Works matching IS 2397768X AND DT 2021 AND VI 5 AND IP 1

Results: 104

Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00238-4

By:

Williamson, Laura M.;
Rive, Craig M.;
Di Francesco, Daniela;
Titmuss, Emma;
Chun, Hye-Jung E.;
Brown, Scott D.;
Milne, Katy;
Pleasance, Erin;
Lee, Anna F.;
Yip, Stephen;
Rosenbaum, Daniel G.;
Hasselblatt, Martin;
Johann, Pascal D.;
Kool, Marcel;
Harvey, Melissa;
Dix, David;
Renouf, Daniel J.;
Holt, Robert A.;
Nelson, Brad H.;
Hirst, Martin

Publication type:

Article

Pharmacogenomics characterization of the MDM2 inhibitor MI-773 reveals candidate tumours and predictive biomarkers.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00235-7

By:

Vuaroqueaux, Vincent;
Hendriks, Hans R.;
Al-Hasani, Hoor;
Peille, Anne-Lise;
Das, Samayita;
Fiebig, Heinz-Herbert

Publication type:

Article

Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00239-3

By:

Angeles, Arlou Kristina;
Christopoulos, Petros;
Yuan, Zhao;
Bauer, Simone;
Janke, Florian;
Ogrodnik, Simon John;
Reck, Martin;
Schlesner, Matthias;
Meister, Michael;
Schneider, Marc A.;
Dietz, Steffen;
Stenzinger, Albrecht;
Thomas, Michael;
Sültmann, Holger

Publication type:

Article

High TGF-β signature predicts immunotherapy resistance in gynecologic cancer patients treated with immune checkpoint inhibition.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00242-8

By:

Ni, Ying;
Soliman, Ahmed;
Joehlin-Price, Amy;
Rose, Peter G.;
Vlad, Anda;
Edwards, Robert P.;
Mahdi, Haider

Publication type:

Article

Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00240-w

By:

Coleman, Niamh;
Subbiah, Vivek;
Pant, Shubham;
Patel, Keyur;
Roy-Chowdhuri, Sinchita;
Yedururi, Sireesha;
Johnson, Amber;
Yap, Timothy A.;
Rodon, Jordi;
Shaw, Kenna;
Meric-Bernstam, Funda

Publication type:

Article

Selective KRAS G12C inhibitors in non-small cell lung cancer: chemistry, concurrent pathway alterations, and clinical outcomes.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00237-5

By:

Palma, Gabriela;
Khurshid, Faisal;
Lu, Kevin;
Woodward, Brian;
Husain, Hatim

Publication type:

Article

FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00236-6

By:

Gultekin, Okan;
Gonzalez-Molina, Jordi;
Hardell, Elin;
Moyano-Galceran, Lidia;
Mitsios, Nicholas;
Mulder, Jan;
Kokaraki, Georgia;
Isaksson, Anders;
Sarhan, Dhifaf;
Lehti, Kaisa;
Carlson, Joseph W.

Publication type:

Article

Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00241-9

By:

Schaufler, Diana;
Ast, David F.;
Tumbrink, Hannah L.;
Abedpour, Nima;
Maas, Lukas;
Schwäbe, Ayla E.;
Spille, Inga;
Lennartz, Stefanie;
Fassunke, Jana;
Aldea, Mihaela;
Besse, Benjamin;
Planchard, David;
Nogova, Lucia;
Michels, Sebastian;
Kobe, Carsten;
Persigehl, Thorsten;
Westphal, Theresa;
Koleczko, Sophia;
Fischer, Rieke;
Weber, Jan-Phillip

Publication type:

Article

An analysis of research biopsy core variability from over 5000 prospectively collected core samples.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00234-8

By:

Bhamidipati, Deepak;
Verma, Anuj;
Sui, Dawen;
Maru, Dipen;
Mathew, Grace;
Lang, Wenhua;
Posadas, Juan;
Hein, Joshua;
Kopetz, Scott;
Futreal, Andrew;
Wistuba, Ignacio I.;
Gupta, Sanjay;
Lee, J. Jack;
Overman, Michael J.;
Tam, Alda L.

