Works by Bacha, Abir Ben

Results: 67

New Nitrogen-, Oxygen-, and Sulfur-Containing Heterocyclic Compounds as Anti-Colon Cancer Agents: Synthesis, Multitargeted Evaluations, Molecular Docking Simulations and ADMET Predictions.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 801, doi. 10.3390/ph18060801

By:

El-Sayed, Nahed Nasser Eid;
Krayem, Najeh;
Derbala, Hamed Ahmed;
Kamal, Shimaa;
Bukhari, Syde Nasir Abbas;
El-Ashrey, Mohamed K.;
Almarhoon, Zainab M.;
Soliman Alterary, Seham;
Ben Bacha, Abir

Publication type:

Article

Combining ROC Curves to Improve Diagnostic Values for Vitamin D3 and Chloride Co-Transporters in Connection to Epilepsy and Sleep Problems, Comorbidities in Autism Spectrum Disorders.

Published in:

Clinical & Translational Neuroscience, 2025, v. 9, n. 2, p. 21, doi. 10.3390/ctn9020021

By:

El-Ansary, Afaf;
Alabdali, Altaf;
Ben Bacha, Abir;
Alonazi, Mona;
Al-Ayadhi, Laila Y.

Publication type:

Article

Cytotoxic effects of Annona squamosa leaves against breast cancer cells via apoptotic signaling proteins.

Published in:

Journal of King Saud University - Science, 2022, v. 34, n. 4, p. N.PAG, doi. 10.1016/j.jksus.2022.102013

By:

Al-Nemari, Rawan;
Bacha, Abir Ben;
Al-Senaidy, Abdulrahman;
Almutairi, Mikhlid H.;
Arafah, Maha;
Al-Saran, Hadel;
Abutaha, Nael;
Semlali, Abdelhabib

Publication type:

Article

Impact of GABA and nutritional supplements on neurochemical biomarkers in autism: a PPA rodent model study.

Published in:

Frontiers in Molecular Neuroscience, 2025, p. 1, doi. 10.3389/fnmol.2025.1553438

By:

Alabdali, Altaf N.;
Ben Bacha, Abir;
Alonazi, Mona;
Abuaish, Sameera;
Almotairi, Ahmad;
Al-Ayadhi, Laila;
El-Ansary, Afaf K.

Publication type:

Article

Synthesis, X-ray Structure, Conformational Analysis, and DFT Studies of a Giant s -Triazine bis -Schiff Base.

Published in:

Crystals (2073-4352), 2021, v. 11, n. 11, p. 1418, doi. 10.3390/cryst11111418

By:

Almarhoon, Zainab M.;
Al-Zaben, Maha I.;
Ben Bacha, Abir;
Haukka, Matti;
El-Faham, Ayman;
Soliman, Saied M.

Publication type:

Article

Nanotherapy for Cancer and Biological Activities of Green Synthesized AgNPs Using Aqueous Saussurea costus Leaves and Roots Extracts.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 10, p. 1371, doi. 10.3390/ph17101371

By:

Almayouf, Mina A.;
Charguia, Raihane;
Awad, Manal A.;
Ben Bacha, Abir;
Ben Abdelmalek, Imen

Publication type:

Article

Synthesis and Biological Evaluation of Some New 3-Aryl-2-thioxo-2,3-dihydroquinazolin-4(1 H)-ones and 3-Aryl-2-(benzylthio)quinazolin-4(3 H)-ones as Antioxidants; COX-2, LDHA, α-Glucosidase and α-Amylase Inhibitors; and Anti-Colon Carcinoma and Apoptosis-Inducing Agents

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 10, p. 1392, doi. 10.3390/ph16101392

By:

El-Sayed, Nahed Nasser Eid;
Al-Otaibi, Taghreed M.;
Barakat, Assem;
Almarhoon, Zainab M.;
Hassan, Mohd. Zaheen;
Al-Zaben, Maha I.;
Krayem, Najeh;
Masand, Vijay H.;
Ben Bacha, Abir

