Works matching Mutagenesis

Results: 5000

Enhancing Catalytic Efficiency of an Actinoplanes utahensis Echinocandin B Deacylase through Random Mutagenesis and Site-Directed Mutagenesis.

Published in:

Applied Biochemistry & Biotechnology, 2020, v. 190, n. 4, p. 1257, doi. 10.1007/s12010-019-03170-3

By:

Cheng, Ying-Nan;
Qiu, Shuai;
Cheng, Feng;
Weng, Chun-Yue;
Wang, Ya-Jun;
Zheng, Yu-Guo

Publication type:

Article

In vivo and in vitro random mutagenesis techniques in plants.

Published in:

EFSA Journal, 2021, v. 19, n. 11, p. 1, doi. 10.2903/j.efsa.2021.6611

By:

Mullins, Ewen;
Bresson, Jean-Louis;
Dalmay, Tamas;
Dewhurst, Ian Crawford;
Epstein, Michelle M.;
Firbank, Leslie George;
Guerche, Philippe;
Hejatko, Jan;
Javier Moreno, Francisco;
Naegeli, Hanspeter;
Nogué, Fabien;
Sánchez Serrano, Jose Juan;
Savoini, Giovanni;
Veromann, Eve;
Veronesi, Fabio;
Casacuberta, Josep;
Lenzi, Paolo;
Munoz Guajardo, Irene;
Raffaello, Tommaso;
Rostoks, Nils

Publication type:

Article

DEVELOPING MUTANT SUNFLOWER LINES (Helianthus annuus L.) THROUGH INDUCED MUTAGENESIS.

Published in:

Helia, 2008, v. 31, n. 48, p. 61, doi. 10.2298/HEL0848061E

By:

Encheva, J.;
Shindrova, P.;
Penchev, E.

Publication type:

Article

IMPROVING THE CHITINOLYTIC ACTIVITY OF STREPTOMYCES GRISEORUBENS E44G BY MUTAGENESIS.

Published in:

Journal of Microbiology, Biotechnology & Food Sciences, 2019, v. 8, n. 5, p. 1156, doi. 10.15414/jmbfs.2019.8.5.1156-1160

By:

Hafez, Elsayed Elsayed;
Rashad, Younes Mohamed;
Abdulkhair, Waleed Mohamed;
Al-Askar, Abdulaziz Abdulrahman;
Ghoneem, Khalid Mohamed;
Baka, Zakaria Awad;
Shabana, Yasser Mohamed

Publication type:

Article

Hyper-production and Characterization of Exoglucanase Through Physical, Chemical, and Combined Mutagenesis in Indigenous Strain of Thermophilic Aspergillus fumigatus.

Published in:

Applied Biochemistry & Biotechnology, 2025, v. 197, n. 6, p. 4002, doi. 10.1007/s12010-025-05222-3

By:

Ishaq, Rabia;
Zafar, Muddassar;
Anwar, Zahid;
Dildar, Iqra;
Mustafa, Ghazala;
Tariq, Tuba;
Ghorbanpour, Mansour;
Hassan, Murtaza

Publication type:

Article

Mutagenesis and breeding of Candida utilis for high-yielding bacterial protein.

Published in:

Feed Research, 2022, v. 45, n. 19, p. 78, doi. 10.13557/j.cnki.issn1002-2813.2022.19.016

By:

YU Jing;
CUI Jin-na;
HU Jian-hua;
LIU Zhan-ying

Publication type:

Article

A Single Active-Site Mutagenesis Confers Enhanced Activity and/or Changed Product Distribution to a Pentalenene Synthase from Streptomyces sp. PSKA01.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 3, p. 392, doi. 10.3390/bioengineering10030392

By:

Liu, Hongshuang;
Fang, Senbiao;
Zhao, Lin;
Men, Xiao;
Zhang, Haibo

Publication type:

Article

Ethyl Methane Sulfonate and Sodium Azide-Mediated Chemical and X-ray-Mediated Physical Mutagenesis Positively Regulate Peroxidase 1 Gene Activity and Biosynthesis of Antineoplastic Vinblastine in Catharanthus roseus.

Published in:

Plants (2223-7747), 2022, v. 11, n. 21, p. 2885, doi. 10.3390/plants11212885

By:

Mistry, Vyoma;
Tiwari, Pragya;
Patel, Paresh;
Vishwakarma, Gajendra Singh;
Lee, Geung-Joo;
Sharma, Abhishek

Publication type:

Article

Improving the temperature characteristics and catalytic efficiency of a mesophilic xylanase from Aspergillus oryzae, AoXyn11A, by iterative mutagenesis based on in silico design.

