Works matching Lysosomes

Results: 5000

Lysosome-Targeted Biosensor for the Super-Resolution Imaging of Lysosome–Mitochondrion Interaction.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.865173

By:

Wang, Han;
Fang, Guiqian;
Chen, Huimin;
Hu, Maomao;
Cui, Yajuan;
Wang, Boyang;
Su, Yudong;
Liu, Yu;
Dong, Bo;
Shao, Xintian

Publication type:

Article

Lysosomes and lysosome-related organelles in immune responses.

Published in:

FEBS Open Bio, 2022, v. 12, n. 4, p. 678, doi. 10.1002/2211-5463.13388

By:

Watts, Colin

Publication type:

Article

The Dark Side of Lysosome-Related Organelles: Specialization of the Endocytic Pathway for Melanosome Biogenesis.

Published in:

Traffic, 2002, v. 3, n. 4, p. 237, doi. 10.1034/j.1600-0854.2002.030401.x

By:

Raposo, Graça;
Marks, Michael S

Publication type:

Article

The Biology of Lysosomes: From Order to Disorder.

Published in:

Biomedicines, 2023, v. 11, n. 1, p. 213, doi. 10.3390/biomedicines11010213

By:

Amaral, Olga;
Martins, Mariana;
Oliveira, Ana Rita;
Duarte, Ana Joana;
Mondragão-Rodrigues, Inês;
Macedo, M. Fátima

Publication type:

Article

Molecular Mechanism of Autophagosome–Lysosome Fusion in Mammalian Cells.

Published in:

Cells (2073-4409), 2024, v. 13, n. 6, p. 500, doi. 10.3390/cells13060500

By:

Ke, Po-Yuan

Publication type:

Article

Large-Scale, Wavelet-Based Analysis of Lysosomal Trajectories and Co-Movements of Lysosomes with Nanoparticle Cargos.

Published in:

Cells (2073-4409), 2022, v. 11, n. 2, p. 270, doi. 10.3390/cells11020270

By:

Polev, Konstantin;
Kolygina, Diana V.;
Kandere-Grzybowska, Kristiana;
Grzybowski, Bartosz A.

Publication type:

Article

Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport.

Published in:

Traffic, 2009, v. 10, n. 9, p. 1337, doi. 10.1111/j.1600-0854.2009.00945.x

By:

Qiangge Zhang;
Fubin Wang;
Jingli Cao;
Yidong Shen;
Qiongping Huang;
Lan Bao;
Xueliang Zhu

Publication type:

Article

Mannose-6-phosphate glycan for lysosomal targeting: various applications from enzyme replacement therapy to lysosome-targeting chimeras.

Published in:

Animal Cells & Systems, 2022, v. 26, n. 3, p. 84, doi. 10.1080/19768354.2022.2079719

By:

Seo, Jinho;
Oh, Doo-Byoung

Publication type:

Article

LYECs: lysosome-enhancing compounds as potential therapeutic approaches for Alzheimer disease.

Published in:

Autophagy, 2023, v. 19, n. 6, p. 1863, doi. 10.1080/15548627.2022.2131247

By:

Yin, Limin;
Zhou, Yu;
Liu, Hong;
Li, Yang

Publication type:

Article

Autophagic lysosome reformation in health and disease.

Published in:

Autophagy, 2023, v. 19, n. 5, p. 1378, doi. 10.1080/15548627.2022.2128019

By:

Nanayakkara, Randini;
Gurung, Rajendra;
Rodgers, Samuel J.;
Eramo, Matthew J.;
Ramm, Georg;
Mitchell, Christina A.;
McGrath, Meagan J.

Publication type:

Article

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.

Published in:

Autophagy, 2023, v. 19, n. 2, p. 692, doi. 10.1080/15548627.2022.2095834

By:

Carling, Phillippa J;
Ryan, Brent J;
McGuinness, William;
Kataria, Shikha;
Humble, Stewart W;
Milde, Stefan;
Duce, James A;
Kapadia, Nirav;
Zuercher, William J;
Davis, John B.;
Di Daniel, Elena;
Wade-Martins, Richard

Publication type:

Article

Degradative tubular lysosomes link pexophagy to starvation and early aging in C. elegans.