Publication type:

Article

Synthesis and Evaluation of Some New 4 H -Pyran Derivatives as Antioxidant, Antibacterial and Anti-HCT-116 Cells of CRC, with Molecular Docking, Antiproliferative, Apoptotic and ADME Investigations.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 7, p. N.PAG, doi. 10.3390/ph15070891

By:

El-Sayed, Nahed N. E.;
Zaki, Magdi E. A.;
Al-Hussain, Sami A.;
Ben Bacha, Abir;
Berredjem, Malika;
Masand, Vijay H.;
Almarhoon, Zainab M.;
Omar, Hanaa S.

Publication type:

Article

Cytotoxic, Antioxidant, and Metabolic Enzyme Inhibitory Activities of Euphorbia cyparissias Extracts.

Published in:

Oxidative Medicine & Cellular Longevity, 2020, p. 1, doi. 10.1155/2020/9835167

By:

Alonazi, Mona;
Horchani, Habib;
Alwhibi, Mona;
Ben Bacha, Abir

Publication type:

Article

Cytotoxic, Antioxidant, and Metabolic Enzyme Inhibitory Activities of Euphorbia cyparissias Extracts.

Published in:

Oxidative Medicine & Cellular Longevity, 2020, p. 1, doi. 10.1155/2020/9835167

By:

Alonazi, Mona;
Horchani, Habib;
Alwhibi, Mona;
Bacha, Abir Ben

Publication type:

Article

Hydrolysis of oils in the Wadi Hanifah River in Saudi Arabia by free and immobilized Staphylococcus aureus ALA1 lipase.

Published in:

Environmental Progress & Sustainable Energy, 2019, v. 38, n. 3, p. N.PAG, doi. 10.1002/ep.13000

By:

Bacha, Abir Ben;
Abid, Islem;
Nehdi, Imededdine;
Horchani, Habib

Publication type:

Article

Preliminary evaluation of a novel nine-biomarker profile for the prediction of autism spectrum disorder.

Published in:

PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0227626

By:

El-Ansary, Afaf;
Hassan, Wail M.;
Daghestani, Maha;
Al-Ayadhi, Laila;
Ben Bacha, Abir

Publication type:

Article

Purification and Biochemical Characterization of an Organic-Solvent-Tolerant Thioredoxin from Dromedary Pancreas.

Published in:

Protein Journal, 2012, v. 31, n. 1, p. 1, doi. 10.1007/s10930-011-9366-5

By:

Ben Bacha, Abir;
Mejdoub, Hafedh

Publication type:

Article

Biochemical and molecular characterization of purified chicken pancreatic phospholipase A<sub>2</sub>.

Published in:

FEBS Journal, 2009, v. 276, n. 16, p. 4545, doi. 10.1111/j.1742-4658.2009.07160.x

By:

Karray, Aida;
Frikha, Fakher;
Bacha, Abir Ben;
Ali, Yassine Ben;
Gargouri, Youssef;
Bezzine, Sofiane

Publication type:

Article

Synthesis, molecular modelling, and biological evaluation of novel quinoxaline derivatives for treating type II diabetes.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2395985

By:

Alasmary, Fatmah Ali S.;
Abdullah, Dalal A.;
Masand, Vijay H.;
Ben Bacha, Abir;
Omar Ebeid, Abdelsattar Mansour;
El-Araby, Moustafa E.;
Alafeefy, Ahmed M

Publication type:

Article

Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 672, doi. 10.1080/14756366.2019.1574780

By:

El-Sayed, Nahed N. E.;
Almaneai, Norah M.;
Ben Bacha, Abir;
Al-Obeed, Omar;
Ahmad, Rehan;
Abdulla, Maha;
Alafeefy, Ahmed M.

