Works matching Motor neurons

Results: 5000

Supraphysiological expression of survival motor neuron protein from an adenovirus vector does not adversely affect cell function.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 4, p. 252, doi. 10.1139/bcb-2012-0094

By:

Goulet, Benoit B.;
McFall, Emily R.;
Wong, Carmen M.;
Kothary, Rashmi;
Parks, Robin J.

Publication type:

Article

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.

Published in:

PLoS Genetics, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pgen.1006680

By:

Kline, Rachel A.;
Kaifer, Kevin A.;
Osman, Erkan Y.;
Carella, Francesco;
Tiberi, Ariana;
Ross, Jolill;
Pennetta, Giuseppa;
Lorson, Christian L.;
Murray, Lyndsay M.

Publication type:

Article

Motor Band Sign in Motor Neuron Disease: A Marker for Upper Motor Neuron Involvement.

Published in:

Canadian Journal of Neurological Sciences, 2023, v. 50, n. 3, p. 373, doi. 10.1017/cjn.2022.52

By:

Chung, Hee Sahng;
Melkus, Gerd;
Bourque, Pierre;
Chakraborty, Santanu

Publication type:

Article

Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy.

Published in:

Journal of Anatomy, 2016, v. 228, n. 3, p. 443, doi. 10.1111/joa.12419

By:

Powis, Rachael A.;
Gillingwater, Thomas H.

Publication type:

Article

Superconditioning TMS for examining upper motor neuron function in MND.

Published in:

Experimental Brain Research, 2019, v. 237, n. 8, p. 2087, doi. 10.1007/s00221-019-05573-4

By:

Calancie, Blair;
Young, Eufrosina;
Watson, Mary Lou;
Wang, Dongliang;
Alexeeva, Natalia

Publication type:

Article

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 545, doi. 10.3390/cells12040545

By:

Castellanos-Montiel, María José;
Chaineau, Mathilde;
Franco-Flores, Anna Kristyna;
Haghi, Ghazal;
Carrillo-Valenzuela, Dulce;
Reintsch, Wolfgang E.;
Chen, Carol X.-Q.;
Durcan, Thomas M.

Publication type:

Article

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1127, doi. 10.3390/cells10051127

By:

Cutarelli, Alessandro;
Martínez-Rojas, Vladimir A.;
Tata, Alice;
Battistella, Ingrid;
Rossi, Daniela;
Arosio, Daniele;
Musio, Carlo;
Conti, Luciano;
Pession, Andrea

Publication type:

Article

Highly Efficient Conversion of Motor Neuron-Like NSC-34 Cells into Functional Motor Neurons by Prostaglandin E2.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1741, doi. 10.3390/cells9071741

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Sato, Masaki;
Shibukawa, Yoshiyuki;
Aono, Yuri;
Saigusa, Tadashi;
Ito, Yoshihisa;
Ishige, Kumiko

Publication type:

Article

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 502, doi. 10.3390/cells9020502

By:

Genc, Baris;
Gozutok, Oge;
Kocak, Nuran;
Ozdinler, P. Hande

Publication type:

Article

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.

Published in:

Cells (2073-4409), 2019, v. 8, n. 6, p. 581, doi. 10.3390/cells8060581

By:

Bax, Monique;
McKenna, Jessie;
Do-Ha, Dzung;
Stevens, Claire H.;
Higginbottom, Sarah;
Balez, Rachelle;
Cabral-da-Silva, Mauricio e Castro;
Farrawell, Natalie E.;
Engel, Martin;
Poronnik, Philip;
Yerbury, Justin J.;
Saunders, Darren N.;
Ooi, Lezanne

Publication type:

Article

Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study.

Published in:

Brain Pathology, 2025, v. 35, n. 1, p. 1, doi. 10.1111/bpa.13286

By:

Murakami, Aya;
Koga, Shunsuke;
Fujioka, Shinsuke;
White, Adrianna E.;
Bieniek, Kevin F.;
Sekiya, Hiroaki;
DeJesus‐Hernandez, Mariely;
Finch, NiCole A.;
van Blitterswijk, Marka;
Nakamura, Masataka;
Tsuboi, Yoshio;
Murray, Melissa E.;
Wszolek, Zbigniew K.;
Dickson, Dennis W.

Publication type:

Article

Spinal Cord Organoids to Study Motor Neuron Development and Disease.

Published in:

Life (2075-1729), 2023, v. 13, n. 6, p. 1254, doi. 10.3390/life13061254

By:

Buchner, Felix;
Dokuzluoglu, Zeynep;
Grass, Tobias;
Rodriguez-Muela, Natalia

Publication type:

Article

Mills syndrome as a rare and significant motor neuron disease: a case report.

