Editorial finding the proverbial needle in the haystack…& then what? Clonally‐Derived cell lines.
- Published in:
- Biotechnology Progress, 2018, v. 34, n. 3, p. 557, doi. 10.1002/btpr.2675
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- Publication type:
- Article
Works matching IS 87567938 AND DT 2018 AND VI 34 AND IP 3
Results: 27
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Effective and efficient characterization of Chinese hamster ovary production cell lines using automated intracellular staining and statistical modeling.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 570, doi. 10.1002/btpr.2667
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- Article
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Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 613, doi. 10.1002/btpr.2666
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- Article
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Antibody expression stability in CHO clonally derived cell lines and their subclones: Role of methylation in phenotypic and epigenetic heterogeneity.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 635, doi. 10.1002/btpr.2655
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- Article
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Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 602, doi. 10.1002/btpr.2646
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- Article
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Monitoring mAb cultivations with in‐situ raman spectroscopy: The influence of spectral selectivity on calibration models and industrial use as reliable PAT tool.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 659, doi. 10.1002/btpr.2635
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- Article
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Development of generic raman models for a GS‐KO<sup>TM</sup> CHO platform process.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 730, doi. 10.1002/btpr.2633
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- Article
8
Selective extraction of lipase and amylase from enzyme mixture by employing liquid emulsion membrane.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 721, doi. 10.1002/btpr.2624
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- Article
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Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementations.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 793, doi. 10.1002/btpr.2623
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- Article
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Development of a novel affinity chromatography resin for platform purification of bispecific antibodies with modified protein a binding avidity.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 650, doi. 10.1002/btpr.2622
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- Article
11
Probing lactate metabolism variations in large‐scale bioreactors.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 756, doi. 10.1002/btpr.2620
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- Article
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One‐pot strategy for on‐site enzyme production, biomass hydrolysis, and ethanol production using the whole solid‐state fermentation medium of mixed filamentous fungi.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 671, doi. 10.1002/btpr.2619
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- Article
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Covalent immobilization of halohydrin dehalogenase for efficient synthesis of epichlorohydrin in an integrated bioreactor.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 784, doi. 10.1002/btpr.2617
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- Article
14
Extraction of bioactive compounds against cardiovascular diseases from Lentinula edodes using a sequential extraction method.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 746, doi. 10.1002/btpr.2616
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- Article
15
Cryopreservation of chicken blastodermal cells and their quality assessment by flow cytometry and transmission electron microscopy.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 778, doi. 10.1002/btpr.2615
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- Article
16
Surfactant selection for a liquid foam‐bed photobioreactor.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 711, doi. 10.1002/btpr.2614
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- Article
17
Effects of ultrasonication variables on the activity and properties of alpha amylase preparation.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 702, doi. 10.1002/btpr.2613
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- Article
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Rapid fabrication of detachable three‐dimensional tissues by layering of cell sheets with heating centrifuge.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 692, doi. 10.1002/btpr.2612
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- Article
19
Investigation of the free heavy chain homodimers of a monoclonal antibody.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 738, doi. 10.1002/btpr.2611
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- Article
20
Physicochemical and catalytic properties of acylase I from aspergillus melleus immobilized on amino‐ and carbonyl‐grafted stöber silica.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 767, doi. 10.1002/btpr.2610
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- Article
21
Analysis of Recombinant Human Serum Albumin Extraction and Degradation in Transgenic Rice Extracts.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 681, doi. 10.1002/btpr.2609
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- Article
22
Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 624, doi. 10.1002/btpr.2594
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- Article
23
Development and characterization of an automated imaging workflow to generate clonally‐derived cell lines for therapeutic proteins.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 584, doi. 10.1002/btpr.2561
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- Article
24
Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally‐derived or not.
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- Biotechnology Progress, 2018, v. 34, n. 3, p. 559, doi. 10.1002/btpr.2560
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25
Issue Information.
- Published in:
- 2018
- Publication type:
- Table of Contents
26
Response to “Statistical analysis of data from limiting dilution cloning to assess monoclonality in generating manufacturing cell lines”.
- Published in:
- 2018
- By:
- Publication type:
- Letter to the Editor
27
Measuring the aggregation of CHO cells prior to single cell cloning allows a more accurate determination of the probability of clonality.
- Published in:
- Biotechnology Progress, 2018, v. 34, n. 3, p. 593, doi. 10.1002/btpr.2500
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- Article