Publication type:

Article

New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 1143, doi. 10.1080/14756366.2017.1363743

By:

Alasmary, Fatmah A. S.;
Alnahdi, Fatima S.;
Ben Bacha, Abir;
El-Araby, Amr M.;
Moubayed, Nadine;
Alafeefy, Ahmed M.;
El-Araby, Moustafa E.

Publication type:

Article

Bee Pollen and Probiotics' Potential to Protect and Treat Intestinal Permeability in Propionic Acid-Induced Rodent Model of Autism.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 4, p. 548, doi. 10.3390/metabo13040548

By:

Alonazi, Mona;
Ben Bacha, Abir;
Alharbi, Mona G.;
Khayyat, Arwa Ishaq A.;
AL-Ayadhi, Laila;
El-Ansary, Afaf

Publication type:

Article

Independent and Combined Effects of Probiotics and Prebiotics as Supplements or Food-Rich Diets on a Propionic-Acid-Induced Rodent Model of Autism Spectrum Disorder.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 1, p. 50, doi. 10.3390/metabo13010050

By:

Alsubaiei, Sana Razhan M.;
Alfawaz, Hanan A.;
Almubarak, Abdullah Yaseen;
Alabdali, Nouf Ahmed;
Ben Bacha, Abir;
El-Ansary, Afaf

Publication type:

Article

An organic solvent-stable lipase from a newly isolated Staphylococcus aureus ALA1 strain with potential for use as an industrial biocatalyst.

Published in:

Biotechnology & Applied Biochemistry, 2016, v. 63, n. 3, p. 378, doi. 10.1002/bab.1381

By:

Ben Bacha, Abir;
Moubayed, Nadine MS;
Al‐Assaf, Alaa

Publication type:

Article

Etiology of autistic features: the persisting neurotoxic effects of propionic acid.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 74, doi. 10.1186/1742-2094-9-74

By:

El-Ansary, Afaf K.;
Ben Bacha, Abir;
Kotb, Malak

Publication type:

Article

GC-MS profiling and assessment of antioxidant, antibacterial, and anticancer properties of extracts of Annona squamosa L. leaves.

Published in:

BMC Complementary Medicine & Therapies, 2020, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12906-020-03029-9

By:

Al-Nemari, Rawan;
Al-Senaidy, Abdulrahman;
Semlali, Abdelhabib;
Ismael, Mohammad;
Badjah-Hadj-Ahmed, Ahmed Yacine;
Ben Bacha, Abir

Publication type:

Article

Versatile biocatalyst: lipase from Streptomyces gobitricini for ester synthesis and detergent innovation.

Published in:

Frontiers in Bioengineering & Biotechnology, 2025, p. 1, doi. 10.3389/fbioe.2025.1589087

By:

Alzahrani, Areej Ali;
Krayem, Najeh;
Alonazi, Mona;
Al-Ghamdi, Jihan M.;
Horchani, Habib;
Ben Bacha, Abir

Publication type:

Article

Corrigendum: Unlocking the therapeutic potential of Saussurea costus : purification and functional characterization of α-amylase inhibitors.

Published in:

2025

By:

Ben Abdelmalek, Imen;
Alhmdi, Tomather A. A.;
Ben Bacha, Abir;
Krayem, Najeh

Publication type:

Correction Notice

Unlocking the therapeutic potential of Saussurea costus : purification and functional characterization of α-amylase inhibitors.

Published in:

Frontiers in Bioengineering & Biotechnology, 2025, p. 1, doi. 10.3389/fbioe.2025.1535751

By:

Ben Abdelmalek, Imen;
Alhmdi, Tomather A. A.;
Ben Bacha, Abir;
Krayem, Najeh

Publication type:

Article

Unlocking the therapeutic potential of Saussurea costus : purification and functional characterization of α-amylase inhibitors.

Published in:

Frontiers in Bioengineering & Biotechnology, 2025, p. 1, doi. 10.3389/fbioe.2025.1535751

By:

Ben Abdelmalek, Imen;
Alhmdi, Tomather A. A.;
Ben Bacha, Abir;
Krayem, Najeh

Publication type:

Article

The anti‐inflammatory and antiapoptotic effects of probiotic on induced neurotoxicity in juvenile hamsters.

