Works matching Knockout genetics and knockout mice

Results: 296

Enhanced ghrelin expression and subsequent acid secretion in mice with genetic H(2)-receptor knockout.

Published in:

2007

By:

Arakawa M;
Suzuki H;
Minegishi Y;
Fukushima Y;
Masaoka T;
Ishikawa T;
Hosoda H;
Kangawa K;
Hibi T;
Arakawa, Mamoru;
Suzuki, Hidekazu;
Minegishi, Yuriko;
Fukushima, Yasushi;
Masaoka, Tatsuhiro;
Ishikawa, Takashi;
Hosoda, Hiroshi;
Kangawa, Kenji;
Hibi, Toshifumi

Publication type:

journal article

Enhanced ghrelin expression and subsequent acid secretion in mice with genetic H<sub>2</sub>-receptor knockout.

Published in:

Journal of Gastroenterology, 2007, v. 42, n. 9, p. 711, doi. 10.1007/s00535-007-2084-2

By:

Arakawa, Mamoru;
Suzuki, Hidekazu;
Minegishi, Yuriko;
Fukushima, Yasushi;
Masaoka, Tatsuhiro;
Ishikawa, Takashi;
Hosoda, Hiroshi;
Kangawa, Kenji;
Hibi, Toshifumi

Publication type:

Article

Acquisition and extinction of a conditioned passive avoidance reflex in mice with genetic knockout of monoamine oxidase A.

Published in:

Neuroscience & Behavioral Physiology, 2006, v. 36, n. 4, p. 335, doi. 10.1007/s11055-006-0022-z

By:

N. Dubrovina;
N. Popova;
M. Gilinskii;
R. Tomilenko;
I. Seif

Publication type:

Article

Behavioral Characteristics of Mice with Genetic Knockout of Monoamine Oxidase Type A.

Published in:

Neuroscience & Behavioral Physiology, 2001, v. 31, n. 6, p. 597, doi. 10.1023/A:1012364910091

By:

Popova, N.;
Skrinskaya, Yu.;
Amstislavskaya, T.;
Vishnivetskaya, G.;
Seif, I.;
de Meier, E.

Publication type:

Article

Analyses of Glutathione Reductase Hypomorphic Mice Indicate a Genetic Knockout.

Published in:

Toxicological Sciences, 2004, v. 82, n. 2, p. 367, doi. 10.1093/toxsci/kfh268

By:

Rogers, Lynette K.;
Tamura, Toshiya;
Rogers, Bryan J.;
Welty, Stephen E.;
Hansen, Thomas N.;
Smith, Charles V.

Publication type:

Article

Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements.

Published in:

2010

By:

Sanders AM;
Stehle JR Jr;
Blanks MJ;
Riedlinger G;
Kim-Shapiro JW;
Monjazeb AM;
Adams JM;
Willingham MC;
Cui Z;
Sanders, Anne M;
Stehle, John R Jr;
Blanks, Michael J;
Riedlinger, Gregory;
Kim-Shapiro, Jung W;
Monjazeb, Arta M;
Adams, Jonathan M;
Willingham, Mark C;
Cui, Zheng

Publication type:

journal article

Human Genetic Disorders and Knockout Mice Deficient in Glycosaminoglycan.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/495764

By:

Shuji Mizumoto;
Shuhei Yamada;
Kazuyuki Sugahara

Publication type:

Article

敲除NDRG2 基因的AD模型小鼠的构建与鉴定.

Published in:

Progress in Modern Biomedicine, 2017, v. 17, n. 6, p. 1020, doi. 10.13241/j.cnki.pmb.2017.06.005

By:

陶亮;
唐海利;
张伟东;
李燕;
熊利泽

Publication type:

Article

敲除 NDRG2 基因的 AD 模型小鼠的构建与鉴定.

Published in:

Progress in Modern Biomedicine, 2017, v. 17, n. 4, p. 1020, doi. 10.13241/j.cnki.pmb.2017.06.005

By:

陶亮;
唐海利;
张伟东;
李燕;
熊利泽

Publication type:

Article

The Sanger Mouse Genetics Programme: High Throughput Characterisation of Knockout Mice.

