Works matching IS 21638306 AND DT 2025 AND VI 14 AND IP 1

Results: 16

Is the GFR‐based scaling approach adequate for predicting pediatric renal clearance of drugs with passive tubular reabsorption? Insights from PBPK modeling.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 152, doi. 10.1002/psp4.13254

By:

Li, Sanwang;
Ye, Xuexin;
Wang, Qiushi;
Cheng, Zeneng;
Liu, Feiyan;
Xie, Feifan

Publication type:

Article

PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism?

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 130, doi. 10.1002/psp4.13249

By:

Henriot, Justine;
Dallmann, André;
Dupuis, François;
Perrier, Jérémy;
Frechen, Sebastian

Publication type:

Article

Population pharmacokinetic modeling of zavegepant, a calcitonin gene‐related peptide receptor antagonist, in healthy adults and patients with migraine.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 179, doi. 10.1002/psp4.13257

By:

Comisar, Craig M.;
Francis, Jose;
Hughes, Jim H.;
Bhardwaj, Rajinder;
Bertz, Richard;
Liu, Jing

Publication type:

Article

Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase‐CYP substrates.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 164, doi. 10.1002/psp4.13255

By:

Izat, Nihan;
Bolleddula, Jayaprakasam;
Carione, Pasquale;
Huertas Valentin, Leticia;
Jones, Robert S.;
Kulkarni, Priyanka;
Moss, Darren;
Peterkin, Vincent C.;
Tian, Dan‐Dan;
Treyer, Andrea;
Venkatakrishnan, Karthik;
Zientek, Michael A.;
Barber, Jill;
Houston, J. Brian;
Galetin, Aleksandra;
Scotcher, Daniel

Publication type:

Article

Vancomycin population pharmacokinetic models: Uncovering pharmacodynamic divergence amid clinicobiological resemblance.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 142, doi. 10.1002/psp4.13253

By:

Gandia, Peggy;
Chaiben, Sahira;
Fabre, Nicolas;
Concordet, Didier

Publication type:

Article

Low‐dimensional neural ordinary differential equations accounting for inter‐individual variability implemented in Monolix and NONMEM.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 5, doi. 10.1002/psp4.13265

By:

Bräm, Dominic Stefan;
Steiert, Bernhard;
Pfister, Marc;
Steffens, Britta;
Koch, Gilbert

Publication type:

Article

Population pharmacokinetics and pharmacodynamics of edoxaban in pediatric patients.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 118, doi. 10.1002/psp4.13248

By:

Zou, Peng;
Atluri, Akhilesh;
Chang, Peter;
Goedecke, Michael;
Leil, Tarek A.

Publication type:

Article

Physiology‐based pharmacokinetic model with relative transcriptomics to evaluate tissue distribution and receptor occupancy of anifrolumab.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 105, doi. 10.1002/psp4.13245

By:

Sharma, Pradeep;
Boulton, David W.;
Bertagnolli, Lynn N.;
Tang, Weifeng

Publication type:

Article

The population pharmacokinetics of dolutegravir co‐administered with rifampicin in Thai people living with HIV: Assessment of alternative dosing regimens.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 95, doi. 10.1002/psp4.13244

By:

Punyawudho, Baralee;
Chanruang, Anan;
Ueaphongsukkit, Thornthun;
Gatechompol, Sivaporn;
Ubolyam, Sasiwimol;
Cho, Yong Soon;
Shin, Jae Gook;
Avihingsanon, Anchalee

Publication type:

Article

To be or not to be, when synthetic data meet clinical pharmacology: A focused study on pharmacogenetics.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 82, doi. 10.1002/psp4.13240

By:

Woillard, Jean‐Baptiste;
Benoist, Clément;
Destere, Alexandre;
Labriffe, Marc;
Marchello, Giulia;
Josse, Julie;
Marquet, Pierre

Publication type:

Article

Nonlinear mixed‐effects modeling as a method for causal inference to predict exposures under desired within‐subject dose titration schemes.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 68, doi. 10.1002/psp4.13239

By:

Bartels, Christian;
Scauda, Martina;
Coello, Neva;
Dumortier, Thomas;
Bornkamp, Björn;
Moffa, Giusi

Publication type:

Article

Within‐chain parallelization—Giving Stan Jet Fuel for population modeling in pharmacometrics.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 52, doi. 10.1002/psp4.13238

By:

Davis, Casey;
Vaddady, Pavan

Publication type:

Article

Immunostimulatory/Immunodynamic model of mRNA‐1273 to guide pediatric vaccine dose selection.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 42, doi. 10.1002/psp4.13237

By:

Ivaturi, Vijay;
Attarwala, Husain;
Deng, Weiping;
Ding, Baoyu;
Schnyder Ghamloush, Sabine;
Girard, Bethany;
Iqbal, Javid;
Minnikanti, Saugandhika;
Zhou, Honghong;
Miller, Jacqueline;
Das, Rituparna

Publication type:

Article

Mathematical model of the relationship between pH holding time and erosive esophagitis healing rates.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 28, doi. 10.1002/psp4.13235

By:

Howden, Colin W.;
Scarpignato, Carmelo;
Leifke, Eckhard;
Mulford, Darcy J.;
Lahu, Gezim;
Facius, Axel;
Yuan, Yuhong;
Hunt, Richard

Publication type:

Article

A model‐based approach using GSK3772847, an anti‐interleukin‐33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and total target measurements after IV administration.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 17, doi. 10.1002/psp4.13234

By:

Berkhout, Jan;
Fairman, Dave;
van Noort, Martijn;
van Steeg, Tamara J.

Publication type:

Article

Issue Information.

Published in:: CPT: Pharmacometrics & Systems Pharmacology, 2025, v. 14, n. 1, p. 1, doi. 10.1002/psp4.13168
Publication type:: Article