Works matching Motor neurons

Results: 5000

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases.

Published in:

PLoS Genetics, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pgen.1006680

By:

Kline, Rachel A.;
Kaifer, Kevin A.;
Osman, Erkan Y.;
Carella, Francesco;
Tiberi, Ariana;
Ross, Jolill;
Pennetta, Giuseppa;
Lorson, Christian L.;
Murray, Lyndsay M.

Publication type:

Article

Motor Band Sign in Motor Neuron Disease: A Marker for Upper Motor Neuron Involvement.

Published in:

Canadian Journal of Neurological Sciences, 2023, v. 50, n. 3, p. 373, doi. 10.1017/cjn.2022.52

By:

Chung, Hee Sahng;
Melkus, Gerd;
Bourque, Pierre;
Chakraborty, Santanu

Publication type:

Article

Supraphysiological expression of survival motor neuron protein from an adenovirus vector does not adversely affect cell function.

Published in:

Biochemistry & Cell Biology, 2013, v. 91, n. 4, p. 252, doi. 10.1139/bcb-2012-0094

By:

Goulet, Benoit B.;
McFall, Emily R.;
Wong, Carmen M.;
Kothary, Rashmi;
Parks, Robin J.

Publication type:

Article

Spinal Cord Organoids to Study Motor Neuron Development and Disease.

Published in:

Life (2075-1729), 2023, v. 13, n. 6, p. 1254, doi. 10.3390/life13061254

By:

Buchner, Felix;
Dokuzluoglu, Zeynep;
Grass, Tobias;
Rodriguez-Muela, Natalia

Publication type:

Article

Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study.

Published in:

Brain Pathology, 2025, v. 35, n. 1, p. 1, doi. 10.1111/bpa.13286

By:

Murakami, Aya;
Koga, Shunsuke;
Fujioka, Shinsuke;
White, Adrianna E.;
Bieniek, Kevin F.;
Sekiya, Hiroaki;
DeJesus‐Hernandez, Mariely;
Finch, NiCole A.;
van Blitterswijk, Marka;
Nakamura, Masataka;
Tsuboi, Yoshio;
Murray, Melissa E.;
Wszolek, Zbigniew K.;
Dickson, Dennis W.

Publication type:

Article

Muscle regulates mTOR dependent axonal local translation in motor neurons via CTRP3 secretion: implications for a neuromuscular disorder, spinal muscular atrophy.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0806-3

By:

Rehorst, Wiebke A.;
Thelen, Maximilian P.;
Nolte, Hendrik;
Türk, Clara;
Cirak, Sebahattin;
Peterson, Jonathan M.;
Wong, G. William;
Wirth, Brunhilde;
Krüger, Marcus;
Winter, Dominic;
Kye, Min Jeong

Publication type:

Article

Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy.

Published in:

Journal of Anatomy, 2016, v. 228, n. 3, p. 443, doi. 10.1111/joa.12419

By:

Powis, Rachael A.;
Gillingwater, Thomas H.

Publication type:

Article

PuraMatrix hydrogel enhances the expression of motor neuron progenitor marker and improves adhesion and proliferation of motor neuron-like cells.

Published in:

Iranian Journal of Basic Medical Sciences, 2020, v. 23, n. 4, p. 431, doi. 10.22038/ijbms.2020.39797.9434

By:

Darvishi, Marzieh;
Hamidabadi, Hatef Ghasemi;
Negah, Sajad Sahab;
Moayeri, Ardeshir;
Tiraihi, Taki;
Mirnajafi-Zadeh, Javad;
Jahan-Abad, Ali Jahanbazi;
Shojaei, Amir

Publication type:

Article

Role of EphA4 in Mediating Motor Neuron Death in MND.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9430, doi. 10.3390/ijms22179430

By:

Zhao, Jing;
Stevens, Claire H.;
Boyd, Andrew W.;
Ooi, Lezanne;
Bartlett, Perry F.

Publication type:

Article

Motor neuron disease clinically limited to the lower motor neuron is a diffuse TDP-43 proteinopathy.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 4, p. 509, doi. 10.1007/s00401-011-0797-z

By:

Geser, Felix;
Stein, Beth;
Partain, Michael;
Elman, Lauren B.;
McCluskey, Leo F.;
Xie, Sharon X.;
Van Deerlin, Vivianna M.;
Kwong, Linda K.;
Lee, Virginia M.-Y.;
Trojanowski, John Q.

Publication type:

Article

Homozygous Survival Motor Neuron 2 Gene Deletion and Sporadic Lower Motor Neuron Disease in Children: Case Report and Literature Review.

Published in:

2013

By:

Liping, Lu;
Hongwei, Ma;
Lin, Wang

Publication type:

Case Study

Mills syndrome as a rare and significant motor neuron disease: a case report.

