Works matching Lysosome

Results: 5000

Lysosomes and lysosome-related organelles in immune responses.

Published in:

FEBS Open Bio, 2022, v. 12, n. 4, p. 678, doi. 10.1002/2211-5463.13388

By:

Watts, Colin

Publication type:

Article

Lysosome-Targeted Biosensor for the Super-Resolution Imaging of Lysosome–Mitochondrion Interaction.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.865173

By:

Wang, Han;
Fang, Guiqian;
Chen, Huimin;
Hu, Maomao;
Cui, Yajuan;
Wang, Boyang;
Su, Yudong;
Liu, Yu;
Dong, Bo;
Shao, Xintian

Publication type:

Article

Size of Azurophil Lysosomes of Human PMNs Determined by Stereological Morphometry.

Published in:

Ultrastructural Pathology, 2003, v. 27, n. 4, p. 261, doi. 10.1080/01913120309920

By:

Pippin, David J.;
Pippin, Kris D.

Publication type:

Article

Better Together: Current Insights Into Phagosome-Lysosome Fusion.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.636078

By:

Nguyen, Jenny A.;
Yates, Robin M.

Publication type:

Article

Mannose-6-phosphate glycan for lysosomal targeting: various applications from enzyme replacement therapy to lysosome-targeting chimeras.

Published in:

Animal Cells & Systems, 2022, v. 26, n. 3, p. 84, doi. 10.1080/19768354.2022.2079719

By:

Seo, Jinho;
Oh, Doo-Byoung

Publication type:

Article

LYECs: lysosome-enhancing compounds as potential therapeutic approaches for Alzheimer disease.

Published in:

Autophagy, 2023, v. 19, n. 6, p. 1863, doi. 10.1080/15548627.2022.2131247

By:

Yin, Limin;
Zhou, Yu;
Liu, Hong;
Li, Yang

Publication type:

Article

Autophagic lysosome reformation in health and disease.

Published in:

Autophagy, 2023, v. 19, n. 5, p. 1378, doi. 10.1080/15548627.2022.2128019

By:

Nanayakkara, Randini;
Gurung, Rajendra;
Rodgers, Samuel J.;
Eramo, Matthew J.;
Ramm, Georg;
Mitchell, Christina A.;
McGrath, Meagan J.

Publication type:

Article

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.

Published in:

Autophagy, 2023, v. 19, n. 2, p. 692, doi. 10.1080/15548627.2022.2095834

By:

Carling, Phillippa J;
Ryan, Brent J;
McGuinness, William;
Kataria, Shikha;
Humble, Stewart W;
Milde, Stefan;
Duce, James A;
Kapadia, Nirav;
Zuercher, William J;
Davis, John B.;
Di Daniel, Elena;
Wade-Martins, Richard

Publication type:

Article

Degradative tubular lysosomes link pexophagy to starvation and early aging in C. elegans.

Published in:

Autophagy, 2022, v. 18, n. 7, p. 1522, doi. 10.1080/15548627.2021.1990647

By:

Dolese, Dominique A.;
Junot, Matthew P.;
Ghosh, Bhaswati;
Butsch, Tyler J.;
Johnson, Alyssa E.;
Bohnert, K. Adam

Publication type:

Article

Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P<sub>2</sub> is required for autophagic lysosome reformation and protection from skeletal muscle disease.

Published in:

Autophagy, 2021, v. 17, n. 5, p. 1287, doi. 10.1080/15548627.2021.1916195

By:

Eramo, Matthew J.;
Gurung, Rajendra;
Mitchell, Christina A.;
McGrath, Meagan J.

Publication type:

Article

Regulation of Autophagosome–Lysosome Fusion by Human Viral Infections.

Published in:

Pathogens, 2024, v. 13, n. 3, p. 266, doi. 10.3390/pathogens13030266

By:

Ke, Po-Yuan

Publication type:

Article

Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport.

