Works matching AU Bijnens, Luc

Results: 47

A web application for sample size and power calculation in case-control microbiome studies.

Published in:

Bioinformatics, 2016, v. 32, n. 13, p. 2038, doi. 10.1093/bioinformatics/btw099

By:

Mattiello, Federico;
Verbist, Bie;
Faust, Karoline;
Raes, Jeroen;
Shannon, William D.;
Bijnens, Luc;
Thas, Olivier

Publication type:

Article

FABIA: factor analysis for bicluster acquisition.

Published in:

Bioinformatics, 2010, v. 26, n. 12, p. 1520, doi. 10.1093/bioinformatics/btq227

By:

Hochreiter, Sepp;
Bodenhofer, Ulrich;
Heusel, Martin;
Mayr, Andreas;
Mitterecker, Andreas;
Kasim, Adetayo;
Khamiakova, Tatsiana;
Van Sanden, Suzy;
Lin, Dan;
Talloen, Willem;
Bijnens, Luc;
Göhlmann, Hinrich W. H.;
Shkedy, Ziv;
Clevert, Djork-Arné

Publication type:

Article

I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data.

Published in:

Bioinformatics, 2007, v. 23, n. 21, p. 2897, doi. 10.1093/bioinformatics/btm478

By:

Willem Talloen;
Djork-ArnÃ© Clevert;
Sepp Hochreiter;
Dhammika Amaratunga;
Luc Bijnens;
Stefan Kass;
Hinrich W.H. GÃ¶hlmann

Publication type:

Article

A unified framework for unconstrained and constrained ordination of microbiome read count data.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0205474

By:

Hawinkel, Stijn;
Kerckhof, Frederiek-Maarten;
Bijnens, Luc;
Thas, Olivier

Publication type:

Article

A Modeling Approach to the Analysis of Nerve Regenerative Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2006, v. 16, n. 6, p. 843, doi. 10.1080/10543400600795384

By:

Sanden, SuzyVan;
Wouters, Luc;
Burzykowski, Tomasz;
Molenberghs, Geert;
Remoortere, MarieVan;
Meert, Theo;
Bijnens, Luc

Publication type:

Article

Teaching Statistical Thinking to Life Scientists a Case-Based Approach.

Published in:

Journal of Biopharmaceutical Statistics, 2006, v. 16, n. 1, p. 61, doi. 10.1080/10543400500406520

By:

Vandenbroeck, Philippe;
Wouters, Luc;
Molenberghs, Geert;
Gestel, JefVan;
Bijnens, Luc

Publication type:

Article

A HIERARCHICAL BINOMIAL-POISSON MODEL FOR THE ANALYSIS OF A CROSSOVER DESIGN FOR CORRELATED BINARY DATA WHEN THE NUMBER OF TRIALS IS DOSE-DEPENDENT.

Published in:

Journal of Biopharmaceutical Statistics, 2005, v. 15, n. 2, p. 225, doi. 10.1081/BIP-200049825

By:

Shkedy, Ziv;
Molenberghs, Geert;
Craenendonck, Hansfried Van;
Steckler, Thomas;
Bijnens, Luc

Publication type:

Article

MODELING ANTI-KLH ELISA DATA USING TWO-STAGE AND MIXED EFFECTS MODELS IN SUPPORT OF IMMUNOTOXICOLOGICAL STUDIES.

Published in:

Journal of Biopharmaceutical Statistics, 2005, v. 15, n. 2, p. 205, doi. 10.1081/BIP-200048815

By:

Shkedy, Ziv;
Straetemans, Roel;
Molenberghs, Geert;
Desmidt, Miek;
Vinken, Petra;
Goeminne, Nick;
Coussement, Werner;
Poel, Bob Van Den;
Bijnens, Luc

Publication type:

Article

Conserving the endemic birds on the Comoro Islands, III: bird diversity and habitat selection on Ngazidja.

Published in:

Bird Conservation International, 1995, v. 5, n. 4, p. 463, doi. 10.1017/S0959270900001180

By:

Stevens, Jan;
Louette, Michel;
Bijnens, Luc;
Herremans, Marc

Publication type:

Article

A Comparison of Procedures for Controlling the False Discovery Rate in the Presence of Small Variance Genes: A Simulation Study.

