Can Crystal Symmetry and Packing Influence the Active Site Conformation of Homohexameric Purine Nucleoside Phosphorylases?
- Published in:
- Croatica Chemica Acta, 2016, v. 89, n. 2, p. 197, doi. 10.5562/cca2872
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- Article
Works matching Purine nucleoside phosphorylase
Results: 449
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New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A
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- FEBS Letters, 2012, v. 586, n. 7, p. 967, doi. 10.1016/j.febslet.2012.02.039
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- Article
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Single Tryptophan of Disordered Loop from Plasmodium falciparum Purine Nucleoside Phosphorylase: Involvement in Catalysis and Microenvironment.
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- Applied Biochemistry & Biotechnology, 2013, v. 170, n. 4, p. 868, doi. 10.1007/s12010-013-0228-9
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4
Site-Selective Ribosylation of Fluorescent Nucleobase Analogs Using Purine-Nucleoside Phosphorylase as a Catalyst: Effects of Point Mutations.
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- Molecules, 2016, v. 21, n. 1, p. 44, doi. 10.3390/molecules21010044
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- Article
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Enzymatic Synthesis of Highly Fluorescent 8-Azapurine Ribosides Using a Purine Nucleoside Phosphorylase Reverse Reaction: Variable Ribosylation Sites.
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- Molecules, 2013, v. 18, n. 10, p. 12587, doi. 10.3390/molecules181012587
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- Article
6
Development and validation of a 2nd tier test for identification of purine nucleoside phosphorylase deficiency patients during expanded newborn screening by liquid chromatography-tandem mass spectrometry.
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- Clinical Chemistry & Laboratory Medicine, 2016, v. 54, n. 4, p. 627, doi. 10.1515/cclm-2015-0436
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- Article
7
The Role of Phosphate Binding in Purine Nucleoside Phosphorylase of Helicobacter pylori.
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- Croatica Chemica Acta, 2018, v. 91, n. 2, p. 171, doi. 10.5562/cca3335
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- Article
8
Still a Long Way to Fully Understanding the Molecular Mechanism of Escherichia coli Purine Nucleoside Phosphorylase.
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- Croatica Chemica Acta, 2013, v. 86, n. 1, p. 117, doi. 10.5562/cca2116
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- Article
9
Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7‐deazahypoxanthine.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2018, v. 74, n. 6, p. 355, doi. 10.1107/S2053230X18006337
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- Article
10
Purine nucleoside phosphorylase and the enzymatic antioxidant defense system in breast milk from women with different levels of arsenic exposure.
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- Nutrición Hospitalaria, 2015, v. 31, n. 5, p. 2289, doi. 10.3305/nh.2015.31.5.8485
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The First Report of a Pregnancy in a Patient with Purine Nucleoside Phosphorylase Deficiency.
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- 2017
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- Case Study
12
The First Report of a Pregnancy in a Patient with Purine Nucleoside Phosphorylase Deficiency.
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- 2016
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- Publication type:
- Case Study
13
Two patients with novel missense mutation in the purine nucleoside phosphorylase gene without serious or recurrent infections.
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- Clinical & Experimental Neuroimmunology, 2016, v. 7, n. 1, p. 79, doi. 10.1111/cen3.12254
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- Article
14
Tricyclic nitrogen base 1,N -ethenoadenine and its ribosides as substrates for purine-nucleoside phosphorylases: Spectroscopic and kinetic studies.
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- Nucleosides, Nucleotides & Nucleic Acids, 2018, v. 37, n. 2, p. 89, doi. 10.1080/15257770.2017.1419255
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- Article
15
A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency.
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- Pediatric Transplantation, 2015, v. 19, n. 2, p. E47, doi. 10.1111/petr.12413
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- Article
16
A purine nucleoside phosphorylase in Solanum tuberosum L. (potato) with specificity for cytokinins contributes to the duration of tuber endodormancy.
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- Biochemical Journal, 2014, v. 458, n. 2, p. 225, doi. 10.1042/BJ20130792
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- Article
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Purification, crystallization, and preliminary X-ray diffraction study of purine nucleoside phosphorylase from E. coli.
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- Crystallography Reports, 2015, v. 60, n. 4, p. 521, doi. 10.1134/S1063774515040021
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- Article
18
Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.
