Works matching Mutation and mutagenesis

Results: 1774

Quantitative evaluation of DNA damage and mutation rate by atmospheric and room-temperature plasma (ARTP) and conventional mutagenesis.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 13, p. 5639, doi. 10.1007/s00253-015-6678-y

By:

Zhang, Xue;
Zhang, Chong;
Zhou, Qian-Qian;
Zhang, Xiao-Fei;
Wang, Li-Yan;
Chang, Hai-Bo;
Li, He-Ping;
Oda, Yoshimitsu;
Xing, Xin-Hui

Publication type:

Article

High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31818-y

By:

Cortés-López, Mariela;
Schulz, Laura;
Enculescu, Mihaela;
Paret, Claudia;
Spiekermann, Bea;
Quesnel-Vallières, Mathieu;
Torres-Diz, Manuel;
Unic, Sebastian;
Busch, Anke;
Orekhova, Anna;
Kuban, Monika;
Mesitov, Mikhail;
Mulorz, Miriam M.;
Shraim, Rawan;
Kielisch, Fridolin;
Faber, Jörg;
Barash, Yoseph;
Thomas-Tikhonenko, Andrei;
Zarnack, Kathi;
Legewie, Stefan

Publication type:

Article

Mutation Induced Extinction in Finite Populations: Lethal Mutagenesis and Lethal Isolation.

Published in:

PLoS Computational Biology, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pcbi.1002609

By:

Wylie, C. Scott;
Shakhnovich, Eugene I.

Publication type:

Article

A machine learning enhanced EMS mutagenesis probability map for efficient identification of causal mutations in Caenorhabditis elegans.

Published in:

PLoS Genetics, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.pgen.1011377

By:

Guo, Zhengyang;
Wang, Shimin;
Wang, Yang;
Wang, Zi;
Ou, Guangshuo

Publication type:

Article

Identification of dominant mutations that confer increased aluminium tolerance through mutagenesis of the Al-sensitive Arabidopsis mutant, als3-1.

Published in:

Journal of Experimental Botany, 2006, v. 57, n. 4, p. 943, doi. 10.1093/jxb/erj080

By:

Gabrielson, Kelly M.;
Cancel, Jesse D.;
Morua, Luis F.;
Larsen, Paul B.

Publication type:

Article

An updated system for the targeted mutagenesis of the psbDI:psbC operon in Synechocystis sp. PCC 6803: mutations targeting Asp460 in CP43 of Photosystem II reduce oxygen-evolving activity and perturb electron transfer in the quinone-Fe-acceptor complex.

Published in:

New Zealand Journal of Botany, 2020, v. 58, n. 4, p. 389, doi. 10.1080/0028825X.2020.1771383

By:

Khaing, Ei Phyo;
Zhong, Victor;
Eaton-Rye, Julian J.

Publication type:

Article

An improved system for the targeted mutagenesis of the psbA2 gene in Synechocystis sp. PCC 6803: mutation of D1-Glu244 to His impairs electron transfer between QA and QB of Photosystem II.

Published in:

New Zealand Journal of Botany, 2019, v. 57, n. 2, p. 125, doi. 10.1080/0028825X.2019.1617321

By:

Forsman, Jack A.;
Winter, Regan T.;
Eaton-Rye, Julian J.

Publication type:

Article

Generation of eight adjacent mutations in a single step using a site-directed mutagenesis kit.

Published in:

Clinical Chemistry & Laboratory Medicine, 2004, v. 42, n. 4, p. 384, doi. 10.1515/CCLM.2004.068

By:

Cabré, Anna;
Girona, Josefa;
Zalba, Guillermo;
Moreno, María-Ujué;
Díez, Javier;
Masana, Lluís

Publication type:

Article

Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast.

Published in:

G3: Genes | Genomes | Genetics, 2024, v. 14, n. 10, p. 1, doi. 10.1093/g3journal/jkae196

By:

Dennen, Matthew S;
Kockler, Zachary W;
Roberts, Steven A;
Burkholder, Adam B;
Klimczak, Leszek J;
Gordenin, Dmitry A

Publication type:

Article

Prediction of the Effects of Missense Mutations on Human Myeloperoxidase Protein Stability Using In Silico Saturation Mutagenesis.