Published in:

Communications in Statistics: Simulation & Computation, 2009, v. 38, n. 10, p. 2111, doi. 10.1080/03610910903249510

By:

Lin, Dan;
Shkedy, Ziv;
Burzykowski, Tomasz;
Talloen, Willem;
Bijnens, Luc

Publication type:

Article

ViVaMBC: estimating viral sequence variation in complex populations from illumina deep-sequencing data using model-based clustering.

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0458-7

By:

Verbist, Bie;
Clement, Lieven;
Reumers, Joke;
Thys, Kim;
Vapirev, Alexander;
Talloen, Willem;
Wetzels, Yves;
Meys, Joris;
Aerssens, Jeroen;
Bijnens, Luc;
Thas, Olivier

Publication type:

Article

ViVaMBC: estimating viral sequence variation in complex populations from illumina deep-sequencing data using model-based clustering.

Published in:

BMC Bioinformatics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12859-015-0458-7

By:

Verbist, Bie;
Clement, Lieven;
Reumers, Joke;
KimThys;
Vapirev, Alexander;
Talloen, Willem;
Yves Wetzels;
Joris Meys;
Aerssens, Jeroen;
Bijnens, Luc;
Olivier Thas

Publication type:

Article

Informative or Noninformative Calls for Gene Expression: A Latent Variable Approach.

Published in:

Statistical Applications in Genetics & Molecular Biology, 2010, v. 9, n. 1, p. 1, doi. 10.2202/1544-6115.1460

By:

Kasim, Adetayo;
Dan Lin;
Van Sanden, Suzy;
Clevert, Djork-Arné;
Bijnens, Luc;
Göhlmann, Hinrich;
Amaratunga, Dhammika;
Hochreiter, Sepp;
Shkedy, Ziv;
Talloen, Willem

Publication type:

Article

Post‐operative incidence of lymphedema after RARP with or without extended pelvic lymph node dissection in a cohort study.

Published in:

BJUI Compass, 2025, v. 6, n. 1, p. 1, doi. 10.1002/bco2.466

By:

Clinckaert, Andries;
Ysenbaardt, Laura;
Bijnens, Annabel;
Van Calster, Charlotte;
Geraerts, Inge;
Joniau, Steven;
Devoogdt, Nele;
Bijnens, Luc;
Everaerts, Wouter

Publication type:

Article

High dimensional surrogacy: computational aspects of an upscaled analysis.

Published in:

Journal of Biopharmaceutical Statistics, 2020, v. 30, n. 1, p. 104, doi. 10.1080/10543406.2019.1657128

By:

Sengupta, Rudradev;
Perualila, Nolen Joy;
Shkedy, Ziv;
Biecek, Przemyslaw;
Molenberghs, Geert;
Bijnens, Luc

Publication type:

Article

Genomic Biomarkers for a Binary Clinical Outcome in Early Drug Development Microarray Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2012, v. 22, n. 1, p. 72, doi. 10.1080/10543406.2010.504906

By:

Van Sanden, Suzy;
Shkedy, Ziv;
Burzykowski, Tomasz;
Göhlmann, HinrichW. H.;
Talloen, Willem;
Bijnens, Luc

Publication type:

Article

A Latent Pharmacokinetic Time Profile to Model Dose-Response Survival Data.

Published in:

Journal of Biopharmaceutical Statistics, 2010, v. 20, n. 4, p. 759, doi. 10.1080/10543401003618249

By:

Jacobs, Tom;
Straetemans, Roel;
Molenberghs, Geert;
Adriaan Bouwknecht, J.;
Bijnens, Luc

Publication type:

Article

Correction for Model Selection Bias Using a Modified Model Averaging Approach for Supervised Learning Methods Applied to EEG Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2010, v. 20, n. 4, p. 768, doi. 10.1080/10543401003618744

By:

Wouters, Kristien;
Abrahantes, JoséCortiñas;
Molenberghs, Geert;
Geys, Helena;
Ahnaou, Abdellah;
Drinkenburg, WilhelmusH. I. M.;
Bijnens, Luc

Publication type:

Article

Investigating Association Between Behavior, Corticosterone, Heart Rate, and Blood Pressure in Rats Using Surrogate Marker Evaluation Methodology.