Published in:

2025

By:

Onder, Ozlem;
Isik, Sahin

Publication type:

Case Study

Superconditioning TMS for examining upper motor neuron function in MND.

Published in:

Experimental Brain Research, 2019, v. 237, n. 8, p. 2087, doi. 10.1007/s00221-019-05573-4

By:

Calancie, Blair;
Young, Eufrosina;
Watson, Mary Lou;
Wang, Dongliang;
Alexeeva, Natalia

Publication type:

Article

An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids.

Published in:

Cells (2073-4409), 2023, v. 12, n. 4, p. 545, doi. 10.3390/cells12040545

By:

Castellanos-Montiel, María José;
Chaineau, Mathilde;
Franco-Flores, Anna Kristyna;
Haghi, Ghazal;
Carrillo-Valenzuela, Dulce;
Reintsch, Wolfgang E.;
Chen, Carol X.-Q.;
Durcan, Thomas M.

Publication type:

Article

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1127, doi. 10.3390/cells10051127

By:

Cutarelli, Alessandro;
Martínez-Rojas, Vladimir A.;
Tata, Alice;
Battistella, Ingrid;
Rossi, Daniela;
Arosio, Daniele;
Musio, Carlo;
Conti, Luciano;
Pession, Andrea

Publication type:

Article

Highly Efficient Conversion of Motor Neuron-Like NSC-34 Cells into Functional Motor Neurons by Prostaglandin E2.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1741, doi. 10.3390/cells9071741

By:

Nango, Hiroshi;
Kosuge, Yasuhiro;
Sato, Masaki;
Shibukawa, Yoshiyuki;
Aono, Yuri;
Saigusa, Tadashi;
Ito, Yoshihisa;
Ishige, Kumiko

Publication type:

Article

The Timing and Extent of Motor Neuron Vulnerability in ALS Correlates with Accumulation of Misfolded SOD1 Protein in the Cortex and in the Spinal Cord.

Published in:

Cells (2073-4409), 2020, v. 9, n. 2, p. 502, doi. 10.3390/cells9020502

By:

Genc, Baris;
Gozutok, Oge;
Kocak, Nuran;
Ozdinler, P. Hande

Publication type:

Article

The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.

Published in:

Cells (2073-4409), 2019, v. 8, n. 6, p. 581, doi. 10.3390/cells8060581

By:

Bax, Monique;
McKenna, Jessie;
Do-Ha, Dzung;
Stevens, Claire H.;
Higginbottom, Sarah;
Balez, Rachelle;
Cabral-da-Silva, Mauricio e Castro;
Farrawell, Natalie E.;
Engel, Martin;
Poronnik, Philip;
Yerbury, Justin J.;
Saunders, Darren N.;
Ooi, Lezanne

Publication type:

Article

Targeting the full length of the motor end plate regions in the mouse forelimb increases the uptake of Fluoro-Gold into corresponding spinal cord motor neurons.

Published in:

Frontiers in Neurology, 2013, v. 4, p. 1, doi. 10.3389/fneur.2013.00058

By:

Tosolini, Andrew Paul;
Mohan, Rahul;
Morris, Renée

Publication type:

Article

Beta-band intermuscular coherence: a novel biomarker of upper motor neuron dysfunction in motor neuron disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2849, doi. 10.1093/brain/aws150

By:

Fisher, Karen M.;
Zaaimi, Boubker;
Williams, Timothy L.;
Baker, Stuart N.;
Baker, Mark R.

Publication type:

Article

Motor neuron disease group accompanied by inclusions of unidentified protein signaled by ubiquitin.

Published in:

Neuropathology, 2004, v. 24, n. 2, p. 117, doi. 10.1111/j.1440-1789.2003.00537.x

By:

Ikeda, Kenji;
Tsuchiya, Kuniaki

Publication type:

Article

Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.578143

By:

Lin, Jianing;
Huang, Pian;
Chen, Weineng;
Ye, Chenghui;
Su, Huanxing;
Yao, Xiaoli

Publication type:

Article

Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases: An Overview.

Published in:

Neurodiagnostic Journal, 2015, v. 55, n. 3, p. 180, doi. 10.1080/21646821.2015.1075181

By:

Morris, Jerry

Publication type:

Article

Derivation of motor neuron-like cells from neonatal mouse testis in a simple culture condition.

Published in:

Andrologia, 2016, v. 48, n. 10, p. 1100, doi. 10.1111/and.12545

By:

Javanmardy, S.;
Asadi, M. H.;
Movahedin, M.;
Moradpour, F.;
Bahadoran, H.

Publication type:

Article

Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells.

