Works matching Motor neurons

Results: 5000

Supraphysiological expression of survival motor neuron protein from an adenovirus vector does not adversely affect cell function.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 4, p. 252, doi. 10.1139/bcb-2012-0094

By:

Goulet, Benoit B.;
McFall, Emily R.;
Wong, Carmen M.;
Kothary, Rashmi;
Parks, Robin J.

Publication type:

Article

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.

Published in:

PLoS Genetics, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pgen.1006680

By:

Kline, Rachel A.;
Kaifer, Kevin A.;
Osman, Erkan Y.;
Carella, Francesco;
Tiberi, Ariana;
Ross, Jolill;
Pennetta, Giuseppa;
Lorson, Christian L.;
Murray, Lyndsay M.

Publication type:

Article

Motor Band Sign in Motor Neuron Disease: A Marker for Upper Motor Neuron Involvement.

Published in:

Canadian Journal of Neurological Sciences, 2023, v. 50, n. 3, p. 373, doi. 10.1017/cjn.2022.52

By:

Chung, Hee Sahng;
Melkus, Gerd;
Bourque, Pierre;
Chakraborty, Santanu

Publication type:

Article

Mills syndrome as a rare and significant motor neuron disease: a case report.

Published in:

2025

By:

Onder, Ozlem;
Isik, Sahin

Publication type:

Case Study

Superconditioning TMS for examining upper motor neuron function in MND.

Published in:

Experimental Brain Research, 2019, v. 237, n. 8, p. 2087, doi. 10.1007/s00221-019-05573-4

By:

Calancie, Blair;
Young, Eufrosina;
Watson, Mary Lou;
Wang, Dongliang;
Alexeeva, Natalia

Publication type:

Article

Spinal Cord Organoids to Study Motor Neuron Development and Disease.

Published in:

Life (2075-1729), 2023, v. 13, n. 6, p. 1254, doi. 10.3390/life13061254

By:

Buchner, Felix;
Dokuzluoglu, Zeynep;
Grass, Tobias;
Rodriguez-Muela, Natalia

Publication type:

Article

Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study.

Published in:

Brain Pathology, 2025, v. 35, n. 1, p. 1, doi. 10.1111/bpa.13286

By:

Murakami, Aya;
Koga, Shunsuke;
Fujioka, Shinsuke;
White, Adrianna E.;
Bieniek, Kevin F.;
Sekiya, Hiroaki;
DeJesus‐Hernandez, Mariely;
Finch, NiCole A.;
van Blitterswijk, Marka;
Nakamura, Masataka;
Tsuboi, Yoshio;
Murray, Melissa E.;
Wszolek, Zbigniew K.;
Dickson, Dennis W.

Publication type:

Article

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 4, p. 509, doi. 10.1007/s00401-011-0797-z

By:

Geser, Felix;
Stein, Beth;
Partain, Michael;
Elman, Lauren B.;
McCluskey, Leo F.;
Xie, Sharon X.;
Van Deerlin, Vivianna M.;
Kwong, Linda K.;
Lee, Virginia M.-Y.;
Trojanowski, John Q.

Publication type:

Article

Highly Efficient Conversion of Motor Neuron-Like NSC-34 Cells into Functional Motor Neurons by Prostaglandin E2.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1741, doi. 10.3390/cells9071741

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Sato, Masaki;
Shibukawa, Yoshiyuki;
Aono, Yuri;
Saigusa, Tadashi;
Ito, Yoshihisa;
Ishige, Kumiko

Publication type:

Article

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 502, doi. 10.3390/cells9020502

By:

Genc, Baris;
Gozutok, Oge;
Kocak, Nuran;
Ozdinler, P. Hande

Publication type:

Article

Beta-band intermuscular coherence: a novel biomarker of upper motor neuron dysfunction in motor neuron disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2849, doi. 10.1093/brain/aws150

By:

Fisher, Karen M.;
Zaaimi, Boubker;
Williams, Timothy L.;
Baker, Stuart N.;
Baker, Mark R.

Publication type:

Article

Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons.

Published in:

Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00058

By:

Tosolini, Andrew Paul;
Mohan, Rahul;
Morris, Renée

Publication type:

Article

PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells.

Published in:

Iranian Journal of Basic Medical Sciences, 2020, v. 23, n. 4, p. 431, doi. 10.22038/ijbms.2020.39797.9434

By:

Darvishi, Marzieh;
Hamidabadi, Hatef Ghasemi;
Negah, Sajad Sahab;
Moayeri, Ardeshir;
Tiraihi, Taki;
Mirnajafi-Zadeh, Javad;
Jahan-Abad, Ali Jahanbazi;
Shojaei, Amir

Publication type:

Article

Homozygous Survival Motor Neuron 2 Gene Deletion and Sporadic Lower Motor Neuron Disease in Children: Case Report and Literature Review.