Published in:

Autophagy, 2022, v. 18, n. 7, p. 1522, doi. 10.1080/15548627.2021.1990647

By:

Dolese, Dominique A.;
Junot, Matthew P.;
Ghosh, Bhaswati;
Butsch, Tyler J.;
Johnson, Alyssa E.;
Bohnert, K. Adam

Publication type:

Article

Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P<sub>2</sub> is required for autophagic lysosome reformation and protection from skeletal muscle disease.

Published in:

Autophagy, 2021, v. 17, n. 5, p. 1287, doi. 10.1080/15548627.2021.1916195

By:

Eramo, Matthew J.;
Gurung, Rajendra;
Mitchell, Christina A.;
McGrath, Meagan J.

Publication type:

Article

Size of Azurophil Lysosomes of Human PMNs Determined by Stereological Morphometry.

Published in:

Ultrastructural Pathology, 2003, v. 27, n. 4, p. 261, doi. 10.1080/01913120309920

By:

Pippin, David J.;
Pippin, Kris D.

Publication type:

Article

COOH-terminal isoleucine of lysosome-associated membrane protein-1 is optimal for its efficient targeting to dense secondary lysosomes.

Published in:

Journal of Biochemistry, 2010, v. 148, n. 6, p. 669, doi. 10.1093/jb/mvq101

By:

Akasaki, Kenji;
Suenobu, Michihisa;
Mukaida, Maki;
Michihara, Akihiro;
Wada, Ikuo

Publication type:

Article

Better Together: Current Insights Into Phagosome-Lysosome Fusion.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.636078

By:

Nguyen, Jenny A.;
Yates, Robin M.

Publication type:

Article

Two-Photon Probes for Lysosomes and Mitochondria: Simultaneous Detection of Lysosomes and Mitochondria in Live Tissues by Dual-Color Two-Photon Microscopy Imaging.

Published in:

Chemistry - An Asian Journal, 2015, v. 10, n. 10, p. 2240, doi. 10.1002/asia.201500314

By:

Lim, Chang Su;
Hong, Seung Taek;
Ryu, Seong Shick;
Kang, Dong Eun;
Cho, Bong Rae

Publication type:

Article

Regulation of Autophagosome–Lysosome Fusion by Human Viral Infections.

Published in:

Pathogens, 2024, v. 13, n. 3, p. 266, doi. 10.3390/pathogens13030266

By:

Ke, Po-Yuan

Publication type:

Article

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.

Published in:

Small GTPases, 2013, v. 4, n. 1, p. 1, doi. 10.4161/sgtp.22349

By:

Bultema, Jarred J.;
Di Pietro, Santiago M.

Publication type:

Article

The lysosome as an imperative regulator of autophagy and cell death.

Published in:

2021

By:

Mahapatra, Kewal Kumar;
Mishra, Soumya Ranjan;
Behera, Bishnu Prasad;
Patil, Shankargouda;
Gewirtz, David A.;
Bhutia, Sujit Kumar

Publication type:

Literature Review

Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation.

Published in:

Liver International, 2013, v. 33, n. 7, p. 1056, doi. 10.1111/liv.12170

By:

Bieghs, Veerle;
Walenbergh, Sofie M. A.;
Hendrikx, Tim;
Gorp, Patrick J.;
Verheyen, Fons;
Olde Damink, Steven W.;
Masclee, Ad A.;
Koek, Ger H.;
Hofker, Marten H.;
Binder, Christoph J.;
Shiri‐Sverdlov, Ronit

Publication type:

Article

The Roles of Lysosomes in Inflammation and Autoimmune Diseases.

Published in:

International Reviews of Immunology, 2015, v. 34, n. 5, p. 415, doi. 10.3109/08830185.2014.936587

By:

Ge, Wei;
Li, Dongxu;
Gao, Yanpan;
Cao, Xuetao

Publication type:

Article

Lysosome-Mitochondrial Crosstalk in Cellular Stress and Disease.

