Works matching Melphalan

Results: 3089

Hybrid Molecules of Benzylguanidine and the Alkylating Group of Melphalan: Synthesis and Effects on Neuroblastoma Cells.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 13, p. 4469, doi. 10.3390/jcm12134469

By:

Bruchelt, Gernot;
Klose, Chihab;
Lischka, Matthias;
Brandes, Marietta;
Handgretinger, Rupert;
Brueckner, Reinhard

Publication type:

Article

Stability of Captisol-enabled versus propylene glycol–based melphalan at room temperature and after refrigeration.

Published in:

American Journal of Health-System Pharmacy, 2022, v. 79, n. 12, p. 1011, doi. 10.1093/ajhp/zxac055

By:

Kawedia, Jitesh D;
Ramchandran, Sumankalai;
Liu, Xiaoqian;
Gulbis, Alison M;
Titus, Mark;
Bashir, Qaiser;
Qazilbash, Muzaffar H;
Champlin, Richard E;
Ciurea, Stefan O

Publication type:

Article

Busulfan, melphalan, and bortezomib compared to melphalan as a high dose regimen for autologous hematopoietic stem cell transplantation in multiple myeloma: long term follow up of a novel high dose regimen.

Published in:

Leukemia & Lymphoma, 2020, v. 61, n. 14, p. 3484, doi. 10.1080/10428194.2020.1811275

By:

Hagen, Patrick;
D'Souza, Anita;
Hari, Parameswaran;
Davila, Omar;
Zhang, Mei-Jie;
Vesole, David H.;
Smith, Scott E.;
Rodriguez, Tulio E.;
Stiff, Patrick J.

Publication type:

Article

High melphalan exposure is associated with improved overall survival in myeloma patients receiving high dose melphalan and autologous transplantation.

Published in:

British Journal of Clinical Pharmacology, 2016, v. 82, n. 1, p. 149, doi. 10.1111/bcp.12906

By:

Nath, Christa E.;
Trotman, Judith;
Tiley, Campbell;
Presgrave, Peter;
Joshua, Douglas;
Kerridge, Ian;
Kwan, Yiu Lam;
Gurney, Howard;
McLachlan, Andrew J.;
Earl, John W.;
Nivison‐Smith, Ian;
Zeng, Lihua;
Shaw, Peter J.

Publication type:

Article

Busulfan plus melphalan versus high-dose melphalan as a conditioning regimen for autologous stem cell transplantation in multiple myeloma with high-risk features (KMM 2015).

Published in:

Annals of Hematology, 2023, v. 102, n. 8, p. 2233, doi. 10.1007/s00277-023-05308-0

By:

Kim, Mihee;
Lee, Je-Jung;
Min, Chang-Ki;
Lee, Ji Yun;
Jo, Jae-Cheol;
Yoon, Sung-Soo;
Lim, Sung-Nam;
Do, Young Rok;
Kim, Kihyun;
Lee, Jae Hoon;
Yoo, Kwai Han;
Bae, Sung Hwa;
Yi, Jun Ho;
Jung, Jongheon;
Eom, Hyeon-Seok;
Jung, Sung-Hoon

Publication type:

Article

Predictors of increased melphalan exposure correlate with overall survival, nonrelapse mortality, and toxicities in patients undergoing reduced-intensity allogeneic stem cell transplantation with fludarabine and melphalan.

Published in:

Journal of Oncology Pharmacy Practice, 2021, v. 27, n. 3, p. 579, doi. 10.1177/1078155220927436

By:

Sweiss, Karen;
Calip, Gregory Sampang;
Holden, Jaime;
Lewkowski, Paulina;
Mialik, Iryna;
Johnson, Jeremy;
Galvin, John P;
Rondelli, Damiano;
Patel, Pritesh

Publication type:

Article

Evaluating the adverse effects of melphalan formulations.

