Works matching AU Cacciapuoti, Giovanna

Results: 33

A thermostable archaeal S -adenosylmethionine synthetase: a promising tool to improve the synthesis of adenosylmethionine analogs of biotechnological interest.

Published in:

Bioengineered, 2015, v. 6, n. 3, p. 184, doi. 10.1080/21655979.2015.1045170

By:

Porcelli, Marina;
Ilisso, Concetta Paola;
Mosca, Laura;
Cacciapuoti, Giovanna

Publication type:

Article

S-Adenosylmethionine Inhibits Colorectal Cancer Cell Migration through Mirna-Mediated Targeting of Notch Signaling Pathway †.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7673, doi. 10.3390/ijms23147673

By:

Borzacchiello, Luigi;
Veglia Tranchese, Roberta;
Grillo, Roberta;
Arpino, Roberta;
Mosca, Laura;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9286, doi. 10.3390/ijms22179286

By:

Mosca, Laura;
Pagano, Martina;
Borzacchiello, Luigi;
Mele, Luigi;
Russo, Annapina;
Russo, Giulia;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

S-Adenosylmethionine Inhibits Cell Growth and Migration of Triple Negative Breast Cancer Cells through Upregulating MiRNA-34c and MiRNA-449a.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 286, doi. 10.3390/ijms22010286

By:

Coppola, Alessandra;
Ilisso, Concetta Paola;
Stellavato, Antonietta;
Schiraldi, Chiara;
Caraglia, Michele;
Mosca, Laura;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 103, doi. 10.3390/ijms22010103

By:

Mosca, Laura;
Pagano, Martina;
Pecoraro, Annalisa;
Borzacchiello, Luigi;
Mele, Luigi;
Cacciapuoti, Giovanna;
Porcelli, Marina;
Russo, Giulia;
Russo, Annapina

Publication type:

Article

Therapeutic Potential of the Natural Compound S-Adenosylmethionine as a Chemoprotective Synergistic Agent in Breast, and Head and Neck Cancer Treatment: Current Status of Research.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8547, doi. 10.3390/ijms21228547

By:

Mosca, Laura;
Vitiello, Francesca;
Coppola, Alessandra;
Borzacchiello, Luigi;
Ilisso, Concetta Paola;
Pagano, Martina;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Protective Effect of Tyrosol and S-Adenosylmethionine against Ethanol-Induced Oxidative Stress of Hepg2 Cells Involves Sirtuin 1, P53 and Erk1/2 Signaling.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 5, p. 622, doi. 10.3390/ijms17050622

By:

Stiuso, Paola;
Bagarolo, Maria Libera;
Ilisso, Concetta Paola;
Vanacore, Daniela;
Martino, Elisa;
Caraglia, Michele;
Porcelli, Marina;
Cacciapuoti, Giovanna

Publication type:

Article

Biochemical Characterization of a Thermostable Adenosylmethionine Synthetase from the Archaeon Pyrococcus Furiosus with High Catalytic Power.

Published in:

Applied Biochemistry & Biotechnology, 2015, v. 175, n. 6, p. 2916, doi. 10.1007/s12010-015-1476-7

By:

Porcelli, Marina;
Ilisso, Concetta;
Leo, Ester;
Cacciapuoti, Giovanna

Publication type:

Article

Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49631-x

By:

Martino, Elisa;
Vuoso, Daniela Cristina;
D'Angelo, Stefania;
Mele, Luigi;
D'Onofrio, Nunzia;
Porcelli, Marina;
Cacciapuoti, Giovanna

Publication type:

Article

Purification and characterization of 5′-methylthioadenosine phosphorylase from the hyperthermophilic archaeon Pyrococcus furiosus: Substrate specificity and primary structure analysis.

Published in:

Extremophiles, 2003, v. 7, n. 2, p. 159, doi. 10.1007/s00792-002-0307-2

By:

Cacciapuoti, Giovanna;
Bertoldo, Costanzo;
Brio, Assunta;
Zappia, Vincenzo;
Porcelli, Marina

Publication type:

Article

Conformational changes and stabilization induced by phosphate binding to 5′-methylthioadenosine phosphorylase from the thermophilic archaeon Sulfolobus solfataricus.

Published in:

Extremophiles, 2001, v. 5, n. 5, p. 295, doi. 10.1007/s007920100205

By:

Cacciapuoti, Giovanna;
Servillo, Luigi;
Moretti, Maria;
Porcelli, Marina

Publication type:

Article

S-Adenosylmethionine, a Promising Antitumor Agent in Oral and Laryngeal Cancer.

Published in:

Applied Sciences (2076-3417), 2022, v. 12, n. 3, p. 1746, doi. 10.3390/app12031746

By:

Mosca, Laura;
Vitiello, Francesca;
Pagano, Martina;
Coppola, Alessandra;
Veglia Tranchese, Roberta;
Grillo, Roberta;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding.

