Works matching Protein-tyrosine kinase inhibitors

Results: 5000

The Protein Tyrosine Kinase Inhibitor Tyrphostin 23 Strongly Accelerates Glycolytic Lactate Production in Cultured Primary Astrocytes.

Published in:

Neurochemical Research, 2016, v. 41, n. 10, p. 2607, doi. 10.1007/s11064-016-1972-3

By:

Blumrich, Eva-Maria;
Kadam, Reshma;
Dringen, Ralf

Publication type:

Article

Insights into Lipid-Based Delivery Nanosystems of Protein-Tyrosine Kinase Inhibitors for Cancer Therapy.

Published in:

Pharmaceutics, 2022, v. 14, n. 12, p. 2706, doi. 10.3390/pharmaceutics14122706

By:

Jampilek, Josef;
Kralova, Katarina

Publication type:

Article

Structure--Activity Relationship of Halophenols as a New Class of Protein Tyrosine Kinase Inhibitors.

Published in:

International Journal of Molecular Sciences, 2011, v. 12, n. 9, p. 6104, doi. 10.3390/ijms12096104

By:

Feng, Xiu E.;
Wan Yi Zhao;
Shu Rong Ban;
Cheng Xiao Zhao;
Qing Shan Li;
Wen Han Lin

Publication type:

Article

The Hypothalamic Proline-Rich Polypeptide-1 (Galarmin) and its Analogue d-15 are the Inhibitors of Protein Tyrosine Kinase Activity at Cyclophosphamide-Induced Lymphocytopenia.

Published in:

2012

By:

Kirakosova, Aida;
Abrahamyan, Silva;
Tumasyan, Narine;
Davtyan, Tigran;
Khachatryan, Anahit;
Galoyan, Armen

Publication type:

Report

The protein tyrosine kinase inhibitor genistein suppresses hypoxia-induced atrial natriuretic peptide secretion mediated by the PI3K/Akt-HIF-1α pathway in isolated beating rat atria.

Published in:

Canadian Journal of Physiology & Pharmacology, 2021, v. 99, n. 11, p. 1184, doi. 10.1139/cjpp-2020-0503

By:

Zhang, Qiu-li;
Li, Ping;
Hong, Lan;
Li, Rui-zhuang;
Wang, Jia-qi;
Cui, Xun

Publication type:

Article

A meta-analysis: the clinical value of PD-1 inhibitor or protein tyrosine kinase inhibitors in the treatment of advanced osteosarcoma.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1148735

By:

Binhao Shi;
Junli Chang;
Xingyuan Sun;
Xiaoping Ma;
Peng Zhao;
Chujie Zhou;
Yongjun Wang;
Yanping Yang

Publication type:

Article

İmatinibin Sıçan Karaciğerine Etkisi.

Published in:

Medical Bulletin of Haseki / Haseki Tip Bulteni, 2021, v. 59, n. 1, p. 58, doi. 10.4274/haseki.galenos.2021.6667

By:

Kuyucu, Yurdun;
Sencar, Leman

Publication type:

Article

Inhibition of fast sodium current in rabbit ventricular myocytes by protein tyrosine kinase inhibitors.

Published in:

Pflügers Archiv: European Journal of Physiology, 2003, v. 446, n. 4, p. 485, doi. 10.1007/s00424-003-1061-8

By:

Yanggan Wang;
Wagner, Mary B.;
Kumar, Rajiv;
Jun Cheng;
Joyner, Ronald W.

Publication type:

Article

Response to Pralsetinib in Multi-Drug-Resistant Breast Cancer With CCDC6-RET Mutation.

Published in:

Oncologist, 2023, v. 28, n. 6, p. e416, doi. 10.1093/oncolo/oyad115

By:

Zhao, Jing;
Xu, Wei;
Zhuo, Xiaoli;
Liu, Lei;
Zhang, Junlei;
Jiang, Fengxian;
Shen, Yanru;
Lei, Yan;
Hou, Dongsheng;
Lin, Xiaoyan;
Wang, Cuiyan;
Fu, Guobin

Publication type:

Article

Protein Tyrosine Kinases: From Inhibitors to Useful Drugs.