Published in:

Journal of Oncology Pharmacy Practice, 2019, v. 25, n. 7, p. 1631, doi. 10.1177/1078155218804042

By:

Xiang, Elaine;
Ni, Jian;
Glotzbecker, Brett;
Laubach, Jacob;
Soiffer, Robert;
McDonnell, Anne M

Publication type:

Article

Solution stability of Captisol-stabilized melphalan (Evomela) versus Propylene glycol-based melphalan hydrochloride injection.

Published in:

Pharmaceutical Development & Technology, 2018, v. 23, n. 10, p. 1024, doi. 10.1080/10837450.2016.1265557

By:

Singh, Ramsharan;
Chen, Jin;
Miller, Teresa;
Bergren, Michael;
Mallik, Rangan

Publication type:

Article

Long-term outcomes of busulfan plus melphalan-based versus melphalan 200 mg/m<sup>2</sup> conditioning regimens for autologous hematopoietic stem cell transplantation in patients with multiple myeloma: a systematic review and meta-analysis.

Published in:

2021

By:

Gao, Fei;
Lin, Mei-Si;
You, Jie-Shu;
Zhang, Min-Yue;
Cheng, Long;
Lin, Ke;
Zhao, Peng;
Chen, Qi-Yan

Publication type:

Literature Review

Melphalan induced germ cell toxicity and dose‐dependent effects of β‐aminoisobutyric acid in experimental rat model: Role of oxidative stress, inflammation and apoptosis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 8, p. 1, doi. 10.1002/jbt.23374

By:

Panghal, Archna;
Kumar, Vinod;
Jena, Gopabandhu

Publication type:

Article

Busulfan/Cyclophosphamide Compared with Melphalan as a Conditioning Regimen for Autologous Transplantation of Multiple Myeloma: A Long-Term Assessment.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 19, p. 6239, doi. 10.3390/jcm12196239

By:

Zhou, Shiyuan;
Zhai, Yingying;
Yan, Lingzhi;
Shi, Xiaolan;
Shang, Jingjing;
Wu, Depei;
Fu, Chengcheng;
Jin, Song

Publication type:

Article

Treatment of Multiple Myeloma and the Role of Melphalan in the Era of Modern Therapies—Current Research and Clinical Approaches.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 9, p. 1841, doi. 10.3390/jcm10091841

By:

Poczta, Anastazja;
Rogalska, Aneta;
Marczak, Agnieszka;
Kumar, Shaji

Publication type:

Article

Efficacy of intravitreal injections of melphalan in the treatment of retinoblastoma vitreous seeding.

Published in:

Advances in Clinical & Experimental Medicine, 2024, v. 33, n. 2, p. 119, doi. 10.17219/acem/166180

By:

Cieślik, Krzysztof;
Rogowska, Anna;
Danowska, Małgorzata;
Hautz, Wojciech

Publication type:

Article

Addition of thalidomide to melphalan and prednisone treatment prolongs survival in multiple myeloma - a retrospective population based study of 1162 patients.

Published in:

European Journal of Haematology, 2014, v. 92, n. 1, p. 19, doi. 10.1111/ejh.12213

By:

Lund, Johan;
Uttervall, Katarina;
Liwing, Johan;
Gahrton, Gösta;
Alici, Evren;
Aschan, Johan;
Holmberg, Erik;
Nahi, Hareth

Publication type:

Article

Impact of concurrent gabapentin or pregabalin with high‐dose melphalan in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplant.

Published in:

Pharmacotherapy, 2022, v. 42, n. 3, p. 233, doi. 10.1002/phar.2667

By:

Sivakumar, Akhilesh;
Bryson, Evan B.;
Hall, Kevin H.;
Maples, Kathryn T.;
Goyal, Subir;
Joseph, Nisha S.;
Hofmeister, Craig C.;
Kaufman, Jonathan L.;
Lonial, Sagar;
Nooka, Ajay K.;
Harvey, Robert Donald

Publication type:

Article

Toxicity assessment of concurrent gabapentin/pregabalin administration with high-dose melphalan in autologous hematopoietic cell transplant recipients.

