Works matching AU Leitans, Janis

Results: 9

Surface Functionalization of ITO for Dual-Mode Hypoxia-Associated Cancer Biomarker Detection.

Published in:

Biosensors (2079-6374), 2025, v. 15, n. 3, p. 186, doi. 10.3390/bios15030186

By:

Zutis, Edmunds;
Paidere, Gunita;
Ruska, Rihards;
Freimanis, Toms;
Cipa, Janis;
Zalubovskis, Raivis;
Elksne, Maira;
Tars, Kaspars;
Kazaks, Andris;
Leitans, Janis;
Sarakovskis, Anatolijs;
Anspoks, Andris

Publication type:

Article

Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 130, doi. 10.3390/ijms23010130

By:

Zakšauskas, Audrius;
Čapkauskaitė, Edita;
Paketurytė-Latvė, Vaida;
Smirnov, Alexey;
Leitans, Janis;
Kazaks, Andris;
Dvinskis, Elviss;
Stančaitis, Laimonas;
Mickevičiūtė, Aurelija;
Jachno, Jelena;
Jezepčikas, Linas;
Linkuvienė, Vaida;
Sakalauskas, Andrius;
Manakova, Elena;
Gražulis, Saulius;
Matulienė, Jurgita;
Tars, Kaspars;
Matulis, Daumantas

Publication type:

Article

Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2621, doi. 10.3390/ijms21072621

By:

Hargunani, Priya;
Tadge, Nikhil;
Ceruso, Mariangela;
Leitans, Janis;
Kazaks, Andris;
Tars, Kaspars;
Gratteri, Paola;
Supuran, Claudiu T.;
Nocentini, Alessio;
Toraskar, Mrunmayee P.

Publication type:

Article

3 H -1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2017, v. 32, n. 1, p. 767, doi. 10.1080/14756366.2017.1316720

By:

Pustenko, Aleksandrs;
Stepanovs, Dmitrijs;
Žalubovskis, Raivis;
Vullo, Daniela;
Kazaks, Andris;
Leitans, Janis;
Tars, Kaspars;
Supuran, Claudiu T.

Publication type:

Article

Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.101401

By:

Vaškevičius, Aivaras;
Baronas, Denis;
Leitans, Janis;
Kvietkauskaitė, Agnė;
Rukšėnaitė, Audronė;
Manakova, Elena;
Toleikis, Zigmantas;
Kaupinis, Algirdas;
Kazaks, Andris;
Gedgaudas, Marius;
Mickevičiūtė, Aurelija;
Juozapaitienė, Vaida;
Schiöth, Helgi B.;
Jaudzems, Kristaps;
Valius, Mindaugas;
Tars, Kaspars;
Gražulis, Saulius;
Meyer-Almes, Franz-Josef;
Matulienė, Jurgita;
Zubrienė, Asta

Publication type:

Article

Front Cover: Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX (ChemMedChem 22/2023).

Published in:

ChemMedChem, 2023, v. 18, n. 22, p. 1, doi. 10.1002/cmdc.202300639

By:

Leitans, Janis;
Kazaks, Andris;
Bogans, Janis;
Supuran, Claudiu T.;
Akopjana, Inara;
Ivanova, Jekaterina;
Zalubovskis, Raivis;
Tars, Kaspars

Publication type:

Article

Structural Basis of Saccharin Derivative Inhibition of Carbonic Anhydrase IX.

Published in:

ChemMedChem, 2023, v. 18, n. 22, p. 1, doi. 10.1002/cmdc.202300454

By:

Leitans, Janis;
Kazaks, Andris;
Bogans, Janis;
Supuran, Claudiu T.;
Akopjana, Inara;
Ivanova, Jekaterina;
Zalubovskis, Raivis;
Tars, Kaspars

Publication type:

Article

Extending the Inhibition Profiles of Coumarin-Based Compounds Against Human Carbonic Anhydrases: Synthesis, Biological, and In Silico Evaluation.

Published in:

Molecules, 2019, v. 24, n. 19, p. 3580, doi. 10.3390/molecules24193580

By:

Kartsev, Victor;
Geronikaki, Athina;
Bua, Silvia;
Nocentini, Alessio;
Petrou, Anthi;
Lichitsky, Boris;
Frasinyuk, Mykhaylo;
Leitans, Janis;
Kazaks, Andris;
Tars, Kaspars;
Supuran, Claudiu T.

Publication type:

Article

Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 12, p. 1531, doi. 10.1107/S2053230X15022049

By:

Recacha, Rosario;
Leitans, Janis;
Akopjana, Inara;
Aprupe, Lilija;
Trapencieris, Peteris;
Jaudzems, Kristaps;
Jirgensons, Aigars;
Tars, Kaspars

Publication type:

Article