Published in:

Food Science & Nutrition, 2021, v. 9, n. 9, p. 4874, doi. 10.1002/fsn3.2435

By:

Ben Bacha, Abir;
Al‐Orf, Norah;
Alonazi, Mona;
Bhat, Ramesa Shafi;
El‐Ansary, Afaf

Publication type:

Article

Testing the combined effects of probiotics and prebiotics against neurotoxic effects of propionic acid orally administered to rat pups.

Published in:

Food Science & Nutrition, 2021, v. 9, n. 8, p. 4440, doi. 10.1002/fsn3.2418

By:

Al Suhaibani, Anwar;
Ben Bacha, Abir;
Alonazi, Mona;
Bhat, Ramesa Shafi;
El‐Ansary, Afaf

Publication type:

Article

Combining Anti-Mitochondrial Antibodies, Anti-Histone, and PLA2/COX Biomarkers to Increase Their Diagnostic Accuracy for Autism Spectrum Disorders.

Published in:

Brain Sciences (2076-3425), 2024, v. 14, n. 6, p. 576, doi. 10.3390/brainsci14060576

By:

El-Ansary, Afaf;
Alfawaz, Hanan A.;
Bacha, Abir Ben;
Al-Ayadhi, Laila Y.

Publication type:

Article

Synthesis, Structural Investigation, Antiphospholipases, Antiproteases and Antimicrobial Activities of 2-(4-hydroxy-3-methoxy-benzylidene)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one and 4-(4-hydroxy-3-methoxy-phenyl)-8-methoxy-3,4,5,6-tetrahydro-1H-benzo[h]quinazoline-2-thione

Published in:

Journal of the Chemical Society of Pakistan, 2019, v. 41, n. 6, p. 1074

By:

El-Sayed, Nahed N. E.;
Almaneai, Norah M.;
Soliman, Saied M.;
Bacha, Abir Ben;
Ghabbour, Hazem A.

Publication type:

Article

Involvement of Autophagy and Oxidative Stress-Mediated DNA Hypomethylation in Transgenerational Nephrotoxicity Induced in Rats by the Mycotoxin Fumonisin B1.

Published in:

Toxins, 2023, v. 15, n. 11, p. 663, doi. 10.3390/toxins15110663

By:

Aldawood, Nouf;
Almustafa, Sarah;
Alwasel, Saleh;
Aldahmash, Waleed;
Ben Bacha, Abir;
Alamri, Abdullah;
Alanazi, Mohammad;
Harrath, Abdel Halim

Publication type:

Article

A novel study on amyloid β peptide 40, 42 and 40/42 ratio in Saudi autistics.

Published in:

Behavioral & Brain Functions, 2012, v. 8, n. 1, p. 1, doi. 10.1186/1744-9081-8-4

By:

Al-Ayadhi, Laila Y.;
Bacha, Abir G. Ben;
Kotb, Malak;
El-Ansary, Afaf K.

Publication type:

Article

Unveiling sex-based differences in developing propionic acid-induced features in mice as a rodent model of ASD.

Published in:

PeerJ, 2023, p. 1, doi. 10.7717/peerj.15488

By:

Kamalmaz, Nasreen;
Bacha, Abir Ben;
Alonazi, Mona;
Albasher, Gadah;
Khayyat, Arwa Ishaq A.;
El-Ansary, Afaf

Publication type:

Article

Screening and Identification of the Rhizosphere Fungal Communities Associated with Land Reclamation in Egypt.

