Works matching IS 21638306 AND DT 2025 AND VI 14 AND IP 6

Results: 13

A Multiple Imputation Workflow for Handling Missing Covariate Data in Pharmacometrics Modeling.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 991, doi. 10.1002/psp4.70039

By:

Vuong, My‐Luong;
Verbeke, Geert;
Dreesen, Erwin

Publication type:

Article

Effect of Cumulative Exposure on the Efficacy of Paroxetine: A Population Pharmacokinetic‐Pharmacodynamic and Machine Learning Analyses.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1119, doi. 10.1002/psp4.70032

By:

Shigetome, Keiichi;
Egashira, Tomoko;
Tomita, Tetsu;
Higa, Nagisa;
Iwashita, Kazuma;
Morita, Kazuya;
Nishimura, Miki;
Kaneko, Tetsuya;
Maeda, Hitoshi;
Yamada, Kazunori D.;
Kajiwara‐Morita, Ayami;
Oniki, Kentaro;
Yasui‐Furukori, Norio;
Saruwatari, Junji

Publication type:

Article

Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1108, doi. 10.1002/psp4.70030

By:

Huh, Yeamin;
Qiu, Ruolun;
Prybylski, John;
Wojciechowski, Jessica;
Wang, Yuchen;
Purohit, Vivek S.

Publication type:

Article

Development of a Heuristic Machine Analogy Method for Model Simplification With an Application to a Large‐Scale Model of Gi/Gs Signaling.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1098, doi. 10.1002/psp4.70029

By:

Yang, Liang;
Finlay, David;
Glass, Michelle;
Duffull, Stephen

Publication type:

Article

Mechanistic Physiologically Based Pharmacokinetic Modeling of Dry Powder and Nebulized Formulations of Orally Inhaled TMEM16A Potentiator GDC‐6988.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1087, doi. 10.1002/psp4.70027

By:

Zhu, Rui;
Sorrell, Ian;
Ma, Fang;
Ning, Miaoran;
Son, Yoen‐Ju;
She, Gaohong;
De Bruyn, Tom;
Galanter, Joshua;
Kassir, Nastya;
Owen, Ryan;
Jamei, Masoud;
Gardner, Iain;
Chen, Yuan

Publication type:

Article

Middle‐Out Physiologically Based Pharmacokinetic Modeling to Support Pediatric Dosing Recommendation for Alectinib.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1077, doi. 10.1002/psp4.70020

By:

van Donge, Tamara;
Guerini, Elena;
O'Jeanson, Amaury;
Parrott, Neil;
Devlin, Clare;
Stillhart, Cordula;
Djebli, Nassim

Publication type:

Article

A Model‐Based Approach to Evaluate Anti‐Drug Antibody Impact on Drug Exposure With Biologics: A Case Example With the CD3 T‐Cell Bispecific Cibisatamab.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1065, doi. 10.1002/psp4.70019

By:

Sanchez, Javier;
Pierrillas, Philippe B.;
Frey, Nicolas;
Lotz, Gregor P.;
Jönsson, Siv;
Friberg, Lena E.;
Frances, Nicolas

Publication type:

Article

Precision Medicine in Oncology: Imatinib Dosing in the Obese Cancer Population Using Virtual Clinical Trials.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1050, doi. 10.1002/psp4.70018

By:

Burhanuddin, Khairulanwar;
Mohammed, Afzal;
Burhanuddin, Nurul Afiqah;
Badhan, Raj K. S.

Publication type:

Article

A Pragmatic Approach to Handling Censored Data Below the Lower Limit of Quantification in Pharmacokinetic Modeling.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1042, doi. 10.1002/psp4.70015

By:

Wijk, Marie;
Wasmann, Roeland E.;
Jacobson, Karen R.;
Svensson, Elin M.;
Denti, Paolo

Publication type:

Article

Pharmacokinetic Model‐Informed Precision Dosing of Natalizumab in Multiple Sclerosis.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1032, doi. 10.1002/psp4.70014

By:

van den Berg, Stefan P. H.;
Toorop, Alyssa A.;
Hooijberg, Femke;
Wolbink, Gertjan;
Voelkner, Nivea M. F.;
Gelissen, Liza M. Y.;
Killestein, Joep;
van Kempen, Zoé L. E.;
Dorlo, Thomas P. C.;
Rispens, Theo

Publication type:

Article

Precision Dosing in Presence of Multiobjective Therapies by Integrating Reinforcement Learning and PK‐PD Models: Application to Givinostat Treatment of Polycythemia Vera.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1018, doi. 10.1002/psp4.70012

By:

De Carlo, Alessandro;
Tosca, Elena Maria;
Magni, Paolo

Publication type:

Article

Development of a Joint Tumor Size–Overall Survival Modeling and Simulation Framework Supporting Oncology Development Decision‐Making.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 1006, doi. 10.1002/psp4.70002

By:

Struemper, Herbert;
Rathi, Chetan;
Muliaditan, Morris;
Goulooze, Sebastiaan C.;
Franzese, Richard C.;
Mantero, Alejandro;
Melhem, Murad;
Post, Teun M.;
Visser, Sandra A. G.

Publication type:

Article

Issue Information.

Published in:: CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 6, p. 987, doi. 10.1002/psp4.13173
Publication type:: Article