Works by Chabes, Andrei
Results: 42
A geographically matched control population efficiently limits the number of candidate disease-causing variants in an unbiased whole-genome analysis.
- Published in:
- PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0213350
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- Publication type:
- Article
DNA Building Blocks at the Foundation of Better Survival.
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- Cell Cycle, 2003, v. 2, n. 3, p. 172, doi. 10.4161/cc.2.3.354
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- Publication type:
- Article
The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage.
- Published in:
- EMBO Journal, 2001, v. 20, n. 13, p. 3544, doi. 10.1093/emboj/20.13.3544
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- Article
Replication-IDentifier links epigenetic and metabolic pathways to the replication stress response.
- Published in:
- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56561-y
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- Publication type:
- Article
Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51821-9
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- Publication type:
- Article
Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae.
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- G3: Genes | Genomes | Genetics, 2018, v. 8, n. 8, p. 2551, doi. 10.1534/g3.118.200280
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- Article
Ribonucleotides in mitochondrial DNA.
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- FEBS Letters, 2019, v. 593, n. 13, p. 1554, doi. 10.1002/1873-3468.13440
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- Article
dNTP pools determine fork progression and origin usage under replication stress.
- Published in:
- EMBO Journal, 2012, v. 31, n. 4, p. 883, doi. 10.1038/emboj.2011.470
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- Article
Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype.
- Published in:
- EMBO Journal, 2012, v. 31, n. 4, p. 895, doi. 10.1038/emboj.2011.485
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- Publication type:
- Article
Chl1 helicase controls replication fork progression by regulating dNTP pools.
- Published in:
- Life Science Alliance, 2022, v. 5, n. 4, p. 1, doi. 10.26508/lsa.202101153
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- Publication type:
- Article
Phosphines are ribonucleotide reductase reductants that act via C-terminal cysteines similar to thioredoxins and glutaredoxins.
- Published in:
- Scientific Reports, 2014, p. 1, doi. 10.1038/srep05539
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- Publication type:
- Article
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08145-2
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- Publication type:
- Article
Increased and Imbalanced dNTP Pools Symmetrically Promote Both Leading and Lagging Strand Replication Infidelity.
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- PLoS Genetics, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.pgen.1004846
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- Publication type:
- Article
H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly.
- Published in:
- PLoS Genetics, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.pgen.1004667
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- Publication type:
- Article
Ixr1 Is Required for the Expression of the Ribonucleotide Reductase Rnr1 and Maintenance of dNTP Pools.
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- PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002061
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- Publication type:
- Article
Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools.
- Published in:
- Genetics, 2013, v. 193, n. 4, p. 1095, doi. 10.1534/genetics.112.149120
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- Article
Corrigendum: Phosphines are ribonucleotide reductase reductants that act via C-terminal cysteines similar to thioredoxins and glutaredoxins.
- Published in:
- Scientific Reports, 2017, p. 45880, doi. 10.1038/srep45880
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- Article
NME6: ribonucleotide salvage sustains mitochondrial transcription.
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- 2023
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- Publication type:
- Editorial
Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage.
- Published in:
- EMBO Journal, 2018, v. 37, n. 21, p. N.PAG, doi. 10.15252/embj.201899319
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- Publication type:
- Article
Rtt105 functions as a chaperone for replication protein A to preserve genome stability.
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- EMBO Journal, 2018, v. 37, n. 17, p. 1, doi. 10.15252/embj.201899154
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- Publication type:
- Article
Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites.
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- PLoS Genetics, 2018, v. 14, n. 1, p. 1, doi. 10.1371/journal.pgen.1007129
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- Publication type:
- Article
Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres.
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- PLoS Genetics, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pgen.1007082
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- Publication type:
- Article
Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage.
- Published in:
- Nucleic Acids Research, 2008, v. 36, n. 17, p. 5660, doi. 10.1093/nar/gkn555
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- Publication type:
- Article
Altered dNTP pools accelerate tumor formation in mice.
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- Nucleic Acids Research, 2024, v. 52, n. 20, p. 12475, doi. 10.1093/nar/gkae843
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- Publication type:
- Article
Isocratic HPLC analysis for the simultaneous determination of dNTPs, rNTPs and ADP in biological samples.
- Published in:
- Nucleic Acids Research, 2022, v. 50, n. 3, p. e18, doi. 10.1093/nar/gkab1117
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- Publication type:
- Article
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 1, p. 264, doi. 10.1093/nar/gkz1006
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- Publication type:
- Article
The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity.
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- Nucleic Acids Research, 2019, v. 47, n. 8, p. 3986, doi. 10.1093/nar/gkz048
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- Publication type:
- Article
A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance.
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- Nucleic Acids Research, 2019, v. 47, n. 1, p. 237, doi. 10.1093/nar/gky1154
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- Publication type:
- Article
Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry.
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- Nucleic Acids Research, 2018, v. 46, n. 11, p. 1, doi. 10.1093/nar/gky203
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- Publication type:
- Article
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations.
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- Nucleic Acids Research, 2017, v. 45, n. 3, p. 1200, doi. 10.1093/nar/gkw1149
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- Publication type:
- Article
The mutation spectrum in genomic late replication domains shapes mammalian GC content.
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- Nucleic Acids Research, 2016, v. 44, n. 9, p. 4222, doi. 10.1093/nar/gkw268
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- Publication type:
- Article
Genome-wide analysis of the specificity and mechanisms of replication infidelity driven by imbalanced dNTP pools.
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- Nucleic Acids Research, 2016, v. 44, n. 4, p. 1669, doi. 10.1093/nar/gkv1298
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- Publication type:
- Article
Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups.
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- Nucleic Acids Research, 2014, v. 42, n. 10, p. 6314, doi. 10.1093/nar/gku267
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- Publication type:
- Article
Pre-activation of the genome integrity checkpoint increases DNA damage tolerance.
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- Nucleic Acids Research, 2013, v. 41, n. 22, p. 10371, doi. 10.1093/nar/gkt820
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- Article
Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools.
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- Nucleic Acids Research, 2011, v. 39, n. 4, p. 1360, doi. 10.1093/nar/gkq829
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- Publication type:
- Article
Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint.
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- Nucleic Acids Research, 2010, v. 38, n. 12, p. 3975, doi. 10.1093/nar/gkq128
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- Publication type:
- Article
Elevated dNTP levels suppress hyper-recombination in Saccharomyces cerevisiae S-phase checkpoint mutants.
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- Nucleic Acids Research, 2010, v. 38, n. 4, p. 1195, doi. 10.1093/nar/gkp1064
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- Publication type:
- Article
Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific.
- Published in:
- Nature Structural & Molecular Biology, 2015, v. 22, n. 4, p. 291, doi. 10.1038/nsmb.2989
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- Publication type:
- Article
Genome instability due to ribonucleotide incorporation into DNA.
- Published in:
- Nature Chemical Biology, 2010, v. 6, n. 10, p. 774, doi. 10.1038/nchembio.424
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- Publication type:
- Article
Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase.
- Published in:
- Molecular & Cellular Biology, 2013, v. 33, n. 16, p. 3202, doi. 10.1128/MCB.00474-13
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- Publication type:
- Article
Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase.
- Published in:
- Molecular & Cellular Biology, 2013, v. 33, n. 15, p. 3202, doi. 10.1128/MCB.00474-13
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- Publication type:
- Article
Replication Fork Collapse and Genome Instability in a Deoxycytidylate Deaminase Mutant.
- Published in:
- Molecular & Cellular Biology, 2012, v. 32, n. 21, p. 4445, doi. 10.1128/MCB.01062-12
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- Publication type:
- Article