Published in:

AMB Express, 2017, v. 7, n. 1, p. 1, doi. 10.1186/s13568-017-0399-9

By:

Li, Xue-Qing;
Wu, Qin;
Hu, Die;
Wang, Rui;
Liu, Yan;
Wu, Min-Chen;
Li, Jian-Fang

Publication type:

Article

Site-directed mutagenesis studies of hydrophobic residues in the lid region of T1 lipase.

Published in:

European Journal of Lipid Science & Technology, 2017, v. 119, n. 3, p. n/a, doi. 10.1002/ejlt.201600107

By:

Tang, Qingyun;
Lan, Dongming;
Yang, Bo;
Khan, Faez Iqbal;
Wang, Yonghua

Publication type:

Article

Determination of absorption dose in chemical mutagenesis in plants.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210596

By:

Ke, Changjiao;
Guan, Wenxiang;
Bu, Suhong;
Li, Xiaoxu;
Deng, Yun;
Wei, Zhinan;
Wu, Weiren;
Zheng, Yan

Publication type:

Article

Computational alanine scanning mutagenesis—An improved methodological approach.

Published in:

Journal of Computational Chemistry, 2007, v. 28, n. 3, p. 644, doi. 10.1002/jcc.20566

By:

Moreira, Irina S.;
Fernandes, Pedro A.;
Ramos, Maria J.

Publication type:

Article

Improving Rutin Biotransformation Efficiency of α-L-Rhamnosidase from Bacteroides thetaiotaomicron VPI-5482 via Targeted Mutagenesis Focused on General Acid Motif.

Published in:

Catalysts (2073-4344), 2024, v. 14, n. 8, p. 501, doi. 10.3390/catal14080501

By:

Li, Bin-Chun;
Li, Xue;
Peng, Bo;
Wu, Bingbing;
Li, Xinfeng;
Ding, Guo-Bin

Publication type:

Article

Improving the Thermostability of Glutamate Decarboxylase from Lactobacillus brevis by Consensus Mutagenesis.

Published in:

Applied Biochemistry & Biotechnology, 2020, v. 191, n. 4, p. 1456, doi. 10.1007/s12010-020-03283-0

By:

Hua, Yujiao;
Lyu, Changjiang;
Liu, Chunyan;
Wang, Hongpeng;
Hu, Sheng;
Zhao, Weirui;
Mei, Jiaqi;
Huang, Jun;
Mei, Lehe

Publication type:

Article

Mutagenesis for Improvement of Activity and Stability of Prolyl Aminopeptidase from Aspergillus oryzae.

Published in:

Applied Biochemistry & Biotechnology, 2020, v. 191, n. 4, p. 1483, doi. 10.1007/s12010-020-03277-y

By:

Liu, Dehua;
Zhang, Dawei;
Huang, Qinqin;
Gu, Lili;
Zhou, Nandi;
Tian, Yaping

Publication type:

Article

An Efficient Approach for Two Distal Point Site-Directed Mutagenesis from Randomly Ligated PCR Products.

Published in:

Applied Biochemistry & Biotechnology, 2019, v. 189, n. 4, p. 1318, doi. 10.1007/s12010-019-03059-1

By:

Khezri, Jafar;
Yakhchali, Bagher;
Karkhane, Ali Asghar;
Sangtarash, Mohammad Hossein

Publication type:

Article

Induced Genetic Variation in Crop Plants by Random or Targeted Mutagenesis: Convergence and Differences.

Published in:

Frontiers in Plant Science, 2019, v. 10, p. 1, doi. 10.3389/fpls.2019.01468

By:

Holme, Inger B.;
Gregersen, Per L.;
Brinch-Pedersen, Henrik

Publication type:

Article

Broad Purpose Vector for Site-Directed Insertional Mutagenesis in Bifidobacterium breve.

Published in:

Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2021.636822

By:

Hoedt, Emily C.;
Bottacini, Francesca;
Cash, Nora;
Bongers, Roger S.;
van Limpt, Kees;
Ben Amor, Kaouther;
Knol, Jan;
MacSharry, John;
van Sinderen, Douwe

Publication type:

Article

Effect of episomally encoded DNA polymerases on chemically induced mutagenesis at the hisG46 target in Ames test.

