Works matching THC receptors

Results: 132

CB1 Receptor Antagonist Selonabant (ANEB‐001) Blocks Acute THC Effects in Healthy Volunteers: A Phase II Randomized Controlled Trial.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 5, p. 1427, doi. 10.1002/cpt.3581

By:

Gorbenko, Andriy A.;
Heuberger, Jules A. A. C.;
Juachon, Maria;
Klaassen, Erica;
Tagen, Michael;
Lawler, Joseph F.;
Schneeberger, Daniel;
Cundy, Kenneth C.;
Klumpers, Linda E.;
Groeneveld, Geert J.

Publication type:

Article

Selective Reduction of THC’s Unwanted Effects through Serotonin Receptor Inhibition.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002193

By:

Robinson, Richard

Publication type:

Article

Cannabidiol Exerts Anticonvulsant Effects Alone and in Combination with Δ 9 -THC through the 5-HT1A Receptor in the Neocortex of Mice.

Published in:

Cells (2073-4409), 2024, v. 13, n. 6, p. 466, doi. 10.3390/cells13060466

By:

Javadzadeh, Yasaman;
Santos, Alexandra;
Aquilino, Mark S.;
Mylvaganam, Shanthini;
Urban, Karolina;
Carlen, Peter L.

Publication type:

Article

Potential Pro-Inflammatory Effect of Vitamin E Analogs through Mitigation of Tetrahydrocannabinol (THC) Binding to the Cannabinoid 2 Receptor.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 8, p. 4291, doi. 10.3390/ijms23084291

By:

Manandhar, Anjela;
Haron, Mona H.;
Ross, Samir A.;
Klein, Michael L.;
Elokely, Khaled M.

Publication type:

Article

Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade on Δ9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 19, p. 6480, doi. 10.1523/JNEUROSCI.5073-13.2014

By:

Justinova, Zuzaná;
Redhi, Godfrey H.;
Goldberg, Steven R.;
Ferré, Sergi

Publication type:

Article

The Cannabinoid Receptor Agonist THC Attenuates Weight Loss in a Rodent Model of Activity-Based Anorexia.

Published in:

Neuropsychopharmacology, 2011, v. 36, n. 7, p. 1349, doi. 10.1038/npp.2011.19

By:

Verty, Aaron N. A.;
Evetts, Megan J.;
Crouch, Geraldine J.;
McGregor, Iain S.;
Stefanidis, Aneta;
Oldfield, Brian J.

Publication type:

Article

The cannabinoid CB receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice.

Published in:

Psychopharmacology, 2013, v. 229, n. 4, p. 591, doi. 10.1007/s00213-013-3117-6

By:

Ignatowska-Jankowska, Bogna;
Muldoon, Pretal;
Lichtman, Aron;
Damaj, M.

Publication type:

Article

Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond.

Published in:

Addiction Biology, 2008, v. 13, n. 2, p. 147, doi. 10.1111/j.1369-1600.2008.00108.x

By:

Pertwee, Roger G.

Publication type:

Article

A PCR marker Linked to a THCA synthase Polymorphism is a Reliable Tool to Discriminate Potentially THC-Rich Plants of Cannabis sativa L.

Published in:

Journal of Forensic Sciences, 2014, v. 59, n. 4, p. 919, doi. 10.1111/1556-4029.12448

By:

Staginnus, Christina;
Zörntlein, Siegfried;
Meijer, Etienne

Publication type:

Article

Neuronal nicotinic acetylcholine receptors mediate ∆9 -THC dependence: Mouse and human studies.

Published in:

2020

By:

Donvito, Giulia;
Muldoon, Pretal P.;
Jackson, Kia J.;
Ahmad, Urslan;
Zaveri, Nur T.;
McIntosh, J. Michael;
Chen, Xiangning;
Lichtman, Aron H.;
Damaj, M. Imad

Publication type:

journal article

CB1 and CB2 Cannabinoid Receptors Mediate Different Aspects of Delta-9-Tetrahydrocannabinol (THC)-Induced T Helper Cell Shift Following Immune Activation by Legionella Pneumophila Infection.

Published in:

Journal of NeuroImmune Pharmacology, 2009, v. 4, n. 4, p. 92, doi. 10.1007/s11481-008-9126-2

By:

Newton, Catherine;
Chou, Ping-Jen;
Perkins, Izabella;
Klein, Thomas

Publication type:

Article

CB1 and CB2 Cannabinoid Receptors Mediate Different Aspects of Delta-9-Tetrahydrocannabinol (THC)-Induced T Helper Cell Shift Following Immune Activation by Legionella Pneumophila Infection.