Published in:

2021

By:

Angus, Jonathan;
Cumpston, Aaron;
Veltri, Lauren;
Ross, Kelly G.;
Wen, Sijin;
Dillaman, Megan

Publication type:

journal article

Symptom experience of multiple myeloma (syMMex) patients treated with autologous stem cell transplantation following high-dose melphalan: a descriptive longitudinal study.

Published in:

2018

By:

Naegele, Matthias;
Kirsch, Monika;
Ihorst, Gabriele;
Fierz, Katharina;
Engelhardt, Monika;
De Geest, Sabina

Publication type:

journal article

Aprepitant for the control of delayed nausea and vomiting associated with the use of high-dose melphalan for autologous peripheral blood stem cell transplants in patients with multiple myeloma: a phase II study.

Published in:

Supportive Care in Cancer, 2014, v. 22, n. 11, p. 2911, doi. 10.1007/s00520-014-2248-6

By:

Bechtel, Thomas;
McBride, Ali;
Crawford, Brooke;
Bullington, Susan;
Hofmeister, Craig;
Benson, Don;
Jaglowski, Samantha;
Penza, Sam;
Andritsos, Leslie;
Devine, Steven

Publication type:

Article

A systematic review of inter-individual differences in the DNA repair processes involved in melphalan monoadduct repair in relation to treatment outcomes.

Published in:

Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 5, p. 755, doi. 10.1007/s00280-021-04340-z

By:

van Kan, Maia;
Burns, Kathryn E.;
Helsby, Nuala A.

Publication type:

Article

Inhibition of HSP90 overcomes melphalan resistance through downregulation of Src in multiple myeloma cells.

Published in:

Clinical & Experimental Medicine, 2020, v. 20, n. 1, p. 63, doi. 10.1007/s10238-019-00587-2

By:

Tabata, Mitsuki;
Tsubaki, Masanobu;
Takeda, Tomoya;
Tateishi, Keisuke;
Maekawa, Saho;
Tsurushima, Katsumasa;
Imano, Motohiro;
Satou, Takao;
Ishizaka, Toshihiko;
Nishida, Shozo

Publication type:

Article

Differential binding of plasma proteins by liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the bilayer.

Published in:

Biochemistry (00062979), 2014, v. 79, n. 8, p. 797, doi. 10.1134/S0006297914080070

By:

Kuznetsova, N.;
Vodovozova, E.

Publication type:

Article

Paperspray Ionization Mass Spectrometry as a Tool for Predicting Real-Time Optimized Dosing of the Chemotherapeutic Drug Melphalan.

Published in:: Journal of Applied Laboratory Medicine, 2021, v. 6, n. 3, p. 625, doi. 10.1093/jalm/jfaa237
Publication type:: Article

Melphalan as a Promising Treatment for BRCA-Related Ovarian Carcinoma.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.716467

By:

Conteduca, Vincenza;
Scarpi, Emanuela;
Farolfi, Alberto;
Brighi, Nicole;
Rossi, Lorena;
Gurioli, Giorgia;
Lolli, Cristian;
Schepisi, Giuseppe;
Bleve, Sara;
Gianni, Caterina;
Virga, Alessandra;
Altavilla, Amelia;
Burgio, Salvatore Luca;
Menna, Cecilia;
De Giorgi, Ugo

Publication type:

Article

Altered T-Lymphocyte Biology Following High-Dose Melphalan and Autologous Stem Cell Transplantation With Implications for Adoptive T-Cell Therapy.

Published in:

Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.568056

By:

Mika, Thomas;
Ladigan-Badura, Swetlana;
Maghnouj, Abdelouahid;
Mustafa, Bakr;
Klein-Scory, Susanne;
Baraniskin, Alexander;
Döhring, Sascha;
Fuchs, Ilka;
Ehl, Stephan;
Hahn, Stephan A.;
Schroers, Roland

Publication type:

Article

Incidence of leukopenia and thrombocytopenia with cisplatin plus mitomycin-c versus melphalan in patients undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).