Published in:

Antioxidants, 2025, v. 14, n. 2, p. 125, doi. 10.3390/antiox14020125

By:

Kiraly, Szilvia;
Stanley, Jack;
Eden, Emily R.

Publication type:

Article

Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2020, v. 48, n. 1, p. 824, doi. 10.1080/21691401.2020.1770266

By:

Chen, Mengge;
Ding, Yanpeng;
Ke, Yuan;
Zeng, Yifei;
Liu, Nuomin;
Zhong, Yahua;
Hua, Xinying;
Li, Zheng;
Xiong, Yudi;
Wu, Chaoyan;
Yu, Haijun

Publication type:

Article

Pallidin is a Component of a Multi-Protein Complex Involved in the Biogenesis of Lysosome-related Organelles.

Published in:

Traffic, 2002, v. 3, n. 9, p. 666, doi. 10.1034/j.1600-0854.2002.30908.x

By:

Moriyama, Kengo;
Bonifacino, Juan S.

Publication type:

Article

Secretory Lysosome Biogenesis in Cytotoxic T Lymphocytes from Normal and Chediak Higashi Syndrome Patients.

Published in:

Traffic, 2000, v. 1, n. 5, p. 435, doi. 10.1034/j.1600-0854.2000.010508.x

By:

Stinchcombe, Jane C.;
Page, Lesley J.;
Griffiths, Gillian M.

Publication type:

Article

The significance of targeting lysosomes in cancer immunotherapy.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1308070

By:

Yanxin Xu;
Bo Shao;
Yafeng Zhang

Publication type:

Article

Mitochondria–lysosome crosstalk in GBA1-associated Parkinson's disease.

Published in:

3 Biotech, 2022, v. 12, n. 9, p. 1, doi. 10.1007/s13205-022-03261-9

By:

Sahyadri, M.;
Nadiga, Abhishek P. R.;
Mehdi, Seema;
Mruthunjaya, K.;
Nayak, Pawan G.;
Parihar, Vipan K.;
Manjula, S. N.

Publication type:

Article

The role of lysosomes in cancer development and progression.

Published in:

Cell & Bioscience, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13578-020-00489-x

By:

Tang, Tao;
Yang, Ze-yu;
Wang, Di;
Yang, Xian-yan;
Wang, Jun;
Li, Lin;
Wen, Qian;
Gao, Lei;
Bian, Xiu-wu;
Yu, Shi-cang

Publication type:

Article

A new perspective on the regulation of glucose and cholesterol transport by mitochondria-lysosome contact sites.

Published in:

Frontiers in Physiology, 2024, p. 1, doi. 10.3389/fphys.2024.1431030

By:

Xiaolong Chen;
Chun Guang Li;
Xian Zhou;
Minghua Zhu;
Jing Jin;
Ping Wang

Publication type:

Article

Effects of sex hormones on the development of giant lysosomes in the proximal tubules of DBA/2Cr mouse kidney.

Published in:

Journal of Anatomy, 2003, v. 202, n. 5, p. 445, doi. 10.1046/j.1469-7580.2003.00173.x

By:

Yabuki, Akira;
Suzuki, Syusaku;
Matsumoto, Mitsuharu;
Nishinakagawa, Hayao

Publication type:

Article

Transcription factor EB agonists from natural products for treating human diseases with impaired autophagy-lysosome pathway.

Published in:

Chinese Medicine, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13020-020-00402-1

By:

Xu, Jie;
Zhang, Xiao-Qi;
Zhang, Zaijun

Publication type:

Article

Novel strategies targeting mitochondria-lysosome contact sites for the treatment of neurological diseases.