Published in:

Journal of NeuroImmune Pharmacology, 2009, v. 4, n. 1, p. 92, doi. 10.1007/s11481-008-9126-2

By:

Newton, Catherine;
Chou, Ping-Jen;
Perkins, Izabella;
Klein, Thomas

Publication type:

Article

The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons.

Published in:

PLoS Biology, 2015, v. 13, n. 10, p. 1, doi. 10.1371/journal.pbio.1002286

By:

Njoo, Christian;
Agarwal, Nitin;
Lutz, Beat;
Kuner, Rohini

Publication type:

Article

Kanabidiol, kanabinoidy a jejich vliv na celkovou anestezii.

Published in:

Remedia, 2024, v. 34, n. 6, p. 480

By:

Hess, Ladislav

Publication type:

Article

Down-regulation of the AMPA glutamate receptor subunits GluR1 and GluR2/3 in the rat cerebellum following pre- and perinatal Δ9-tetrahydrocannabinol exposure.

Published in:

Cerebellum, 2004, v. 3, n. 2, p. 66

By:

Suárez, Isabel;
Bodega, Guillermo;
Fermández-Ruitz, Javier;
Ramos, José Antonio;
Rubio, Miguel;
Fernandez, Benjamín

Publication type:

Article

The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

Published in:

2005

By:

O'Sullivan, Saoirse E;
Kendall, David A;
Randall, Michael D

Publication type:

journal article

The effects of Δ9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

Published in:

British Journal of Pharmacology, 2005, v. 145, n. 4, p. 514, doi. 10.1038/sj.bjp.0706218

By:

O'Sullivan, Saoirse E.;
Kendall, David A.;
Randall, Michael D.

Publication type:

Article

Emergence of Synthetic Cannabinoids as Drugs of Abuse.

Published in:

Indian Journal of Forensic Medicine & Toxicology, 2022, v. 16, n. 1, p. 89, doi. 10.37506/ijfmt.v16i1.17422

By:

Joshi, Nupur;
Sankhla, Mahipal Singh

Publication type:

Article

The pharmacokinetics of THC in fat and brain: resulting functional responses to marihuana smoking.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2001, v. 16, n. 3, p. 247, doi. 10.1002/hup.258

By:

Nahas, Gabriel G.

Publication type:

Article

Psychoactive cannabinoids and membrane signaling.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2000, v. 15, n. 7, p. 535, doi. 10.1002/1099-1077(200010)15:7<535::AID-HUP229>3.0.CO;2-7

By:

Nahas, Gabriel G.;
Harvey, David J.;
Sutin, Kenneth M.

Publication type:

Article

Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes.

Published in:

Journal of Biosciences, 2008, v. 33, n. 1, p. 63, doi. 10.1007/s12038-008-0022-y

By:

Murugan, Pidaran;
Pari, Leelavinothan;
Rao, Chippada Appa

Publication type:

Article

Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2006, v. 372, n. 5, p. 354, doi. 10.1007/s00210-006-0033-x

By:

Kathmann, Markus;
Flau, Karsten;
Redmer, Agnes;
Tränkle, Christian;
Schlicker, Eberhard

Publication type:

Article

Administration of Δ9‐Tetrahydrocannabinol (THC) Post‐Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00893

By:

Mohammed, Amira;
Alghetaa, Hasan;
Sultan, Muthanna;
Singh, Narendra P.;
Nagarkatti, Prakash;
Nagarkatti, Mitzi

Publication type:

Article

A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34921-2

By:

Watari, Hiromi;
Kageyama, Hiromu;
Masubuchi, Nami;
Nakajima, Hiroya;
Onodera, Kako;
Focia, Pamela J.;
Oshiro, Takumi;
Matsui, Takashi;
Kodera, Yoshio;
Ogawa, Tomohisa;
Yokoyama, Takeshi;
Hirayama, Makoto;
Hori, Kanji;
Freymann, Douglas M.;
Imai, Misa;
Komatsu, Norio;
Araki, Marito;
Tanaka, Yoshikazu;
Sakai, Ryuichi

Publication type:

Article

Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors.

Published in:

Allergy, 2013, v. 68, n. 8, p. 994, doi. 10.1111/all.12183

By:

Gaffal, E.;
Cron, M.;
Glodde, N.;
Tüting, T.

Publication type:

Article

FAAH−/− Mice Display Differential Tolerance, Dependence, and Cannabinoid Receptor Adaptation After Δ9-Tetrahydrocannabinol and Anandamide Administration.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 8, p. 1775, doi. 10.1038/npp.2010.44

By:

Falenski, Katherine W.;
Thorpe, Andrew J.;
Schlosburg, Joel E.;
Cravatt, Benjamin F.;
Abdullah, Rehab A.;
Smith, Tricia H.;
Selley, Dana E.;
Lichtman, Aron H.;
Sim-Selley, Laura J.

