Works matching Osteoclast inhibition

Results: 734

Cationic Hydroxyethyl Cellulose Nanocomplexes and RANK siRNA/Zoledronate Co-Delivery Systems for Osteoclast Inhibition.

Published in:

Pharmaceutics, 2024, v. 16, n. 12, p. 1623, doi. 10.3390/pharmaceutics16121623

By:

Lee, Sohyun;
Park, Seoyeon;
Kim, Tae-il

Publication type:

Article

Interleukin-4 inhibition of osteoclast differentiation is stronger than that of interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts.

Published in:

Immunology, 2007, v. 120, n. 4, p. 573, doi. 10.1111/j.1365-2567.2006.02538.x

By:

Yamada, Atsushi;
Takami, Masamichi;
Kawawa, Tadaharu;
Yasuhara, Rika;
Zhao, Baohong;
Mochizuki, Ayako;
Miyamoto, Yoichi;
Eto, Tomoo;
Yasuda, Hisataka;
Nakamichi, Yuko;
Kim, Nacksung;
Katagiri, Takenobu;
Suda, Tatsuo;
Kamijo, Ryutaro

Publication type:

Article

Inhibition of Osteoclast Differentiation by Carotenoid Derivatives through Inhibition of the NF-κB Pathway.

Published in:

Antioxidants, 2020, v. 9, n. 11, p. 1167, doi. 10.3390/antiox9111167

By:

Odes-Barth, Shlomit;
Khanin, Marina;
Linnewiel-Hermoni, Karin;
Miller, Yifat;
Abramov, Karina;
Levy, Joseph;
Sharoni, Yoav

Publication type:

Article

Prevention of Wear Particle-Induced Osteolysis by a Novel V-ATPase Inhibitor Saliphenylhalamide through Inhibition of Osteoclast Bone Resorption.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034132

By:

An Qin;
Tak S. Cheng;
Zhen Lin;
Lei Cao;
Shek M. Chim;
Pavlos, Nathan J.;
Jiake Xu;
Ming Hao Zheng;
Ke Rong Dai

Publication type:

Article

MicroRNA‐155 inhibition up‐regulates LEPR to inhibit osteoclast activation and bone resorption via activation of AMPK in alendronate‐treated osteoporotic mice.

Published in:

IUBMB Life, 2019, v. 71, n. 12, p. 1916, doi. 10.1002/iub.2131

By:

Mao, Zhongxuan;
Zhu, Yihai;
Hao, Weimin;
Chu, Chao;
Su, Hongmin

Publication type:

Article

Osteoclast inhibition impairs chondrosarcoma growth and bone destruction.

Published in:

Journal of Orthopaedic Research, 2014, v. 32, n. 12, p. 1562, doi. 10.1002/jor.22714

By:

Otero, Jesse E.;
Stevens, Jeff W.;
Malandra, Allison E.;
Fredericks, Douglas C.;
Odgren, Paul R.;
Buckwalter, Joseph A.;
Morcuende, Jose

Publication type:

Article

Metformin alleviates bone loss in ovariectomized mice through inhibition of autophagy of osteoclast precursors mediated by E2F1.

Published in:

Cell Communication & Signaling, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12964-022-00966-5

By:

Xie, Xudong;
Hu, Liangcong;
Mi, Bobin;
Xue, Hang;
Hu, Yiqiang;
Panayi, Adriana C.;
Endo, Yori;
Chen, Lang;
Yan, Chenchen;
Lin, Ze;
Li, Hui;
Zhou, Wu;
Liu, Guohui

Publication type:

Article

Involvement of the Ca<sup>2+</sup> signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation.

Published in:

Journal of Veterinary Science, 2015, v. 16, n. 2, p. 151, doi. 10.4142/jvs.2015.16.2.151

By:

Yingxiao Fu;
Jianhong Gu;
Yi Wang;
Yan Yuan;
Xuezhong Liu;
Jianchun Bian;
Zong-Ping Liu

Publication type:

Article

Inhibition of Osteoclast Differentiation by the Interleukin (IL)-1 Family Cytokine IL-33.

Published in:

2011

By:

Palmer, Gaby

Publication type:

Opinion

Inhibition of Human Osteoclast Differentiation by Kynurenine through the Aryl-Hydrocarbon Receptor Pathway.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3498, doi. 10.3390/cells10123498

By:

Kim, So-Yeon;
Oh, Younseo;
Jo, Sungsin;
Ji, Jong-Dae;
Kim, Tae-Hwan

Publication type:

Article

Inhibition of lipopolysaccharide‐induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase inhibitors.

