Works matching Tabun
Results: 280
Theoretical study on the aging and reactivation mechanism of tabun-inhibited acetylcholinesterase by using the quantum mechanical / molecular mechanical method.
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- Canadian Journal of Chemistry, 2012, v. 90, n. 4, p. 376, doi. 10.1139/v2012-007
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Changes of rat plasma total low molecular weight antioxidant level after tabun exposure and consequent treatment by acetylcholinesterase reactivators.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2011, v. 26, n. 1, p. 93, doi. 10.3109/14756361003733613
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A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 6, p. 790, doi. 10.3109/14756360903433373
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In vivo experimental approach to treatment against tabun poisoning.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 531, doi. 10.3109/14756360903357593
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A comparison of reactivating and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 480, doi. 10.3109/14756360903257918
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A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 4, p. 1040, doi. 10.1080/14756360802608419
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Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 4, p. 425, doi. 10.1080/14756360601164960
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A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 3, p. 297, doi. 10.1080/14756360601114361
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Probing O-dealkylation and deamination aging processes in tabun-conjugated AChE: a computational study.
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- Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2012, v. 131, n. 3, p. 1, doi. 10.1007/s00214-012-1175-1
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Mass Spectrometry Method to Identify Aging Pathways of Sp- and Rp-Tabun Adducts on Human Butyrylcholinesterase Based on the Acid Labile P-N Bond.
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- Toxicological Sciences, 2013, v. 132, n. 2, p. 390, doi. 10.1093/toxsci/kft011
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In vitro Reactivation Potency of Acetylcholinesterase Reactivators -- K074 and K075 -- to Reactivate Tabun-inhibited Human Brain Cholinesterases.
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- Neurotoxicity Research, 2007, v. 11, n. 2, p. 101, doi. 10.1007/BF03033389
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The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice.
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- Journal of Applied Toxicology, 2010, v. 30, n. 2, p. 120, doi. 10.1002/jat.1477
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In vivo protection studies of bis-quaternary 2-(hydroxyimino)- N-(pyridin-3-yl) acetamide derivatives (HNK oximes) against tabun and soman poisoning in Swiss albino mice.
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- Human & Experimental Toxicology, 2017, v. 36, n. 12, p. 1270, doi. 10.1177/0960327116685888
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A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K305, K307) with the oxime K203 and trimedoxime in tabun-poisoned rats and mice.
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- Journal of Applied Biomedicine, 2017, v. 15, n. 1, p. 49, doi. 10.1016/j.jab.2016.09.008
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A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K920, K923) with the oxime K203 and trimedoxime in tabun-poisoned rats and mice.
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- Journal of Applied Biomedicine, 2015, v. 13, n. 4, p. 299, doi. 10.1016/j.jab.2015.07.002
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The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats--A Comparison with Trimedoxime and the Oxime K203.
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- Molecules, 2017, v. 22, n. 7, p. 1152, doi. 10.3390/molecules22071152
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A comparison of the reactivating and therapeutic efficacy of newly developed oximes (K347, K628) with commonly used oximes (obidoxime, HI-6) against tabun in rats and mice.
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- Drug & Chemical Toxicology, 2010, v. 33, n. 3, p. 227, doi. 10.3109/01480540903483409
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A Comparison of neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats.
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- Drug & Chemical Toxicology, 2009, v. 32, n. 2, p. 128, doi. 10.1080/01480540802593873
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A Comparison of the Therapeutic and Reactivating Efficacy of Newly Developed Oximes (K117, K127) and Currently Available Oximes (Obidoxime, Trimedoxime, HI-6) in Tabun-Poisoned Rats and Mice.
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- Drug & Chemical Toxicology, 2008, v. 31, n. 3, p. 371, doi. 10.1080/01480540802171258
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A Comparison of the Potency of Newly Developed Oximes (K074, K075) and Currently Available Oximes (Obidoxime, Trimedoxime, Hi-6) to Counteract Acute Toxic Effects of Tabun and Cyclosarin in Mice.
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- Drug & Chemical Toxicology, 2008, v. 31, n. 1, p. 127, doi. 10.1080/01480540701688816
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PROTECTIVE EFFECT OF HI-6 AND TRIMEDOXIME COMBINATION IN MICE ACUTELY POISONED WITH TABUN, DICHLORVOS OR HEPTENOPHOS.
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- Acta Veterinaria, 2012, v. 62, n. 2/3, p. 123, doi. 10.2298/AVB1203123A
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Neuroprotective efficacy of newly developed oximes in comparison with currently available oximes in tabun-poisoned rats.
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- Journal of Applied Biomedicine, 2015, v. 13, n. 1, p. 39, doi. 10.1016/j.jab.2014.10.001
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Evaluation of the neuroprotective efficacy of individual oxime (HI-6) and oxime mixtures (HI-6 + trimedoxime, HI-6 + K203) in tabun-poisoned rats.
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- Journal of Applied Biomedicine, 2009, v. 7, n. 4, p. 189, doi. 10.32725/jab.2009.021
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Effects of Oxime K203 and Oxidative Stress in Plasma of Tabun Poisoned Rats.
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- Croatica Chemica Acta, 2012, v. 85, n. 2, p. 193, doi. 10.5562/cca1811
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Chapter 17: Investigation of the Efficacy of New Reactivators of Cholinesterase in Soman and Tabun Inhibited Rat Brain Acetylcholinesterase.
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- Journal of Medical Chemical, Biological & Radiological Defense, 2010, v. 8, p. 121
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A Method for the Analysis of Tabun in Multisol Using Gas Chromatographic Flame Photometric Detection.