Published in:

2018

By:

Hakeam, Hakeam A.;
Arab, Amal;
Azzam, Ayman;
Alyahya, Zyad;
Eldali, Abdelmoneim M.;
Amin, Tarek

Publication type:

journal article

Intravitreal injection of melphalan for intraocular retinoblastoma.

Published in:

Japanese Journal of Ophthalmology, 2015, v. 59, n. 3, p. 164, doi. 10.1007/s10384-015-0378-0

By:

Suzuki, Shigenobu;
Aihara, Yukiko;
Fujiwara, Miyuki;
Sano, Shuichi;
Kaneko, Akihiro

Publication type:

Article

Selective ophthalmic arterial injection of melphalan for intraocular retinoblastoma: a 4-year review.

Published in:

Japanese Journal of Ophthalmology, 2015, v. 59, n. 2, p. 109, doi. 10.1007/s10384-014-0356-y

By:

Ong, Sherine;
Chao, An-Ning;
Wong, Ho-Fai;
Liou, Kuan-Lyin;
Kao, Ling-Yuh

Publication type:

Article

Autologous stem cell transplant for multiple myeloma: Impact of melphalan dose on the transplant outcome.

Published in:

Leukemia & Lymphoma, 2023, v. 64, n. 2, p. 378, doi. 10.1080/10428194.2022.2148214

By:

Kumar, Lalit;
Sahoo, Ranjit Kumar;
Kumar, Sudhir;
Baa, Annie K.;
Tansir, Ghazal;
Pathak, Neha;
Malik, Prabhat S.;
Sharma, Om Dutt;
Mathew, Anisha;
Jha, Ankit;
Gupta, Ritu;
Sharma, Atul;
Biswas, Ahitagni;
Kumar, Rakesh;
Thulkar, Sanjay;
Malik, Soumyaranjan;
Dutt, Ashish

Publication type:

Article

Increased early mortality after fludarabine and melphalan conditioning with peripheral blood grafts in haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide.

Published in:

2022

By:

Eastburg, Luke;
Russler-Germain, David A.;
DiPersio, John F.;
Fountaine, Thomas;
Andolina, Jeffrey R.;
Abboud, Ramzi;
Huselton, Eric

Publication type:

Letter

Bortezomib-based induction therapy followed by intravenous busulfan-melphalan as conditioning regimen for patients with newly diagnosed multiple myeloma.

Published in:

Leukemia & Lymphoma, 2015, v. 56, n. 2, p. 415, doi. 10.3109/10428194.2014.922182

By:

Blanes, Margarita;
González, José D.;
Lahuerta, Juan J.;
Ribas, Paz;
Lorenzo, Ignacio;
Boluda, Blanca;
Sanz, Miguel A.;
de la Rubia, Javier

Publication type:

Article

Bendamustine and melphalan kill myeloma cells similarly through reactive oxygen species production and activation of the p53 pathway and do not overcome resistance to each other.

Published in:

Leukemia & Lymphoma, 2014, v. 55, n. 9, p. 2165, doi. 10.3109/10428194.2013.871277

By:

Surget, Sylvanie;
Lemieux-Blanchard, Emilie;
Maïga, Sophie;
Descamps, Géraldine;
Le Gouill, Steven;
Moreau, Philippe;
Amiot, Martine;
Pellat-Deceunynck, Catherine

Publication type:

Article

Anesthetic management of super‑selective intra‑arterial Melphalan injection in an infant with retinoblastoma.

Published in:

Saudi Journal of Anaesthesia, 2023, v. 17, n. 3, p. 434, doi. 10.4103/sja.sja_236_23

By:

Vaithialingam, Balaji;
Gopal, Swaroop;
Chandrashekhar, Shishir;
Mallik, Dattatraya

Publication type:

Article

One Case of Abnormal Decrease of Interferon Gamma Release Assay Result Caused by Melphalan.