Published in:

Journal of Biopharmaceutical Statistics, 2009, v. 19, n. 1, p. 133, doi. 10.1080/10543400802527924

By:

Tilahun, Abel;
Maringwa, JohnT.;
Geys, Helena;
Alonso, Ariel;
Raeymaekers, Leen;
Molenberghs, Geert;
Kieboom, GerdVan Den;
Drinkenburg, Pim;
Bijnens, Luc

Publication type:

Article

Combined Models for Data from In Vitro-In Vivo Correlation Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2008, v. 18, n. 6, p. 1197, doi. 10.1080/10543400802369061

By:

Jacobs, Tom;
Rossenu, Stefaan;
Dunne, Adrian;
Molenberghs, Geert;
Straetemans, Roel;
Bijnens, Luc

Publication type:

Article

Application of Semiparametric Mixed Models and Simultaneous Confidence Bands in a Cardiovascular Safety Experiment with Longitudinal Data.

Published in:

Journal of Biopharmaceutical Statistics, 2008, v. 18, n. 6, p. 1043, doi. 10.1080/10543400802368881

By:

Maringwa, JohnT.;
Geys, Helena;
Shkedy, Ziv;
Faes, Christel;
Molenberghs, Geert;
Aerts, Marc;
Ammel, KarelVan;
Teisman, Ard;
Bijnens, Luc

Publication type:

Article

A Comparison of Doubly Hierarchical Discriminant Analyses for Multiple Class Longitudinal Data from EEG Experiments.

Published in:

Journal of Biopharmaceutical Statistics, 2008, v. 18, n. 6, p. 1120, doi. 10.1080/10543400802369111

By:

Wouters, Kristien;
Abrahantes, JoséCortiñas;
Molenberghs, Geert;
Ahnaou, Abdellah;
Drinkenburg, WilhelmusH. I. M.;
Bijnens, Luc

Publication type:

Article

broken promise: microbiome differential abundance methods do not control the false discovery rate.

Published in:

Briefings in Bioinformatics, 2019, v. 20, n. 1, p. 210, doi. 10.1093/bib/bbx104

By:

Hawinkel, Stijn;
Mattiello, Federico;
Bijnens, Luc;
Thas, Olivier

Publication type:

Article

Statistical detection of synergy: New methods and a comparative study.

Published in:

Pharmaceutical Statistics, 2022, v. 21, n. 2, p. 345, doi. 10.1002/pst.2173

By:

Thas, Olivier;
Tourny, Annelies;
Verbist, Bie;
Hawinkel, Stijn;
Nazarov, Maxim;
Mutambanengwe, Kathy;
Bijnens, Luc

Publication type:

Article

Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593‐606, Sep/Oct 2018., DOI:https://doi.org/10.1002/pst.1873

Published in:

Pharmaceutical Statistics, 2019, v. 18, n. 3, p. 284, doi. 10.1002/pst.1942

By:

Jaki, Thomas;
Gordon, Allan;
Forster, Pamela;
Bijnens, Luc;
Bornkamp, Bjoern;
Brannath, Werner;
Fontana, Roberto;
Gasparini, Mauro;
Hampson, Lisa V.;
Jacobs, Tom;
Jones, Byron;
Paoletti, Xavier;
Posch, Martin;
Titman, Andrew;
Vonk, Richardus;
Koenig, Franz

Publication type:

Article

Impact of selection bias on the evaluation of clusters of chemical compounds in the drug discovery process.

Published in:

Pharmaceutical Statistics, 2015, v. 14, n. 2, p. 129, doi. 10.1002/pst.1665

By:

Alonso, Ariel;
Milanzi, Elasma;
Molenberghs, Geert;
Buyck, Christophe;
Bijnens, Luc

Publication type:

Article

A new modeling approach for quantifying expert opinion in the drug discovery process.

Published in:

Statistics in Medicine, 2015, v. 34, n. 9, p. 1590, doi. 10.1002/sim.6459

By:

Alonso, Ariel;
Milanzi, Elasma;
Molenberghs, Geert;
Buyck, Christophe;
Bijnens, Luc

Publication type:

Article

Validation of a longitudinally measured surrogate marker for a time-to-event endpoint.