Published in:

2025

By:

Onder, Ozlem;
Isik, Sahin

Publication type:

Case Study

Role of EphA4 in Mediating Motor Neuron Death in MND.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9430, doi. 10.3390/ijms22179430

By:

Zhao, Jing;
Stevens, Claire H.;
Boyd, Andrew W.;
Ooi, Lezanne;
Bartlett, Perry F.

Publication type:

Article

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 4, p. 509, doi. 10.1007/s00401-011-0797-z

By:

Geser, Felix;
Stein, Beth;
Partain, Michael;
Elman, Lauren B.;
McCluskey, Leo F.;
Xie, Sharon X.;
Van Deerlin, Vivianna M.;
Kwong, Linda K.;
Lee, Virginia M.-Y.;
Trojanowski, John Q.

Publication type:

Article

PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells.

Published in:

Iranian Journal of Basic Medical Sciences, 2020, v. 23, n. 4, p. 431, doi. 10.22038/ijbms.2020.39797.9434

By:

Darvishi, Marzieh;
Hamidabadi, Hatef Ghasemi;
Negah, Sajad Sahab;
Moayeri, Ardeshir;
Tiraihi, Taki;
Mirnajafi-Zadeh, Javad;
Jahan-Abad, Ali Jahanbazi;
Shojaei, Amir

Publication type:

Article

Beta-band intermuscular coherence: a novel biomarker of upper motor neuron dysfunction in motor neuron disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2849, doi. 10.1093/brain/aws150

By:

Fisher, Karen M.;
Zaaimi, Boubker;
Williams, Timothy L.;
Baker, Stuart N.;
Baker, Mark R.

Publication type:

Article

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0806-3

By:

Rehorst, Wiebke A.;
Thelen, Maximilian P.;
Nolte, Hendrik;
Türk, Clara;
Cirak, Sebahattin;
Peterson, Jonathan M.;
Wong, G. William;
Wirth, Brunhilde;
Krüger, Marcus;
Winter, Dominic;
Kye, Min Jeong

Publication type:

Article

Homozygous Survival Motor Neuron 2 Gene Deletion and Sporadic Lower Motor Neuron Disease in Children: Case Report and Literature Review.

Published in:

2013

By:

Liping, Lu;
Hongwei, Ma;
Lin, Wang

Publication type:

Case Study

Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons.

Published in:

Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00058

By:

Tosolini, Andrew Paul;
Mohan, Rahul;
Morris, Renée

Publication type:

Article

Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.578143

By:

Lin, Jianing;
Huang, Pian;
Chen, Weineng;
Ye, Chenghui;
Su, Huanxing;
Yao, Xiaoli

Publication type:

Article

Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2024.1488951

By:

Lewis, Ryan D.;
Keilholz, Amy N.;
Smith, Catherine L.;
Burd, Ethan A.;
Nichols, Nicole L.

Publication type:

Article

Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2024.1488951

By:

Lewis, Ryan D.;
Keilholz, Amy N.;
Smith, Catherine L.;
Burd, Ethan A.;
Nichols, Nicole L.

Publication type:

Article

Corticospinal motor neuron specific transduction of the TARDBP gene via viral vectors.

Published in:

Anatomy: International Journal of Experimental & Clinical Anatomy, 2020, v. 14, p. S156

By:

İlhan, Furkan;
Çorumlu, Elif Polat;
Büyükgüdük, İlkim;
Kapkaç, Handan Açelya;
Arslanyolu, Muhittin;
Ulupmar, Emel

Publication type:

Article

Role of glial cells in motor neuron degeneration in hereditary spastic paraplegias.

Published in:

Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1553658

By:

Vijayaraghavan, Manaswini;
Murali, Sarvika Periyapalayam;
Thakur, Gitika;
Li, Xue-Jun

Publication type:

Article

Synaptic remodeling follows upper motor neuron hyperexcitability in a rodent model of TDP-43.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1274979

By:

Dyer, Marcus S.;
Odierna, G. Lorenzo;
Clark, Rosemary M.;
Woodhouse, Adele;
Blizzard, Catherine A.

Publication type:

Article

Amyotrophic Lateral Sclerosis: A Neurodegenerative Motor Neuron Disease With Ocular Involvement.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.566858

By:

Rojas, Pilar;
Ramírez, Ana I.;
Fernández-Albarral, José A.;
López-Cuenca, Inés;
Salobrar-García, Elena;
Cadena, Manuel;
Elvira-Hurtado, Lorena;
Salazar, Juan J.;
de Hoz, Rosa;
Ramírez, José M.

Publication type:

Article

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 13, p. 3811, doi. 10.1523/JNEUROSCI.2396-15.2016

By:

Fallini, Claudia;
Donlin-Asp, Paul G.;
Rouanet, Jeremy P.;
Bassell, Gary J.;
Rossoll, Wilfried

Publication type:

Article

Duple-MONDNet: duple deep learning-based mobile net for motor neuron disease identification.