Published in:

2013

By:

Liping, Lu;
Hongwei, Ma;
Lin, Wang

Publication type:

Case Study

Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy.

Published in:

Journal of Anatomy, 2016, v. 228, n. 3, p. 443, doi. 10.1111/joa.12419

By:

Powis, Rachael A.;
Gillingwater, Thomas H.

Publication type:

Article

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 545, doi. 10.3390/cells12040545

By:

Castellanos-Montiel, María José;
Chaineau, Mathilde;
Franco-Flores, Anna Kristyna;
Haghi, Ghazal;
Carrillo-Valenzuela, Dulce;
Reintsch, Wolfgang E.;
Chen, Carol X.-Q.;
Durcan, Thomas M.

Publication type:

Article

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1127, doi. 10.3390/cells10051127

By:

Cutarelli, Alessandro;
Martínez-Rojas, Vladimir A.;
Tata, Alice;
Battistella, Ingrid;
Rossi, Daniela;
Arosio, Daniele;
Musio, Carlo;
Conti, Luciano;
Pession, Andrea

Publication type:

Article

Role of EphA4 in Mediating Motor Neuron Death in MND.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9430, doi. 10.3390/ijms22179430

By:

Zhao, Jing;
Stevens, Claire H.;
Boyd, Andrew W.;
Ooi, Lezanne;
Bartlett, Perry F.

Publication type:

Article

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0806-3

By:

Rehorst, Wiebke A.;
Thelen, Maximilian P.;
Nolte, Hendrik;
Türk, Clara;
Cirak, Sebahattin;
Peterson, Jonathan M.;
Wong, G. William;
Wirth, Brunhilde;
Krüger, Marcus;
Winter, Dominic;
Kye, Min Jeong

Publication type:

Article

Genetic Basis of Motor Neuron Diseases: Insights, Clinical Management, and Future Directions.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4904, doi. 10.3390/ijms26104904

By:

Antonakoudis, Apostolos;
Kyriakoudi, Stella Aikaterini;
Chatzi, Despoina;
Dermitzakis, Iasonas;
Gargani, Sofia;
Meditskou, Soultana;
Manthou, Maria Eleni;
Theotokis, Paschalis

Publication type:

Article

Motor neuron disease beginning with frontotemporal dementia: clinical features and progression.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2021, v. 22, n. 7/8, p. 508, doi. 10.1080/21678421.2021.1910309

By:

Gromicho, Marta;
Kuzma-Kozakiewicz, Magdalena;
Szacka, Katarzyna;
Nieporecki, Krzysztof;
Andersen, Peter M.;
Grosskreutz, Julian;
Petri, Susanne;
Pinto, Susana;
Uysal, Hilmi;
Swash, Michael;
De Carvalho, Mamede

Publication type:

Article

Patterns of symptom development in patients with motor neuron disease.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2018, v. 19, n. 1/2, p. 21, doi. 10.1080/21678421.2017.1386688

By:

Walhout, Renée;
Verstraete, Esther;
van den Heuvel, Martijn P.;
Veldink, Jan H.;
van den Berg, Leonard H.

Publication type:

Article

Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2024.1488951

By:

Lewis, Ryan D.;
Keilholz, Amy N.;
Smith, Catherine L.;
Burd, Ethan A.;
Nichols, Nicole L.

Publication type:

Article

Spinal TNF-α receptor 1 is differentially required for phrenic long-term facilitation (pLTF) over the course of motor neuron death in adult rats.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2024.1488951

By:

Lewis, Ryan D.;
Keilholz, Amy N.;
Smith, Catherine L.;
Burd, Ethan A.;
Nichols, Nicole L.

Publication type:

Article

The impact of upper motor neuron involvement on clinical features, disease progression and prognosis in amyotrophic lateral sclerosis.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1249429

By:

Colombo, Eleonora;
Gentile, Francesco;
Maranzano, Alessio;
Doretti, Alberto;
Verde, Federico;
Olivero, Marco;
Gagliardi, Delia;
Faré, Matteo;
Meneri, Megi;
Poletti, Barbara;
Maderna, Luca;
Corti, Stefania;
Corbo, Massimo;
Morelli, Claudia;
Silani, Vincenzo;
Ticozzi, Nicola

Publication type:

Article

Nonalcoholic Fatty Liver Disease in Patients with Inherited and Sporadic Motor Neuron Degeneration.

Published in:

Genes, 2022, v. 13, n. 6, p. 936, doi. 10.3390/genes13060936

By:

Johnson, Brian;
Kokkinis, Angela;
Gai, Neville;
Shamim, Ejaz A.;
Blackstone, Craig;
Fischbeck, Kenneth H.;
Grunseich, Christopher

Publication type:

Article

A Novel Variant in Superoxide Dismutase 1 Gene (p.V119M) in Als Patients with Pure Lower Motor Neuron Presentation.