Published in:

Genes & Environment, 2020, v. 42, n. 1, p. 1, doi. 10.1186/s41021-020-00154-2

By:

Grúz, Petr;
Shimizu, Masatomi;
Sugiyama, Kei-ichi;
Yamada, Masami;
Honma, Masamitsu

Publication type:

Article

Engineering of Alicyclobacillus hesperidum l-Arabinose Isomerase for Improved Catalytic Activity and Reduced pH Optimum Using Random and Site-Directed Mutagenesis.

Published in:

Applied Biochemistry & Biotechnology, 2015, v. 177, n. 7, p. 1480, doi. 10.1007/s12010-015-1828-3

By:

Fan, Chen;
Xu, Wei;
Zhang, Tao;
Zhou, Leon;
Jiang, Bo;
Mu, Wanmeng

Publication type:

Article

Asymmetric overlap extension PCR method bypassing intermediate purification and the amplification of wild-type template in site-directed mutagenesis.

Published in:

Biotechnology Letters, 2007, v. 29, n. 6, p. 925, doi. 10.1007/s10529-007-9327-4

By:

Xiao, Yue-Hua;
Yin, Meng-Hui;
Hou, Lei;
Luo, Ming;
Pei, Yan

Publication type:

Article

The mutagenesis moonshot: The propitious beginnings of the environmental mutagenesis and genomics society.

Published in:

Environmental & Molecular Mutagenesis, 2020, v. 61, n. 1, p. 8, doi. 10.1002/em.22313

By:

DeMarini, David M.

Publication type:

Article

Protein–protein recognition: a computational mutagenesis study of the MDM2–P53 complex.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2008, v. 120, n. 4-6, p. 533, doi. 10.1007/s00214-008-0432-9

By:

Moreira, Irina S.;
Fernandes, Pedro A.;
Ramos, Maria J.

Publication type:

Article

Unravelling Hot Spots: a comprehensive computational mutagenesis study.

Published in:

Theoretical Chemistry Accounts: Theory, Computation, & Modeling, 2007, v. 117, n. 1, p. 99, doi. 10.1007/s00214-006-0151-z

By:

Moreira, Irina;
Fernandes, Pedro;
Ramos, Maria

Publication type:

Article

近五年灵芝物理诱变育种研究进展.

Published in:

Acta Edulis Fungi, 2023, v. 30, n. 3, p. 103, doi. 10.16488/j.cnki.1005-9873.2023.03.011

By:

张锦绣;
唐传红;
谭贻;
冯杰;
刘艳芳;
张赫男;
张劲松

Publication type:

Article

Identification and iterative combinatorial mutagenesis of a new naringinase‐producing strain, Aspergillus tubingensis MN589840.

Published in:

Letters in Applied Microbiology, 2021, v. 72, n. 2, p. 141, doi. 10.1111/lam.13379

By:

Xia, X.‐K.;
Zhang, Y.‐E.;
Lei, S.‐J.;
Hu, B.;
Fu, C.‐X.

Publication type:

Article

Mutagenesis of Catalytic Nucleophile of β‐Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase.

Published in:

ChemCatChem, 2021, v. 13, n. 21, p. 4532, doi. 10.1002/cctc.202101107

By:

Hovorková, Michaela;
Kulik, Natalia;
Konvalinková, Dorota;
Petrásková, Lucie;
Křen, Vladimír;
Bojarová, Pavla

Publication type:

Article

Cover Feature: Mutagenesis of Catalytic Nucleophile of β‐Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase (ChemCatChem 21/2021).

Published in:

ChemCatChem, 2021, v. 13, n. 21, p. 4456, doi. 10.1002/cctc.202101515

By:

Hovorková, Michaela;
Kulik, Natalia;
Konvalinková, Dorota;
Petrásková, Lucie;
Křen, Vladimír;
Bojarová, Pavla

Publication type:

Article

Construction of a horseradish peroxidase resistant toward hydrogen peroxide by saturation mutagenesis.

Published in:

Biotechnology & Applied Biochemistry, 2016, v. 63, n. 6, p. 789, doi. 10.1002/bab.1437

By:

Asad, Sedigheh;
Dastgheib, Seyed Mohammad Mehdi;
Khajeh, Khosro

Publication type:

Article

Site-Directed Mutagenesis in Viral Glycoprotein and Its Role in Viral Diagnostics and Therapy.