Published in:

Genes, 2022, v. 13, n. 8, p. 1412, doi. 10.3390/genes13081412

By:

Sobitan, Adebiyi;
Edwards, William;
Jalal, Md Shah;
Kolawole, Ayanfeoluwa;
Ullah, Hemayet;
Duttaroy, Atanu;
Li, Jiang;
Teng, Shaolei

Publication type:

Article

Computational Saturation Mutagenesis to Investigate the Effects of Neurexin-1 Mutations on AlphaFold Structure.

Published in:

Genes, 2022, v. 13, n. 5, p. 789, doi. 10.3390/genes13050789

By:

Rhoades, Raina;
Henry, Brianna;
Prichett, Dominique;
Fang, Yayin;
Teng, Shaolei

Publication type:

Article

Random Mutagenesis of β-Tubulin Defines a Set of Dispersed Mutations That Confer Paclitaxel Resistance.

Published in:

Pharmaceutical Research, 2012, v. 29, n. 11, p. 2994, doi. 10.1007/s11095-012-0794-5

By:

Yin, Shanghua;
Zeng, Changqing;
Hari, Malathi;
Cabral, Fernando

Publication type:

Article

Adaptive Resistance Mutations at Suprainhibitory Concentrations Independent of SOS Mutagenesis.

Published in:

Molecular Biology & Evolution, 2021, v. 38, n. 10, p. 4095, doi. 10.1093/molbev/msab196

By:

Gutiérrez, Ricardo;
Ram, Yoav;
Berman, Judith;
Sousa, Keyla Carstens Marques de;
Nachum-Biala, Yaarit;
Britzi, Malka;
Elad, Daniel;
Glaser, Gad;
Covo, Shay;
Harrus, Shimon

Publication type:

Article

Prenatal diagnosis of X-linked hyper-IGM syndrome by direct detection of mutation Q220X in the CD40L gene using PCR-mediated site directed mutagenesis.

Published in:

Prenatal Diagnosis, 2000, v. 20, n. 10, p. 822, doi. 10.1002/1097-0223(200010)20:10<822::AID-PD935>3.0.CO;2-K

By:

Jayoussi-Assalia, R.;
Etzioni, A.;
Notarangelo, L.D.;
Brill-Zamir, R.;
Kasinetz, L.;
Kadouri, E;
Gershoni-Baruch, R.

Publication type:

Article

Site‐directed mutagenesis, expression, purification and translesion synthesis analysis of human DNA polymerase η mutations found in xeroderma pigmentosum variant and melanoma patients.

Published in:

FASEB Journal, 2013, v. 27, p. 976.2, doi. 10.1096/fasebj.27.1_supplement.976.2

By:

Kumar, Mukesh;
Jiang, Xiaohua

Publication type:

Article

A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.

Published in:

2004

By:

Toye, Ayo A.;
Moir, Lee;
Hugill, Alison;
Bentley, Liz;
Quarterman, Julie;
Mijat, Vesna;
Hough, Tertius;
Goldsworthy, Michelle;
Haynes, Alison;
Hunter, A. Jacqueline;
Browne, Mick;
Spurr, Nigel;
Cox, Roger D.

Publication type:

journal article

Zinc finger nucleases for targeted mutagenesis and repair of the sickle-cell disease mutation: An in-silico study.

Published in:: BMC Blood Disorders, 2012, v. 12, n. 1, p. 5, doi. 10.1186/1471-2326-12-5
Publication type:: Article

Amino acid substitutions in random mutagenesis libraries: lessons from analyzing 3000 mutations.

Published in:

Applied Microbiology & Biotechnology, 2017, v. 101, n. 8, p. 3177, doi. 10.1007/s00253-016-8035-1

By:

Zhao, Jing;
Frauenkron-Machedjou, Victorine;
Kardashliev, Tsvetan;
Ruff, Anna;
Zhu, Leilei;
Bocola, Marco;
Schwaneberg, Ulrich

Publication type:

Article

Dependence of Epistasis on Environment and Mutation Severity as Revealed by in Silico Mutagenesis of Phage T7.