Published in:

Traffic, 2009, v. 10, n. 9, p. 1337, doi. 10.1111/j.1600-0854.2009.00945.x

By:

Qiangge Zhang;
Fubin Wang;
Jingli Cao;
Yidong Shen;
Qiongping Huang;
Lan Bao;
Xueliang Zhu

Publication type:

Article

The Dark Side of Lysosome-Related Organelles: Specialization of the Endocytic Pathway for Melanosome Biogenesis.

Published in:

Traffic, 2002, v. 3, n. 4, p. 237, doi. 10.1034/j.1600-0854.2002.030401.x

By:

Raposo, Graça;
Marks, Michael S

Publication type:

Article

The lysosome as an imperative regulator of autophagy and cell death.

Published in:

2021

By:

Mahapatra, Kewal Kumar;
Mishra, Soumya Ranjan;
Behera, Bishnu Prasad;
Patil, Shankargouda;
Gewirtz, David A.;
Bhutia, Sujit Kumar

Publication type:

Literature Review

The Biology of Lysosomes: From Order to Disorder.

Published in:

Biomedicines, 2023, v. 11, n. 1, p. 213, doi. 10.3390/biomedicines11010213

By:

Amaral, Olga;
Martins, Mariana;
Oliveira, Ana Rita;
Duarte, Ana Joana;
Mondragão-Rodrigues, Inês;
Macedo, M. Fátima

Publication type:

Article

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles.

Published in:

Small GTPases, 2013, v. 4, n. 1, p. 1, doi. 10.4161/sgtp.22349

By:

Bultema, Jarred J.;
Di Pietro, Santiago M.

Publication type:

Article

Two-Photon Probes for Lysosomes and Mitochondria: Simultaneous Detection of Lysosomes and Mitochondria in Live Tissues by Dual-Color Two-Photon Microscopy Imaging.

Published in:

Chemistry - An Asian Journal, 2015, v. 10, n. 10, p. 2240, doi. 10.1002/asia.201500314

By:

Lim, Chang Su;
Hong, Seung Taek;
Ryu, Seong Shick;
Kang, Dong Eun;
Cho, Bong Rae

Publication type:

Article

COOH-terminal isoleucine of lysosome-associated membrane protein-1 is optimal for its efficient targeting to dense secondary lysosomes.

Published in:

Journal of Biochemistry, 2010, v. 148, n. 6, p. 669, doi. 10.1093/jb/mvq101

By:

Akasaki, Kenji;
Suenobu, Michihisa;
Mukaida, Maki;
Michihara, Akihiro;
Wada, Ikuo

Publication type:

Article

Molecular Mechanism of Autophagosome–Lysosome Fusion in Mammalian Cells.

Published in:

Cells (2073-4409), 2024, v. 13, n. 6, p. 500, doi. 10.3390/cells13060500

By:

Ke, Po-Yuan

Publication type:

Article

Large-Scale, Wavelet-Based Analysis of Lysosomal Trajectories and Co-Movements of Lysosomes with Nanoparticle Cargos.

Published in:

Cells (2073-4409), 2022, v. 11, n. 2, p. 270, doi. 10.3390/cells11020270

By:

Polev, Konstantin;
Kolygina, Diana V.;
Kandere-Grzybowska, Kristiana;
Grzybowski, Bartosz A.

Publication type:

Article

Lysosome-derived biomarkers for predicting survival outcome in acute myeloid leukemia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03302-8

By:

Li, Gongchang;
Miao, Yangyang;
Yuan, Fang;
Zhang, Weiran;
Wu, Yali;
Zhu, Liqiang

Publication type:

Article

Lysosome-Targeted Single Fluorescence Probe for Two-Channel Imaging Intracellular SO2 and Biothiols.

Published in:

Molecules, 2019, v. 24, n. 3, p. 618, doi. 10.3390/molecules24030618

By:

Wang, Yue;
Liu, Li;
Zhou, Xian-Li;
Wu, Ming-Yu

Publication type:

Article

Heat Acclimation Regulates the Autophagy-Lysosome Function to Protect Against Heat Stroke-Induced Brain Injury in Mice.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 41, n. 1, p. 101, doi. 10.1159/000455979

By:

Yi, Junfeng;
He, Genlin;
Yang, Ju;
Luo, Zhen;
Yang, Xuesen;
Luo, Xue

Publication type:

Article

Oxidative Stress Triggers Ca-Dependent Lysosome Trafficking and Activation of Acid Sphingomyelinase.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2012, v. 30, n. 4, p. 815, doi. 10.1159/000341460

By:

Li, Xiang;
Gulbins, Erich;
Zhang, Yang

Publication type:

Article

The Roles of Lysosomes in Inflammation and Autoimmune Diseases.