Published in:

Journal of Applied Statistics, 2003, v. 30, n. 2, p. 235, doi. 10.1080/0266476022000023776

By:

Renard, Didier;
Geys, Helena;
Molenberghs, Geert;
Burzykowski, Tomasz;
Buyse, Marc;
Vangeneugden, Tony;
Bijnens, Luc

Publication type:

Article

Including Information on the Therapeutic Window in Bioequivalence Acceptance.

Published in:

Pharmaceutical Research, 2008, v. 25, n. 11, p. 2628, doi. 10.1007/s11095-008-9680-6

By:

Tom Jacobs;
Filip De Ridder;
Sarah Rusch;
Achiel Van Peer;
Luc Bijnens

Publication type:

Article

Univariate Versus Multivariate Surrogates in the Single-Trial Setting.

Published in:

Statistics in Biopharmaceutical Research, 2019, v. 11, n. 3, p. 301, doi. 10.1080/19466315.2019.1575276

By:

Van der Elst, Wim;
Alonso, Ariel Abad;
Geys, Helena;
Meyvisch, Paul;
Bijnens, Luc;
Sengupta, Rudradev;
Molenberghs, Geert

Publication type:

Article

Dose–Response Modeling Under Simple Order Restrictions Using Bayesian Variable Selection Methods.

Published in:

Statistics in Biopharmaceutical Research, 2014, v. 6, n. 3, p. 252, doi. 10.1080/19466315.2013.855472

By:

Otava, Martin;
Shkedy, Ziv;
Lin, Dan;
Göhlmann, Hinrich W. H.;
Bijnens, Luc;
Talloen, Willem;
Kasim, Adetayo

Publication type:

Article

A Meta-Analytical Framework to Include Historical Data in Allometric Scaling.

Published in:

Statistics in Biopharmaceutical Research, 2012, v. 4, n. 2, p. 205, doi. 10.1080/19466315.2012.707493

By:

Bijnens, Luc;
Van den Bergh, An;
Sinha, Vikash;
Geys, Helena;
Molenberghs, Geert;
Verbeke, Tobias;
Kasim, Adetayo;
Straetemans, Roel;
De Ridder, Filip;
Balmain-Mackie, Claire

Publication type:

Article

Analysis of cross-over designs with serial correlation within periods using semi-parametric mixed models.

Published in:

Statistics in Medicine, 2008, v. 27, n. 28, p. 6009, doi. 10.1002/sim.3363

By:

Maringwa, John T.;
Geys, Helena;
Shkedy, Ziv;
Faes, Christel;
Molenberghs, Geert;
Aerts, Marc;
Van Ammel, Karel;
Teisman, Ard;
Bijnens, Luc

Publication type:

Article

A high-dimensional joint model for longitudinal outcomes of different nature.

Published in:

Statistics in Medicine, 2008, v. 27, n. 22, p. 4408, doi. 10.1002/sim.3314

By:

Faes, Christel;
Aerts, Marc;
Molenberghs, Geert;
Geys, Helena;
Teuns, Greet;
Bijnens, Luc

Publication type:

Article

Controlling type I error rate for fast track drug development programmes.

Published in:

Statistics in Medicine, 2003, v. 22, n. 5, p. 665, doi. 10.1002/sim.1396

By:

Shih, Weichung J.;
Ouyang, Peter;
Quan, Hui;
Lin, Yong;
Michiels, Bart;
Bijnens, Luc

Publication type:

Article

Selection models and pattern-mixture models to analyse longitudinal quality of life data subject to drop-out.

Published in:

2002

By:

Michiels, Bart;
Molenberghs, Geert;
Bijnens, Luc;
Vangeneugden, Tony;
Thijs, Herbert

Publication type:

journal article

A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00531-6

By:

Ruiz, Victoria E.;
Battaglia, Thomas;
Kurtz, Zachary D.;
Bijnens, Luc;
Ou, Amy;
Engstrand, Isak;
Xuhui Zheng;
Iizumi, Tadasu;
Mullins, Briana J.;
Müller, Christian L.;
Cadwell, Ken;
Bonneau, Richard;
Perez-Perez, Guillermo I.;
Blaser, Martin J.

Publication type:

Article

Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.