Published in:

Turkish Journal of Medical Sciences, 2025, v. 55, n. 1, p. 140, doi. 10.55730/1300-0144.5952

By:

HELEN, Sony;
JAWHAR, Joseph

Publication type:

Article

Sensitive Detection of Motor Neuron Disease Derived Exosomal miRNA Using Electrocatalytic Activity of Gold‐Loaded Superparamagnetic Ferric Oxide Nanocubes.

Published in:

ChemElectroChem, 2020, v. 7, n. 16, p. 3459, doi. 10.1002/celc.202000828

By:

Masud, Mostafa Kamal;
Mahmudunnabi, Rabbee G.;
Aziz, Nahian Binte;
Stevens, Claire H.;
Do‐Ha, Dzung;
Yang, Shu;
Blair, Ian P.;
Hossain, Md. Shahriar A.;
Shim, Yoon‐Bo;
Ooi, Lezanne;
Yamauchi, Yusuke;
Shiddiky, Muhammad J. A.

Publication type:

Article

A review of electrophysiological studies of lower motor neuron involvement in amyotrophic lateral sclerosis.

Published in:

2019

By:

Amin Lari, Ali;
Ghavanini, Amer A.;
Bokaee, Hamid Reza

Publication type:

journal article

CSF Heavy Neurofilament May Discriminate and Predict Motor Neuron Diseases with Upper Motor Neuron Involvement.

Published in:

Biomedicines, 2021, v. 9, n. 11, p. 1623, doi. 10.3390/biomedicines9111623

By:

Simonini, Cecilia;
Zucchi, Elisabetta;
Bedin, Roberta;
Martinelli, Ilaria;
Gianferrari, Giulia;
Fini, Nicola;
Sorarù, Gianni;
Liguori, Rocco;
Vacchiano, Veria;
Mandrioli, Jessica

Publication type:

Article

ERRγ is downregulated in injured motor neuron subpopulations following brachial plexus root avulsion.

Published in:

Experimental & Therapeutic Medicine, 2020, v. 19, n. 1, p. 205, doi. 10.3892/etm.2019.8209

By:

Yu, Guangyin;
Zilundu, Prince Last Mudenda;
Liu, Linlin;
Zhong, Ke;
Tang, Ying;
Ling, Zemin;
Zhou, Li-Hua

Publication type:

Article

Bunina bodies in motor and non-motor neurons revisited: A pathological study of an ALS patient after long-term survival on a respirator.

Published in:

Neuropathology, 2014, v. 34, n. 4, p. 392, doi. 10.1111/neup.12105

By:

Kimura, Tadashi;
Jiang, Haishan;
Konno, Takuya;
Seto, Makiko;
Iwanaga, Keisuke;
Tsujihata, Mitsuhiro;
Satoh, Akira;
Onodera, Osamu;
Kakita, Akiyoshi;
Takahashi, Hitoshi

Publication type:

Article

Elevated NLRP3 Inflammasome Activation Is Associated with Motor Neuron Degeneration in ALS.

Published in:

Cells (2073-4409), 2024, v. 13, n. 12, p. 995, doi. 10.3390/cells13120995

By:

Cihankaya, Hilal;
Bader, Verian;
Winklhofer, Konstanze F.;
Vorgerd, Matthias;
Matschke, Johann;
Stahlke, Sarah;
Theiss, Carsten;
Matschke, Veronika

Publication type:

Article

Altered Metabolism in Motor Neuron Diseases: Mechanism and Potential Therapeutic Target.

Published in:

Cells (2073-4409), 2023, v. 12, n. 11, p. 1536, doi. 10.3390/cells12111536

By:

Barone, Cassandra;
Qi, Xin

Publication type:

Article

Induction of Survival of Motor Neuron (SMN) Protein Deficiency in Spinal Astrocytes by Small Interfering RNA as an In Vitro Model of Spinal Muscular Atrophy.

Published in:

Cells (2073-4409), 2022, v. 11, n. 3, p. 558, doi. 10.3390/cells11030558

By:

Leo, Markus;
Schmitt, Linda-Isabell;
Fleischer, Michael;
Steffen, Rebecca;
Osswald, Cora;
Kleinschnitz, Christoph;
Hagenacker, Tim

Publication type:

Article

Rapid Generation of Ventral Spinal Cord-like Astrocytes from Human iPSCs for Modeling Non-Cell Autonomous Mechanisms of Lower Motor Neuron Disease.