Published in:

Agriculture; Basel, 2023, v. 13, n. 1, p. 215, doi. 10.3390/agriculture13010215

By:

Nafaa, Mostafa;
Rizk, Samah Mohamed;
Aly, Tahany Abdel-Ghafar Ahmed;
Rashed, Mohamed Abdel-Salam;
Abd El-Moneim, Diaa;
Ben Bacha, Abir;
Alonazi, Mona;
Magdy, Mahmoud

Publication type:

Article

Comparative evaluation of certain biomarkers emphasizing abnormal GABA inhibitory effect and glutamate excitotoxicity in autism spectrum disorders.

Published in:

Frontiers in Psychiatry, 2025, p. 1, doi. 10.3389/fpsyt.2025.1562631

By:

Alabdali, Altaf;
Ben Bacha, Abir;
Alonazi, Mona;
Al-Ayadhi, Laila Y.;
Alanazi, Abdullah S. J.;
El‐Ansary, Afaf

Publication type:

Article

PRENATAL BEE POLLEN TREATMENT IMPROVES THE NEUROTOXICITY IN NEWBORN RATS DURING CHRONIC FLUORIDE EXPOSURE IN RELATION TO PROPIONIC ACID-INDUCED RODENT MODELS OF AUTISM.

Published in:

Fluoride, 2020, v. 53, n. 1, Part 1, p. 11

By:

Al-Daihan, Sooad;
Bacha, Abir Ben;
El-Ansary, Afaf;
Bhat, Ramesa Shafi

Publication type:

Article

Assessing the COX-2/PGE2 Ratio and Anti-Nucleosome Autoantibodies as Biomarkers of Autism Spectrum Disorders: Using Combined ROC Curves to Improve Diagnostic Values.

Published in:

Current Issues in Molecular Biology, 2024, v. 46, n. 8, p. 8699, doi. 10.3390/cimb46080513

By:

El-Ansary, Afaf;
Alfawaz, Hanan A.;
Ben Bacha, Abir;
AL-Ayadhi, Laila

Publication type:

Article

Therapeutic and Protective Potency of Bee Pollen Against Neurotoxic Effects Induced by Prenatal Exposure of Rats to Methyl Mercury.

Published in:

Journal of Molecular Neuroscience, 2018, v. 65, n. 3, p. 327, doi. 10.1007/s12031-018-1107-1

By:

Al-Osaimi, May;
El-Ansary, Afaf;
Al-Daihan, Sooad;
Bhat, Ramesa Shafi;
Ben Bacha, Abir

Publication type:

Article

Metabolism-Associated Markers and Childhood Autism Rating Scales (CARS) as a Measure of Autism Severity.

Published in:

Journal of Molecular Neuroscience, 2018, v. 65, n. 3, p. 265, doi. 10.1007/s12031-018-1091-5

By:

El-Ansary, Afaf;
Bjørklund, Geir;
Khemakhem, Asma M.;
Al-Ayadhi, Laila;
Chirumbolo, Salvatore;
Ben Bacha, Abir

Publication type:

Article

The therapeutic and protective effects of bee pollen against prenatal methylmercury induced neurotoxicity in rat pups.

Published in:

Metabolic Brain Disease, 2020, v. 35, n. 1, p. 215, doi. 10.1007/s11011-019-00496-z

By:

Ben Bacha, Abir;
Norah, Al-Orf;
Al-Osaimi, May;
Harrath, Abdel Halim;
Mansour, Lamjed;
El-Ansary, Afaf

Publication type:

Article

Correction to: Therapeutic effects of probiotics on neurotoxicity induced by clindamycin and propionic acid in juvenile hamsters.

Published in:

2018

By:

Al-Orf, Nora;
El-Ansary, Afaf;
Bjørklund, Geir;
Moubayed, Nadine;
Bhat, Ramesa Shafi;
Bacha, Abir Ben

Publication type:

Correction Notice

Therapeutic effects of probiotics on neurotoxicity induced by clindamycin and propionic acid in juvenile hamsters.