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- Science Translational Medicine, 2019, v. 11, n. 473, p. N.PAG, doi. 10.1126/scitranslmed.aau3174
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- Article
19
Structural Determinants of the 5′-Methylthioinosine Specificity of <i>Plasmodium</i> Purine Nucleoside Phosphorylase.
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- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084384
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- Article
20
Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.
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- Journal of Neurochemistry, 2017, v. 141, n. 2, p. 208, doi. 10.1111/jnc.14004
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- Article
21
In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.
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- Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 2, p. 321, doi. 10.1007/s00280-012-1908-9
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- Article
22
Functional and Structural Characterization of Purine Nucleoside Phosphorylase from Kluyveromyces lactis and Its Potential Applications in Reducing Purine Content in Food.
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- PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164279
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- Publication type:
- Article
23
Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides.
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- Chemistry - A European Journal, 2015, v. 21, n. 38, p. 13401, doi. 10.1002/chem.201501334
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- Article
24
Genetic Variation in Genes Associated with Arsenic Metabolism: Glutathione S-Transferase Omega 1-1 and Purine Nucleoside Phosphorylase Polymorphisms in European and Indigenous Americans.
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- Environmental Health Perspectives, 2003, v. 111, n. 11, p. 1421, doi. 10.1289/ehp.6420
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- Article
25
Plasmodium falciparum Parasites Are Killed by a Transition State Analogue of Purine Nucleoside Phosphorylase in a Primate Animal Model.
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- PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0026916
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- Article
26
Fusion expression of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase for the synthesis of purine nucleoside products.
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- Chinese Journal of Bioprocess Engineering, 2021, v. 19, n. 1, p. 8, doi. 10.3969/j.issn.1672-3678.2021.01.002
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- Article
27
Novel missense mutation in the purine nucleoside phosphorylase gene in a Japanese patient with purine nucleoside phosphorylase deficiency.
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- Pediatrics International, 2002, v. 44, n. 3, p. 333, doi. 10.1046/j.1442-200X.2002.01543.x
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- Article
28
Tri-Cyclic Nucleobase Analogs and Their Ribosides as Substrates of Purine-Nucleoside Phosphorylases. II Guanine and Isoguanine Derivatives.
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- Molecules, 2019, v. 24, n. 8, p. 1493, doi. 10.3390/molecules24081493
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- Article
29
Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease.
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- Journal of Periodontal Research, 2010, v. 45, n. 5, p. 664, doi. 10.1111/j.1600-0765.2010.01282.x
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- Article
30
Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs.
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- FEBS Open Bio, 2015, v. 5, p. 634, doi. 10.1016/j.fob.2015.07.007
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- Article
31
Çocuklarda sık yineleyen enfeksiyonlar, nörolojik bulgular, serum ürik asit düşüklüğü ve lenfopeni: Pürin nükleozid fosforilaz eksikliği, çocukluk çağı acil hastalıklarından biri.
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- Türk Pediatri Arşivi, 2020, v. 55, n. 3, p. 320, doi. 10.14744/TurkPediatriArs.2019.83788
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- Article
32
H票吟核昔磷酸化酶/疇呢核昔磷酸化酶共表达及固定化催化合成阿糖核昔.
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- Chinese Journal of Bioprocess Engineering, 2024, v. 22, n. 2, p. 139, doi. 10.3969/j.issn.1672-3678.2024.02.003
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- Article
33
Purine Nucleoside Phosphorylase Deficiency in a Patient With Spastic Paraplegia and Recurrent Infections.
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- Journal of Child Neurology, 2007, v. 22, n. 6, p. 741, doi. 10.1177/0883073807302617
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- Article
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Purine Nucleoside Phosphorylase Deficiency in Two Unrelated Patients with Autoimmune Hemolytic Anemia and Eosinophilia: Two Novel Mutations.
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- Archives of Iranian Medicine (AIM), 2023, v. 26, n. 12, p. 712, doi. 10.34172/aim.2023.105
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35
Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding.
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- FEBS Journal, 2009, v. 276, n. 20, p. 5799, doi. 10.1111/j.1742-4658.2009.07247.x
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- Article
36
Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.
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- FEBS Journal, 2007, v. 274, n. 10, p. 2482, doi. 10.1111/j.1742-4658.2007.05784.x
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- Publication type:
- Article
37
Suicide gene therapy-mediated purine nucleoside phosphorylase/fludarabine system for in vitro breast cancer model with emphasis on evaluation of vascular endothelial growth factor promoter efficacy.