Published in:

FEBS Journal, 2009, v. 276, n. 20, p. 5799, doi. 10.1111/j.1742-4658.2009.07247.x

By:

Cacciapuoti, Giovanna;
Peluso, Iolanda;
Fuccio, Francesca;
Porcelli, Marina

Publication type:

Article

Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus– biochemical characterization and homology modeling.

Published in:

FEBS Journal, 2008, v. 275, n. 8, p. 1900, doi. 10.1111/j.1742-4658.2008.06348.x

By:

Porcelli, Marina;
Concilio, Luigi;
Peluso, Iolanda;
Marabotti, Anna;
Facchiano, Angelo;
Cacciapuoti, Giovanna

Publication type:

Article

Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.

Published in:

FEBS Journal, 2007, v. 274, n. 10, p. 2482, doi. 10.1111/j.1742-4658.2007.05784.x

By:

Cacciapuoti, Giovanna;
Gorassini, Sabrina;
Mazzeo, Maria Fiorella;
Siciliano, Rosa Anna;
Carbone, Virginia;
Zappia, Vincenzo;
Porcelli, Marina

Publication type:

Article

A novel hyperthermostable 5′-deoxy-5′-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus.

Published in:

FEBS Journal, 2005, v. 272, n. 8, p. 1886, doi. 10.1111/j.1742-4658.2005.04619.x

By:

Cacciapuoti, Giovanna;
Forte, Sabrina;
Moretti, Maria Angela;
Brio, Assunta;
Zappia, Vincenzo;
Porcelli, Marina

Publication type:

Article

Mutual Correlation between Non-Coding RNA and S-Adenosylmethionine in Human Cancer: Roles and Therapeutic Opportunities.

Published in:

Cancers, 2021, v. 13, n. 13, p. 3264, doi. 10.3390/cancers13133264

By:

Mosca, Laura;
Vitiello, Francesca;
Borzacchiello, Luigi;
Coppola, Alessandra;
Tranchese, Roberta Veglia;
Pagano, Martina;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Mi-RNA-888-5p Is Involved in S-Adenosylmethionine Antitumor Effects in Laryngeal Squamous Cancer Cells.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3665, doi. 10.3390/cancers12123665

By:

Pagano, Martina;
Mosca, Laura;
Vitiello, Francesca;
Ilisso, Concetta Paola;
Coppola, Alessandra;
Borzacchiello, Luigi;
Mele, Luigi;
Caruso, Francesca Pia;
Ceccarelli, Michele;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Homocysteine-induced endothelial cell adhesion is related to adenosine lowering and is not mediated by S-adenosylhomocysteine

Published in:

FEBS Letters, 2007, v. 581, n. 24, p. 4567, doi. 10.1016/j.febslet.2007.08.042

By:

Cacciapuoti, Giovanna;
Manna, Caterina;
Napoli, Daniela;
Zappia, Vincenzo;
Porcelli, Marina

Publication type:

Article

S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: Biochemical characterization and analysis of protein structure by comparative molecular modeling.

Published in:

Proteins, 2005, v. 58, n. 4, p. 815, doi. 10.1002/prot.20381

By:

Porcelli, Marina;
Moretti, Maria Angela;
Concilio, Luigi;
Forte, Sabrina;
Merlino, Antonello;
Graziano, Giuseppe;
Cacciapuoti, Giovanna

Publication type:

Article

Annurca apple polyphenol extract promotes mesenchymal-to-epithelial transition and inhibits migration in triple-negative breast cancer cells through ROS/JNK signaling.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73092-2

By:

Vuoso, Daniela Cristina;
D'Angelo, Stefania;
Ferraro, Rosalia;
Caserta, Sergio;
Guido, Stefano;
Cammarota, Marcella;
Porcelli, Marina;
Cacciapuoti, Giovanna

Publication type:

Article

Site-directed mutagenesis gives insights into substrate specificity of Sulfolobus solfataricus purine-specific nucleoside hydrolase.

Published in:

Annals of Microbiology, 2012, v. 62, n. 2, p. 881, doi. 10.1007/s13213-011-0379-2

By:

Porcelli, Marina;
Leo, Ester;
Marabotti, Anna;
Cacciapuoti, Giovanna

Publication type:

Article

Effects of S-adenosyl-L-methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms.

Published in:

International Journal of Oncology, 2020, v. 56, n. 5, p. 1212, doi. 10.3892/ijo.2020.5011

By:

Mosca, Laura;
Minopoli, Michele;
Pagano, Martina;
Vitiello, Francesca;
Carriero, Maria Vincenza;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

Pro-oxidant and pro-apoptotic activity of polyphenol extract from Annurca apple and its underlying mechanisms in human breast cancer cells.

