Works matching IS 26628651 AND DT 2022

Results: 50

The pathogenic mechanism of Mycobacterium tuberculosis: implication for new drug development.

Published in:

Molecular Biomedicine, 2022, v. 3, n. 1, p. 1, doi. 10.1186/s43556-022-00106-y

By:

Yan, Weizhu;
Zheng, Yanhui;
Dou, Chao;
Zhang, Guixiang;
Arnaout, Toufic;
Cheng, Wei

Publication type:

Article

Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy.

Published in:

Molecular Biomedicine, 2022, v. 3, n. 1, p. 1, doi. 10.1186/s43556-022-00110-2

By:

Li, Qingfang;
Li, Zhihui;
Luo, Ting;
Shi, Huashan

Publication type:

Article

An overview of PROTACs: a promising drug discovery paradigm.

Published in:

Molecular Biomedicine, 2022, v. 3, n. 1, p. 1, doi. 10.1186/s43556-022-00112-0

By:

Liu, Zi;
Hu, Mingxing;
Yang, Yu;
Du, Chenghao;
Zhou, Haoxuan;
Liu, Chengyali;
Chen, Yuanwei;
Fan, Lei;
Ma, Hongqun;
Gong, Youling;
Xie, Yongmei

Publication type:

Article

TGF-beta signal transduction: biology, function and therapy for diseases.

Published in:

Molecular Biomedicine, 2022, v. 3, n. 1, p. 1, doi. 10.1186/s43556-022-00109-9

By:

Tie, Yan;
Tang, Fan;
Peng, Dandan;
Zhang, Ye;
Shi, Huashan

Publication type:

Article

An overview of PROTACs: a promising drug discovery paradigm.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00112-0

By:

Zi Liu;
Mingxing Hu;
Yu Yang;
Chenghao Du;
Haoxuan Zhou;
Chengyali Liu;
Yuanwei Chen;
Lei Fan;
Hongqun Ma;
Youling Gong;
Yongmei Xie

Publication type:

Article

Inhibition of glycogen synthase kinase-3-beta (GSK3ß) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00111-1

By:

Shapira, Tirosh;
Vimalanathan, Selvarani;
Rens, Celine;
Pichler, Virginia;
Peña-Díaz, Sandra;
Jordana, Grace;
Rees, William;
Winkler, Dirk F. H.;
Sarai, Iqbal;
Steiner, Theodore;
Jean, François;
Pelech, Steven;
Av-Gay, Yossef

Publication type:

Article

Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00110-2

By:

Qingfang Li;
Zhihui Li;
Ting Luo;
Huashan Shi

Publication type:

Article

TGF-beta signal transduction: biology, function and therapy for diseases.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00109-9

By:

Yan Tie;
Fan Tang;
Dandan Peng;
Ye Zhang;
Huashan Shi

Publication type:

Article

Metformin in therapeutic applications in human diseases: its mechanism of action and clinical study.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00108-w

By:

Yang Du;
Ya-Juan Zhu;
Yi-Xin Zhou;
Jing Ding;
Ji-Yan Liu

Publication type:

Article

Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00107-x

By:

Zixi Wang;
Yurou Xing;
Bingjie Li;
Xiaoyu Li;
Bin Liu;
Yongsheng Wang

Publication type:

Article

The pathogenic mechanism of Mycobacterium tuberculosis: implication for new drug development.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00106-y

By:

Weizhu Yan;
Yanhui Zheng;
Chao Dou;
Guixiang Zhang;
Arnaout, Toufic;
Wei Cheng

Publication type:

Article

The anti-ferroptotic role of FSP1: current molecular mechanism and therapeutic approach.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00105-z

By:

Furong Zeng;
Xiang Chen;
Guangtong Deng

Publication type:

Article

Distribution and characterization of extrachromosomal circular DNA in colorectal cancer.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00104-0

By:

Zhehang Chen;
Yadong Qi;
Jiamin He;
Chaochao Xu;
Qiwei Ge;
Wei Zhuo;
Jianmin Si;
Shujie Chen

Publication type:

Article

Alterations of the fecal microbiota in relation to acute COVID-19 infection and recovery.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00103-1

By:

Yue Sandra Yin;
Minacapelli, Carlos D.;
Parmar, Veenat;
Catalano, Carolyn C.;
Bhurwal, Abhishek;
Gupta, Kapil;
Rustgi, Vinod K.;
Blaser, Martin J.