Published in:

Journal of Leukocyte Biology, 2017, v. 101, n. 5, p. 1233, doi. 10.1189/jlb.3A1016-433R

By:

Strålberg, Fredrik;
Kassem, Ali;
Kasprzykowski, Franciszek;
Abrahamson, Magnus;
Grubb, Anders;
Lindholm, Catharina;
Lerner, Ulf H.

Publication type:

Article

PDE4 Inhibition Reduced Osteoclast Differentiation in Psoriatic Patients.

Published in:

Life (2075-1729), 2025, v. 15, n. 3, p. 467, doi. 10.3390/life15030467

By:

Raimondo, Annunziata;
Balestrino, Alessia;
Lembo, Serena

Publication type:

Article

PIN1 Inhibition Suppresses Osteoclast Differentiation and Inflammatory Responses.

Published in:

Journal of Dental Research, 2015, v. 94, n. 2, p. 371, doi. 10.1177/0022034514563335

By:

Cho, Y.-A.;
Jue, S.-S.;
Bae, W.-J.;
Heo, S.-H.;
Shin, S.-I.;
Kwon, I.-K.;
Lee, S.-C.;
Kim, E.-C.

Publication type:

Article

Anti-Osteoporotic Effect of Lactobacillus brevis AR281 in an Ovariectomized Mouse Model Mediated by Inhibition of Osteoclast Differentiation.

Published in:

Biology (2079-7737), 2022, v. 11, n. 3, p. 359, doi. 10.3390/biology11030359

By:

Yu, Jing;
Hang, Yiling;
Sun, Wenni;
Wang, Guangqiang;
Xiong, Zhiqiang;
Ai, Lianzhong;
Xia, Yongjun

Publication type:

Article

Production of Matrix-degrading Enzymes and Inhibition of Osteoclast-like Cell Differentiation by Fibroblast-like Cells from the Periodontal Ligament of Human Primary Teeth.

Published in:

Journal of Dental Research, 1999, v. 78, n. 2, p. 681, doi. 10.1177/00220345990780020801

By:

Wu, Y.-M.;
Richards, D. W.;
Rowe, D. J.

Publication type:

Article

Osteoclast inhibition in postmenopausal breast cancer: Is the evidence too strong to ignore?

Published in:

2017

By:

Stopeck, Alison T.

Publication type:

Editorial

Iejimalides Show Anti-Osteoclast Activity via V-ATPase Inhibition.

Published in:

Bioscience, Biotechnology & Biochemistry, 2006, v. 70, n. 6, p. 1364, doi. 10.1271/bbb.50644

By:

Kazami, Sayaka;
Muroi, Makoto;
Kawatani, Makoto;
Kubota, Takaaki;
Usui, Takeo;
Kobayashi, Jun'ichi;
Osada, Hiroyuki

Publication type:

Article

Impact of the SIK3 pathway inhibition on osteoclast differentiation via oxidative phosphorylation.

Published in:

Journal of Bone & Mineral Research, 2024, v. 39, n. 9, p. 1340, doi. 10.1093/jbmr/zjae105

By:

Kamei, Katsuhiko;
Yahara, Yasuhito;
Kim, Jun-Dal;
Tsuji, Mamiko;
Iwasaki, Mami;
Takemori, Hiroshi;
Seki, Shoji;
Makino, Hiroto;
Futakawa, Hayato;
Hirokawa, Tatsuro;
Nguyen, Tran Canh Tung;
Nakagawa, Takashi;
Kawaguchi, Yoshiharu

Publication type:

Article

Inhibition of Osteoclast Differentiation by 1.25‐D and the Calcimimetic KP2326 Reveals 1.25‐D Resistance in Advanced CKD.

Published in:

Journal of Bone & Mineral Research, 2020, v. 35, n. 11, p. 2265, doi. 10.1002/jbmr.4122

By:

Bernardor, Julie;
Flammier, Sacha;
Ranchin, Bruno;
Gaillard, Ségolène;
Platel, Diane;
Peyruchaud, Olivier;
Machuca‐Gayet, Irma;
Bacchetta, Justine

Publication type:

Article

Mechanisms of isorhamnetin inhibition of osteoclast differentiation: insights from molecular dynamics simulations and in vitro / in vivo experiments.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1551257

By:

Zhou, Yi;
Li, Shaoshuo;
Hong, Bowen;
Wang, Zihan;
Shao, Yang;
Wu, Mao;
Wang, Jianwei

Publication type:

Article

Glycosphingolipid synthesis inhibition limits osteoclast activation and myeloma bone disease.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 6, p. 2279, doi. 10.1172/JCI59987

By:

Ersek, Adel;
Ke Xu;
Antonopoulos, Aristotelis;
Butters, Terry D.;
Espirito Santo, Ana;
Vattakuzhi, Youridies;
Williams, Lynn M.;
Goudevenou, Katerina;
Danks, Lynett;
Freidin, Andrew;
Spanoudakis, Emmanouil;
Parry, Simon;
Papaioannou, Maria;
Hatjiharissi, Evdoxia;
Chaidos, Aristeidis;
Alonzi, Dominic S.;
Twigg, Gabriele;
Ming Hu;
Dwek, Raymond A.;
Haslam, Stuart M.

Publication type:

Article

Research Progress on Inhibition of Osteoclast Differentiation by Traditional Chinese Medicine.

Published in:

Pharmacognosy Magazine, 2024, v. 20, n. 4, p. 1179, doi. 10.1177/09731296241228904

By:

Qian, Yanan;
Chong, Siomui;
Chen, Qian;
Yin, Chengliang;
Cao, Yujing

Publication type:

Article

Biochemometry-Based Discovery of Phenylpropanoids from Azadirachta indica Fruits as Inhibitors of In Vitro Osteoclast Formation.

Published in:

Molecules, 2022, v. 27, n. 11, p. 3611, doi. 10.3390/molecules27113611

By:

Tahir, Ammar;
Kampleitner, Carina;
Wirglauer, Theresa;
Grienke, Ulrike;
Hoffmann, Oskar;
Rollinger, Judith M.

Publication type:

Article

Aminobisphosphonates Cause Osteoblast Apoptosis and Inhibit Bone Nodule Formation In Vitro.

Published in:

Calcified Tissue International, 2008, v. 82, n. 3, p. 191, doi. 10.1007/s00223-008-9104-y

By:

Idris, Aymen I.;
Rojas, Javier;
Greig, Iain R.;
van't Hof, Rob J.;
Ralston, Stuart H.

Publication type:

Article

Myeloid Lineage Ablation of Phlpp1 Regulates M-CSF Signaling and Tempers Bone Resorption in Female Mice.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 9702, doi. 10.3390/ijms22189702

By:

Karkache, Ismael Y.;
Damodaran, Jeyaram R.;
Molstad, David H. H.;
Mansky, Kim C.;
Bradley, Elizabeth W.

Publication type:

Article

Integrated computational and in vivo models reveal Key Insights into macrophage behavior during bone healing.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 5, p. 1, doi. 10.1371/journal.pcbi.1009839

By:

Baratchart, Etienne;
Lo, Chen Hao;
Lynch, Conor C.;
Basanta, David

Publication type:

Article

Brief Report: Consecutive Alendronate Administration-Mediated Inhibition of Osteoclasts Improves Long-Term Engraftment Potential and Stress Resistance of HSCs.

Published in:

Stem Cells, 2016, v. 34, n. 10, p. 2601, doi. 10.1002/stem.2425

By:

Sim, Hyun-Jaung;
Kook, Sung-Ho;
Yun, Chi-Young;
Bhattarai, Govinda;
Cho, Eui-Sic;
Lee, Jeong-Chae

Publication type:

Article

Inhibition of osteoclast formation and function by bicarbonate: Role of soluble adenylyl cyclase.

Published in:

Journal of Cellular Physiology, 2009, v. 220, n. 2, p. 332, doi. 10.1002/jcp.21767

By:

WEIDONG GENG;
HILL, KATHY;
ZERWEKH, JOSEPH E.;
KOHLER, THOMAS;
MÜLLER, RALPH;
MOE, ORSON W.

Publication type:

Article

Modified simulated body fluid에 침전한 티타늄 표면에서 침전 기간에 따라 나타나는 파골 세포의 분화억제 양상

Published in:

Journal of Korean Academy of Prosthodontics, 2019, v. 57, n. 2, p. 142, doi. 10.4047/jkap.2019.57.2.142

By:

장현민;
허성주;
김성균;
곽재영

Publication type:

Article

ATRAID regulates the action of nitrogen-containing bisphosphonates on bone.