Published in:

International Journal of Oncology, 2017, v. 51, n. 3, p. 939, doi. 10.3892/ijo.2017.4088

By:

D'ANGELO, STEFANIA;
MARTINO, ELISA;
PAOLAILISSO, CONCETTA;
BAGAROLO, MARIA LIBERA;
PORCELLI, MARINA;
CACCIAPUOTI, GIOVANNA

Publication type:

Article

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs.

Published in:

Cancer Cell International, 2018, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12935-018-0697-6

By:

Ilisso, Concetta Paola;
Delle Cave, Donatella;
Mosca, Laura;
Pagano, Martina;
Coppola, Alessandra;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina;
Mele, Luigi

Publication type:

Article

Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP.

Published in:

Journal of Cellular Biochemistry, 2016, v. 117, n. 5, p. 1126, doi. 10.1002/jcb.25396

By:

Cacciapuoti, Giovanna;
Bagarolo, Maria Libera;
Martino, Elisa;
Scafuri, Bernardina;
Marabotti, Anna;
Porcelli, Marina

Publication type:

Article

Antitumoral Activity of the Universal Methyl Donor S -Adenosylmethionine in Glioblastoma Cells.

Published in:

Molecules, 2024, v. 29, n. 8, p. 1708, doi. 10.3390/molecules29081708

By:

Mosca, Laura;
Pagano, Cristina;
Tranchese, Roberta Veglia;
Grillo, Roberta;
Cadoni, Francesca;
Navarra, Giovanna;
Coppola, Laura;
Pagano, Martina;
Mele, Luigi;
Cacciapuoti, Giovanna;
Laezza, Chiara;
Porcelli, Marina

Publication type:

Article

Polyphenol Extract from "Greco" Grape Canes: Characterization, Antioxidant Capacity, and Antitumor Effects on Cal-33 and JHU-SCC-011 Head and Neck Squamous Cell Carcinoma.

Published in:

Molecules, 2022, v. 27, n. 8, p. N.PAG, doi. 10.3390/molecules27082576

By:

Squillaci, Giuseppe;
Vitiello, Francesca;
Mosca, Laura;
La Cara, Francesco;
Cacciapuoti, Giovanna;
Porcelli, Marina;
Morana, Alessandra

Publication type:

Article

Erratum to: The methyl donor S-adenosylmethionine potentiates doxorubicin effects on apoptosis of hormone-dependent breast cancer cell lines.

Published in:

2016

By:

Ilisso, Concetta;
Castellano, Maria;
Zappavigna, Silvia;
Lombardi, Angela;
Vitale, Giovanni;
Dicitore, Alessandra;
Cacciapuoti, Giovanna;
Caraglia, Michele;
Porcelli, Marina

Publication type:

Erratum

The methyl donor S-adenosylmethionine potentiates doxorubicin effects on apoptosis of hormone-dependent breast cancer cell lines.

Published in:

Endocrine (1355008X), 2015, v. 50, n. 1, p. 212, doi. 10.1007/s12020-014-0484-7

By:

Ilisso, Concetta;
Castellano, Maria;
Zappavigna, Silvia;
Lombardi, Angela;
Vitale, Giovanni;
Dicitore, Alessandra;
Cacciapuoti, Giovanna;
Caraglia, Michele;
Porcelli, Marina

Publication type:

Article

AdoMet triggers apoptosis in head and neck squamous cancer by inducing ER stress and potentiates cell sensitivity to cisplatin.

Published in:

Journal of Cellular Physiology, 2019, v. 234, n. 8, p. 13277, doi. 10.1002/jcp.28000

By:

Mosca, Laura;
Pagano, Martina;
Ilisso, Concetta Paola;
Cave, Donatella Delle;
Desiderio, Vincenzo;
Mele, Luigi;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

S-Adenosylmethionine-mediated apoptosis is potentiated by autophagy inhibition induced by chloroquine in human breast cancer cells.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 2, p. 1370, doi. 10.1002/jcp.26015

By:

Cave, Donatella Delle;
Desiderio, Vincenzo;
Mosca, Laura;
Ilisso, Concetta P.;
Mele, Luigi;
Caraglia, Michele;
Cacciapuoti, Giovanna;
Porcelli, Marina

Publication type:

Article

S-Adenosylmethionine Affects ERK1/2 and Stat3 Pathways and Induces Apotosis in Osteosarcoma Cells.

Published in:

Journal of Cellular Physiology, 2016, v. 231, n. 2, p. 428, doi. 10.1002/jcp.25089

By:

Ilisso, Concetta Paola;
Sapio, Luigi;
Delle Cave, Donatella;
Illiano, Michela;
Spina, Annamaria;
Cacciapuoti, Giovanna;
Naviglio, Silvio;
Porcelli, Marina

Publication type:

Article