Published in:

Molecular Brain, 2015, v. 8, p. 1, doi. 10.1186/s13041-015-0172-4

By:

Shimojo, Daisuke;
Onodera, Kazunari;
Doi-Torii, Yukiko;
Ishihara, Yasuharu;
Hattori, Chinatsu;
Miwa, Yukino;
Tanaka, Satoshi;
Okada, Rina;
Ohyama, Manabu;
Shoji, Masanobu;
Nakanishi, Atsushi;
Doyu, Manabu;
Okano, Hideyuki;
Okada, Yohei

Publication type:

Article

Present State and Future Perspectives of Prostaglandins as a Differentiation Factor in Motor Neurons.

Published in:

Cellular & Molecular Neurobiology, 2022, v. 42, n. 7, p. 2097, doi. 10.1007/s10571-021-01104-4

By:

Nango, Hiroshi;
Kosuge, Yasuhiro

Publication type:

Article

Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.

Published in:

Frontiers in Neuroscience, 2025, p. 1, doi. 10.3389/fnins.2025.1527181

By:

Eckardt, Adam;
Marble, Charles;
Fern, Bradley;
Moritz, Henry;
Kotula, Charles;
Ke, Jiayi;
Rebancos, Clarisse;
Robertson, Samantha;
Nishimune, Hiroshi;
Suzuki, Masatoshi

Publication type:

Article

The spectrum of lower motor neuron syndromes.

Published in:

Journal of Neurology, 2003, v. 250, n. 11, p. 1279, doi. 10.1007/s00415-003-0235-9

By:

van den Berg-Vos, R. M.;
van den Berg, L. H.;
Visser, J.;
de Visser, M.;
Franssen, H.;
Wokke, J. H. J.

Publication type:

Article

Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis.

Published in:

Journal of Neurology, 2000, v. 247, p. I17, doi. 10.1007/BF03161151

By:

Shaw, Pamela J.;
Eggett, C. J.

Publication type:

Article

Activation of IGF-1/GLP-1 Signalling via 4-Hydroxyisoleucine Prevents Motor Neuron Impairments in Experimental ALS-Rats Exposed to Methylmercury-Induced Neurotoxicity.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3878, doi. 10.3390/molecules27123878

By:

Shandilya, Ambika;
Mehan, Sidharth;
Kumar, Sumit;
Sethi, Pranshul;
Narula, Acharan S.;
Alshammari, Abdulrahman;
Alharbi, Metab;
Alasmari, Abdullah F.

Publication type:

Article

Three-Dimensional Mapping of Retrograde Multi-Labeled Motor Neuron Columns in the Spinal Cord.

Published in:

Photonics, 2021, v. 8, n. 5, p. 145, doi. 10.3390/photonics8050145

By:

Xu, Jianyi;
Yin, Xiaofeng;
Qi, Yisong;
Chen, Bo;
Li, Yusha;
Wan, Peng;
Yao, Yingtao;
Zhu, Dan;
Jiang, Baoguo;
Yu, Tingting

Publication type:

Article

ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01852-6

By:

Zelina, Pavol;
de Ruiter, Anna Aster;
Kolsteeg, Christy;
van Ginneken, Ilona;
Vos, Harmjan R.;
Supiot, Laura F.;
Burgering, Boudewijn M. T.;
Meye, Frank J.;
Veldink, Jan H.;
van den Berg, Leonard H.;
Pasterkamp, R. Jeroen

Publication type:

Article

ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons.

Published in:

Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01852-6

By:

Zelina, Pavol;
de Ruiter, Anna Aster;
Kolsteeg, Christy;
van Ginneken, Ilona;
Vos, Harmjan R.;
Supiot, Laura F.;
Burgering, Boudewijn M. T.;
Meye, Frank J.;
Veldink, Jan H.;
van den Berg, Leonard H.;
Pasterkamp, R. Jeroen

Publication type:

Article

The distribution and function of GDE2, a regulator of spinal motor neuron survival, are disrupted in Amyotrophic Lateral Sclerosis.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01376-x

By:

Westerhaus, Anna;
Joseph, Thea;
Meyers, Alison J.;
Jang, Yura;
Na, Chan Hyun;
Cave, Clinton;
Sockanathan, Shanthini

Publication type:

Article

Survival motor neuron protein protects H9c2 cardiomyocytes from hypoxia‐induced cell injury by reducing apoptosis.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2020, v. 47, n. 11, p. 1808, doi. 10.1111/1440-1681.13369

By:

Zhong, Xiao;
Song, Ziguang;
Song, Xiang

Publication type:

Article

A Crucial Role for the Protein Quality Control System in Motor Neuron Diseases.

Published in:

Frontiers in Aging Neuroscience, 2020, v. 12, p. 1, doi. 10.3389/fnagi.2020.00191

By:

Cristofani, Riccardo;
Crippa, Valeria;
Cicardi, Maria Elena;
Tedesco, Barbara;
Ferrari, Veronica;
Chierichetti, Marta;
Casarotto, Elena;
Piccolella, Margherita;
Messi, Elio;
Galbiati, Mariarita;
Rusmini, Paola;
Poletti, Angelo

Publication type:

Article

Measurement of spinal cord atrophy using phase sensitive inversion recovery (PSIR) imaging in motor neuron disease.