Publication type:

Article

Role of vasopressin V1a receptor in ∆-tetrahydrocannabinol-induced cataleptic immobilization in mice.

Published in:

Psychopharmacology, 2017, v. 234, n. 23/24, p. 3475, doi. 10.1007/s00213-017-4735-1

By:

Egashira, Nobuaki;
Koushi, Emi;
Myose, Takayuki;
Tanoue, Akito;
Mishima, Kenichi;
Tsuchihashi, Ryota;
Kinjo, Junei;
Tanaka, Hiroyuki;
Morimoto, Satoshi;
Iwasaki, Katsunori

Publication type:

Article

Tetrahydrocannabinol and dopamine D1 receptor.

Published in:

Frontiers in Neuroscience, 2024, p. 1, doi. 10.3389/fnins.2024.1360205

By:

Lee, Jiwon

Publication type:

Article

Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ9-tetrahydrocannabinol.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90902-3

By:

Kanyo, Richard;
Amin, Md Ruhul;
Locskai, Laszlo F.;
Bouvier, Danika D.;
Olthuis, Alexandria M.;
Allison, W. Ted;
Ali, Declan W.

Publication type:

Article

Motivational Effects of Cannabinoids and Opioids on Food Reinforcement Depend on Simultaneous Activation of Cannabinoid and Opioid Systems.

Published in:

Neuropsychopharmacology, 2005, v. 30, n. 11, p. 2035, doi. 10.1038/sj.npp.1300720

By:

Solinas, Marcello;
Goldberg, Steven R

Publication type:

Article

THC-induced behavioral stereotypy in zebrafish as a model of psychosis-like behavior.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95016-4

By:

Dahlén, Amelia;
Zarei, Mahdi;
Melgoza, Adam;
Wagle, Mahendra;
Guo, Su

Publication type:

Article

Suppression of STAT3 Signaling by Δ9-Tetrahydrocannabinol (THC) Induces Trophoblast Dysfunction.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 42, n. 2, p. 537, doi. 10.1159/000477603

By:

Chang, Xinwen;
Bian, Yiding;
He, Qizhi;
Yao, Julei;
Zhu, Jingping;
Wu, Jinting;
Wang, Kai;
Duan, Tao

Publication type:

Article

Involvement of opioid system in cognitive deficits induced by ∆-tetrahydrocannabinol in rats.

Published in:

Psychopharmacology, 2012, v. 219, n. 4, p. 1111, doi. 10.1007/s00213-011-2442-x

By:

Egashira, Nobuaki;
Manome, Naomi;
Mishima, Kenichi;
Iwasaki, Katsunori;
Oishi, Ryozo;
Fujiwara, Michihiro

Publication type:

Article

Cannabidiol potentiates Δ-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

Published in:

Psychopharmacology, 2011, v. 218, n. 2, p. 443, doi. 10.1007/s00213-011-2342-0

By:

Klein, Charlotte;
Karanges, Emily;
Spiro, Adena;
Wong, Alexander;
Spencer, Jarrah;
Huynh, Thanh;
Gunasekaran, Nathan;
Karl, Tim;
Long, Leonora;
Huang, Xu-Feng;
Liu, Kelly;
Arnold, Jonathon;
McGregor, Iain

Publication type:

Article

Interactions between Δ9-tetrahydrocannabinol and μ opioid receptor agonists in rhesus monkeys: discrimination and antinociception.

Published in:

Psychopharmacology, 2008, v. 199, n. 2, p. 199, doi. 10.1007/s00213-008-1157-0

By:

Li, Jun-Xu;
McMahon, Lance;
Gerak, Lisa;
Becker, Ginger;
France, Charles

Publication type:

Article

The effects of cannabidiol and its main metabolites on human neural stem cells.

Published in:

Experimental Biology & Medicine, 2025, p. 1, doi. 10.3389/ebm.2025.10608

By:

Latham, Leah E.;
Gu, Qiang;
Liu, Shuliang;
Wang, Cheng;
Liu, Fang

Publication type:

Article

Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002194

By:

Viñals, Xavier;
Moreno, Estefanía;
Lanfumey, Laurence;
Cordomí, Arnau;
Pastor, Antoni;
de La Torre, Rafael;
Gasperini, Paola;
Navarro, Gemma;
Howell, Lesley A.;
Pardo, Leonardo;
Lluís, Carmen;
Canela, Enric I.;
McCormick, Peter J.;
Maldonado, Rafael;
Robledo, Patricia

Publication type:

Article

Nabilone shows promise for agitation in patients with Alzheimer's disease.