Published in:

Clinical Laboratory, 2024, v. 70, n. 9, p. 1795, doi. 10.7754/Clin.Lab.2024.240437

By:

Gangfeng Li;
Tao Lu;
Ningping Shan

Publication type:

Article

The Combination of Panobinostat and Melphalan for the Treatment of Patients with Multiple Myeloma.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15671, doi. 10.3390/ijms232415671

By:

Gkotzamanidou, Maria;
Terpos, Evangelos;
Dimopoulos, Meletios A.;
Souliotis, Vassilis L.

Publication type:

Article

Newly Synthesized Melphalan Analogs Induce DNA Damage and Mitotic Catastrophe in Hematological Malignant Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14258, doi. 10.3390/ijms232214258

By:

Poczta, Anastazja;
Krzeczyński, Piotr;
Ionov, Maksim;
Rogalska, Aneta;
Gaipl, Udo S.;
Marczak, Agnieszka;
Lubgan, Dorota

Publication type:

Article

Synthesis and In Vitro Activity of Novel Melphalan Analogs in Hematological Malignancy Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1760, doi. 10.3390/ijms23031760

By:

Poczta, Anastazja;
Krzeczyński, Piotr;
Tobiasz, Joanna;
Rogalska, Aneta;
Gajek, Arkadiusz;
Marczak, Agnieszka

Publication type:

Article

Diffuse chorioretinal atrophy after a single standard low- dose intravitreal melphalan injection in a child with retinoblastoma: a case report.

Published in:

2016

By:

An-Ning Chao;
Ling-Yuh Kao;
Liu, Laura;
Nan-Kai Wang;
Chao, An- Ning;
Kao, Ling-Yuh;
Wang, Nan-Kai

Publication type:

journal article

ERG and OCT abnormalities in retinoblastoma after melphalan intravitreous injection.

Published in:

2024

By:

de Albuquerque, Marina L.;
Moreto, Renata;
Bergamo, Maristella;
Corrêa, Zélia M.;
Jorge, Rodrigo

Publication type:

Case Study

Clinical Impact of Melphalan Pharmacokinetics on Transplantation Outcomes in Children Undergoing Hematopoietic Stem Cell Transplantation.

Published in:

Cell Transplantation, 2022, v. 31, p. 1, doi. 10.1177/09636897221143364

By:

Maemura, Ryo;
Wakamatsu, Manabu;
Matsumoto, Kana;
Sakaguchi, Hirotoshi;
Yoshida, Nao;
Hama, Asahito;
Yoshida, Taro;
Miwata, Shunsuke;
Kitazawa, Hironobu;
Narita, Kotaro;
Kataoka, Shinsuke;
Ichikawa, Daisuke;
Hamada, Motoharu;
Taniguchi, Rieko;
Suzuki, Kyogo;
Kawashima, Nozomu;
Nishikawa, Eri;
Narita, Atsushi;
Okuno, Yusuke;
Nishio, Nobuhiro

Publication type:

Article

Evaluation of gastrointestinal complications in Egyptian patients after autologous stem cell transplantation using melphalan-based regimens.

Published in:

Egyptian Journal of Internal Medicine, 2023, v. 35, n. 1, p. 1, doi. 10.1186/s43162-023-00213-4

By:

Abdelaty, Mona Mahrous;
Al-Hosiny, Fatma;
Mashaal, Raghda Gabr

Publication type:

Article

Test‐dose pharmacokinetics guided melphalan dose adjustment in reduced intensity conditioning allogeneic transplant for non‐malignant disorders.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 115, doi. 10.1111/bcp.14932

By:

Chandra, Sharat;
Mizuno, Kana;
Zhao, Junfang;
Davies, Stella M.;
Marsh, Rebecca A.;
Fukuda, Tsuyoshi;
Setchell, Kenneth D. R.;
Vinks, Alexander A.;
Mehta, Parinda A.

Publication type:

Article

Isolated limb perfusion with melphalan activates interferon-stimulated genes to induce tumor regression in patients with melanoma in-transit metastasis.