Published in:

Acta Ophthalmologica (1755375X), 2011, v. 89, p. 0, doi. 10.1111/j.1755-3768.2011.4451.x

By:

GARDIN, A;
WHITE, J

Publication type:

Article

The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice.

Published in:: Acta Ophthalmologica (1755375X), 2010, v. 88, p. 0, doi. 10.1111/j.1755-3768.2010.4142.x
Publication type:: Article

Lack of genotype effect on D1, D2 receptors and dopamine transporter binding in triple MOP-, DOP-, and KOP-opioid receptor knockout mice of three different genetic backgrounds.

Published in:

Synapse, 2010, v. 64, n. 7, p. 520, doi. 10.1002/syn.20757

By:

Yoo, Ji-hoon;
Bailey, Alexis;
Ansonoff, Micheal;
Pintar, John E.;
Matifas, Audrey;
Kieffer, Brigitte L.;
Kitchen, Ian

Publication type:

Article

Exaggerated behavioral phenotypes in Fmr1/Fxr2 double knockout mice reveal a functional genetic interaction between Fragile X-related proteins.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 12, p. 1984, doi. 10.1093/hmg/ddl121

By:

Spencer, Corinne M.;
Serysheva, Ekaterina;
Yuva-Paylor, Lisa A.;
Oostra, Ben A.;
Nelson, David L.;
Paylor, Richard

Publication type:

Article

The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition

Published in:

Pharmaceutical Research, 2017, v. 34, n. 12, p. 2498, doi. 10.1007/s11095-017-2220-5

By:

Price, Daniel;
Luscombe, Chris;
Eddershaw, Peter;
Edwards, Chris;
Gumbleton, Mark

Publication type:

Article

iPLAβ Knockout Mouse, a Genetic Model for Progressive Human Motor Disorders, Develops Age-Related Neuropathology.

Published in:

Neurochemical Research, 2014, v. 39, n. 8, p. 1522, doi. 10.1007/s11064-014-1342-y

By:

Blanchard, Helene;
Taha, Ameer;
Cheon, Yewon;
Kim, Hyung-Wook;
Turk, John;
Rapoport, Stanley

Publication type:

Article

FKBP5 Moderates Alcohol Withdrawal Severity: Human Genetic Association and Functional Validation in Knockout Mice.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 8, p. 2029, doi. 10.1038/npp.2014.55

By:

Huang, Ming-Chyi;
Schwandt, Melanie L;
Chester, Julia A;
Kirchhoff, Aaron M;
Kao, Chung-Feng;
Liang, Tiebing;
Tapocik, Jenica D;
Ramchandani, Vijay A;
George, David T;
Hodgkinson, Colin A;
Goldman, David;
Heilig, Markus

Publication type:

Article

Why Hepatic CYP2E1-Elevation by Itself Is Insufficient for Inciting NAFLD/NASH: Inferences from Two Genetic Knockout Mouse Models.

Published in:

Biology (2079-7737), 2020, v. 9, n. 12, p. 419, doi. 10.3390/biology9120419

By:

Correia, Maria Almira;
Kwon, Doyoung

Publication type:

Article

Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice.

Published in:

PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0301328

By:

Lyon, Gholson J.;
Longo, Joseph;
Garcia, Andrew;
Inusa, Fatima;
Marchi, Elaine;
Shi, Daniel;
Dörfel, Max;
Arnesen, Thomas;
Aldabe, Rafael;
Lyons, Scott;
Nashat, Melissa A.;
Bolton, David

Publication type:

Article

Proinsulin 2 knockout NOD mice: a model for genetic variation of insulin gene expression in type 1 diabetes.

Published in:

2002

By:

Dubois-Lafforgue, Danièle;
Mogenet, Laurent;
Thébault, Karine;
Jami, Jacques;
Krief, Patricia;
Boitard, Christian;
Dubois-Lafforgue, Danièle;
Thébault, Karine

Publication type:

journal article

Growth arrest of PPP2R5C and PPP2R5D double knockout mice indicates a genetic interaction and conserved function for these PP2A B subunits.