Published in:

2025

By:

Xie, Yinyin;
Sun, Wenlin;
Han, Aoya;
Zhou, Xinru;
Zhang, Shijie;
Shen, Changchang;
Xie, Yi;
Wang, Cui;
Xie, Nanchang

Publication type:

Literature Review

Enhancing Astrocytic Lysosome Biogenesis Facilitates Aβ Clearance and Attenuates Amyloid Plaque Pathogenesis.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 29, p. 9607, doi. 10.1523/JNEUROSCI.3788-13.2014

By:

Qingli Xiao;
Ping Yan;
Xiucui Ma;
Haiyan Liu;
Perez, Ronaldo;
Zhu, Alec;
Gonzales, Ernesto;
Burchett, Jack M.;
Schuler, Dorothy R.;
Cirrito, John R.;
Diwan, Abhinav;
Jin-Moo Lee

Publication type:

Article

KIF2ß, a new kinesin superfamily protein in non-neuronal cells, is associated with lysosomes and may be implicated in their centrifugal translocation.

Published in:

EMBO Journal, 1998, v. 17, n. 20, p. 5855, doi. 10.1093/emboj/17.20.5855

By:

Santama, Niovi;
Krijnse-Locker, Jacomine;
Griffiths, Gareth;
Noda, Yasuko;
Hirokawa, Nobutaka;
Dotti, Carlos G.

Publication type:

Article

syk protein tyrosine kinase regulates Fc receptor ?-chain-mediated transport to lysosomes.

Published in:

EMBO Journal, 1998, v. 17, n. 16, p. 4606, doi. 10.1093/emboj/17.16.4606

By:

Bonnerot, Christian;
Briken, Volker;
Brachet, Valérie;
Lankar, Danielle;
Cassard, Sylvanie;
Jabri, Bana;
Amigorena, Sebastian

Publication type:

Article

Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers.

Published in:

2017

By:

Dykes, Samantha S.;
Steffan, Joshua J.;
Cardelli, James A.

Publication type:

journal article

Loss of the interferon-γ-inducible regulatory immunity-related GTPase (IRG), Irgm1, causes activation of effector IRG proteins on lysosomes, damaging lysosomal function and predicting the dramatic susceptibility of Irgm1-deficient mice to infection.

Published in:

BMC Biology, 2016, v. 14, p. 1, doi. 10.1186/s12915-016-0255-4

By:

Maric-Biresev, Jelena;
Hunn, Julia P.;
Krut, Oleg;
Helms, J. Bernd;
Martens, Sascha;
Howard, Jonathan C.

Publication type:

Article

Pleiotropic role of Drosophila phosphoribosyl pyrophosphate synthetase in autophagy and lysosome homeostasis.

Published in:

PLoS Genetics, 2019, v. 15, n. 9, p. 1, doi. 10.1371/journal.pgen.1008376

By:

Delos Santos, Keemo;
Kim, Minhee;
Yergeau, Christine;
Jean, Steve;
Moon, Nam-Sung

Publication type:

Article

Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis.

Published in:

PLoS Genetics, 2018, v. 14, n. 11, p. 1, doi. 10.1371/journal.pgen.1007772

By:

Morris, Caitlin;
Foster, Olivia K.;
Handa, Simran;
Peloza, Kimberly;
Voss, Laura;
Somhegyi, Hannah;
Jian, Youli;
Vo, My Van;
Harp, Marie;
Rambo, Fiona M.;
Yang, Chonglin;
Hermann, Greg J.

Publication type:

Article

Fluorogenic Rhodamine Probes with Pyrrole Substitution Enables STED and Lifetime Imaging of Lysosomes in Live Cells.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 15, p. 1, doi. 10.1002/chem.202303707

By:

Zhou, Ying;
Wang, Qiuping;
Chanmungkalakul, Supphachok;
Wu, Xia;
Xiao, Hui;
Miao, Rong;
Liu, Xiaogang;
Fang, Yu

Publication type:

Article

Lysosome Interference Enabled by Proton‐Driven Dynamic Assembly of DNA Nanoframeworks inside Cells.

Published in:

Angewandte Chemie, 2022, v. 134, n. 36, p. 1, doi. 10.1002/ange.202207770

By:

Dong, Yuhang;
Li, Feng;
Lv, Zhaoyue;
Li, Shuai;
Yuan, Meihe;
Song, Nachuan;
Liu, Jinqiao;
Yang, Dayong

Publication type:

Article

A pH‐Driven Small‐Molecule Nanotransformer Hijacks Lysosomes and Overcomes Autophagy‐Induced Resistance in Cancer.