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- Toxicology Mechanisms & Methods, 2006, v. 16, n. 7, p. 359, doi. 10.1080/15376520600620083
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Reactivation of Immobilized Acetylcholinesterase-Tabun Complex by Methoxime and Its Homologues.
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- Drug & Chemical Toxicology, 2007, v. 30, n. 2, p. 97, doi. 10.1080/01480540601186614
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In Vitro Evaluation of Acetylcholinesterase Reactivators as Potential Antidotes Against Tabun Nerve Agent Poisonings.
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- Drug & Chemical Toxicology, 2006, v. 29, n. 4, p. 443, doi. 10.1080/01480540600718565
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Chapter 13: Biological Markers of Intoxication with Nerve Agents - Biochemical investigations in rats poisoned with tabun.
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- Journal of Medical Chemical, Biological & Radiological Defense, 2010, v. 8, p. 94
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Oxime K203: a drug candidate for the treatment of tabun intoxication.
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- Archives of Toxicology, 2019, v. 93, n. 3, p. 673, doi. 10.1007/s00204-018-2377-7
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A comparison of the potency of newly developed oximes (K027, K048) and commonly used oximes (obidoxime, HI-6) to counteract tabun-induced neurotoxicity in rats.
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- Journal of Applied Toxicology, 2006, v. 26, n. 4, p. 309, doi. 10.1002/jat.1137
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Effective bisquaternary reactivators of tabun‐inhibited AChE.
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- Journal of Applied Toxicology, 2005, v. 25, n. 6, p. 491, doi. 10.1002/jat.1084
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Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes.
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- Clinical Pharmacology & Therapeutics, 2007, v. 82, n. 3, p. 282, doi. 10.1038/sj.clpt.6100151
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The Evaluation of the Neuroprotective Effects of Bispyridinium Oximes in Tabun-Poisoned Rats.
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- Journal of Toxicology & Environmental Health: Part A, 2007, v. 70, n. 18, p. 1556, doi. 10.1080/15287390701384775
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A Comparison of the Efficacy of New Asymmetric Bispyridinium Oximes (K027, K048) with Currently Available Oximes Against Tabun by In Vivo Methods.
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- Journal of Toxicology & Environmental Health: Part A, 2006, v. 69, n. 20, p. 1875, doi. 10.1080/15287390600631730
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ENHANCEMENT IN PYRIDINIUM OXIME-ASSISTED REACTIVATION OF TABUN-INHIBITED ACETYLCHOLINESTERASE ACHIEVED BY ACTIVE SITE MUTATIONS.
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- Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 14
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Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase.
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- Chemistry - A European Journal, 2019, v. 25, n. 16, p. 4100, doi. 10.1002/chem.201805051
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Toxicity of the nerve agent tabun to Daphnia magna , a new experimental species in military toxicology.
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- Chemistry & Ecology, 2006, v. 22, n. 2, p. 175, doi. 10.1080/02757540600579383
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Evaluation of the Potency of Two Novel Bispyridinium Oximes ( K456, K458) in Comparison with Oxime K203 and Trimedoxime to Counteract Tabun-Induced Neurotoxicity in Rats.
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- Basic & Clinical Pharmacology & Toxicology, 2013, v. 113, n. 3, p. 201, doi. 10.1111/bcpt.12083
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Delayed Neurological Complications of Sulphur Mustard and Tabun Poisoning in 43 Iranian Veterans.
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- Basic & Clinical Pharmacology & Toxicology, 2012, v. 111, n. 6, p. 426, doi. 10.1111/j.1742-7843.2012.00922.x
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A Comparison of Neuroprotective Efficacy of the Oxime K203 and its Fluorinated Analogue (KR-22836) with Obidoxime in Tabun-Poisoned Rats.
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- Basic & Clinical Pharmacology & Toxicology, 2010, v. 107, n. 5, p. 861, doi. 10.1111/j.1742-7843.2010.00588.x
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Bisquaternary Oximes as Reactivators of Tabun-Inhibited Human Brain Cholinesterases: An in vitro Study.
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- Basic & Clinical Pharmacology & Toxicology, 2007, v. 101, n. 1, p. 25, doi. 10.1111/j.1742-7843.2007.00085.x
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Specification of the Structure of Oximes Able to Reactivate Tabun-Inhibited Acetylcholinesterase.
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- Basic & Clinical Pharmacology & Toxicology, 2004, v. 95, n. 2, p. 81, doi. 10.1111/j.1742-7843.2004.950207.x
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Reactivation of Tabun-inhibited Acetylcholinesterase Investigated by Two Oximes and Mutagenesis.
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- Croatica Chemica Acta, 2012, v. 85, n. 2, p. 209, doi. 10.5562/cca1815
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- Article
A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase.
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- BMC Pharmacology & Toxicology, 2018, v. 19, p. 1, doi. 10.1186/s40360-018-0196-3
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In Silico Studies in Probing the Role of Kinetic and Structural Effects of Different Drugs for the Reactivation of Tabun-Inhibited AChE.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0079591
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Energetics of Ortho-7 (Oxime Drug) Translocation through the Active-Site Gorge of Tabun Conjugated Acetylcholinesterase.
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- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040188
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A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant).
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- Materials (1996-1944), 2019, v. 12, n. 18, p. 2943, doi. 10.3390/ma12182943
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Reactivation of Human Brain Homogenate Cholinesterases Inhibited by Tabun using Newly Developed Oximes K117 and K127.
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- Basic & Clinical Pharmacology & Toxicology, 2009, v. 105, n. 3, p. 207, doi. 10.1111/j.1742-7843.2009.00421.x
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Frontispiece: A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials.
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- Chemistry - A European Journal, 2016, v. 22, n. 32, p. n/a, doi. 10.1002/chem.201683261
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