Published in:

2006

By:

Blumenthal, Donald K.

Publication type:

Book Review

Boron-Based Drug Design.

Published in:

Chemical Record, 2015, v. 15, n. 3, p. 616, doi. 10.1002/tcr.201402100

By:

Ban, Hyun Seung;
Nakamura, Hiroyuki

Publication type:

Article

Genistein, a protein tyrosine kinase inhibitor, suppresses the fusogenicity of Moloney murine leukemia virus envelope protein in XC cells.

Published in:

Archives of Virology, 2003, v. 148, n. 10, p. 1899, doi. 10.1007/s00705-003-0164-z

By:

Kubo, Y.;
Ishimoto, A.;
Amanuma, H.

Publication type:

Article

Extranodal marginal zone B-cell lymphoma arising in chronic myeloid leukaemia successfully treated with tyrosine kinase inhibitor: a case report.

Published in:

Hippokratia, 2016, v. 20, n. 3, p. 241

By:

G., Mihaylov;
V., Varbanova;
V., Stoeva;
T., Dikov

Publication type:

Article

Genistein and Curcumin Block TGF-β1-Induced u-PA Expression and Migratory and Invasive Phenotype in Mouse Epidermal Keratinocytes.

Published in:

Nutrition & Cancer, 2000, v. 37, n. 1, p. 49, doi. 10.1207/S15327914NC3701_6

By:

Santibanez, Juan F.;
Quintanilla, Miguel;
Martinez, Jorge

Publication type:

Article

Deciphering the resistance mechanism of RET kinase mutant against vandetanib and nintedanib using molecular dynamics simulations.

Published in:

Journal of Experimental Nanoscience, 2021, v. 16, n. 1, p. 278, doi. 10.1080/17458080.2021.1970141

By:

Zheng, Guodong;
Xu, Shenqian;
Liu, Wuxia;
Du, Tingting;
Zhang, Jingfeng;
Li, Minyu;
Cai, Chen;
Shi, Hong

Publication type:

Article

Nilotinib-Associated Destructive Thyroiditis.

Published in:

Case Reports in Endocrinology, 2015, v. 2015, p. 1, doi. 10.1155/2015/736092

By:

Bakerywala, Suhalia;
Schwarcz, Monica D.;
Goldberg, Michael D.;
Valiquette, Guy;
Weiss, Irene A.

Publication type:

Article

Efficacy of dasatinib in a chronic myeloid leukemia patient with disease molecular relapse and chronic GVHD after haploidentical BMT: an immunomodulatory effect?

Published in:

2009

By:

Breccia, M.;
Cannella, L.;
Stefanizzi, C.;
Carotti, A.;
Santopietro, M.;
Alimena, G.

Publication type:

Case Study

Protein tyrosine phosphatases as potential therapeutic targets.

Published in:

Acta Pharmacologica Sinica, 2014, v. 35, n. 10, p. 1227, doi. 10.1038/aps.2014.80

By:

He, Rong-jun;
Yu, Zhi-hong;
Zhang, Ruo-yu;
Zhang, Zhong-yin

Publication type:

Article

Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives.

Published in:

Acta Pharmacologica Sinica, 2006, v. 27, n. 9, p. 1259, doi. 10.1111/j.1745-7254.2006.00437.x

By:

Jian Li;
Jin-zhi Tan;
Li-li Chen;
Jian Zhang;
Xu Shen;
Chang-lin Mei;
Li-li Fu;
Li-ping Lin;
Jian Ding;
Bing Xiong;
Xi-shan Xiong;
Hong Liu;
Xiao-min Luo;
Hua-liang Jiang

Publication type:

Article

The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00188-x

By:

Shen, Tao;
Hu, Xueqing;
Liu, Xuan;
Subbiah, Vivek;
Mooers, Blaine H. M.;
Wu, Jie

Publication type:

Article

Mutagenesis.