Published in:

Angewandte Chemie, 2022, v. 134, n. 35, p. 1, doi. 10.1002/ange.202204567

By:

Ma, Zhao;
Lin, Kai;
Tang, Menghuan;
Ramachandran, Mythili;
Qiu, Reng;
Li, Jin;
Solano, Lucas N.;
Huang, Yanyu;
De Souza, Cristabelle;
Abou‐Adas, Sara;
Xiang, Bai;
Zhang, Lanwei;
Li, Minyong;
Li, Yuanpei

Publication type:

Article

An Acid‐Regulated Self‐Blinking Fluorescent Probe for Resolving Whole‐Cell Lysosomes with Long‐Term Nanoscopy.

Published in:

Angewandte Chemie, 2022, v. 134, n. 21, p. 1, doi. 10.1002/ange.202202961

By:

Qiao, Qinglong;
Liu, Wenjuan;
Chen, Jie;
Wu, Xia;
Deng, Fei;
Fang, Xiangning;
Xu, Ning;
Zhou, Wei;
Wu, Shaowei;
Yin, Wenting;
Liu, Xiaogang;
Xu, Zhaochao

Publication type:

Article

Robust Packing of a Self‐Assembling Iridium Complex via Endocytic Trafficking for Long‐Term Lysosome Tracking.

Published in:

Angewandte Chemie, 2021, v. 133, n. 14, p. 7675, doi. 10.1002/ange.202015913

By:

Jin, Chengzhi;
Li, Guanying;
Wu, Xia;
Liu, Jiangping;
Wu, Weijun;
Chen, Yazhou;
Sasaki, Toshio;
Chao, Hui;
Zhang, Ye

Publication type:

Article

Light‐Induced Self‐Escape of Spherical Nucleic Acid from Endo/Lysosome for Efficient Non‐Cationic Gene Delivery.

Published in:

Angewandte Chemie, 2020, v. 132, n. 43, p. 19330, doi. 10.1002/ange.202006890

By:

Shi, Leilei;
Wu, Wenbo;
Duan, Yukun;
Xu, Li;
Xu, Yingying;
Hou, Lidan;
Meng, Xiangjun;
Zhu, Xinyuan;
Liu, Bin

Publication type:

Article

Characterization of the endolysosomal system in human chordoma cell lines: is there a role of lysosomes in chemoresistance of this rare bone tumor?

Published in:

Histochemistry & Cell Biology, 2018, v. 150, n. 1, p. 83, doi. 10.1007/s00418-018-1673-x

By:

Kolb-Lenz, Dagmar;
Fuchs, Robert;
Lohberger, Birgit;
Heitzer, Ellen;
Meditz, Katharina;
Pernitsch, Dominique;
Pritz, Elisabeth;
Groselj-Strele, Andrea;
Leithner, Andreas;
Liegl-Atzwanger, Bernadette;
Rinner, Beate

Publication type:

Article

Lysosomes in iron metabolism, ageing and apoptosis.

Published in:

Histochemistry & Cell Biology, 2008, v. 129, n. 4, p. 389, doi. 10.1007/s00418-008-0394-y

By:

Kurz, Tino;
Terman, Alexei;
Gustafsson, Bertil;
Brunk, Ulf

Publication type:

Article

Lysosome function in glomerular health and disease.

Published in:

Cell & Tissue Research, 2021, v. 385, n. 2, p. 371, doi. 10.1007/s00441-020-03375-7

By:

Meyer-Schwesinger, Catherine

Publication type:

Article

Effect of solute hydrogen bonding capacity on osmotic stability of lysosomes.

Published in:

Biochemistry (00062979), 2009, v. 74, n. 12, p. 1363, doi. 10.1134/S0006297909120104

By:

Shu-Jing Hao;
Jun-Fang Hou;
Guo-Jiang Zhang

Publication type:

Article