Published in:

International Reviews of Immunology, 2015, v. 34, n. 5, p. 415, doi. 10.3109/08830185.2014.936587

By:

Ge, Wei;
Li, Dongxu;
Gao, Yanpan;
Cao, Xuetao

Publication type:

Article

Intracellular Survival of Biofilm-Forming MRSA OJ-1 by Escaping from the Lysosome and Autophagosome in J774A Cells Cultured in Overdosed Vancomycin.

Published in:

Microorganisms, 2022, v. 10, n. 2, p. N.PAG, doi. 10.3390/microorganisms10020348

By:

Jimi, Shiro;
Yoshimura, Michinobu;
Mashima, Kota;
Ueda, Yutaka;
Miyazaki, Motoyasu;
Saparov, Arman

Publication type:

Article

Presence of TRPV3 in macrophage lysosomes helps in skin wound healing against bacterial infection.

Published in:

Experimental Dermatology, 2023, v. 32, n. 1, p. 60, doi. 10.1111/exd.14683

By:

Sahu, Ram P.;
Goswami, Chandan

Publication type:

Article

The tryptophan-aspartate (WD) repeat domain of bovine Coronin-1A promotes mycobacterial survival by inhibiting calcium signaling-mediated phagosome-lysosome fusion.

Published in:

Veterinary Research, 2025, v. 56, n. 1, p. 1, doi. 10.1186/s13567-025-01471-6

By:

Yang, Jing;
Li, Zhunan;
Li, Aicong;
Liu, Yayi;
Zhang, Xinyan;
Zhang, Yong;
Gao, Yuanpeng

Publication type:

Article

Lysosome: as a proposed target for rose bengal in inducing cell death in melanoma cells.

Published in:

Iranian Journal of Medical Hypotheses & Ideas, 2008, v. 2, p. 1

By:

Mousavi, Seyed Hadi;
Moosavi, Seyed Hamed

Publication type:

Article

Pathogenic mechanisms in lysosomal disease: a reappraisal of the role of the lysosome.

Published in:

Acta Paediatrica, 2007, p. 26, doi. 10.1111/j.1651-2227.2007.00202.x

By:

Walkley, Steven U.

Publication type:

Article

Regulating Secretory Lysosomes.

Published in:

Journal of Biochemistry, 2006, v. 140, n. 1, p. 7, doi. 10.1093/jb/mvj126

By:

Holt, Oliver J.;
Gallo, Federico;
Griffiths, Gillian M.

Publication type:

Article

Inhibition of Weak-Base Amine-Induced Lysis of Lysosomes by Cytosol1.

Published in:

Journal of Biochemistry, 2002, v. 132, n. 4, p. 529, doi. 10.1093/oxfordjournals.jbchem.a003253

By:

Arai, Kunizo;
Yasuda, Nobuhiro;
Isohashi, Fumihide;
Okamoto, Kazuki;
Ohkuma, Shoji

Publication type:

Article

Lysosomal Cysteine Protease, Cathepsin B, Is Targeted to Lysosomes by the Mannose 6-Phosphate-Independent Pathway in Rat Hepatocytes: Site-Specific Phosphorylation in Oligosaccharides of the Proregion1.

Published in:

Journal of Biochemistry, 2000, v. 128, n. 1, p. 39, doi. 10.1093/oxfordjournals.jbchem.a022728

By:

Tanaka, Yoshitaka;
Tanaka, Rie;
Kawabata, Takahiro;
Noguchi, Youichiro;
Himeno, Masaru

Publication type:

Article

Human Parathyroid Hormone (1–34) Transiently Increases the Excretion of Lysosomal Enzymes into Urine and the Size of Renal Lysosomes.