Published in:

OncoImmunology, 2020, v. 9, n. 1, p. 1, doi. 10.1080/2162402X.2019.1684126

By:

Johansson, Junko;
Kiffin, Roberta;
Aydin, Ebru;
Nilsson, Malin S.;
Hellstrand, Kristoffer;
Lindnér, Per;
Naredi, Peter;
Olofsson Bagge, Roger;
Martner, Anna

Publication type:

Article

A case of melphalan sustained accumulation in an 80-year old patient.

Published in:

2015

By:

Jolivot, Pierre-Alain;
Poinsignon, Vianney;
Paci, Angelo;
Guidet, Bertrand;
Pichereau, Claire;
Fernandez, Christine;
Hindlet, Patrick

Publication type:

journal article

Melphalan on day -1 versus day -2 in patients with plasma cell disorders undergoing autologous stem cell transplant.

Published in:

Journal of Oncology Pharmacy Practice, 2023, v. 29, n. 6, p. 1398, doi. 10.1177/10781552221125871

By:

Watson, Aleksandra N;
Shah, Shreya A;
Shalhoub, Sila D;
Piedra, Katrina M;
Komanduri, Krishna V;
Kwon, Deukwoo;
Pereira, Denise L

Publication type:

Article

Cyclical 10‐day dosing of melphalan for canine multiple myeloma.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 3, p. 533, doi. 10.1111/vco.12916

By:

Teddy, Lucy;
Sylvester, Skylar R.;
O'Connor, Kelly S.;
Hume, Kelly R.

Publication type:

Article

Oral melphalan for the treatment of relapsed canine lymphoma.

Published in:

Veterinary & Comparative Oncology, 2018, v. 16, n. 1, p. E123, doi. 10.1111/vco.12356

By:

Mastromauro, M. L.;
Suter, S. E.;
Hauck, M. L.;
Hess, P. R.

Publication type:

Article

Challenges associated with test dose pharmacokinetic predictions of high dose melphalan exposure in patients with multiple myeloma.

Published in:

European Journal of Clinical Pharmacology, 2022, v. 78, n. 12, p. 1911, doi. 10.1007/s00228-022-03396-x

By:

Nath, Christa Ellen;
Grigg, Andrew;
Rosser, Sebastian P. A.;
Estell, Jane;
Newman, Elizabeth;
Tiley, Campbell;
Ramanathan, Sundra;
Ho, Shir Jing;
Larsen, Stephen;
Gibson, John;
Presgrave, Peter;
Shaw, Peter John;
Trotman, Judith

Publication type:

Article

Clinical and pathomorphological changes in the rabbit retina after an injection of various doses of the cytostatic melphalan.

Published in:

Journal of Ophthalmology (Ukraine) / Oftalʹmologičeskij Žurnal, 2023, n. 5, p. 41, doi. 10.31288/oftalmolzh202354145

By:

Bobrova, N. F.;
Sorochynska, T. A.;
Tronina, S. A.;
Romanova, T. V.;
Molachaniuk, N. I.;
Bratishko, O. Iu.;
Shylyk, A. V.

Publication type:

Article

Ultrastructural changes in the rabbit retina after various one-time doses of intravitreal melphalan.

Published in:

Journal of Ophthalmology (Ukraine) / Oftalʹmologičeskij Žurnal, 2020, n. 4, p. 50, doi. 10.31288/oftalmolzh202045055

By:

Bobrova, N. F.;
Sorochynska, T. A.;
Molachaniuk, N. I.;
Bratishko, A. Iu.

Publication type:

Article

Safety and Efficacy of Intravitreal Chemotherapy (Melphalan) to Treat Vitreous Seeds in Retinoblastoma.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.696787

By:

Yousef, Yacoub A.;
Al Jboor, Mays;
Mohammad, Mona;
Mehyar, Mustafa;
Toro, Mario D.;
Nazzal, Rashed;
Alzureikat, Qusai H.;
Rejdak, Magdalena;
Elfalah, Mutasem;
Sultan, Iyad;
Rejdak, Robert;
Al-Hussaini, Maysa;
Al-Nawaiseh, Ibrahim

Publication type:

Article