Published in:

Cytogenetics & Cell Genetics, 1998, v. 81, n. 2, p. 159, doi. 10.1159/000015017

By:

Natarajan

Publication type:

Article

Phase I clinical trial combining imatinib mesylate and IL-2 in refractory cancer patients: IL-2 interferes with the pharmacokinetics of imatinib mesylate.

Published in:

OncoImmunology, 2013, v. 2, n. 2, p. e23079-1, doi. 10.4161/onci.23079

By:

Pautier, Patricia;
Locher, Clara;
Robert, Caroline;
Deroussent, Alain;
Flament, Caroline;
Le Cesne, Axel;
Rey, Annie;
Bahleda, Ratislav;
Ribrag, Vincent;
Soria, Jean-Charles;
Vassal, Gilles;
Eggermont, Alexander;
Zitvogel, Laurence;
Chaput, Nathalie;
Paci, Angelo

Publication type:

Article

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.

Published in:

Clinical Science, 2021, v. 135, n. 19, p. 2243, doi. 10.1042/CS20210604

By:

Elksnis, Andris;
Schiffer, Tomas A.;
Palm, Fredrik;
Yun Wang;
Jing Cen;
Turpaev, Kyril;
Ngamjariyawat, Anongnad;
Younis, Shady;
Suling Huang;
Yu Shen;
Ying Leng;
Bergsten, Peter;
Karlsborn, Tony;
Welsh, Nils;
Xuan Wang

Publication type:

Article

Multidrug resistance in chronic myeloid leukemia.

Published in:

Turkish Journal of Biology, 2014, v. 38, n. 6, p. 806, doi. 10.3906/biy-1405-21

By:

ÜNLÜ, Miray;
KİRAZ, Yağmur;
KACI, Fatma Necmiye;
ÖZCAN, Mehmet Ali;
BARAN, Yusuf

Publication type:

Article

Imatinib Mesylate.

Published in:

Clinical Journal of Oncology Nursing, 2002, v. 6, n. 2, p. 118, doi. 10.1188/02.CJON.118-120

By:

Davey, Monica P.;
Wilkinson, Kathy

Publication type:

Article

Total Synthesis and Structural Revision of Clavilactone D.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 16, p. 3828, doi. 10.1002/chem.201700483

By:

Takao, Ken-ichi;
Nemoto, Ryuichi;
Mori, Kento;
Namba, Ayumi;
Yoshida, Keisuke;
Ogura, Akihiro

Publication type:

Article

Effect of synthetic and natural protein tyrosine kinase inhibitors on auxin efflux in zucchini (Cucurbita pepo) hypocotyls.

Published in:

Physiologia Plantarum, 1996, v. 96, n. 2, p. 205, doi. 10.1111/j.1399-3054.1996.tb00203.x

By:

Bernasconi, Paul

Publication type:

Article

Effects of Protein Tyrosine Kinase Inhibitors on the Replication of Herpes Simplex Virus and the Phosphorylation of Viral Proteins.

Published in:

Intervirology, 1997, v. 40, n. 1, p. 7, doi. 10.1159/000150515

By:

Yura, Y.;
Kusaka, J.;
Tsujimoto, H.;
Yoshioka, Y.;
Yoshida, H.;
Sato, M.

Publication type:

Article

The Resveratrol-induced Relaxation of Cholecystokinin Octapeptide- or KCl-induced Tension in Male Guinea Pig Gallbladder Strips Is Mediated Through L-type Ca<sup>2+</sup> Channels.

Published in:

Journal of Neurogastroenterology & Motility, 2015, v. 21, n. 1, p. 62, doi. 10.5056/jnm14093

By:

Kline, Loren W.;
Karpinski, Edward

Publication type:

Article

Protein tyrosine kinase inhibitors block the stimulatory actions of phosphotyrosine phosphatase inhibitors to increase cell proliferation, alkaline phosphatase activity, and collagen synthesis in normal human bone cells.

