammatory protein to a small molecule with equal potency and functionality.
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- Nature Communications, 2013, v. 4, n. 11, p. 2802, doi. 10.1038/ncomms3802
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Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
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- Nature Communications, 2013, v. 4, n. 7, p. 2142, doi. 10.1038/ncomms3142
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Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA.
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- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133805
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Differential location of NKT and MAIT cells within lymphoid tissue.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07704-4
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Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis.
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- Rheumatology, 2015, v. 54, n. 9, p. 1713, doi. 10.1093/rheumatology/kev022
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MAIT cells protect against pulmonary Legionella longbeachae infection.
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- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05202-8
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Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines.
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- PLoS ONE, 2021, v. 16, n. 3, p. 1, doi. 10.1371/journal.pone.0248983
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