Published in:

FASEB Bioadvances, 2022, v. 4, n. 4, p. 273, doi. 10.1096/fba.2021-00130

By:

Dyson, Jade J.;
Abbasi, Fatima;
Varadkar, Prajakta;
McCright, Brent

Publication type:

Article

Human genetic disorders and knockout mice deficient in glycosaminoglycan.

Published in:

2014

By:

Mizumoto, Shuji;
Yamada, Shuhei;
Sugahara, Kazuyuki

Publication type:

Journal Article

NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD.

Published in:

Journal of Psychopharmacology, 2010, v. 24, n. 1, p. 27, doi. 10.1177/0269881108100255

By:

Yan, T. C.;
McQuillin, A.;
Thapar, A.;
Asherson, P.;
Hunt, S. P.;
Stanford, S. C.;
Gurling, H.

Publication type:

Article

Complications associated with genetic background effects in research using knockout mice.

Published in:

Psychopharmacology, 1999, v. 147, n. 1, p. 5, doi. 10.1007/s002130051128

By:

Phillips, Tamara J.;
Hen, Rene;
Crabbe, John C.

Publication type:

Article

Pkd1 and Wnt5a genetically interact to control lymphatic vascular morphogenesis in mice.

Published in:

Developmental Dynamics, 2022, v. 251, n. 2, p. 336, doi. 10.1002/dvdy.390

By:

Chau, Tevin C. Y.;
Baek, Sungmin;
Coxam, Baptiste;
Skoczylas, Renae;
Rondon‐Galeano, Maria;
Bower, Neil I.;
Wainwright, Elanor N.;
Stacker, Steven A.;
Cooper, Helen M.;
Koopman, Peter A.;
Lagendijk, Anne K.;
Harvey, Natasha L.;
François, Mathias;
Hogan, Benjamin M.

Publication type:

Article

Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of pain and anxiety symptoms in Parkinson's disease mice model.

Published in:

Molecular Pain, 2024, p. 1, doi. 10.1177/17448069241266683

By:

Zhou, Zhaoxiang;
Chen, Qi-Yu;
Zhuo, Min;
Xu, Ping-Yi

Publication type:

Article

Cyclic‐di‐GMP induces inflammation and acute lung injury through direct binding to MD2.

Published in:

Clinical & Translational Medicine, 2024, v. 14, n. 8, p. 1, doi. 10.1002/ctm2.1744

By:

Qian, Chenchen;
Zhu, Weiwei;
Wang, Jiong;
Wang, Zhe;
Tang, Weiyang;
Liu, Xin;
Jin, Bo;
Xu, Yong;
Zhang, Yuyang;
Liang, Guang;
Wang, Yi

Publication type:

Article

Upregulation of Acid-Sensing Ion Channel 1a in the Anterior Cingulate Cortex by TNF-α/NF-κB Pathway Contributes to Diabetes-Related Pain.

Published in:

Diabetes, 2025, v. 74, n. 6, p. 1007, doi. 10.2337/db24-0847

By:

Jiang, Ai-Jun;
Wei, Hong-Rui;
Chu, Sijia;
Wang, Mengyuan;
Yan, Jinling;
Song, Xing-Lei;
Xu, Tian-Le;
Zhang, Zhi;
Jin, Yan;
Wang, Wei

Publication type:

Article

Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload.

Published in:

Liver International, 2016, v. 36, n. 2, p. 246, doi. 10.1111/liv.12893

By:

Das, Subhash K.;
DesAulniers, Jessica;
Dyck, Jason R. B.;
Kassiri, Zamaneh;
Oudit, Gavin Y.