Published in:

Journal of Biochemistry, 1999, v. 126, n. 3, p. 485, doi. 10.1093/oxfordjournals.jbchem.a022477

By:

Iwata, Takanori;
Sakai, Kentaro;
Hori, Masayuki;
Uchida, Shunya;
Towatari, Takae;
Kido, Hiroshi

Publication type:

Article

Disintegration of Lysosomes Mediated by GTPγS-Treated Cytosol Possible Involvement of Phospholipases1.

Published in:

Journal of Biochemistry, 1998, v. 123, n. 4, p. 630, doi. 10.1093/oxfordjournals.jbchem.a021984

By:

Sai, Yoshimichi;
Matsuda, Tomoko;
Arai, Kunizo;
Ohkuma, Shoji

Publication type:

Article

Biosynthetic Transport of a Major Lysosome-Associated Membrane Glycoprotein 2, Lamp-2: A Significant Fraction of Newly Synthesized Lamp-2 Is Delivered to Lysosomes by Way of Early Endosomes.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 6, p. 1088, doi. 10.1093/oxfordjournals.jbchem.a021526

By:

Akasaki, Kenji;
Michihara, Akihiro;
Fujiwara, Yoshiteru;
Mibuka, Kouichi;
Tsuji, Hiroshi

Publication type:

Article

Antiretroviral treatment reveals a novel role for lysosomes in oligodendrocyte maturation.

Published in:

Journal of Neurochemistry, 2023, v. 165, n. 5, p. 722, doi. 10.1111/jnc.15773

By:

Festa, Lindsay K.;
Clyde, Abigail E.;
Long, Caela C.;
Roth, Lindsay M.;
Grinspan, Judith B.;
Jordan‐Sciutto, Kelly L.

Publication type:

Article

Logic‐Gated DNA Intelligent Nanorobots for Cellular Lysosome Interference and Enhanced Therapeutics.

Published in:

Angewandte Chemie, 2025, v. 137, n. 15, p. 1, doi. 10.1002/ange.202423004

By:

Wang, Qiwei;
Chang, Ruixue;
Li, Xiuping;
Zhang, Ying;
Fan, Xiangshan;
Shi, Lili;
Li, Tao

Publication type:

Article

Bioimaging of Lysosomes with a BODIPY pH-Dependent Fluorescent Probe.

Published in:

Molecules, 2022, v. 27, n. 22, p. 8065, doi. 10.3390/molecules27228065

By:

Gonçalves, Raquel C. R.;
Belmonte-Reche, Efres;
Pina, João;
Costa da Silva, Milene;
Pinto, Sónia C. S.;
Gallo, Juan;
Costa, Susana P. G.;
Raposo, M. Manuela M.

Publication type:

Article

Application of meso -CF 3 -Fluorophore BODIPY with Phenyl and Pyrazolyl Substituents for Lifetime Visualization of Lysosomes.

Published in:

Molecules, 2022, v. 27, n. 15, p. 5018, doi. 10.3390/molecules27155018

By:

Trukhan, Irina S.;
Tomilin, Denis N.;
Dremina, Nataliya N.;
Sobenina, Lyubov N.;
Shurygin, Michael G.;
Petrushenko, Konstantin B.;
Petrushenko, Igor K.;
Trofimov, Boris A.;
Shurygina, Irina A.

Publication type:

Article

Within the Ischemic Penumbra, Sub-Cellular Compartmentalization of Heat Shock Protein 70 Overlaps with Autophagy Proteins and Fails to Merge with Lysosomes.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3122, doi. 10.3390/molecules27103122

By:

Mastroiacovo, Federica;
Biagioni, Francesca;
Lenzi, Paola;
Lazzeri, Gloria;
Ferrucci, Michela;
Puglisi-Allegra, Stefano;
Frati, Alessandro;
Nicoletti, Ferdinando;
Fornai, Francesco

Publication type:

Article

Lysosome Inhibitors Enhance the Chemotherapeutic Activity of Doxorubicin in HepG2 Cells.