Publication type:

Article

Development of therapeutic antibodies for the treatment of diseases.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00100-4

By:

Zeng Wang;
Guoqing Wang;
Huaqing Lu;
Hongjian Li;
Mei Tang;
Aiping Tong

Publication type:

Article

The role of Hedgehog and Notch signaling pathway in cancer.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00099-8

By:

Ruolan Xia;
Maosen Xu;
Jing Yang;
Xuelei Ma

Publication type:

Article

Development of therapeutic vaccines for the treatment of diseases.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00098-9

By:

Yaomei Tian;
Die Hu;
Yuhua Li;
Li Yang

Publication type:

Article

ZBP1 contributes to interferonopathies caused by impaired ADAR1 function.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00097-w

By:

Xiuwu Fang;
Long Zhang

Publication type:

Article

Predictive value of serum irisin for chronic heart failure in patients with type 2 diabetes mellitus.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00096-x

By:

Berezin, Alexander A.;
Fushtey, Ivan M.;
Pavlov, Sergii V.;
Berezin, Alexander E.

Publication type:

Article

CRISPR/Cas systems usher in a new era of disease treatment and diagnosis.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00095-y

By:

Ruiting Li;
Qin Wang;
Kaiqin She;
Fang Lu;
Yang Yang

Publication type:

Article

PI3K-PANK4: a new target for de novo synthesis of coenzyme A.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00094-z

By:

Jizhong Guan;
Long Zhang;
Fangfang Zhou

Publication type:

Article

Identification of a Sialosides binding pocket in early-lineage SARS-CoV-2 via an optimized STD NMR method: a novel explanation for coronavirus virulence and zoonosis.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00093-0

By:

Geng Chen;
Wei Gao;
Yang Du

Publication type:

Article

The vertebrate- and testis-specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00092-1

By:

Hongying Hao;
Baolu Shi;
Jiacheng Zhang;
Ao Dai;
Wenhao Li;
Haidi Chen;
Wenya Ji;
Chenjia Gong;
Chang Zhang;
Jing Li;
Li Chen;
Bin Yao;
Peng Hu;
Hao Yang;
Brosius, Juergen;
Shanshan Lai;
Qinghua Shi;
Cheng Deng

Publication type:

Article

C(- 106)T polymorphism in ALR2 and risk of microvascular complications in T2DM patients in north Indian population.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00087-y

By:

Mishra, Archana;
Ahmad, Mohammad Kaleem;
Ahsan, Haseeb;
Khan, Saba;
Mehrotra, Sudhir;
Alam, Roshan

Publication type:

Article

Cleavage of the selective autophagy receptor SQSTM1/p62 by the SARS-CoV-2 main protease NSP5 prevents the autophagic degradation of viral membrane proteins.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00083-2

By:

Yabin Zhang;
Shiyan Liu;
Qingjia Xu;
Huihui Li;
Kefeng Lu

Publication type:

Article

The role of the gut microbiota in health and cardiovascular diseases.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00091-2

By:

Lu Wang;
Shiqi Wang;
Qing Zhang;
Chengqi He;
Chenying Fu;
Quan Wei

Publication type:

Article

Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00090-3

By:

Lele Cui;
Hao Li;
Yufeng Xi;
Qianli Hu;
Huimin Liu;
Jiaqi Fan;
Yijuan Xiang;
Xing Zhang;
Weiwei Shui;
Ying Lai

Publication type:

Article

A new strategy: identification of specific antibodies for neutralizing epitope on SARS-CoV-2 S protein by LC-MS/MS combined with immune repertoire.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00085-0

By:

Meng Yu;
Zhu Zhu;
Yanqun Wang;
Pingzhang Wang;
Xiaodong Jia;
Jie Wang;
Lei Liu;
Wanbing Liu;
Yaqiong Zheng;
Guomei Kou;
Weiyan Xu;
Jing Huang;
Fengmin Lu;
Xiajuan Zou;
Shangen Zheng;
Yinying Lu;
Jincun Zhao;
Hui Dai;
Xiaoyan Qiu

Publication type:

Article

MicroRNA-379-5p regulates free cholesterol accumulation and relieves diet induced-liver damage in db/db mice via STAT1/HMGCS1 axis.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00089-w

By:

Yunxia Dong;
Chuwei Yu;
Ningning Ma;
Xiaoding Xu;
Qian Wu;
Henglei Lu;
Likun Gong;
Jing Chen;
Jin Ren

Publication type:

Article

Natural polyphenol self-assembled pH-responsive nanoparticles loaded into reversible hydrogel to inhibit oral bacterial activity.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00082-3

By:

Yunyun Qi;
Jinxiang Yang;
Yaping Chi;
Peng Wen;
Zhongying Wang;
Shiyi Yu;
Rui Xue;
Jingmin Fan;
Hong Li;
Wen Chen;
Xinjun Wang;
Yan Zhang;
Gang Guo;
Bo Han

Publication type:

Article

Combinatorial therapeutic approaches of photodynamic therapy and immune checkpoint blockade for colon cancer treatment.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00086-z

By:

Yang Hao;
Chih Kit Chung;
Zili Gu;
Timo Schomann;
Xiaoxu Dong;
in 't Veld, Ruben V. Huis;
Camps, Marcel G. M.;
Dijke, Peter ten;
Ossendorp, Ferry A.;
Cruz, Luis J.

Publication type:

Article

Mesenchymal stem cells-based therapy in liver diseases.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00088-x

By:

Heng-Tong Han;
Wei-Lin Jin;
Xun Li

Publication type:

Article

The inhibition of protein translation promotes tumor angiogenic switch.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00081-4

By:

Hui Luo;
Yuge Shen;
Weiting Liao;
Qiqi Li;
Ni Wu;
Jian Zhong;
Chaoxin Xiao;
Jia Gan;
Yun Yang;
Dong, E.;
Guimin Zhang;
Binrui Liu;
Xiaozhu Yue;
Lin Xu;
Yan Liu;
Chengjian Zhao;
Qian Zhong;
Hanshuo Yang

Publication type:

Article

Identifying drivers of breast cancer metastasis in progressively invasive subpopulations of zebrafish-xenografted MDA-MB-231.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00080-5

By:

Jerry Xiao;
McGill, Joseph R.;
Nasir, Apsra;
Lekan, Alexander;
Johnson, Bailey;
Wilkins, Devan J.;
Pearson, Gray W.;
Tanner, Kandice;
Goodarzi, Hani;
Glasgow, Eric;
Schlegel, Richard;
Agarwal, Seema

Publication type:

Article

Transglutaminase-2 mediates acquisition of neratinib resistance in metastatic breast cancer.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00079-y

By:

Shinde, Aparna;
Cotul, Eylem Kulkoyluoglu;
Hao Chen;
Smith, Andrew;
Libring, Sarah;
Solorio, Luis;
Wendt, Michael K.

Publication type:

Article

Human Identical Sequences, hyaluronan, and hymecromone - the new mechanism and management of COVID-19.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00077-0

By:

Shuai Yang;
Ying Tong;
Lu Chen;
Wenqiang Yu

Publication type:

Article

Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00076-1

By:

Peibin Liang;
Yanpeng Li;
Rui Xu;
Nandakumar, Kutty Selva;
Stawikowska, Roma;
Fields, Gregg B.;
Holmdahl, Rikard

Publication type:

Article

Post-translational modifications in liquid-liquid phase separation: a comprehensive review.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00075-2

By:

Jingxian Li;
Mengdi Zhang;
Weirui Ma;
Bing Yang;
Huasong Lu;
Fangfang Zhou;
Long Zhang