Published in:

Genetics, 2002, v. 160, n. 4, p. 1273, doi. 10.1093/genetics/160.4.1273

By:

Lingchong You;
Yin, John

Publication type:

Article

Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87226-7

By:

Suehiro, Yuji;
Yoshina, Sawako;
Motohashi, Tomoko;
Iwata, Satoru;
Dejima, Katsufumi;
Mitani, Shohei

Publication type:

Article

Editorial: Mutational breeding: from induced mutations to site-directed mutagenesis.

Published in:

Frontiers in Plant Science, 2024, p. 1, doi. 10.3389/fpls.2024.1511363

By:

Rasmussen, Søren K.;
Jain, Shri Mohan

Publication type:

Article

Rapid Mutation of Spirulina platensis by a New Mutagenesis System of Atmospheric and Room Temperature Plasmas (ARTP) and Generation of a Mutant Library with Diverse Phenotypes.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077046

By:

Fang, Mingyue;
Jin, Lihua;
Zhang, Chong;
Tan, Yinyee;
Jiang, Peixia;
Ge, Nan;
Heping Li;
Xing, Xinhui

Publication type:

Article

A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption.

Published in:

Mammalian Genome, 2008, v. 19, n. 2, p. 77, doi. 10.1007/s00335-007-9087-4

By:

Pawlak, Cornelius R.;
Sanchis-Segura, Carles;
Soewarto, Dian;
Wagner, Sibylle;
de Angelis, Martin Hrabé;
Spanagel, Rainer

Publication type:

Article

Identification of mutations from phenotype-driven ENU mutagenesis in mouse Chromosome 7.

Published in:

Mammalian Genome, 2005, v. 16, n. 8, p. 555, doi. 10.1007/s00335-005-0032-0

By:

Culiat, Cymbeline T.;
Klebig, Mitchell L.;
Zhaowei Liu;
Monroe, Heidi;
Stanford, Beverly;
Desai, Jayashree;
Tandan, Samvit;
Hughes, Lori;
Kerley, Marilyn K.;
Carpenter, Donald A.;
Johnson, Dabney K.;
Rinchik, Eugene M.;
Qingbo Li

Publication type:

Article

Genomewide two-generation screens for recessive mutations by ES cell mutagenesis.

Published in:

Mammalian Genome, 2004, v. 15, n. 12, p. 960, doi. 10.1007/s00335-004-2406-0

By:

Munroe, Robert;
Ackerman, Susan;
Schimenti, John

Publication type:

Article

TP53 mutations in squamous-cell carcinomas of the conjunctiva: evidence for UV-induced mutagenesis.

Published in:

Mutagenesis, 2004, v. 19, n. 5, p. 399, doi. 10.1093/mutage/geh048

By:

Ateenyi-Agaba, Charles;
Min Dai;
Le Calvez, Florence;
Katongole-Mbidde, Edward;
Smet, Anouk;
Tommasino, Massimo;
Franceschi, Silvia;
Hainaut, Pierre;
Weiderpass, Elisabete

Publication type:

Article

Identification of a Novel Point Mutation of Mouse Proto-Oncogene c-kit Through N-Ethyl-N-nitrosourea Mutagenesis.

Published in:

Genetics, 2005, v. 169, n. 2, p. 819, doi. 10.1534/genetics.104.027177

By:

Hai-Bin Ruan;
Nian Zhang;
Xiang Gao

Publication type:

Article

Population persistence under high mutation rate: From evolutionary rescue to lethal mutagenesis.

Published in:

Evolution, 2019, v. 73, n. 8, p. 1517, doi. 10.1111/evo.13771

By:

Anciaux, Yoann;
Lambert, Amaury;
Ronce, Ophélie;
Roques, Lionel;
Martin, Guillaume

Publication type:

Article

Computational saturation mutagenesis to explore the effect of pathogenic mutations on extra-cellular domains of TREM2 associated with Alzheimer's and Nasu-Hakola disease.

