Works matching Maturation inhibitors

Results: 319
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    Antiviral Activity, Safety, and Exposure–Response Relationships of GSK3532795, a Second-Generation Human Immunodeficiency Virus Type 1 Maturation Inhibitor, Administered as Monotherapy or in Combination With Atazanavir With or Without Ritonavir in a Phase 2a Randomized, Dose-Ranging, Controlled Trial (AI468002).

    Published in:
    Clinical Infectious Diseases, 2017, v. 65, n. 3, p. 442, doi. 10.1093/cid/cix239
    By:
    • Hwang, Carey;
    • Schürmann, Dirk;
    • Sobotha, Christian;
    • Boffito, Marta;
    • Sevinsky, Heather;
    • Ray, Neelanjana;
    • Ravindran, Palanikumar;
    • Hong Xiao;
    • Keicher, Christian;
    • Hüser, Andreas;
    • Krystal, Mark;
    • Dicker, Ira B.;
    • Grasela, Dennis;
    • Lataillade, Max
    Publication type:
    Article
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    A Phase IIa Study Evaluating Safety, Pharmacokinetics, and Antiviral Activity of GSK2838232, a Novel, Second-generation Maturation Inhibitor, in Participants With Human Immunodeficiency Virus Type 1 Infection.

    Published in:
    Clinical Infectious Diseases, 2020, v. 71, n. 5, p. 1255, doi. 10.1093/cid/ciz938
    By:
    • DeJesus, Edwin;
    • Harward, Sara;
    • Jewell, Roxanne C;
    • Johnson, Mark;
    • Dumont, Etienne;
    • Wilches, Viviana;
    • Halliday, Fiona;
    • Talarico, Christine L;
    • Jeffrey, Jerry;
    • Gan, Jianjun;
    • Xu, Jianfeng;
    • Felizarta, Franco;
    • Scribner, Anita;
    • Ramgopal, Moti;
    • Benson, Paul;
    • Johns, Brian A
    Publication type:
    Article
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    Structural basis of HIV-1 maturation inhibitor binding and activity.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36569-y
    By:
    • Sarkar, Sucharita;
    • Zadrozny, Kaneil K.;
    • Zadorozhnyi, Roman;
    • Russell, Ryan W.;
    • Quinn, Caitlin M.;
    • Kleinpeter, Alex;
    • Ablan, Sherimay;
    • Meshkin, Hamed;
    • Perilla, Juan R.;
    • Freed, Eric O.;
    • Ganser-Pornillos, Barbie K.;
    • Pornillos, Owen;
    • Gronenborn, Angela M.;
    • Polenova, Tatyana
    Publication type:
    Article
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    Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial.

    Published in:
    PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0205368
    By:
    • Morales-Ramirez, Javier;
    • Bogner, Johannes R.;
    • Molina, Jean-Michel;
    • Lombaard, Johan;
    • Dicker, Ira B.;
    • Stock, David A.;
    • DeGrosky, Michelle;
    • Gartland, Margaret;
    • Pene Dumitrescu, Teodora;
    • Min, Sherene;
    • Llamoso, Cyril;
    • Joshi, Samit R.;
    • Lataillade, Max
    Publication type:
    Article
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    Preclinical Profile of the HIV-1 Maturation Inhibitor VH3739937.

    Published in:
    Viruses (1999-4915), 2024, v. 16, n. 10, p. 1508, doi. 10.3390/v16101508
    By:
    • McAuliffe, Brian;
    • Falk, Paul;
    • Chen, Jie;
    • Chen, Yan;
    • Sit, Sing-Yuen;
    • Swidorski, Jacob;
    • Hartz, Richard A.;
    • Xu, Li;
    • Venables, Brian;
    • Sin, Ny;
    • Meanwell, Nicholas A.;
    • Regueiro-Ren, Alicia;
    • Wensel, David;
    • Hanumegowda, Umesh;
    • Krystal, Mark
    Publication type:
    Article
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    Phase IIa Proof-of-Concept Evaluation of the Antiviral Efficacy, Safety, Tolerability, and Pharmacokinetics of the Next-Generation Maturation Inhibitor GSK3640254.

    Published in:
    Clinical Infectious Diseases, 2022, v. 75, n. 5, p. 786, doi. 10.1093/cid/ciab1065
    By:
    • Spinner, Christoph D;
    • Felizarta, Franco;
    • Rizzardini, Giuliano;
    • Philibert, Patrick;
    • Mitha, Essack;
    • Domingo, Pere;
    • Stephan, Christoph J;
    • DeGrosky, Michelle;
    • Bainbridge, Veronica;
    • Zhan, Joyce;
    • Dumitrescu, Teodora Pene;
    • Jeffrey, Jerry L;
    • Xu, Jianfeng;
    • Halliday, Fiona;
    • Gan, Jianjun;
    • Johnson, Mark;
    • Gartland, Martin;
    • Joshi, Samit R;
    • Lataillade, Max
    Publication type:
    Article
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    Bromodomain and extraterminal protein inhibitor JQ1 induces maturation arrest and disrupts the cytoplasmic organization in mouse oocytes under in vitro conditions.

    Published in:
    Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96687-z
    By:
    • Poojary, Keerthana Karunakar;
    • Kunhiraman, Jyolsna Ponnaratta;
    • Madhvacharya, Vanishree Vasave;
    • Kumari, Sandhya;
    • Krishna, Navami;
    • S, Suresh P;
    • K, Rajanikant G;
    • Mutalik, Srinivas;
    • Ghani, Nadeem Khan;
    • Kabekkodu, Shama Prasada;
    • Prasad, Thottethodi Subrahmanya Keshava;
    • Adiga, Satish Kumar;
    • Kalthur, Guruprasad
    Publication type:
    Article
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    JAK inhibitors differentially modulate B cell activation, maturation and function: A comparative analysis of five JAK inhibitors in an in-vitro B cell differentiation model and in patients with rheumatoid arthritis.

    Published in:
    Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2023.1087986
    By:
    • Frede, Natalie;
    • Lorenzetti, Raquel;
    • Hüppe, Janika M.;
    • Janowska, Iga;
    • Troilo, Arianna;
    • Schleyer, Marei-Theresa;
    • Venhoff, Ana C.;
    • Voll, Reinhard E.;
    • Thiel, Jens;
    • Venhoff, Nils;
    • Rizzi, Marta
    Publication type:
    Article
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