Published in:

Science Translational Medicine, 2020, v. 12, n. 544, p. 1, doi. 10.1126/scitranslmed.aav9166

By:

Surface, Lauren E.;
Burrow, Damon T.;
Li, Jinmei;
Park, Jiwoong;
Kumar, Sandeep;
Lyu, Cheng;
Song, Niki;
Yu, Zhou;
Rajagopal, Abbhirami;
Bae, Yangjin;
Lee, Brendan H.;
Mumm, Steven;
Gu, Charles C.;
Baker, Jonathan C.;
Mohseni, Mahshid;
Sum, Melissa;
Huskey, Margaret;
Duan, Shenghui;
Bijanki, Vinieth N.;
Civitelli, Roberto

Publication type:

Article

Cissus quadrangularis (Hexane Fraction) Inhibits RANK-L Induced Osteoclast Differentiation of Murine Macrophage RAW264.7 Cell Line.

Published in:

Pakistan Journal of Zoology, 2023, v. 55, n. 6, p. 2707, doi. 10.17582/journal.pjz/20220312001022

By:

Toor, Rabail Hassan;
Tasadduq, Raazia;
Lian, Jane B.;
Stein, Janet L.;
Stein, Gary S.;
Shakoori, Abdul Rauf

Publication type:

Article

Involvement of the mitogen-activated protein kinase signaling pathway in osteoprotegerin-induced inhibition of osteoclast differentiation and maturation.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 5, p. 6939, doi. 10.3892/mmr.2015.4284

By:

YINGXIAO FU;
JIANHONG GU;
YI WANG;
YAN YUAN;
XUEZHONG LIU;
JIANCHUN BIAN;
ZONGPING LIU

Publication type:

Article

Surface proteins of Propionibacterium freudenreichii MJ2 inhibit RANKL-induced osteoclast differentiation by lipocalin-2 upregulation and lipocalin-2-mediated NFATc1 inhibition.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42944-y

By:

Yeom, Jiah;
Ma, Seongho;
Yim, Dong Joon;
Lim, Young-Hee

Publication type:

Article

Surface proteins of Propionibacterium freudenreichii MJ2 inhibit RANKL-induced osteoclast differentiation by lipocalin-2 upregulation and lipocalin-2-mediated NFATc1 inhibition.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42944-y

By:

Yeom, Jiah;
Ma, Seongho;
Yim, Dong Joon;
Lim, Young-Hee

Publication type:

Article

Gelatin-Modified Calcium/Strontium Hydrogen Phosphates Stimulate Bone Regeneration in Osteoblast/Osteoclast Co-Culture and in Osteoporotic Rat Femur Defects—In Vitro to In Vivo Translation.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5103, doi. 10.3390/molecules25215103

By:

Kruppke, Benjamin;
Ray, Seemun;
Alt, Volker;
Rohnke, Marcus;
Kern, Christine;
Kampschulte, Marian;
Heinemann, Christiane;
Budak, Matthäus;
Adam, Josephine;
Döhner, Nils;
Franz-Forsthoffer, Lucretia;
El Khassawna, Thaqif;
Heiss, Christian;
Hanke, Thomas;
Thormann, Ulrich;
Mansell, Jason Peter

Publication type:

Article

Psoralen and Bakuchiol Ameliorate M-CSF Plus RANKL-Induced Osteoclast Differentiation and Bone Resorption Via Inhibition of AKT and AP-1 Pathways in Vitro.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 48, n. 5, p. 2123, doi. 10.1159/000492554

By:

Lijuan Chai;
Kun Zhou;
Shaoxia Wang;
Han Zhang;
Na Fan;
Jie Li;
Xiaofeng Tan;
Limin Hu;
Xiang Fan

Publication type:

Article

Bisphosphonate-related jaw necrosis: A team approach management and prevention.

Published in:

International Journal of Dental Hygiene, 2009, v. 7, n. 2, p. 90, doi. 10.1111/j.1601-5037.2008.00331.x

By:

Rayman, S.;
Almas, K.;
Dincer, E.

Publication type:

Article

Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00437-w

By:

Rong, Kewei;
Wang, Dezheng;
Pu, Xiting;
Zhang, Cheng;
Zhang, Pu;
Cao, Xiankun;
Zheng, Jinglin;
Yang, Xiao;
Liu, Kexin;
Shi, Lei;
Li, Yin;
Ma, Peixiang;
Ye, Dan;
Zhao, Jie;
Wang, Pu;
Qin, An

Publication type:

Article

Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.79966

By:

Riquelme-Guzmán, Camilo;
Tsai, Stephanie L.;
Paz, Karen Carreon;
Nguyen, Congtin;
Oriola, David;
Schuez, Maritta;
Brugués, Jan;
Currie, Joshua D.;
Sandoval-Guzmán, Tatiana

Publication type:

Article

Osteoclastic bone resorption induced by innate immune responses.