Publication type:

Article

GD2 CAR T cells against human glioblastoma.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00233-9

By:

Prapa, Malvina;
Chiavelli, Chiara;
Golinelli, Giulia;
Grisendi, Giulia;
Bestagno, Marco;
Di Tinco, Rosanna;
Dall'Ora, Massimiliano;
Neri, Giovanni;
Candini, Olivia;
Spano, Carlotta;
Petrachi, Tiziana;
Bertoni, Laura;
Carnevale, Gianluca;
Pugliese, Giuseppe;
Depenni, Roberta;
Feletti, Alberto;
Iaccarino, Corrado;
Pavesi, Giacomo;
Dominici, Massimo

Publication type:

Article

Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00230-y

By:

Puccini, Alberto;
Seeber, Andreas;
Xiu, Joanne;
Goldberg, Richard M.;
Soldato, Davide;
Grothey, Axel;
Shields, Anthony F.;
Salem, Mohamed E.;
Battaglin, Francesca;
Berger, Martin D.;
El-Deiry, Wafik S.;
Tokunaga, Ryuma;
Naseem, Madiha;
Zhang, Wu;
Arora, Sukeshi Patel;
Khushman, Moh'd M.;
Hall, Michael J.;
Philip, Philip A.;
Marshall, John L.;
Korn, W. Michael

Publication type:

Article

Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00232-w

By:

Labrie, Marilyne;
Li, Allen;
Creason, Allison;
Betts, Courtney;
Keck, Jamie;
Johnson, Brett;
Sivagnanam, Shamilene;
Boniface, Christopher;
Ma, Hongli;
Blucher, Aurora;
Chang, Young Hwan;
Chin, Koei;
Vuky, Jacqueline;
Guimaraes, Alexander R.;
Downey, Molly;
Lim, Jeong Youn;
Gao, Lina;
Siex, Kiara;
Parmar, Swapnil;
Kolodzie, Annette

Publication type:

Article

Evolution of MET and NRAS gene amplification as acquired resistance mechanisms in EGFR mutant NSCLC.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00231-x

By:

Peters, T. L.;
Patil, T.;
Le, A. T.;
Davies, K. D.;
Brzeskiewicz, P. M.;
Nijmeh, H.;
Bao, L.;
Camidge, D. R.;
Aisner, D. L.;
Doebele, R. C.

Publication type:

Article

Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00228-6

By:

Li, Yingmei;
Polyak, Dina;
Lamsam, Layton;
Connolly, Ian David;
Johnson, Eli;
Khoeur, Lina Khav;
Andersen, Stephanie;
Granucci, Monica;
Stanley, Geoff;
Liu, Boxiang;
Nagpal, Seema;
Hayden Gephart, Melanie

Publication type:

Article

BAP1 methylation: a prognostic marker of uveal melanoma metastasis.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00226-8

By:

Bakhoum, Mathieu F.;
Curtis, Ellis J.;
Goldbaum, Michael H.;
Mischel, Paul S.

Publication type:

Article

How I faced my prostate cancer: a molecular biologist's perspective.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00229-5

By:

Zuradelli, Monica;
Lazzeri, Massimo;
Lopci, Egesta;
Zucali, Paolo Andrea;
Balzarini, Luca;
Guazzoni, Giorgio;
Colombo, Piergiuseppe;
Scorsetti, Marta;
Franzese, Ciro;
Asselta, Rosanna;
Soldà, Giulia;
Duga, Stefano

Publication type:

Article

Genetic mutation and biological pathway prediction based on whole slide images in breast carcinoma using deep learning.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00225-9

By:

Qu, Hui;
Zhou, Mu;
Yan, Zhennan;
Wang, He;
Rustgi, Vinod K.;
Zhang, Shaoting;
Gevaert, Olivier;
Metaxas, Dimitris N.