Published in:: Brown University Psychopharmacology Update, 2019, v. 30, n. 10, p. 7, doi. 10.1002/pu.30485
Publication type:: Article

Investigation the effects of synthetic cannabinoid-AKB48 on DNA methylation via the regulation of cannabinoid receptor gene specific methylation in vitro.

Published in:

Journal of Research in Pharmacy, 2021, v. 25, n. 5, p. 626, doi. 10.29228/jrp.54

By:

KARAMAN, Ecem Fatma;
YİĞİTER, Şemsinur;
ÖZDEN, Sibel

Publication type:

Article

Cannabis and cancer: unveiling the potential of a green ally in breast, colorectal, and prostate cancer.

Published in:

Journal of Cannabis Research, 2024, v. 6, n. 1, p. 1, doi. 10.1186/s42238-024-00233-z

By:

ALSalamat, Husam A.;
Abuarab, Sara Feras;
Salamah, Hazem Mohamed;
Ishqair, Anas Hasan;
Dwikat, Mohammad Fuad;
Nourelden, Anas Zakarya;
Qandil, Aseel N.;
Barakat, Yasmeen;
Barakat, Muna

Publication type:

Article

Delta-9-Tetrahydrocannabinol Blocks Bone Marrow-Derived Macrophage Differentiation through Elimination of Reactive Oxygen Species.

Published in:

Antioxidants, 2024, v. 13, n. 8, p. 887, doi. 10.3390/antiox13080887

By:

Carter, Taylor H.;
Weyer-Nichols, Chloe E.;
Garcia-Sanchez, Jeffrey I.;
Wilson, Kiesha;
Nagarkatti, Prakash;
Nagarkatti, Mitzi

Publication type:

Article

Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2013, v. 38, n. 2, p. 162, doi. 10.1111/jcpt.12018

By:

Crippa, J. A. S.;
Hallak, J. E. C.;
Machado‐de‐Sousa, J. P.;
Queiroz, R. H. C.;
Bergamaschi, M.;
Chagas, M. H. N.;
Zuardi, A. W.

Publication type:

Article

Direct suppression of autoreactive lymphocytes in the central nervous system via the CB2 receptor.

Published in:

2008

By:

Dittel, B. N.

Publication type:

journal article

Δ9-Tetrahydrocannabinol (THC) and AM 404 protect against cerebral ischaemia in gerbils through a mechanism involving cannabinoid and opioid receptors.

Published in:

British Journal of Pharmacology, 2007, v. 152, n. 8, p. 1301, doi. 10.1038/sj.bjp.0707514

By:

Zani, A.;
Braida, D.;
Capurro, V.;
Sala, M.

Publication type:

Article

Tetrahydrocannabinol-induced neurotoxicity depends on CB[sub1] receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons.

Published in:

British Journal of Pharmacology, 2003, v. 140, n. 3, p. 547, doi. 10.1038/sj.bjp.0705464

By:

Downer, Eric J.;
Fogarty, Marie P.;
Campbell, Veronica A.

Publication type:

Article

Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.

Published in:

2003

By:

Klegeris, Andis;
Bissonnette, Christopher J.;
McGeer, Patrick L.

Publication type:

journal article

The extracellular regulated kinases (ERK) 1/2 mediate cannabinoid-induced inhibition of gap junctional communication in endothelial cells.

Published in:

2002

By:

Brandes, R.P.;
Popp, R.;
Ott, G.;
Bredenkötter, D.;
Wallner, C.;
Busse, R.;
Fleming, L.;
Bredenkötter, D;
Fleming, I

Publication type:

journal article

Cannabinoïdes de synthèse : repérage et prise en charge en soins primaires.

Published in:

Médecine, 2024, v. 20, n. 2, p. 63, doi. 10.1684/med.2024.960

By:

Frances, Pierre;
Nguyen, Quoc-Tuan;
Brunel, Manuela;
Alaoui Mhamdi, Hiba;
Gaubert, Robert;
Rinuy, Claire-Aimée

Publication type:

Article

Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice.

Published in:

Nature, 2005, v. 434, n. 7034, p. 782, doi. 10.1038/nature03389

By:

Steffens, Sabine;
Veillard, Niels R.;
Arnaud, Claire;
Pelli, Graziano;
Burger, Fabienne;
Staub, Christian;
Zimmer, Andreas;
Frossard, Jean-Louis;
Mach, François

Publication type:

Article

Cannabis: Substance that heals or substance that kills.

Published in:

IAHRW International Journal of Social Sciences Review, 2021, v. 9, n. 4, p. 466

By:

Shah, Mohammad Akmal;
Sengar, K. S.

Publication type:

Article