Published in:

Periodontology 2000, 2010, v. 54, n. 1, p. 235, doi. 10.1111/j.1600-0757.2010.00355.x

By:

Koide, Masanori;
Kinugawa, Saya;
Takahashi, Naoyuki;
Udagawa, Nobuyuki

Publication type:

Article

Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma.

Published in:

Leukemia (08876924), 2008, v. 22, n. 10, p. 1925, doi. 10.1038/leu.2008.174

By:

Breitkreutz, I.;
Raab, M. S.;
Vallet, S.;
Hideshima, T.;
Raje, N.;
Mitsiades, C.;
Chauhan, D.;
Okawa, Y.;
Munshi, N. C.;
Richardson, P. G.;
Anderson, K. C.

Publication type:

Article

Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy.

Published in:

Orthopaedic Surgery, 2023, v. 15, n. 1, p. 256, doi. 10.1111/os.13584

By:

Liu, Bo;
Gao, Feng;
Xiu, Xiaofei;
Wu, Tao;
Liu, Zeming;
Zhang, Bingshi;
Liu, Sikai;
Han, Yongtai

Publication type:

Article

Effect of Mechanical Strain on Cells Involved in Fracture Healing.

Published in:

Orthopaedic Surgery, 2021, v. 13, n. 2, p. 369, doi. 10.1111/os.12885

By:

Duan, Zheng‐wei;
Lu, Hua

Publication type:

Article

Systemic administration of cytotoxic T lymphocyte‐associated antigen 4 (CTLA‐4)‐Ig abrogates alveolar bone resorption in induced periodontitis through inhibition of osteoclast differentiation and activation: An experimental investigation

Published in:

Journal of Periodontal Research, 2021, v. 56, n. 5, p. 972, doi. 10.1111/jre.12909

By:

Nakane, Saki;
Imamura, Kentaro;
Hisanaga, Rio;
Ishihara, Kazuyuki;
Saito, Atsushi

Publication type:

Article

HSP90 drives the Rab11a‐mediated vesicular transport of the cell surface receptors in osteoclasts.

Published in:

Cell Biochemistry & Function, 2022, v. 40, n. 8, p. 838, doi. 10.1002/cbf.3745

By:

Tran, Manh Tien;
Okusha, Yuka;
Htike, Kaung;
Sogawa, Chiharu;
Eguchi, Takanori;
Kadowaki, Tomoko;
Sakai, Eiko;
Tsukuba, Takayuki;
Okamoto, Kuniaki

Publication type:

Article

Pathophysiology of BRONJ: Drug-related osteoclastic disease of the jaw

Published in:

Oral Science International, 2013, v. 10, n. 1, p. 1, doi. 10.1016/S1348-8643(12)00045-6

By:

Ikebe, Tetsuro

Publication type:

Article

布鲁顿酪氨酸激酶对破骨细胞增殖及分化作用的实验研究.

Published in:

West China Journal of Stomatology, 2019, v. 37, n. 4, p. 361, doi. 10.7518/hxkq.2019.04.004

By:

仉红;
王丽娜;
左美娜;
董明;
史东梅;
徐慧君;
牛卫东

Publication type:

Article

Functionalized Hydroxyapatite and Curcumin Incorporated Stimuli‐Responsive Low‐Exothermic and Injectable Poly(methyl methacrylate) Bone Cement for the Treatment of Osteomyelitis.

Published in:

Advanced Functional Materials, 2024, v. 34, n. 42, p. 1, doi. 10.1002/adfm.202406817

By:

You, Tao;
Ding, Xintian;
Zhao, Huapeng;
Dai, Bin;
Ye, Lei;
Zhao, Heng;
Zhu, Xinwei;
Zhou, Jian;
Yin, Jun

Publication type:

Article

Ablation of cathepsin k activity in the young mouse causes hypermineralization of long bone and growth plates.

Published in:

2009

By:

Boskey, Adele L.;
Gelb, Bruce D.;
Pourmand, Eric;
Kudrashov, Valery;
Doty, Stephen B.;
Spevak, Lyudmila;
Schaffler, Mitchell B.

Publication type:

journal article

A Comparison between the Effects of Hydrophobic and Hydrophilic Statins on Osteoclast Function In Vitro and Ovariectomy-Induced Bone Loss In Vivo.

Published in:

Calcified Tissue International, 2007, v. 81, n. 5, p. 403, doi. 10.1007/s00223-007-9078-1

By:

Hughes, Alun;
Rogers, Michael;
Idris, Aymen;
Crockett, Julie

Publication type:

Article