Publication type:

Article

Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00224-w

By:

Koh, Siang-Boon;
Dontchos, Brian N.;
Bossuyt, Veerle;
Edmonds, Christine;
Cristea, Simona;
Melkonjan, Nsan;
Mortensen, Lindsey;
Ma, Annie;
Beyerlin, Kassidy;
Denault, Elyssa;
Niehoff, Elizabeth;
Hirz, Taghreed;
Sykes, David B.;
Michor, Franziska;
Specht, Michelle;
Lehman, Constance;
Ellisen, Leif W.;
Spring, Laura M.

Publication type:

Article

Author Correction: Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population.

Published in:

2021

By:

Westphalen, C. B.;
Krebs, M. G.;
Le Tourneau, C.;
Sokol, E. S.;
Maund, S. L.;
Wilson, T. R.;
Jin, D. X.;
Newberg, J. Y.;
Fabrizio, D.;
Veronese, L.;
Thomas, M.;
de Braud, F.

Publication type:

Correction Notice

Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00219-7

By:

Ahuno, Samuel Terkper;
Doebley, Anna-Lisa;
Ahearn, Thomas U.;
Yarney, Joel;
Titiloye, Nicholas;
Hamel, Nancy;
Adjei, Ernest;
Clegg-Lamptey, Joe-Nat;
Edusei, Lawrence;
Awuah, Baffour;
Song, Xiaoyu;
Vanderpuye, Verna;
Abubakar, Mustapha;
Duggan, Maire;
Stover, Daniel G.;
Nyarko, Kofi;
Bartlett, John M. S.;
Aitpillah, Francis;
Ansong, Daniel;
Gardner, Kevin L.

Publication type:

Article

Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00206-y

By:

Westphalen, C. B.;
Krebs, M. G.;
Le Tourneau, C.;
Sokol, E. S.;
Maund, S. L.;
Wilson, T. R.;
Jin, D. X.;
Newberg, J. Y.;
Fabrizio, D.;
Veronese, L.;
Thomas, M.;
de Braud, F.

Publication type:

Article

Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.

Published in:

2021

By:

Conteduca, Vincenza;
Ku, Sheng-Yu;
Fernandez, Luisa;
Dago-Rodriquez, Angel;
Lee, Jerry;
Jendrisak, Adam;
Slade, Megan;
Gilbertson, Cole;
Manohar, Jyothi;
Sigouros, Michael;
Wang, Yipeng;
Dittamore, Ryan;
Wenstrup, Rick;
Mosquera, Juan Miguel;
Schonhoft, Joseph D.;
Beltran, Himisha

Publication type:

Correction Notice

Real-world data analyses unveiled the immune-related adverse effects of immune checkpoint inhibitors across cancer types.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00223-x

By:

Wang, Feicheng;
Yang, Shihao;
Palmer, Nathan;
Fox, Kathe;
Kohane, Isaac S.;
Liao, Katherine P.;
Yu, Kun-Hsing;
Kou, S. C.

Publication type:

Article

Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00221-z

By:

Li, Binghao;
Qu, Hao;
Zhang, Jing;
Pan, Weibo;
Liu, Meng;
Yan, Xiaobo;
Huang, Xin;
He, Xuexin;
Lin, Dong;
Liu, Sisi;
Guan, Ruting;
Wu, Yong;
Ou, Qiuxiang;
Bao, Hua;
Xu, Youbin;
Wu, Xue;
Shao, Yang;
Lin, Nong

Publication type:

Article

Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00220-0

By:

Bitzer, Michael;
Spahn, Stephan;
Babaei, Sepideh;
Horger, Marius;
Singer, Stephan;
Schulze-Osthoff, Klaus;
Missios, Pavlos;
Gatidis, Sergios;
Nann, Dominik;
Mattern, Sven;
Scheble, Veit;
Nikolaou, Konstantin;
Armeanu-Ebinger, Sorin;
Schulze, Martin;
Schroeder, Christopher;
Biskup, Saskia;
Beha, Janina;
Claassen, Manfred;
Ruhm, Kristina;
Poso, Antti