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- 3 Biotech, 2021, v. 11, n. 3, p. 1, doi. 10.1007/s13205-021-02692-0
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- Article
38
Purine nucleoside phosphorylase from Pseudoalteromonas sp. Bsi590: molecular cloning, gene expression and characterization of the recombinant protein.
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- Extremophiles, 2008, v. 12, n. 3, p. 325, doi. 10.1007/s00792-007-0131-9
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- Article
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Purine Nucleoside Phosphorylase (PNP) as a Biomarker and Therapeutic Target in Muscle-Invasive Bladder Cancer.
- Published in:
- Clinical Medicine Insights: Oncology, 2025, p. 1, doi. 10.1177/11795549251359145
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- Article
40
Tricyclic Nucleobase Analogs and Their Ribosides as Substrates and Inhibitors of Purine-Nucleoside Phosphorylases III. Aminopurine Derivatives.
- Published in:
- Molecules, 2020, v. 25, n. 3, p. 681, doi. 10.3390/molecules25030681
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- Publication type:
- Article
41
Identification of Purine Nucleoside Phosphorylase Deficiency in Dried Blood Spots by a Non-Radiochemical Assay Using Reversed-Phase High-Performance Liquid Chromatography.
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- Nucleosides, Nucleotides & Nucleic Acids, 2010, v. 29, n. 4-6, p. 466, doi. 10.1080/15257771003741455
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- Article
42
Interactions of Calf Spleen Purine Nucleoside Phosphorylase with Formycin B and its Aglycone - Spectroscopic and Kinetic Studies.
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- Nucleosides, Nucleotides & Nucleic Acids, 2007, v. 26, n. 6/7, p. 849, doi. 10.1080/15257770701503993
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- Article
43
Spectroscopic and Kinetic Studies of Interactions of Calf Spleen Purine Nucleoside Phosphorylase with 8-Azaguanine, and Its 9-(2-Phosphonylmethoxyethyl) Derivative.
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- Nucleosides, Nucleotides & Nucleic Acids, 2005, v. 24, n. 5-7, p. 459, doi. 10.1081/NCN-200060004
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- Article
44
Interactions of Potent Multisubstrate Analogue Inhibitors with Purine Nucleoside Phosphorylase from Calf Spleen—Kinetic and Spectrofluorimetric Studies.
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- Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1567, doi. 10.1081/NCN-120023035
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- Publication type:
- Article
45
Interactions of Trimeric Purine Nucleoside Phosphorylases with Ground State Analogues—Calorimetric and Fluorimetric Studies.
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- Nucleosides, Nucleotides & Nucleic Acids, 2003, v. 22, n. 5-8, p. 1695, doi. 10.1081/NCN-120023116
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- Article
46
The First Purine Nucleoside Phosphorylase Deficiency Patient Resembling IgA Deficiency and a Review of the Literature.
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- Immunological Investigations, 2019, v. 48, n. 4, p. 410, doi. 10.1080/08820139.2019.1570249
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- Article
47
Design and directed evolution of a dideoxy purine nucleoside phosphorylase.
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- PEDS: Protein Engineering, Design & Selection, 2010, v. 23, n. 8, p. 607, doi. 10.1093/protein/gzq033
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- Article
48
Low-molecular-mass purine nucleoside phosphorylase: characterization and application in enzymatic synthesis of nucleoside antiviral drugs.
- Published in:
- Biotechnology Letters, 2011, v. 33, n. 6, p. 1107, doi. 10.1007/s10529-011-0535-6
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- Article
49
Tumor-targeting Salmonella typhimurium, a natural tool for activation of prodrug 6MePdR and their combination therapy in murine melanoma model.
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- Applied Microbiology & Biotechnology, 2013, v. 97, n. 10, p. 4393, doi. 10.1007/s00253-012-4321-8
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- Article
50
Early Diagnosis and Treatment of Purine Nucleoside Phosphorylase (PNP) Deficiency through TREC-Based Newborn Screening.
- Published in:
- International Journal of Neonatal Screening (IJNS), 2021, v. 7, n. 4, p. 62, doi. 10.3390/ijns7040062
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- Publication type:
- Article