Published in:

Journal of King Abdulaziz University: Medical Sciences, 2024, v. 31, n. 2, p. 63, doi. 10.4197/Med.31-2.6

By:

Jawa, Basem A.;
Alhazmi, Khulud A.;
Shaikh, Majed M.;
Albulushi, Marwan A.;
Alkhozaee, Mohammad M.;
Almalki, Daee M.;
Filfilan, Weam M.;
Falemban, Afnan H.;
Alqurashi, Eman N.;
Hijazi, Alaa A.;
Alnafeai, Mohammed A.;
Hawsawi, Rami A.;
Bakkawi, Waheed M.;
Kheyami, Mazin M.;
Alzahrani, Ibrahim R.

Publication type:

Article

Screening of α-amino acid ester acyl transferase variant with improved activity by combining rational and random mutagenesis.

Published in:

Journal of Biochemistry, 2023, v. 173, n. 1, p. 43, doi. 10.1093/jb/mvac083

By:

Abe, Isao;
Tagami, Uno;
Kashiwagi, Tatsuki;
Sugiyama, Masakazu;
Suzuki, Shun-ichi;
Takagi, Hiroshi;
Yokozeki, Kenzo

Publication type:

Article

Induced genetic diversity through mutagenesis in wheat gene pool and significant use of SCoT markers to underpin key agronomic traits.

Published in:

BMC Plant Biology, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12870-024-05345-5

By:

Abdelhameed, Ahmed Ali;
Ali, Mohammed;
Darwish, Doaa Bahaa Eldin;
AlShaqhaa, Manal Abdullah;
Selim, Dalia Abdel-Fattah H.;
Nagah, Aziza;
Zayed, Muhammad

Publication type:

Article

New approach for fish breeding by chemical mutagenesis: establishment of TILLING method in fugu (Takifugu rubripes) with ENU mutagenesis.

Published in:

BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-786

By:

Miwa Kuroyanagi;
Takashi Katayama;
Tadashi Imai;
Yoshihisa Yamamoto;
Shin-ichi Chisada;
Yasutoshi Yoshiura;
Tomokazu Ushijima;
Tomonao Matsushita;
Masashi Fujita;
Aoi Nozawa;
Yuzuru Suzuki;
Kiyoshi Kikuchi;
Hiroyuki Okamoto

Publication type:

Article

Perspective on Mutagenesis and Repair: The Standard Model and Alternate Modes of Mutagenesis.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2005, v. 40, n. 3, p. 155, doi. 10.1080/10409230590954153

By:

Miller, Jeffrey H.

Publication type:

Article

OBTAINING CANDIDATE SALT TOLERANT WHEAT MUTANT LINES DERIVED FROM COMBINATION OF SODIUM AZIDE MUTAGENESIS AND SOMATIC EMBRYOGENESIS.

Published in:

Trakya University Journal of Natural Sciences, 2019, v. 20, n. 2, p. 129, doi. 10.23902/trkjnat.571255

By:

SEN, Ayse;
SARSU2, Fatma

Publication type:

Article

Improving Geldanamycin Production in Streptomyces geldanamycininus Through UV Mutagenesis of Protoplast.

Published in:

Microorganisms, 2025, v. 13, n. 1, p. 186, doi. 10.3390/microorganisms13010186

By:

Yuan, Yuan;
Yang, Lu;
Fang, Zhikai;
Chen, Haimin;
Sun, Fei;
Jiang, Hong;
Zhou, Jian

Publication type:

Article

Multiple-site fragment deletion, insertion and substitution mutagenesis by modified overlap extension PCR.

Published in:

Biotechnology & Biotechnological Equipment, 2017, v. 31, n. 2, p. 339, doi. 10.1080/13102818.2017.1279033

By:

Zeng, Fanli;
Zhang, Yujie;
Zhang, Ze;
Malik, Asrar Ahmad;
Lin, Yibin

Publication type:

Article

Selection of IgG variants with increased FcRn binding using random and directed mutagenesis: impact on effector functions.

Published in:

Frontiers in Immunology, 2015, v. 6, p. 1, doi. 10.3389/fimmu.2015.00039

By:

Monnet, Céline;
Jorieux, Sylvie;
Fournier, Nathalie;
De Romeuf, Christophe;
Fontayne, Alexandre;
Mondon, Philippe;
Urbain, Rémi;
Behrens, Christian K.;
Bouayadi, Khalil

Publication type:

Article

Site-Directed Mutagenesis to Improve Sensitivity of a Synthetic Two-Component Signaling System.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147494

By:

Olshefsky, Audrey;
Shehata, Laila;
Kuldell, Natalie

Publication type:

Article

Enhancement of cyanobacterial PHB production using random chemical mutagenesis with detection through FACS.