Published in:

Alzheimer's Research & Therapy, 2018, v. 10, p. 1, doi. 10.1186/s13195-017-0329-8

By:

Praet, Jelle;
Manyakov, Nikolay V.;
Muchene, Leacky;
Mai, Zhenhua;
Terzopoulos, Vasilis;
de Backer, Steve;
Torremans, An;
Guns, Pieter-Jan;
Van De Casteele, Tom;
Bottelbergs, Astrid;
Van Broeck, Bianca;
Sijbers, Jan;
Smeets, Dirk;
Shkedy, Ziv;
Bijnens, Luc;
Pemberton, Darrel J.;
Schmidt, Mark E.;
Van der Linden, Annemie;
Verhoye, Marleen

Publication type:

Article

GLMM approach to study the spatial and temporal evolution of spikes in the small intestine.

Published in:

Statistical Modelling: An International Journal, 2006, v. 6, n. 4, p. 300, doi. 10.1177/1471082006071851

By:

Faes, Christel;
Aerts, Marc;
Geys, Helena;
Bijnens, Luc;
Donck, Luc Ver;
Lammers, Wim J. E. P.

Publication type:

Article

Sequence count data are poorly fit by the negative binomial distribution.

Published in:

PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0224909

By:

Hawinkel, Stijn;
Rayner, J. C. W.;
Bijnens, Luc;
Thas, Olivier

Publication type:

Article

The authors replied as follows:.

Published in:

Biometrics, 2005, v. 61, n. 2, p. 632, doi. 10.1111/j.1541-0420.2005.00367.x

By:

Wouters, Luc;
Göhlmann, Hinrich W.;
Bijnens, Luc;
Kass, Stefan U.;
Molenberghs, Geert;
Lewi, Paul J.

Publication type:

Article

Graphical Exploration of Gene Expression Data:A Comparative Study of Three Multivariate Methods.

Published in:

Biometrics, 2003, v. 59, n. 4, p. 1131, doi. 10.1111/j.0006-341X.2003.00130.x

By:

Wouters, Luc;
Gouml;hlmann, Hinrich W.;
Bijnens, Luc;
Kass, Stefan U.;
Molenberghs, Geert;
Lewi, Paul J.

Publication type:

Article

Behavioral Testing of Antidepressant Compounds: An Analysis of Crossover Design for Correlated Binary Data.

Published in:

Biometrical Journal, 2005, v. 47, n. 3, p. 286

By:

Ziv Shkedy;
Veerle Vandersmissen;
Geert Molenberghs;
Hansfried Van Craenendonck;
Nancy Aerts;
Thomas Steckler;
Luc Bijnens

Publication type:

Article

Design and Analysis of Drug Combination Experiments.

Published in:

Biometrical Journal, 2005, v. 47, n. 3, p. 299

By:

Roel Straetemans;
Timothy O'Brien;
Luc Wouters;
Jacky Van Dun;
Michel Janicot;
Luc Bijnens;
Tomasz Burzykowski;
Marc Aerts

Publication type:

Article

Psychotropic drug classification based on sleep–wake behaviour of rats.

Published in:

Journal of the Royal Statistical Society: Series C (Applied Statistics), 2007, v. 56, n. 2, p. 223, doi. 10.1111/j.1467-9876.2007.00575.x

By:

Wouters, Kristien;
Ahnaou, Abdellah;
Abrahantes, Jose Cortinas;
Molenberghs, Geert;
Geys, Helena;
Bijnens, Luc;
Drinkenburg, Wilhelmus H. I. M.

Publication type:

Article

Prediction of human oral plasma concentration-time profiles using preclinical data: comparative evaluation of prediction approaches in early pharmaceutical discovery.

Published in:

2011

By:

Van den Bergh A;
Sinha V;
Gilissen R;
Straetemans R;
Wuyts K;
Morrison D;
Bijnens L;
Mackie C;
Van den Bergh, An;
Sinha, Vikash;
Gilissen, Ron;
Straetemans, Roel;
Wuyts, Koen;
Morrison, Denise;
Bijnens, Luc;
Mackie, Claire

Publication type:

journal article

Prediction of Human Oral Plasma Concentration-Time Profiles Using Preclinical Data.

Published in:

Clinical Pharmacokinetics, 2011, v. 50, n. 8, p. 505, doi. 10.2165/11587230-000000000-00000

By:

den Bergh, An Van;
Sinha, Vikash;
Gilissen, Ron;
Straetemans, Roel;
Wuyts, Koen;
Morrison, Denise;
Bijnens, Luc;
Mackie, Claire

Publication type:

Article