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Predicting subgroup treatment effects for a new study: Motivations, results and learnings from running a data challenge in a pharmaceutical corporation.
- Published in:
- Pharmaceutical Statistics, 2024, v. 23, n. 4, p. 495, doi. 10.1002/pst.2368
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- Publication type:
- Article
Interim decision making in seamless trial designs: An application in an adaptive dose‐finding study in a rare kidney disease.
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- Pharmaceutical Statistics, 2024, v. 23, n. 1, p. 20, doi. 10.1002/pst.2335
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- Publication type:
- Article
Sensitivity analyses for the principal ignorability assumption using multiple imputation.
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- Pharmaceutical Statistics, 2023, v. 22, n. 1, p. 64, doi. 10.1002/pst.2260
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- Publication type:
- Article
Eliciting judgements about dependent quantities of interest: The SHeffield ELicitation Framework extension and copula methods illustrated using an asthma case study.
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- Pharmaceutical Statistics, 2022, v. 21, n. 5, p. 1005, doi. 10.1002/pst.2212
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- Publication type:
- Article
Improving the assessment of the probability of success in late stage drug development.
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- Pharmaceutical Statistics, 2022, v. 21, n. 2, p. 439, doi. 10.1002/pst.2179
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- Publication type:
- Article
Identifying treatment effect heterogeneity in dose‐finding trials using Bayesian hierarchical models.
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- Pharmaceutical Statistics, 2022, v. 21, n. 1, p. 17, doi. 10.1002/pst.2150
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- Publication type:
- Article
Principal stratum strategy: Potential role in drug development.
- Published in:
- Pharmaceutical Statistics, 2021, v. 20, n. 4, p. 737, doi. 10.1002/pst.2104
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- Publication type:
- Article
Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593‐606, Sep/Oct 2018., DOI:https://doi.org/10.1002/pst.1873
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- Pharmaceutical Statistics, 2019, v. 18, n. 3, p. 284, doi. 10.1002/pst.1942
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- Article
Model averaging for treatment effect estimation in subgroups.
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- Pharmaceutical Statistics, 2017, v. 16, n. 2, p. 133, doi. 10.1002/pst.1796
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- Publication type:
- Article
Characterization of dose-response for count data using a generalized MCP-Mod approach in an adaptive dose-ranging trial.
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- Pharmaceutical Statistics, 2015, v. 14, n. 4, p. 359, doi. 10.1002/pst.1693
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- Publication type:
- Article
Viewpoint: model selection uncertainty, pre-specification, and model averaging.
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- Pharmaceutical Statistics, 2015, v. 14, n. 2, p. 79, doi. 10.1002/pst.1671
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- Publication type:
- Article
A practical guide to Bayesian group sequential designs.
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- Pharmaceutical Statistics, 2014, v. 13, n. 1, p. 71, doi. 10.1002/pst.1593
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- Publication type:
- Article
Connecting Instrumental Variable methods for causal inference to the Estimand Framework.
- Published in:
- Statistics in Medicine, 2021, v. 40, n. 25, p. 5605, doi. 10.1002/sim.9143
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- Publication type:
- Article
Subgroup identification in dose-finding trials via model-based recursive partitioning.
- Published in:
- 2018
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- Publication type:
- journal article
Bayesian Biostatistics 2014 - Satellite conference of the International Biometric Conference.
- Published in:
- 2015
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- Publication type:
- Editorial
Practical considerations for using functional uniform prior distributions for dose-response estimation in clinical trials.
- Published in:
- Biometrical Journal, 2014, v. 56, n. 6, p. 947, doi. 10.1002/bimj.201300138
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- Publication type:
- Article
Stochastically ordered multiple regression.
- Published in:
- Biostatistics, 2010, v. 11, n. 3, p. 419, doi. 10.1093/biostatistics/kxq001
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- Publication type:
- Article
Bayesian inference for a principal stratum estimand on recurrent events truncated by death.
- Published in:
- Biometrics, 2023, v. 79, n. 4, p. 3792, doi. 10.1111/biom.13831
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- Publication type:
- Article
Likelihood ratio tests for a dose-response effect using multiple nonlinear regression models.
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- Biometrics, 2017, v. 73, n. 1, p. 197, doi. 10.1111/biom.12563
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- Publication type:
- Article
Unimodal regression using Bernstein-Schoenberg splines and penalties.
- Published in:
- Biometrics, 2014, v. 70, n. 4, p. 783, doi. 10.1111/biom.12193
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- Publication type:
- Article
Functional Uniform Priors for Nonlinear Modeling.
- Published in:
- Biometrics, 2012, v. 68, n. 3, p. 893, doi. 10.1111/j.1541-0420.2012.01747.x
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- Publication type:
- Article
Bayesian Nonparametric Estimation of Continuous Monotone Functions with Applications to Dose–Response Analysis.
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- Biometrics, 2009, v. 65, n. 1, p. 198, doi. 10.1111/j.1541-0420.2008.01060.x
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- Publication type:
- Article
Model selection versus model averaging in dose finding studies.
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- 2016
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- Publication type:
- journal article
Model-based dose finding under model uncertainty using general parametric models.
- Published in:
- Statistics in Medicine, 2014, v. 33, n. 10, p. 1646, doi. 10.1002/sim.6052
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- Publication type:
- Article
On the efficiency of two-stage response-adaptive designs.
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- Statistics in Medicine, 2013, v. 32, n. 10, p. 1646, doi. 10.1002/sim.5555
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- Publication type:
- Article
Calculating quantiles of noisy distribution functions using local linear regressions.
- Published in:
- Computational Statistics, 2018, v. 33, n. 1, p. 487, doi. 10.1007/s00180-017-0736-0
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- Publication type:
- Article
A New Comprehensive Approach to Assess the Probability of Success of Development Programs Before Pivotal Trials.
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- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1050, doi. 10.1002/cpt.2488
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- Publication type:
- Article
Comparing algorithms for characterizing treatment effect heterogeneity in randomized trials.
- Published in:
- Biometrical Journal, 2024, v. 66, n. 1, p. 1, doi. 10.1002/bimj.202100337
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- Publication type:
- Article
A multiple comparison procedure for dose‐finding trials with subpopulations.
- Published in:
- Biometrical Journal, 2020, v. 62, n. 1, p. 53, doi. 10.1002/bimj.201800111
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- Publication type:
- Article
A framework to guide dose & regimen strategy for clinical drug development.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 11, p. 1276, doi. 10.1002/psp4.12701
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- Publication type:
- Article
Estimands—What they are and why they are important for pharmacometricians.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 4, p. 279, doi. 10.1002/psp4.12617
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- Publication type:
- Article
A Longitudinal Item Response Theory Model to Characterize Cognition Over Time in Elderly Subjects.
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- CPT: Pharmacometrics & Systems Pharmacology, 2017, v. 6, n. 9, p. 635, doi. 10.1002/psp4.12219
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- Publication type:
- Article
Exposure-response modelling approaches for determining optimal dosing rules in children.
- Published in:
- 2020
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- Publication type:
- journal article
Testing multiple dose combinations in clinical trials.
- Published in:
- 2020
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- Publication type:
- journal article
G. Parmigiani and L. Inoue: Decision theory-principles and approaches.
- Published in:
- 2011
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- Publication type:
- Book Review
Anirban DasGupta: Asymptotic theory of statistics and probability.
- Published in:
- 2010
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- Publication type:
- Book Review