Published in:

Chemotherapy (0009-3157), 2017, v. 62, n. 2, p. 85, doi. 10.1159/000448802

By:

Li, Yuyin;
Sun, Yuejun;
Jing, Lifang;
Wang, Jianjun;
Yan, Yali;
Feng, Yajuan;
Zhang, Yueying;
Liu, Zhenxing;
Ma, Long;
Diao, Aipo

Publication type:

Article

Transport of N-acetylchitooligosaccharides and fluorescent N-acetylchitooligosaccharide analogs into rat liver lysosomes.

Published in:

Glycobiology, 2024, v. 34, n. 2, p. 1, doi. 10.1093/glycob/cwad099

By:

Bouzidi, Younès;
Bosco, Michaël;
Gao, Haifei;
Pradeau, Stéphanie;
Matheron, Lucrèce;
Chantret, Isabelle;
Busca, Patricia;
Fort, Sébastien;
Gravier-Pelletier, Christine;
Moore, Stuart E H

Publication type:

Article

Deciphering tuberculosis: lysosome-centric insights into pathogenesis and therapies.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1582037

By:

Bao, Cui;
Zhang, Yuanyuan;
Feng, Jiao;
Hong, Xiuwen;
Gao, Nan;
Feng, Ganzhu

Publication type:

Article

Enhancing Astrocytic Lysosome Biogenesis Facilitates Aβ Clearance and Attenuates Amyloid Plaque Pathogenesis.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 29, p. 9607, doi. 10.1523/JNEUROSCI.3788-13.2014

By:

Qingli Xiao;
Ping Yan;
Xiucui Ma;
Haiyan Liu;
Perez, Ronaldo;
Zhu, Alec;
Gonzales, Ernesto;
Burchett, Jack M.;
Schuler, Dorothy R.;
Cirrito, John R.;
Diwan, Abhinav;
Jin-Moo Lee

Publication type:

Article

Pitfalls in methods to study colocalization of nanoparticles in mouse macrophage lysosomes.

Published in:

Journal of Nanobiotechnology, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12951-022-01670-9

By:

Moreno-Echeverri, Aura Maria;
Susnik, Eva;
Vanhecke, Dimitri;
Taladriz-Blanco, Patricia;
Balog, Sandor;
Petri-Fink, Alke;
Rothen-Rutishauser, Barbara

Publication type:

Article

Protecting cells by protecting their vulnerable lysosomes: Identification of a new mechanism for preserving lysosomal functional integrity upon oxidative stress.

Published in:

PLoS Genetics, 2017, v. 13, n. 2, p. 1, doi. 10.1371/journal.pgen.1006603

By:

Pascua-Maestro, Raquel;
Diez-Hermano, Sergio;
Lillo, Concepción;
Ganfornina, Maria D.;
Sanchez, Diego

Publication type:

Article

The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function.

Published in:

PLoS Genetics, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pgen.1006036

By:

Cai, Weili;
Wei, Youheng;
Jarnik, Michal;
Reich, John;
Lilly, Mary A.

Publication type:

Article

Thiol-specific fluorogenic agent for live cell non-protein thiol imaging in lysosomes.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 24, p. 6463, doi. 10.1007/s00216-019-02026-3

By:

Alqahtani, Yahya;
Wang, Shenggang;
Najmi, Asim;
Huang, Yue;
Guan, Xiangming

Publication type:

Article

Characterization of the endolysosomal system in human chordoma cell lines: is there a role of lysosomes in chemoresistance of this rare bone tumor?

Published in:

Histochemistry & Cell Biology, 2018, v. 150, n. 1, p. 83, doi. 10.1007/s00418-018-1673-x

By:

Kolb-Lenz, Dagmar;
Fuchs, Robert;
Lohberger, Birgit;
Heitzer, Ellen;
Meditz, Katharina;
Pernitsch, Dominique;
Pritz, Elisabeth;
Groselj-Strele, Andrea;
Leithner, Andreas;
Liegl-Atzwanger, Bernadette;
Rinner, Beate

Publication type:

Article