Published in:

Metabolic Brain Disease, 2018, v. 33, n. 6, p. 1811, doi. 10.1007/s11011-018-0284-5

By:

Al-Orf, Nora;
El-Ansary, Afaf;
Bjørklund, Geir;
Moubayed, Nadine;
Bhat, Ramesa Shafi;
Bacha, Abir Ben

Publication type:

Article

Probiotic treatment reduces the autistic-like excitation/inhibition imbalance in juvenile hamsters induced by orally administered propionic acid and clindamycin.

Published in:

Metabolic Brain Disease, 2018, v. 33, n. 4, p. 1155, doi. 10.1007/s11011-018-0212-8

By:

El-Ansary, Afaf;
Bacha, Abir Ben;
Bjørklund, Geir;
Al-Orf, Nora;
Bhat, Ramesa Shafi;
Moubayed, Nadine;
Abed, Kawther

Publication type:

Article

Secretory Phospholipase A in Dromedary Tears: a Host Defense Against Staphylococci and Other Gram-Positive Bacteria.

Published in:

Applied Biochemistry & Biotechnology, 2013, v. 169, n. 6, p. 1858, doi. 10.1007/s12010-013-0113-6

By:

Ben Bacha, Abir;
Abid, Islem

Publication type:

Article

Antibacterial Properties of Intestinal Phospholipase A from the Common Stingray Dasyatis pastinaca.

Published in:

Applied Biochemistry & Biotechnology, 2012, v. 168, n. 5, p. 1277, doi. 10.1007/s12010-012-9856-8

By:

Ben Bacha, Abir;
Abid, Islem;
Horchani, Habib

Publication type:

Article

Purification and Characterization of a Low Molecular Weight of β-Mannanase from Penicillium occitanis Pol6.

Published in:

Applied Biochemistry & Biotechnology, 2010, v. 160, n. 4, p. 1227, doi. 10.1007/s12010-009-8630-z

By:

Blibech, Monia;
Ghorbel, Raoudha Ellouz;
Fakhfakh, Ines;
Ntarima, Patricia;
Piens, Katheleen;
Bacha, Abir Ben;
Chaabouni, Semia Ellouz

Publication type:

Article

Urtica pilulifera leaves extract mitigates cadmium induced hepatotoxicity via modulation of antioxidants, inflammatory markers and Nrf-2 signaling in mice.

Published in:

Frontiers in Molecular Biosciences, 2024, p. 01, doi. 10.3389/fmolb.2024.1365440

By:

Hussein, Shaimaa;
Bacha, Abir Ben;
Alonazi, Mona;
Alwaili, Maha Abdullah;
Mobasher, Maysa A.;
Alburae, Najla Ali;
Banjabi, Abeer A.;
El-Said, Karim Samy

Publication type:

Article

Biochemical and Functional Characterization by Site-Directed Mutagenesis of a Phospholipase A 2 from Scorpio maurus Venom.

Published in:

Processes, 2023, v. 11, n. 12, p. 3364, doi. 10.3390/pr11123364

By:

Krayem, Najeh;
Alonazi, Mona;
Khemakhem, Bassem;
Horchani, Habib;
Cherif, Slim;
Karray, Aida;
Ben Bacha, Abir

Publication type:

Article

Novel Phospholipase C with High Catalytic Activity from a Bacillus stearothermophilus Strain: An Ideal Choice for the Oil Degumming Process.

Published in:

Processes, 2023, v. 11, n. 12, p. 3310, doi. 10.3390/pr11123310

By:

Alonazi, Mona;
Krayem, Najeh;
Alzahrani, Areej A.;
Horchani, Habib;
Ben Bacha, Abir

Publication type:

Article

Biochemical Study of Bacillus stearothermophilus Immobilized Lipase for Oily Wastewater Treatment.

Published in:

Processes, 2022, v. 10, n. 11, p. 2220, doi. 10.3390/pr10112220

By:

Ben Bacha, Abir;
Alonazi, Mona;
Alanazi, Humidah;
Alharbi, Mona G.;
Jallouli, Raida;
Karray, Aida

Publication type:

Article