Publication type:

Article

Parthanatos initiated by ROS-induced DNA damage is involved in intestinal epithelial injury during necrotizing enterocolitis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02114-z

By:

Xu, Lingqi;
Ma, Shurong;
Qu, Minhan;
Li, Na;
Sun, Xu;
Wang, Tingting;
Chen, Lulu;
Zhu, Jie;
Ding, Yifang;
Gong, Yuan;
Hu, Fangjie;
Dong, Zhenzhen;
Zhang, Rui;
Wang, Jiang Huai;
Wang, Jian;
Zhou, Huiting

Publication type:

Article

Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.87434

By:

Xianwei Chen;
Yanfeng Li;
Jin Xu;
Yong Cui;
Qian Wu;
Haidi Yin;
Yuying Li;
Chuan Gao;
Liwen Jiang;
Huating Wang;
Zilong Wen;
Zhongping Yao;
Zhenguo Wu

Publication type:

Article

Role of alpha-1 antitrypsin in Bruch's membrane integrity.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96570-x

By:

Cheng, Shun-Yun;
Giguere, Delaney;
Silverstein, Ilana;
Conza, Adrienne;
Seddon, Johanna M.;
Kim, San;
Iwata, Takeshi;
Mueller, Christian;
Punzo, Claudio

Publication type:

Article

DNases improve effectiveness of antibiotic treatment in murine polymicrobial sepsis.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1254838

By:

Willemsen, Jan-Fritjof;
Wenskus, Julia;
Lenz, Moritz;
Rhode, Holger;
Trochimiuk, Madgalena;
Appl, Birgit;
Pagarol-Raluy, Laia;
Börnigen, Daniela;
Bang, Corinna;
Reinshagen, Konrad;
Herrmann, Martin;
Elrod, Julia;
Boettcher, Michael

Publication type:

Article

Regional differences in nitrergic innervation of the smooth muscle of murine lower oesophageal sphincter.

Published in:

2008

By:

Zhang, Y.;
Mashimo, H.;
Paterson, W. G.

Publication type:

journal article

High nitrate levels in skeletal muscle contribute to nitric oxide generation via a nitrate/nitrite reductive pathway in mice that lack the nNOS enzyme.

Published in:

Frontiers in Physiology, 2024, p. 01, doi. 10.3389/fphys.2024.1352242

By:

Upanan, Supranee;
Jeeyoung Lee;
Tunau-Spencer, Khalid J.;
Rajvanshi, Praveen K.;
Wright, Elizabeth C.;
Noguchi, Constance T.;
Schechter, Alan N.

Publication type:

Article

Connexin36 Gap Junction Blockade Is Ineffective at Reducing Seizure-Like Event Activity in Neocortical Mouse Slices.

Published in:

Epilepsy Research & Treatment, 2010, p. 1, doi. 10.1155/2010/310753

By:

Voss, Logan J.;
NoortjeMutsaerts;
Sleigh, James W.

Publication type:

Article

Trophoblast glycoprotein is required for efficient synaptic vesicle exocytosis from retinal rod bipolar cells.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 01, doi. 10.3389/fncel.2023.1306006

By:

Wakeham, Colin M.;
Qing Shi;
Gaoying Ren;
Haley, Tammie L.;
Duvoisin, Robert M.;
von Gersdorff, Henrique;
Morgans, Catherine W.

Publication type:

Article

Lack of Vesicular Zinc Does Not Affect the Behavioral Phenotype of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation Mice.

Published in:

Frontiers in Behavioral Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnbeh.2022.769322

By:

Sandoval, Katy Celina;
Thackray, Sarah E.;
Wong, Alison;
Niewinski, Nicole;
Chipak, Colten;
Rehal, Suhkjinder;
Dyck, Richard H.

Publication type:

Article

Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms.

Published in:

Frontiers in Neuroscience, 2020, v. 11, p. N.PAG, doi. 10.3389/fnins.2020.602697

By:

Ren, Xiangpeng;
Chen, Jiang-Fan

Publication type:

Article

Investigating the temporal roles of decorin and biglycan in tendon healing.

Published in:

Journal of Orthopaedic Research, 2023, v. 41, n. 10, p. 2238, doi. 10.1002/jor.25590

By:

Leahy, Thomas P.;
Fung, Ashley K.;
Weiss, Stephanie N.;
Dyment, Nathaniel A.;
Soslowsky, Louis J.

Publication type:

Article

Common Genetic Variation and Haplotypes of the Anion Exchanger SLC4A2 in Primary Biliary Cirrhosis.

