Works matching IS 23649534 AND DT 2022 AND VI 8 AND IP 1

Results: 22

Glycopeptide antibiotic drug stability in aqueous solution.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00067-0

By:

Jakaria, Sardar M.;
Budil, David E.;
Murtagh, James

Publication type:

Article

Meeting report: Advancing accelerated regulatory review with Real-Time Oncology Review (RTOR), Project Orbis, and the Product Quality Assessment Aid.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00066-1

By:

Algorri, Marquerita;
Acharya, Ajay;
Bernstein, James;
Cauchon, Nina S.;
Chen, Xiao Hong;
Huynh-Ba, Kim;
Krantz, Carol;
Li, Tao;
Li, Yiwei;
McLamore, Sherita;
Roberts, Scott W.;
Schwinke, David;
Shah, Rakhi;
Schirmer, Andrea;
Strickland, Helen;
Tang, Kin;
Watson, Timothy

Publication type:

Article

Verification of nanoparticle formation, skin permeation, and apoptosis using nobiletin as a methoxyflavonoid derivative.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00065-2

By:

Inoue, Yutaka;
Ishizawa, Moe;
Itakura, Shoko;
Tanikawa, Takashi;
Todo, Hiroaki

Publication type:

Article

Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00064-3

By:

Yuk, Inn H.;
Koulis, Theo;
Doshi, Nidhi;
Gregoritza, Kathrin;
Hediger, Constanze;
Lebouc-Haefliger, Vanessa;
Giddings, Jamie;
Khan, Tarik A.

Publication type:

Article

Results from in vitro and in vivo studies evaluating the bioavailability, effects of food, and administration as crushed tablet suspension on vericiguat pharmacokinetics.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00063-4

By:

Becker, Corina;
Boettcher, Michael;
Muenster, Uwe;
Loewen, Stephanie;
Lobmeyer, Maximilian;
Mueck, Wolfgang

Publication type:

Article

Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00062-5

By:

Chun, Jonathan

Publication type:

Article

Technical transfer and commercialisation of lyophilised biopharmaceuticals — application of lyophiliser characterisation and comparability.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00059-0

By:

Cullen, Sean;
Walsh, Emma;
Gervasi, Valeria;
Khamar, Dikshitkumar;
McCoy, Timothy R.

Publication type:

Article

PLGA-based nanoparticles for the treatment of cancer: current strategies and perspectives.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00060-7

By:

Alvi, Maria;
Yaqoob, Azka;
Rehman, Kanwal;
Shoaib, Syed Muhammad;
Akash, Muhammad Sajid Hamid

Publication type:

Article

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM).

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00058-1

By:

Kemper, Christopher;
Behnam, Dariush;
Brothers, Shaun;
Wahlestedt, Claes;
Volmar, Claude-Henry;
Bennett, Daniel;
Hayward, Marshall

Publication type:

Article

Correction: Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM).

Published in:

2022

By:

Kemper, Christopher;
Behnam, Dariush;
Brothers, Shaun;
Wahlestedt, Claes;
Volmar, Claude-Henry;
Bennett, Daniel;
Hayward, Marshall

Publication type:

Correction Notice

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM).

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00058-1

By:

Kemper, Christopher;
Benham, Dariush;
Brothers, Shaun;
Wahlestedt, Claes;
Volmar, Claude-Henry;
Bennett, Daniel;
Hayward, Marshall

Publication type:

Article

Utilizing cross-product prior knowledge to rapidly de-risk chemical liabilities in therapeutic antibody candidates.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00057-2

By:

Jacobitz, Alex W.;
Rodezno, Wilfredo;
Agrawal, Neeraj J.

Publication type:

Article

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00054-5

By:

Zhang, Yumeng;
Zhao, Zhouming;
Wang, Kai;
Lyu, Kangjie;
Yao, Cai;
Li, Lin;
Shen, Xia;
Liu, Tengfei;
Guo, Xiaodi;
Li, Haiyan;
Wang, Wenshou;
Lai, Tsai-Ta

Publication type:

Article

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00054-5

By:

Zhang, Yumeng;
Zhao, Zhouming;
Wang, Kai;
Lyu, Kangjie;
Yao, Cai;
Li, Lin;
Shen, Xia;
Liu, Tengfei;
Guo, Xiaodi;
Li, Haiyan;
Wang, Wenshou;
Lai, Tsai-Ta

Publication type:

Article

Heat pre-treatment can abolish anti-drug antibody interference in ligand binding pharmacokinetic assays.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00056-3

By:

Poulsen, Svend;
Jørgensen, Louise;
Galle, Pia Søndergaard

Publication type:

Article

Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00052-7

By:

Wang, Xiaofeng;
Jamil, Khurram

Publication type:

Article

Understanding the implication of Kawakita model parameters using in-die force-displacement curve analysis for compacted and non-compacted API powders.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00053-6

By:

Rashid, Iyad;
Haddadin, Rula Raji;
Alkafaween, Ashaar Abdulsalam;
Alkaraki, Rawan Nayef;
Alkasasbeh, Rehan Mohammad

Publication type:

Article

The degradation of poloxamer 188 in buffered formulation conditions.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00055-4

By:

Chen, Wei;
Stolz, Siegfried;
Wegbecher, Vincent;
Parakkattel, Dixy;
Haeuser, Christina;
Oltra, Nuria Sancho;
Kishore, Ravuri S. K.;
Bond, Steven;
Bell, Christian;
Kopf, Robert

Publication type:

Article

Therapeutic effects of dracocephalum heterophyllum in collagen-induced arthritis.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-022-00051-8

By:

Wang, Yalan;
Lai, Dongming;
Geng, Yunyun;
Shang, Peng;
Wang, Pu

Publication type:

Article

Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00048-9

By:

Stüber, Jakob C.;
Rechberger, Karin F.;
Miladinović, Saša M.;
Pöschinger, Thomas;
Zimmermann, Tamara;
Villenave, Remi;
Eigenmann, Miro J.;
Kraft, Thomas E.;
Shah, Dhaval K.;
Kettenberger, Hubert;
Richter, Wolfgang F.

Publication type:

Article

Best practices for the development and fit-for-purpose validation of biomarker methods: a conference report.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00050-1

By:

Mathews, Joel;
Amaravadi, Lakshmi;
Eck, Steven;
Stevenson, Lauren;
Wang, Yow-Ming C.;
Devanarayan, Viswanath;
Allinson, John;
Lundsten, Kelly;
Gunsior, Michele;
Ni, Yan G.;
Pepin, Marc-Olivier;
Gagnon, Audrey;
Sheldon, Curtis;
Trampont, Paul C.;
Litwin, Virginia

Publication type:

Article

Development and validation of a headspace GC-MS method to evaluate the interconversion of impurities and the product quality of liquid hand sanitizers.

Published in:

AAPS Open, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s41120-021-00049-8

By:

Abrigo, Nicolas;
Ruzicka, Connie;
Faustino, Patrick;
Stiber, Neil;
NguyenPho, Agnes;
O'Connor, Thomas;
Shakleya, Diaa

Publication type:

Article

Works matching IS 23649534 AND DT 2022 AND VI 8 AND IP 1

Glycopeptide antibiotic drug stability in aqueous solution.

Meeting report: Advancing accelerated regulatory review with Real-Time Oncology Review (RTOR), Project Orbis, and the Product Quality Assessment Aid.

Verification of nanoparticle formation, skin permeation, and apoptosis using nobiletin as a methoxyflavonoid derivative.

Formulation mitigations for particle formation induced by enzymatic hydrolysis of polysorbate 20 in protein-based drug products: insights from a full-factorial longitudinal study.

Results from in vitro and in vivo studies evaluating the bioavailability, effects of food, and administration as crushed tablet suspension on vericiguat pharmacokinetics.

Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions.

Technical transfer and commercialisation of lyophilised biopharmaceuticals — application of lyophiliser characterisation and comparability.

PLGA-based nanoparticles for the treatment of cancer: current strategies and perspectives.

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL <sup>TM</sup>).

Correction: Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL <sup>TM</sup>).

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL <sup>TM</sup>).

Utilizing cross-product prior knowledge to rapidly de-risk chemical liabilities in therapeutic antibody candidates.

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-tycyclodextrin.

Heat pre-treatment can abolish anti-drug antibody interference in ligand binding pharmacokinetic assays.

Pharmacokinetic and pharmacodynamic analyses of terlipressin in patients with hepatorenal syndrome.

Understanding the implication of Kawakita model parameters using in-die force-displacement curve analysis for compacted and non-compacted API powders.

The degradation of poloxamer 188 in buffered formulation conditions.

Therapeutic effects of dracocephalum heterophyllum in collagen-induced arthritis.

Impact of charge patches on tumor disposition and biodistribution of therapeutic antibodies.

Best practices for the development and fit-for-purpose validation of biomarker methods: a conference report.

Development and validation of a headspace GC-MS method to evaluate the interconversion of impurities and the product quality of liquid hand sanitizers.