Published in:

Genes, 2021, v. 12, n. 10, p. 1544, doi. 10.3390/genes12101544

By:

Ricci, Claudia;
Giannini, Fabio;
Riolo, Giulia;
Bocci, Silvia;
Casali, Stefania;
Battistini, Stefania

Publication type:

Article

Subacute combined degeneration of the spinal cord masking motor neuron disease: a case report.

Published in:

2019

By:

Loveland, Paula;
Wong, Aaron;
Vivekanandam, Vinojini;
Lim, Wen Kwang

Publication type:

journal article

Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells.

Published in:

Molecular Brain, 2015, v. 8, p. 1, doi. 10.1186/s13041-015-0172-4

By:

Shimojo, Daisuke;
Onodera, Kazunari;
Doi-Torii, Yukiko;
Ishihara, Yasuharu;
Hattori, Chinatsu;
Miwa, Yukino;
Tanaka, Satoshi;
Okada, Rina;
Ohyama, Manabu;
Shoji, Masanobu;
Nakanishi, Atsushi;
Doyu, Manabu;
Okano, Hideyuki;
Okada, Yohei

Publication type:

Article

Measurement of spinal cord atrophy using phase sensitive inversion recovery (PSIR) imaging in motor neuron disease.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0208255

By:

Olney, Nicholas T.;
Bischof, Antje;
Rosen, Howard;
Caverzasi, Eduardo;
Stern, William A.;
Lomen-Hoerth, Catherine;
Miller, Bruce L.;
Henry, Roland G.;
Papinutto, Nico

Publication type:

Article

Erythropoietin attenuates motor neuron programmed cell death in a burn animal model.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190039

By:

Wu, Sheng-Hua;
Lu, I-Cheng;
Lee, Su-Shin;
Kwan, Aij-Lie;
Chai, Chee-Yin;
Huang, Shu-Hung

Publication type:

Article

Present State and Future Perspectives of Prostaglandins as a Differentiation Factor in Motor Neurons.

Published in:

Cellular & Molecular Neurobiology, 2022, v. 42, n. 7, p. 2097, doi. 10.1007/s10571-021-01104-4

By:

Nango, Hiroshi;
Kosuge, Yasuhiro

Publication type:

Article

p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.1038276

By:

Buettner, Jannik M.;
Sowoidnich, Leonie;
Gerstner, Florian;
Blanco-Redondo, Beatriz;
Hallermann, Stefan;
Simon, Christian M.

Publication type:

Article

Visual three-dimensional spatial distribution of motor neurons innervating superficial limb muscles in mice.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 01, doi. 10.3389/fncel.2022.904172

By:

Zhidan Qi;
Shuai Han;
Shen Wang;
Xinyi Gu;
Jin Deng;
Chen Huang;
Xiaofeng Yin

Publication type:

Article

Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1527181

By:

Eckardt, Adam;
Marble, Charles;
Fern, Bradley;
Moritz, Henry;
Kotula, Charles;
Ke, Jiayi;
Rebancos, Clarisse;
Robertson, Samantha;
Nishimune, Hiroshi;
Suzuki, Masatoshi

Publication type:

Article

Role of Magnetic Resonance Imaging in Diagnosis of Motor Neuron Disease: Literature Review and Two Case Illustrations.

Published in:

Permanente Journal, 2019, v. 23, n. 1, p. 62, doi. 10.7812/TPP/18-131

By:

Sawalha, Khalid;
Gonzalez-Toledo, Eduardo;
Hussein, Omar

Publication type:

Article

A Platform to Understand Amyotrophic Lateral Sclerosis (ALS) and Extend Human Motor Neurons Longevity.

Published in:

International Journal of Morphology, 2019, v. 37, n. 4, p. 1203, doi. 10.4067/s0717-95022019000401203

By:

Cáceres, D. E.;
Torres, F. C.;
Castillo, C. A.;
Maureira, A.;
Franco-Campos, F. A.;
Osorio, M.;
Segovia, R.;
Tapia, J. C.;
Carrasco, M. A.

Publication type:

Article

The spectrum of lower motor neuron syndromes.

Published in:

Journal of Neurology, 2003, v. 250, n. 11, p. 1279, doi. 10.1007/s00415-003-0235-9

By:

van den Berg-Vos, R. M.;
van den Berg, L. H.;
Visser, J.;
de Visser, M.;
Franssen, H.;
Wokke, J. H. J.

Publication type:

Article

Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis.

Published in:

Journal of Neurology, 2000, v. 247, p. I17, doi. 10.1007/BF03161151

By:

Shaw, Pamela J.;
Eggett, C. J.