Publication type:

Article

Artificial intelligence for the next generation of precision oncology.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00216-w

By:

Ballester, Pedro J.;
Carmona, Javier

Publication type:

Article

Clinical, genetic and pharmacological data support targeting the MEK5/ERK5 module in lung cancer.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00218-8

By:

Sánchez-Fdez, Adrián;
Re-Louhau, María Florencia;
Rodríguez-Núñez, Pablo;
Ludeña, Dolores;
Matilla-Almazán, Sofía;
Pandiella, Atanasio;
Esparís-Ogando, Azucena

Publication type:

Article

Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00211-1

By:

Conteduca, Vincenza;
Ku, Sheng-Yu;
Fernandez, Luisa;
Dago-Rodriquez, Angel;
Lee, Jerry;
Jendrisak, Adam;
Slade, Megan;
Gilbertson, Cole;
Manohar, Jyothi;
Sigouros, Michael;
Wang, Yipeng;
Dittamore, Ryan;
Wenstrup, Rick;
Mosquera, Juan Miguel;
Schonhoft, Joseph D.;
Beltran, Himisha

Publication type:

Article

Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00215-x

By:

Downes, Charlotte E. J.;
McClure, Barbara J.;
Bruning, John B.;
Page, Elyse;
Breen, James;
Rehn, Jacqueline;
Yeung, David T.;
White, Deborah L.

Publication type:

Article

Retraction Note: Birinapant sensitizes platinum-resistant carcinomas with high levels of cIAP to carboplatin therapy.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00217-9

By:

La, V.;
Fujikawa, R.;
Janzen, D. M.;
Nunez, M.;
Bainvoll, L.;
Hwang, L.;
Faull, K.;
Lawson, G.;
Memarzadeh, S.

Publication type:

Article

A phase I/II study of rovalpituzumab tesirine in delta-like 3—expressing advanced solid tumors.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00214-y

By:

Mansfield, Aaron S.;
Hong, David S.;
Hann, Christine L.;
Farago, Anna F.;
Beltran, Himisha;
Waqar, Saiama N.;
Hendifar, Andrew E.;
Anthony, Lowell B.;
Taylor, Matthew H.;
Bryce, Alan H.;
Tagawa, Scott T.;
Lewis, Karl;
Niu, Jiaxin;
Chung, Christine H.;
Cleary, James M.;
Rossi, Michael;
Ludwig, Carrianne;
Valenzuela, Ricardo;
Luo, Yan;
Aggarwal, Rahul

Publication type:

Article

Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00212-0

By:

Wong, Elyssa Y.;
Xu, Liya;
Shen, Lishuang;
Kim, Mary E.;
Polski, Ashley;
Prabakar, Rishvanth K.;
Shah, Rachana;
Jubran, Rima;
Kim, Jonathan W.;
Biegel, Jaclyn A.;
Gai, Xiaowu;
Kuhn, Peter;
Hicks, James;
Berry, Jesse L.

Publication type:

Article

Quantitative MRI-based radiomics for noninvasively predicting molecular subtypes and survival in glioma patients.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00205-z

By:

Yan, Jing;
Zhang, Bin;
Zhang, Shuaitong;
Cheng, Jingliang;
Liu, Xianzhi;
Wang, Weiwei;
Dong, Yuhao;
Zhang, Lu;
Mo, Xiaokai;
Chen, Qiuying;
Fang, Jin;
Wang, Fei;
Tian, Jie;
Zhang, Shuixing;
Zhang, Zhenyu

Publication type:

Article

Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00209-9

By:

White, Brian S.;
Khan, Suleiman A.;
Mason, Mike J.;
Ammad-ud-din, Muhammad;
Potdar, Swapnil;
Malani, Disha;
Kuusanmäki, Heikki;
Druker, Brian J.;
Heckman, Caroline;
Kallioniemi, Olli;
Kurtz, Stephen E.;
Porkka, Kimmo;
Tognon, Cristina E.;
Tyner, Jeffrey W.;
Aittokallio, Tero;
Wennerberg, Krister;
Guinney, Justin

Publication type:

Article

Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00210-2

By:

Caso, Raul;
Connolly, James G.;
Zhou, Jian;
Tan, Kay See;
Choi, James J.;
Jones, Gregory D.;
Mastrogiacomo, Brooke;
Sanchez-Vega, Francisco;
Nguyen, Bastien;
Rocco, Gaetano;
Molena, Daniela;
Sihag, Smita;
Adusumilli, Prasad S.;
Bott, Matthew J.;
Jones, David R.

Publication type:

Article

Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00206-y

By:

Westphalen, C. B.;
Krebs, M. G.;
Le Tourneau, C.;
Sokol, E. S.;
Maund, S. L.;
Wilson, T. R.;
Jin, D. X.;
Newberg, J. Y.;
Fabrizio, D.;
Veronese, L.;
Thomas, M.;
de Braud, F.

Publication type:

Article

PERK mediates resistance to BRAF inhibition in melanoma with impaired PTEN.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00207-x

By:

Qin, Yifei;
Zuo, Qiang;
Huang, Lei;
Huang, Liping;
Merlino, Glenn;
Yu, Yanlin

Publication type:

Article

Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00204-0

By:

Nakamura, Ikuko Takeda;
Kohsaka, Shinji;
Ikegami, Masachika;
Ikeuchi, Hiroshi;
Ueno, Toshihide;
Li, Kunhua;
Beyett, Tyler S.;
Koyama, Takafumi;
Shimizu, Toshio;
Yamamoto, Noboru;
Takahashi, Fumiyuki;
Takahashi, Kazuhisa;
Eck, Michael J.;
Mano, Hiroyuki

Publication type:

Article

Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00203-1

By:

Oulhen, Marianne;
Pawlikowska, Patrycja;
Tayoun, Tala;
Garonzi, Marianna;
Buson, Genny;
Forcato, Claudio;
Manaresi, Nicolò;
Aberlenc, Agathe;
Mezquita, Laura;
Lecluse, Yann;
Lavaud, Pernelle;
Naltet, Charles;
Planchard, David;
Besse, Benjamin;
Farace, Françoise

Publication type:

Article

Combined FGFR and Akt pathway inhibition abrogates growth of FGFR1 overexpressing EGFR-TKI-resistant NSCLC cells.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00208-w

By:

Terp, Mikkel G.;
Jacobsen, Kirstine;
Molina, Miguel Angel;
Karachaliou, Niki;
Beck, Hans C.;
Bertran-Alamillo, Jordi;
Giménez-Capitán, Ana;
Cardona, Andrés F.;
Rosell, Rafael;
Ditzel, Henrik J.

Publication type:

Article

TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00178-z

By:

Meijer, A. J. M.;
Diepstraten, F. A.;
Langer, T.;
Broer, L.;
Domingo, I. K.;
Clemens, E.;
Uitterlinden, A. G.;
de Vries, A. C. H.;
van Grotel, M.;
Vermeij, W. P.;
Ozinga, R. A.;
Binder, H.;
Byrne, J.;
van Dulmen-den Broeder, E.;
Garrè, M. L.;
Grabow, D.;
Kaatsch, P.;
Kaiser, M.;
Kenborg, L.;
Winther, J. F.

Publication type:

Article

Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00202-2

By:

Finkle, Justin D.;
Boulos, Hala;
Driessen, Terri M.;
Lo, Christine;
Blidner, Richard A.;
Hafez, Ashraf;
Khan, Aly A.;
Lozac'hmeur, Ariane;
McKinnon, Kelly E.;
Perera, Jason;
Zhu, Wei;
Dowlati, Afshin;
White, Kevin P.;
Tell, Robert;
Beaubier, Nike

Publication type:

Article

Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00197-w

By:

Boucher, Yves;
Kumar, Ashwin S.;
Posada, Jessica M.;
Gjini, Evisa;
Pfaff, Kathleen;
Lipschitz, Mikel;
Lako, Ana;
Duda, Dan G.;
Rodig, Scott J.;
Hodi, F. Stephen;
Jain, Rakesh K.