Published in:

2000

By:

Yoon, Hyun Koo;
Baylink, David J.;
Lau, K.-H. William;
Yoon, H K;
Baylink, D J;
Lau, K H

Publication type:

journal article

ENHANCED TYROSINE PHOSPHORYLATION OF THE DELTA OPIOID RECEPTOR (DOR) IS ASSOCIATED WITH ITS DESENSITIZATION AND INTERNALIZATION.

Published in:

1999

By:

Kramer, Ken;
Simon, Eric J.

Publication type:

Abstract

Targeting tumour microenvironment by tyrosine kinase inhibitor.

Published in:

Molecular Cancer, 2018, v. 17, p. 1, doi. 10.1186/s12943-018-0800-6

By:

Tan, Hor-Yue;
Wang, Ning;
Lam, Wing;
Guo, Wei;
Feng, Yibin;
Cheng, Yung-Chi

Publication type:

Article

Development of inhibitors for protein tyrosine kinases.

Published in:

Oncogene, 2000, v. 19, n. 49, p. 5690, doi. 10.1038/sj.onc.1203926

By:

Al-Obeidi, Fahad A;
Lam, Kit S

Publication type:

Article

Disseminated Erythematous and Pityriasiform Plaques Caused by Imatinib Mesylate.

Published in:

Acta Dermato-Venereologica, 2003, v. 83, n. 5, p. 391, doi. 10.1080/00015550310012593

By:

Pasmatzi, E.;
Monastirli, A.;
Matsouka, P.;
Tsambaos, D.

Publication type:

Article

Pyk2 regulates sepsis-induced lung injury via ferroptosis.

Published in:

Iranian Journal of Basic Medical Sciences, 2023, v. 26, n. 11, p. 1283, doi. 10.22038/IJBMS.2023.69578.15153

By:

Jia Wang;
Pengtao Bao;
Yugeng Liu

Publication type:

Article

Promoting reactive oxygen species accumulation to overcome tyrosine kinase inhibitor resistance in cancer.

Published in:

Cancer Cell International, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12935-024-03418-x

By:

Lin, Wei;
Wang, Xiaojun;
Diao, Mingxin;
Wang, Yangwei;
Zhao, Rong;
Chen, Jiaping;
Liao, Yongde;
Long, Qinghong;
Meng, Yunchong

Publication type:

Article

Sunitinib treatment for patients with clear-cell metastatic renal cell carcinoma: clinical outcomes and plasma angiogenesis markers.

Published in:

BMC Cancer, 2009, v. 9, p. 1, doi. 10.1186/1471-2407-9-82

By:

Kontovinis, Loukas F.;
Papazisis, Konstantinos T.;
Touplikioti, Panagiota;
Andreadis, Charalambos;
Mouratidou, Despoina;
Kortsaris, Alexandros H.

Publication type:

Article

The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases.

Published in:

Biochemical Journal, 2015, v. 465, n. 2, p. 271, doi. 10.1042/BJ20141165

By:

Ozanne, James;
Prescott, Alan R.;
Clark, Kristopher

Publication type:

Article

Requirement of Syk-phospholipase C-γ2 pathway for phorbol ester-induced phospholipase D activation in DT40 cells.

Published in:

Genes to Cells, 2001, v. 6, n. 5, p. 475, doi. 10.1046/j.1365-2443.2001.00434.x

By:

Hitomi, Tomohiro;
Yanagi, Shigeru;
Inatome, Ryoko;
Ding, Junyi;
Takano, Tomoko;
Yamamura, Hirohei

Publication type:

Article

Inhibition of PI3K/mTOR Overcomes Nilotinib Resistance in BCR-ABL1 Positive Leukemia Cells through Translational Down-Regulation of MDM2.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083510

By:

Ding, Jie;
Romani, Julia;
Zaborski, Margarete;
MacLeod, Roderick A. F.;
Nagel, Stefan;
Drexler, Hans G.;
Quentmeier, Hilmar

Publication type:

Article

The Promising Impact of Ibrutinib, a Bruton's Tyrosine Kinase Inhibitor, for the Management of Lymphoid Malignancies.