Published in:

American Journal of Gastroenterology (Springer Nature), 2009, v. 104, n. 6, p. 1406, doi. 10.1038/ajg.2009.103

By:

Juran, Brian D.;
Atkinson, Elizabeth J.;
Larson, Joseph J.;
Schlicht, Erik M.;
Lazaridis, Konstantinos N.

Publication type:

Article

Brain Aromatase and the Regulation of Sexual Activity in Male Mice.

Published in:

Endocrinology, 2020, v. 161, n. 10, p. 1, doi. 10.1210/endocr/bqaa137

By:

Brooks, David C;
V, John S Coon;
Ercan, Cihangir M;
Xu, Xia;
Dong, Hongxin;
Levine, Jon E;
Bulun, Serdar E;
Zhao, Hong

Publication type:

Article

STING Contributes to Pulmonary Hypertension by Targeting IFN and BMPR2 Signaling through Regulating of F2RL3.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2024, v. 71, n. 3, p. 356, doi. 10.1165/rcmb.2023-0308OC

By:

Deng, Lin;
Cao, Chengrui;
Cai, Zongye;
Wang, Ziping;
Leng, Bin;
Chen, Zhen;
Kong, Fanhao;
Zhou, Zhiyue;
He, Jun;
Nie, Xiaowei;
Bian, Jin-Song

Publication type:

Article

The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.

Published in:

Epilepsia (Series 4), 2012, v. 53, p. 142, doi. 10.1111/j.1528-1167.2012.03485.x

By:

Menegola, Milena;
Clark, Eliana;
Trimmer, James S.

Publication type:

Article

Are developmental dysplastic lesions epileptogenic?

Published in:

Epilepsia (Series 4), 2012, v. 53, p. 35, doi. 10.1111/j.1528-1167.2012.03473.x

By:

Schwartzkroin, Philip A.;
Wenzel, H. Jürgen

Publication type:

Article

A brief history on the oscillating roles of thalamus and cortex in absence seizures.

Published in:

Epilepsia (Series 4), 2012, v. 53, n. 5, p. 779, doi. 10.1111/j.1528-1167.2012.03421.x

By:

Avoli, Massimo

Publication type:

Article

Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1 genes.

Published in:

BMC Biology, 2014, v. 12, n. 1, p. 1, doi. 10.1186/s12915-014-0099-8

By:

Madon-Simon, Marta;
Cowley, Michael;
Garfield, Alastair S.;
Moorwood, Kim;
Bauer, Steven R.;
Ward, Andrew

Publication type:

Article

Overexpression of SMYD3 Promotes Autosomal Dominant Polycystic Kidney Disease by Mediating Cell Proliferation and Genome Instability.

Published in:

Biomedicines, 2024, v. 12, n. 3, p. 603, doi. 10.3390/biomedicines12030603

By:

Agborbesong, Ewud;
Zhou, Julie Xia;
Zhang, Hongbing;
Li, Linda Xiaoyan;
Harris, Peter C.;
Calvet, James P.;
Li, Xiaogang

Publication type:

Article

Loss of the Synuclein Family Members Differentially Affects Baseline- and Apomorphine-Associated EEG Determinants in Single-, Double- and Triple-Knockout Mice.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3128, doi. 10.3390/biomedicines10123128

By:

Vorobyov, Vasily;
Deev, Alexander;
Sukhanova, Iuliia;
Morozova, Olga;
Oganesyan, Zoya;
Chaprov, Kirill;
Buchman, Vladimir L.

Publication type:

Article

Animal Models of Autism Spectrum Disorders and Behavioral Techniques of their Examination.

Published in:

Neurophysiology, 2016, v. 48, n. 5, p. 380, doi. 10.1007/s11062-017-9613-2

By:

Hrabovska, S.;
Salyha, Yu.

Publication type:

Article

Effect of genetic background on acoustic startle response in fragile X knockout mice.

Published in:: Genetics Research, 2008, v. 90, n. 4, p. 341, doi. 10.1017/S0016672308009415
Publication type:: Article