Publication type:

Article

Pathological involvement of the motor neuron system and hippocampal formation in motor neuron disease-inclusion dementia.

Published in:

Acta Neuropathologica, 2003, v. 106, n. 1, p. 50, doi. 10.1007/s00401-003-0696-z

By:

Toyoshima, Yasuko;
Piao, Yue-Shan;
Tan, Chun-Feng;
Morita, Masahiro;
Tanaka, Masaharu;
Oyanagi, Kiyomitsu;
Okamoto, Koichi;
Takahashi, Hitoshi

Publication type:

Article

Bunina body in frontal lobe dementia without clinical manifestations of motor neuron disease.

Published in:

Acta Neuropathologica, 2001, v. 101, n. 3, p. 281, doi. 10.1007/s004010000291

By:

Uchihara, Toshiki;
Sato, Toshiya;
Suzuki, Hiroko;
Ikeda, Kenji;
Akiyama, Haruhiko;
Takatori, Takehiko

Publication type:

Article

Three-Dimensional Mapping of Retrograde Multi-Labeled Motor Neuron Columns in the Spinal Cord.

Published in:

Photonics, 2021, v. 8, n. 5, p. 145, doi. 10.3390/photonics8050145

By:

Xu, Jianyi;
Yin, Xiaofeng;
Qi, Yisong;
Chen, Bo;
Li, Yusha;
Wan, Peng;
Yao, Yingtao;
Zhu, Dan;
Jiang, Baoguo;
Yu, Tingting

Publication type:

Article

The distribution and function of GDE2, a regulator of spinal motor neuron survival, are disrupted in Amyotrophic Lateral Sclerosis.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01376-x

By:

Westerhaus, Anna;
Joseph, Thea;
Meyers, Alison J.;
Jang, Yura;
Na, Chan Hyun;
Cave, Clinton;
Sockanathan, Shanthini

Publication type:

Article

The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01241-3

By:

Kovacs, Mariángeles;
Alamón, Catalina;
Maciel, Cecilia;
Varela, Valentina;
Ibarburu, Sofía;
Tarragó, Lucas;
King, Peter H.;
Si, Ying;
Kwon, Yuri;
Hermine, Olivier;
Barbeito, Luis;
Trias, Emiliano

Publication type:

Article

The Molecular Mechanisms Underlying Prostaglandin D2-Induced Neuritogenesis in Motor Neuron-Like NSC-34 Cells.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 934, doi. 10.3390/cells9040934

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Yoshimura, Nana;
Miyagishi, Hiroko;
Kanazawa, Takanori;
Hashizaki, Kaname;
Suzuki, Toyofumi;
Ishige, Kumiko

Publication type:

Article

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.

Published in:

Cells (2073-4409), 2019, v. 8, n. 6, p. 581, doi. 10.3390/cells8060581

By:

Bax, Monique;
McKenna, Jessie;
Do-Ha, Dzung;
Stevens, Claire H.;
Higginbottom, Sarah;
Balez, Rachelle;
Cabral-da-Silva, Mauricio e Castro;
Farrawell, Natalie E.;
Engel, Martin;
Poronnik, Philip;
Yerbury, Justin J.;
Saunders, Darren N.;
Ooi, Lezanne

Publication type:

Article

Physiological Biomarkers of Upper Motor Neuron Dysfunction in ALS.

Published in:

Brain Sciences (2076-3425), 2024, v. 14, n. 8, p. 760, doi. 10.3390/brainsci14080760

By:

Calma, Aicee Dawn;
van den Bos, Mehdi;
Pavey, Nathan;
Santos Silva, Cláudia;
Menon, Parvathi;
Vucic, Steve

Publication type:

Article

Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 5, p. 578, doi. 10.3390/brainsci11050578

By:

Gozutok, Oge;
Helmold, Benjamin Ryan;
Ozdinler, P. Hande;
Paolone, Giovanna;
Toyooka, Kazuhito

Publication type:

Article

Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the Sod1 Mouse Model of Amyotrophic Lateral Sclerosis.

Published in:

Brain Sciences (2076-3425), 2021, v. 11, n. 3, p. 369, doi. 10.3390/brainsci11030369

By:

Marques, Christine;
Burg, Thibaut;
Scekic-Zahirovic, Jelena;
Fischer, Mathieu;
Rouaux, Caroline;
Ozdinler, P. Hande;
Turner, Bradley

Publication type:

Article

Meta-analysis of differential gene expression in lower motor neurons isolated by laser capture microdissection from post-mortem ALS spinal cords.

Published in:

Frontiers in Genetics, 2024, p. 1, doi. 10.3389/fgene.2024.1385114

By:

Swindell, William R.

Publication type:

Article