Published in:

Bioprocess & Biosystems Engineering, 2023, v. 46, n. 2, p. 297, doi. 10.1007/s00449-022-02834-5

By:

Price, Shawn;
Kuzhiumparambil, Unnikrishnan;
Pernice, Mathieu;
Herdean, Andrei;
Ralph, Peter

Publication type:

Article

A single digestion, single-stranded oligonucleotide mediated PCR-independent site-directed mutagenesis method.

Published in:

Applied Microbiology & Biotechnology, 2020, v. 104, n. 9, p. 3993, doi. 10.1007/s00253-020-10477-3

By:

Dong, Mengjie;
Wang, Fei;
Li, Qingqing;
Han, Rui;
Li, Aitao;
Zhai, Chao;
Ma, Lixin

Publication type:

Article

紫外-亚硝酸钠复合诱变高产纤维素酶菌株.

Published in:

China Brewing, 2020, v. 39, n. 8, p. 97, doi. 10.11882/j.issn.0254-5071.2020.08.019

By:

左勇;
何颂捷;
秦世蓉;
杨建飞;
徐佳;
黄雪芹;
陈静;
宋华

Publication type:

Article

From Chemical Mutagenesis to Post-Expression Mutagenesis: A 50 Year Odyssey.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 20, p. 5896, doi. 10.1002/anie.201509310

By:

Wright, Tom H.;
Vallée, M. Robert J.;
Davis, Benjamin G.

Publication type:

Article

Cloning and characterization of an acyl-CoA-dependent diacylglycerol acyltransferase 1 ( DGAT1) gene from Tropaeolum majus, and a study of the functional motifs of the DGAT protein using site-directed mutagenesis to modify enzyme activity and oil content.

Published in:

Plant Biotechnology Journal, 2008, v. 6, n. 8, p. 799, doi. 10.1111/j.1467-7652.2008.00358.x

By:

Xu, Jingyu;
Francis, Tammy;
Mietkiewska, Elzbieta;
Giblin, E. Michael;
Barton, Dennis L.;
Zhang, Yan;
Zhang, Meng;
Taylor, David C.

Publication type:

Article

Site-directed mutagenesis identified the key active site residues of 2,3-oxidosqualene cyclase HcOSC6 responsible for cucurbitacins biosynthesis in Hemsleya chinensis.

Published in:

Frontiers in Plant Science, 2023, v. 14, p. 1, doi. 10.3389/fpls.2023.1138893

By:

Xia Li;
Geng Chen;
Qing-Qing Gao;
Chun-Fan Xiang;
Cheng-Xiao Yuan;
Xiao-Ning Li;
Yan-Yu Shu;
Guang-Hui Zhang;
Yan-Li Liang;
Sheng-Chao Yang;
Chen-Xi Zhai;
Yan Zhao

Publication type:

Article

Optimized methods for random and targeted mutagenesis in field pea (Pisum sativum L.).

Published in:

Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.995542

By:

Pandey, Prashant Kumar;
Bhowmik, Pankaj;
Kagale, Sateesh

Publication type:

Article

Comprehensive Review of Mutagenesis Techniques and Their pharmaceutical Applications.

Published in:

Degrés, 2024, v. 9, n. 12, p. 148

By:

Sawarkar, Hemant Arunrao;
Sheikh, Aijaz A.;
Thakare, Balaji N.

Publication type:

Article

Systems Biology-Based Investigation of Cellular Antiviral Drug Targets Identified by Gene-Trap Insertional Mutagenesis.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 9, p. 1, doi. 10.1371/journal.pcbi.1005074

By:

Cheng, Feixiong;
Murray, James L.;
Zhao, Junfei;
Sheng, Jinsong;
Zhao, Zhongming;
Rubin, Donald H.

Publication type:

Article

海洋产尿酸氧化酶菌株的诱变选育及发酵优化.

Published in:

China Food Additives, 2025, v. 36, n. 6-8, p. 65, doi. 10.19804/j.issn1006-2513.2025.6.009

By:

王聪;
迟雪梅;
于爽;
孙溪;
郭信志;
魏振勇;
张庆芳;
迟乃玉

Publication type:

Article

Mutagenesis Targeting the S 153 Residue Within the Transmembrane β-Hairpin of Mosquito-Larvicidal Mpp46Ab Affects Its Toxicity and the Synergistic Toxicity with Cry4Aa.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 489, doi. 10.3390/biology14050489

By:

Hayakawa, Tohru;
Yamaoka, Syun;
Asakura, Mami;
Hirano, Minako;
Ide, Toru

Publication type:

Article