Published in:

Journal of Molecular Modeling, 2023, v. 29, n. 11, p. 1, doi. 10.1007/s00894-023-05770-7

By:

Swain, Preety Sthutika;
Panda, Sunita;
Pati, Sanghamitra;
Dehury, Budheswar

Publication type:

Article

A shifting mutational landscape in 6 nutritional states: Stress-induced mutagenesis as a series of distinct stress input–mutation output relationships.

Published in:

PLoS Biology, 2017, v. 15, n. 6, p. 1, doi. 10.1371/journal.pbio.2001477

By:

Maharjan, Ram P.;
Ferenci, Thomas

Publication type:

Article

Whole exome sequencing reveals a functional mutation in the GAIN domain of the Bai2 receptor underlying a forward mutagenesis hyperactivity QTL.

Published in:

Mammalian Genome, 2017, v. 28, n. 11/12, p. 465, doi. 10.1007/s00335-017-9716-5

By:

Speca, David;
Trimmer, James;
Peterson, Andrew;
Díaz, Elva

Publication type:

Article

Mechanisms of mutagenesis induced by DNA lesions: multiple factors affect mutations in translesion DNA synthesis.

Published in:

2020

By:

Zhang, Huidong

Publication type:

Literature Review

Comprehensive mutagenesis maps the effect of all single-codon mutations in the AAV2 rep gene on AAV production.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87730

By:

Jain, Nina K.;
Ogden, Pierce J.;
Church, George M.

Publication type:

Article

Elucidating PIK3CA‐cooperating mutations in breast cancer using an inducible and mammary‐specific genetic mutagenesis system.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2907

By:

Palisoc, Maryknoll;
Gestl, Shelley;
Gunther, Edward

Publication type:

Article

Identification of candidate cooperative genes of the Apc mutation in transformation of the colon epithelial cell by retroviral insertional mutagenesis.

Published in:

Cancer Science, 2008, v. 99, n. 5, p. 979, doi. 10.1111/j.1349-7006.2008.00757.x

By:

Tanaka, Miwa;
Jin, Guang;
Yamazaki, Yukari;
Takahara, Tomoko;
Takuwa, Miki;
Nakamura, Takuro

Publication type:

Article

Other transgenic mutation assays: A new transgenic mouse mutagenesis test system using Spi− and 6-thioguanine selections.

Published in:

Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 465, doi. 10.1002/(SICI)1098-2280(1996)28:4<465::AID-EM24>3.0.CO;2-C

By:

Nohmi, T.;
Katoh, M.;
Suzuki, H.;
Matsui, M.;
Yamada, M.;
Watanabe, M.;
Suzuki, M.;
Horiya, N.;
Ueda, O.;
Shibuya, T.;
Ikeda, H.;
Sofuni, T.

Publication type:

Article

Mutagenesis and human genetic disease: Dominant mutation frequencies and a characterization of mutational events in mice and humans.

Published in:

Environmental & Molecular Mutagenesis, 1995, v. 25, n. S2, p. 81, doi. 10.1002/em.2850250612

By:

Favor, Jack

Publication type:

Article

Role of mouse germ-cell mutagenesis in understanding genetic risk and in generating mutations that are prime tools for studies in modern biology.

Published in:

Environmental & Molecular Mutagenesis, 1994, v. 23, n. S2, p. 23, doi. 10.1002/em.2850230608

By:

Russell, Liane B.

Publication type:

Article

A Model of Genetic Search for Beneficial Mutations: Estimating the Constructive Capacities of Mutagenesis.

Published in:

Journal of Molecular Evolution, 2011, v. 73, n. 5/6, p. 337, doi. 10.1007/s00239-011-9482-z

By:

Ananko, Grigory

Publication type:

Article

ESI mutagenesis: a one-step method for introducing mutations into bacterial artificial chromosomes.

Published in:

Life Science Alliance, 2021, v. 4, n. 2, p. 1, doi. 10.26508/lsa.202000836

By:

Rondelet, Arnaud;
Pozniakovsky, Andrei;
Namboodiri, Devika;
Silva, Richard Cardoso da;
Singh, Divya;
Leuschner, Marit;
Poser, Ina;
Ssykor, Andrea;
Berlitz, Julian;
Schmidt, Nadine;
Röhder, Lea;
Vader, Gerben;
Hyman, Anthony A.;
Bird, Alexander W.