Publication type:

Article

Omicron-included mutation-induced changes in epitopes of SARS-CoV-2 spike protein and effectiveness assessments of current antibodies.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00074-3

By:

Du Guo;
Huaichuan Duan;
Yan Cheng;
Yueteng Wang;
Jianping Hu;
Hubing Shi

Publication type:

Article

Histamine and histamine receptor H1 (HRH1) axis: new target for enhancing immunotherapy response.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00073-4

By:

Ziyi Bai;
Jiayuan Ai;
Xiawei Wei

Publication type:

Article

Enhancing prime editing via inhibition of mismatch repair pathway.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00072-5

By:

Lurong Jiang;
Shaohua Yao

Publication type:

Article

Therapeutic progress and challenges for triple negative breast cancer: targeted therapy and immunotherapy.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00071-6

By:

Ruoning Yang;
Yueyi Li;
Hang Wang;
Taolin Qin;
Xiaomeng Yin;
Xuelei Ma

Publication type:

Article

Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00070-7

By:

Hang Ruan;
Leibowitz, Brian J.;
Yingpeng Peng;
Lin Shen;
Lujia Chen;
Kuang, Charlie;
Schoen, Robert E.;
Xinghua Lu;
Lin Zhang;
Jian Yu

Publication type:

Article

Identification of a gene signature for the prediction of recurrence and progression in non-muscle-invasive bladder cancer.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00069-0

By:

Dalla, Emiliano;
Picco, Raffaella;
Novara, Giacomo;
Dal Moro, Fabrizio;
Brancolini, Claudio

Publication type:

Article

Structure-activity features of purines and their receptors: implications in cell physiopathology.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-022-00068-1

By:

Díaz-Muñoz, Mauricio;
Hernández-Muñoz, Rolando;
Butanda-Ochoa, Armando

Publication type:

Article

Stem cell therapy for COVID-19 pneumonia.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-021-00067-8

By:

Kebria, Maziar Malekzadeh;
Milan, Peiman Brouki;
Peyravian, Noshad;
Kiani, Jafar;
Khatibi, Soheil;
Mozafari, Masoud

Publication type:

Article

Combinatorial inhibition of BTK, PI3K-AKT and BRD4-MYC as a strategy for treatment of mantle cell lymphoma.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-021-00066-9

By:

Vann, Kendra R.;
Pal, Dhananjaya;
Smith, Audrey L.;
Sahar, Namood-e;
Krishnaiah, Maddeboina;
El-Gamal, Dalia;
Kutateladze, Tatiana G.

Publication type:

Article

Long noncoding RNA RP11-241J12.3 targeting pyruvate carboxylase promotes hepatocellular carcinoma aggressiveness by disrupting pyruvate metabolism and the DNA mismatch repair system.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-021-00065-w

By:

Liuliu Cheng;
Shichuan Hu;
Jinhu Ma;
Yongheng Shu;
Yanwei Chen;
Bin Zhang;
Zhongbing Qi;
Yunmeng Wang;
Yan Zhang;
Yuwei Zhang;
Ping Cheng

Publication type:

Article

Autoantibodies against cytoskeletons and lysosomal trafficking discriminate sarcoidosis from healthy controls, tuberculosis and lung cancers.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-021-00064-x

By:

Hanoudi, Samer Najeeb;
Talwar, Harvinder;
Draghici, Sorin;
Samavati, Lobelia

Publication type:

Article

Optimization of miR-22 expression cassette for rAAV delivery on diabetes.

Published in:

Molecular Biomedicine, 2022, p. 1, doi. 10.1186/s43556-021-00063-y

By:

Li Yang;
Wenya Du;
Zhaoyue Zheng;
Li Wang;
Lin Xiao;
Qingzhe Yang;
Qiukui Hao;
Jiao Zhou;
Jintao Du;
Jun Li;
Valencia, C. Alexander;
Birong Dong;
Hoi Yee Chow;
Xianghui Fu;
Biao Dong

Publication type:

Article