Publication type:

Article

Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00192-1

By:

Goulart, Michelle R.;
Watt, Jennifer;
Siddiqui, Imran;
Lawlor, Rita T.;
Imrali, Ahmet;
Hughes, Christine;
Saad, Amina;
ChinAleong, Joanne;
Hurt, Chris;
Cox, Catrin;
Salvia, Roberto;
Mantovani, Alberto;
Crnogorac-Jurcevic, Tatjana;
Mukherjee, Somnath;
Scarpa, Aldo;
Allavena, Paola;
Kocher, Hemant M.

Publication type:

Article

Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00185-0

By:

Wall, Matthew A.;
Turkarslan, Serdar;
Wu, Wei-Ju;
Danziger, Samuel A.;
Reiss, David J.;
Mason, Mike J.;
Dervan, Andrew P.;
Trotter, Matthew W. B.;
Bassett, Douglas;
Hershberg, Robert M.;
Lomana, Adrián López García de;
Ratushny, Alexander V.;
Baliga, Nitin S.

Publication type:

Article

Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00194-z

By:

Lin, Frank P.;
Thavaneswaran, Subotheni;
Grady, John P.;
Ballinger, Mandy;
Kansara, Maya;
Oakes, Samantha R.;
Desai, Jayesh;
Lee, Chee Khoon;
Simes, John;
Thomas, David M.

Publication type:

Article

A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00191-2

By:

Petak, Istvan;
Kamal, Maud;
Dirner, Anna;
Bieche, Ivan;
Doczi, Robert;
Mariani, Odette;
Filotas, Peter;
Salomon, Anne;
Vodicska, Barbara;
Servois, Vincent;
Varkondi, Edit;
Gentien, David;
Tihanyi, Dora;
Tresca, Patricia;
Lakatos, Dora;
Servant, Nicolas;
Deri, Julia;
du Rusquec, Pauline;
Hegedus, Csilla;
Bello Roufai, Diana

Publication type:

Article

Comprehensive molecular profiling of pulmonary pleomorphic carcinoma.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00201-3

By:

Nagano, Masaaki;
Kohsaka, Shinji;
Hayashi, Takuo;
Ueno, Toshihide;
Kojima, Shinya;
Shinozaki-Ushiku, Aya;
Morita, Shigeki;
Tsuda, Masumi;
Tanaka, Shinya;
Shinohara, Toshiya;
Omori, Yuko;
Sugaya, Fumiko;
Kato, Hiroaki;
Narita, Yoshiaki;
Nakajima, Jun;
Suzuki, Kenji;
Takamochi, Kazuya;
Mano, Hiroyuki

Publication type:

Article

The pan-cancer landscape of crosstalk between epithelial-mesenchymal transition and immune evasion relevant to prognosis and immunotherapy response.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00200-4

By:

Wang, Guangyu;
Xu, Dandan;
Zhang, Zicheng;
Li, Xinhui;
Shi, Jiaqi;
Sun, Jie;
Liu, Huan-Zhong;
Li, Xiaobo;
Zhou, Meng;
Zheng, Tongsen

Publication type:

Article

A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00199-8

By:

Diossy, Miklos;
Sztupinszki, Zsofia;
Borcsok, Judit;
Krzystanek, Marcin;
Tisza, Viktoria;
Spisak, Sandor;
Rusz, Orsolya;
Timar, Jozsef;
Csabai, István;
Fillinger, Janos;
Moldvay, Judit;
Pedersen, Anders Gorm;
Szuts, David;
Szallasi, Zoltan

Publication type:

Article