Published in:

Pharmacotherapy, 2014, v. 34, n. 3, p. 303, doi. 10.1002/phar.1366

By:

Bhatt, Valkal;
Alejandro, Linh;
Michael, Angela;
Ganetsky, Alex

Publication type:

Article

Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00563-4

By:

Subbiah, Vivek;
Gouda, Mohamed A.;
Iorgulescu, J. Bryan;
Dadu, Ramona;
Patel, Keyur;
Sherman, Steven;
Cabanillas, Maria;
Hu, Mimi;
Castellanos, Luz E.;
Amini, Behrang;
Meric-Bernstam, Funda;
Shen, Tao;
Wu, Jie

Publication type:

Article

Protein Tyrosine Kinases. From Inhibitors to Useful Drugs.

Published in:

2006

By:

Hochhaus, A.

Publication type:

Book Review

Genetic and Physiological Effects of Insulin on Human Urate Homeostasis.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.713710

By:

Mandal, Asim K.;
Leask, Megan P.;
Estiverne, Christopher;
Choi, Hyon K.;
Merriman, Tony R.;
Mount, David B.

Publication type:

Article

Mycosis fungoides-like reaction in a patient treated with Gleevec.

Published in:

Journal of Cutaneous Pathology, 2003, v. 30, n. 4, p. 279, doi. 10.1046/j.0303-6987.2003.053.x

By:

Clark, Sandra H.;
Duvic, Madeleine;
Prietol, Victor G.

Publication type:

Article

Conjugation-free, visual, and quantitative evaluation of inhibitors on protein tyrosine kinases and phosphatases with a luminescent Tb(III) complex.

Published in:

Analytical & Bioanalytical Chemistry, 2014, v. 406, n. 12, p. 2957, doi. 10.1007/s00216-014-7707-x

By:

Akiba, Hiroki;
Sumaoka, Jun;
Hamakubo, Takao;
Komiyama, Makoto

Publication type:

Article

Effect of genistein upon capacitation of cryopreserved bovine spermatozoa.

Published in:

Andrologia, 2003, v. 35, n. 1, p. 2, doi. 10.1046/j.1439-0272.2003.00531_1.x

By:

Aires, V. A.;
Hinsch, E.;
Hinsch, K.-D.

Publication type:

Article

Inhibition of motility of hamster spermatozoa by protein tyrosine kinase inhibitors.

Published in:

Andrologia, 2000, v. 32, n. 2, p. 95, doi. 10.1046/j.1439-0272.2000.00331.x

By:

Uma Devi;
Jha;
Patil;
Padma;
Shivaji;
Shivaji

Publication type:

Article

金雀异黄酮对冻融猪精子蛋白酪氨酸磷酸化及获能相关基因表达的影响.

Published in:

Southwest China Journal of Agricultural Sciences, 2021, v. 34, n. 8, p. 1815, doi. 10.16213/j.cnki.scjas.2021.8.033

By:

梁莹莹;
谢运法;
胡传活;
陈志英;
邓祝新;
冯显钤;
许春荣;
刘德玉;
唐胤晟;
李铭

Publication type:

Article

Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug–Drug Interaction Predictions.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 7, p. 1273, doi. 10.1002/psp4.70052

By:

Wu, Yali;
Loer, Helena Leonie Hanae;
Zhang, Yifan;
Zhong, Dafang;
Jiang, Yong;
Hu, Jie;
Fuhr, Uwe;
Lehr, Thorsten;
Diao, Xingxing

Publication type:

Article