Published in:

Cells (2073-4409), 2022, v. 11, n. 3, p. 399, doi. 10.3390/cells11030399

By:

Soubannier, Vincent;
Chaineau, Mathilde;
Gursu, Lale;
Haghi, Ghazal;
Franco Flores, Anna Kristyna;
Rouleau, Guy;
Durcan, Thomas M.;
Stifani, Stefano

Publication type:

Article

A Step-by-Step Refined Strategy for Highly Efficient Generation of Neural Progenitors and Motor Neurons from Human Pluripotent Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 3087, doi. 10.3390/cells10113087

By:

Ren, Jie;
Li, Chaoyi;
Zhang, Mengfei;
Wang, Huakun;
Xie, Yali;
Tang, Yu

Publication type:

Article

Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion.

Published in:

Cells (2073-4409), 2021, v. 10, n. 7, p. 1614, doi. 10.3390/cells10071614

By:

Zilundu, Prince Last Mudenda;
Xu, Xiaoying;
Liaquat, Zaara;
Wang, Yaqiong;
Zhong, Ke;
Fu, Rao;
Zhou, Lihua

Publication type:

Article

Pathogenic Genome Signatures That Damage Motor Neurons in Amyotrophic Lateral Sclerosis.

Published in:

Cells (2073-4409), 2020, v. 9, n. 12, p. 2687, doi. 10.3390/cells9122687

By:

Yousefian-Jazi, Ali;
Seol, YunHee;
Kim, Jieun;
Ryu, Hannah L.;
Lee, Junghee;
Ryu, Hoon

Publication type:

Article

The Molecular Mechanisms Underlying Prostaglandin D2-Induced Neuritogenesis in Motor Neuron-Like NSC-34 Cells.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 934, doi. 10.3390/cells9040934

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Yoshimura, Nana;
Miyagishi, Hiroko;
Kanazawa, Takanori;
Hashizaki, Kaname;
Suzuki, Toyofumi;
Ishige, Kumiko

Publication type:

Article

Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 7, p. N.PAG, doi. 10.3390/ph15070828

By:

Imran, Saima Jalil;
Vagaska, Barbora;
Kriska, Jan;
Anderova, Miroslava;
Bortolozzi, Mario;
Gerosa, Gino;
Ferretti, Patrizia;
Vrzal, Radim

Publication type:

Article

A homozygous I684T in GLE1 as a novel cause of arthrogryposis and motor neuron loss.

Published in:

Clinical Genetics, 2018, v. 93, n. 1, p. 173, doi. 10.1111/cge.13086

By:

Paakkola, T.;
Vuopala, K.;
Kokkonen, H.;
Ignatius, J.;
Valkama, M.;
Moilanen, J. S.;
Fahiminiya, S.;
Majewski, J.;
Hinttala, R.;
Uusimaa, J.

Publication type:

Article

Neurotrophic factors in the physiology of motor neurons and their role in the pathobiology and therapeutic approach to amyotrophic lateral sclerosis.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1238453

By:

Stansberry, Wesley M.;
Pierchala, Brian A.

Publication type:

Article

Circulating MicroRNAs as Diagnostic Biomarkers for Motor Neuron Disease.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00354

By:

Wang, Lin;
Zhang, Lijuan

Publication type:

Article

Loss of ALS2 Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 33, p. 7567, doi. 10.1523/JNEUROSCI.1645-05.2005

By:

Huaibin Cai;
Xian Lin;
Chengsong Xie;
Laird, Fiona M.;
Chen Lai;
Hongjin Wen;
Hsueh-Cheng Chiang;
Hoon Shim;
Farah, Mohamed H.;
Hoke, Ahmet;
Price, Donald L.;
Wong, Philip C.

Publication type:

Article

The Prevalence and Management of Saliva Problems in Motor Neuron Disease: A 4-Year Analysis of the Scottish Motor Neuron Disease Register.

Published in:

Neurodegenerative Diseases, 2020, v. 20, n. 4, p. 147, doi. 10.1159/000514615

By:

Pearson, Iona;
Glasmacher, Stella A.;
Newton, Judith;
Beswick, Emily;
Mehta, Arpan R.;
Davenport, Richard;
Chandran, Siddharthan;
Pal, Suvankar

Publication type:

Article

Cerebrospinal Fluid Neurofilaments May Discriminate Upper Motor Neuron Syndromes: A Pilot Study.

Published in:

Neurodegenerative Diseases, 2018, v. 18, n. 5/6, p. 255, doi. 10.1159/000493986

By:

Zucchi, Elisabetta;
Bedin, Roberta;
Fasano, Antonio;
Fini, Nicola;
Gessani, Annalisa;
Vinceti, Marco;
Mandrioli, Jessica

Publication type:

Article

Role of Magnetic Resonance Imaging in Diagnosis of Motor Neuron Disease: Literature Review and Two Case Illustrations.

Published in:

Permanente Journal, 2019, v. 23, n. 1, p. 62, doi. 10.7812/TPP/18-131

By:

Sawalha, Khalid;
Gonzalez-Toledo, Eduardo;
Hussein, Omar

Publication type:

Article