Publication type:

Article

THE TIMING OF UV MUTAGENESIS IN YEAST: A PEDIGREE ANALYSIS OF INDUCED RECESSIVE MUTATION.

Published in:

Genetics, 1977, v. 87, n. 2, p. 237

By:

JAMES, A. P.;
KILBEY, B. J.

Publication type:

Article

Induction of new mutations in a mouse t-haplotype using ethylnitrosourea mutagenesis.

Published in:

Genetics Research, 1986, v. 47, n. 3, p. 187, doi. 10.1017/S0016672300023119

By:

Justice, Monica J.;
Bode, Vernon C.

Publication type:

Article

Germline mutagenesis, automated meiotic mapping, and the discovery of mutations that suppress disease.

Published in:

Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2021, v. 125, p. 1

By:

Beutler, Bruce A.

Publication type:

Article

ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.

Published in:

BMC Research Notes, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-0500-6-203

By:

Umemori, Juzoh;
Takao, Keizo;
Koshimizu, Hisatsugu;
Hattori, Satoko;
Furuse, Tamio;
Wakana, Shigeharu;
Miyakawa, Tsuyoshi

Publication type:

Article

Site-directed mutagenesis of the T4 endonuclease V Gene: Mutations which enhance enzyme specific activity at low salt concentrations.

Published in:

Proteins, 1989, v. 6, n. 2, p. 128, doi. 10.1002/prot.340060204

By:

Lloyd, R. Stephen;
Augustine, Mary Lou

Publication type:

Article

Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.

Published in:

Nature Genetics, 2002, v. 30, n. 2, p. 185, doi. 10.1038/ng812

By:

Herron, Bruce J.;
Lu, Weining;
Rao, Cherie;
Liu, Shanming;
Peters, Heiko;
Bronson, Roderick T.;
Justice, Monica J.;
McDonald, J. David;
Beier, David R.

Publication type:

Article

Improvement of alkalophilicity of an alkaline xylanase Xyn11A-LC from Bacillus sp. SN5 by random mutation and Glu135 saturation mutagenesis.

Published in:

BMC Biotechnology, 2016, v. 16, p. 1, doi. 10.1186/s12896-016-0310-9

By:

Wenqin Bai;
Yufan Cao;
Jun Liu;
Qinhong Wang;
Zhenhu Jia

Publication type:

Article

Error-prone PCR mutagenesis and reverse bacterial two-hybrid screening identify a mutation in asparagine 53 of the Staphylococcus aureus ESAT6-like component EsxB that perturbs interaction with EsxD.

Published in:

Folia Microbiologica, 2018, v. 63, n. 4, p. 483, doi. 10.1007/s12223-018-0591-6

By:

Ibrahim, Amany M.;
Ragab, Yasser M.;
Aly, Khaled A.;
Ramadan, Mohamed A.

Publication type:

Article

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients.

Published in:

2008

By:

Howe, Steven J.;
Mansour, Marc R.;
Schwarzwaelder, Kerstin;
Bartholomae, Cynthia;
Hubank, Michael;
Kempski, Helena;
Brugman, Martijn H.;
Pike-Overzet, Karin;
Chatters, Stephen J.;
de Ridder, Dick;
Gilmour, Kimberly C.;
Adams, Stuart;
Thornhill, Susannah I.;
Parsley, Kathryn L.;
Staal, Frank J.T.;
Gale, Rosemary E.;
Linch, David C.;
Bayford, Jinhua;
Brown, Lucie;
Quaye, Michelle

Publication type:

journal article

A method for introducing site-specific mutations using oligonucleotide primers and its application to site-saturation mutagenesis.

Published in:

Molecular Biotechnology, 1996, v. 6, n. 2, p. 179, doi. 10.1007/BF02740772

By:

O'Donohue, Michael;
Geoff Kneale, G.

Publication type:

Article