Published in:

PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0208255

By:

Olney, Nicholas T.;
Bischof, Antje;
Rosen, Howard;
Caverzasi, Eduardo;
Stern, William A.;
Lomen-Hoerth, Catherine;
Miller, Bruce L.;
Henry, Roland G.;
Papinutto, Nico

Publication type:

Article

Erythropoietin attenuates motor neuron programmed cell death in a burn animal model.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190039

By:

Wu, Sheng-Hua;
Lu, I-Cheng;
Lee, Su-Shin;
Kwan, Aij-Lie;
Chai, Chee-Yin;
Huang, Shu-Hung

Publication type:

Article

Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0188912

By:

Kondori, Nazanin Rahmani;
Paul, Praveen;
Robbins, Jacqueline P.;
Liu, Ke;
Hildyard, John C. W.;
Wells, Dominic J.;
de Belleroche, Jacqueline S.

Publication type:

Article

Motor neurons and the generation of spinal motor neuron diversity.

Published in:

Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00293

By:

Stifani, Nicolas

Publication type:

Article

Key Disease Mechanisms Linked to Amyotrophic Lateral Sclerosis in Spinal Cord Motor Neurons.

Published in:

Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.825031

By:

Bottero, Virginie;
Santiago, Jose A.;
Quinn, James P.;
Potashkin, Judith A.

Publication type:

Article

Amyotrophic Lateral Sclerosis: A Neurodegenerative Motor Neuron Disease With Ocular Involvement.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.566858

By:

Rojas, Pilar;
Ramírez, Ana I.;
Fernández-Albarral, José A.;
López-Cuenca, Inés;
Salobrar-García, Elena;
Cadena, Manuel;
Elvira-Hurtado, Lorena;
Salazar, Juan J.;
de Hoz, Rosa;
Ramírez, José M.

Publication type:

Article

Circulating MicroRNAs as Diagnostic Biomarkers for Motor Neuron Disease.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00354

By:

Wang, Lin;
Zhang, Lijuan

Publication type:

Article

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 13, p. 3811, doi. 10.1523/JNEUROSCI.2396-15.2016

By:

Fallini, Claudia;
Donlin-Asp, Paul G.;
Rouanet, Jeremy P.;
Bassell, Gary J.;
Rossoll, Wilfried

Publication type:

Article

Can the electrically stimulated manual muscle test differentiate upper from lower motor neuron injury in persons with acute SCI?

Published in:

Neurological Research, 2023, v. 45, n. 10, p. 906, doi. 10.1080/01616412.2020.1824417

By:

de Padua, Ashley;
Renfro, Cassandra;
Grabnar, Maria;
Kilgore, Kevin;
Bryden, Anne;
Roach, Mary Joan;
Nemunaitis, Greg

Publication type:

Article

DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-019-0874-4

By:

Kim, Byung Woo;
Jeong, Ye Eun;
Wong, Margaret;
Martin, Lee J.

Publication type:

Article

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles.

Published in:

FEBS Open Bio, 2021, v. 11, n. 2, p. 494, doi. 10.1002/2211-5463.13059

By:

Otake, Kentaro;
Adachi‐Tominari, Keiko;
Nagai, Hiroaki;
Saito, Masayo;
Sano, Osamu;
Hirozane, Yoshihiko;
Iwata, Hidehisa

Publication type:

Article

Nonalcoholic Fatty Liver Disease in Patients with Inherited and Sporadic Motor Neuron Degeneration.

Published in:

Genes, 2022, v. 13, n. 6, p. 936, doi. 10.3390/genes13060936

By:

Johnson, Brian;
Kokkinis, Angela;
Gai, Neville;
Shamim, Ejaz A.;
Blackstone, Craig;
Fischbeck, Kenneth H.;
Grunseich, Christopher

Publication type:

Article

A Novel Variant in Superoxide Dismutase 1 Gene (p.V119M) in Als Patients with Pure Lower Motor Neuron Presentation.

Published in:

Genes, 2021, v. 12, n. 10, p. 1544, doi. 10.3390/genes12101544

By:

Ricci, Claudia;
Giannini, Fabio;
Riolo, Giulia;
Bocci, Silvia;
Casali, Stefania;
Battistini, Stefania

Publication type:

Article

Subacute combined degeneration of the spinal cord masking motor neuron disease: a case report.

Published in:

2019

By:

Loveland, Paula;
Wong, Aaron;
Vivekanandam, Vinojini;
Lim, Wen Kwang

Publication type:

journal article