Works in CPT: Pharmacometrics & Systems Pharmacology, 2022, Vol 11, Issue 12

Results: 13

Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1628, doi. 10.1002/psp4.12872

By:

Faraj, Alan;
Knudsen, Tom;
Desai, Shraddha;
Neuman, Linda;
Blouse, Grant E.;
Simonsson, Ulrika S. H.

Publication type:

Article

Evaluation of machine learning methods for covariate data imputation in pharmacometrics.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1638, doi. 10.1002/psp4.12874

By:

Bräm, Dominic Stefan;
Nahum, Uri;
Atkinson, Andrew;
Koch, Gilbert;
Pfister, Marc

Publication type:

Article

Conceptual and organizational barriers to quantitative systems pharmacology modeling of pathophysiological systemic drug hypotheses.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1556, doi. 10.1002/psp4.12873

By:

Gieschke, Ronald;
Carr, Robert

Publication type:

Article

Applying interpretable machine learning workflow to evaluate exposure–response relationships for large‐molecule oncology drugs.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1614, doi. 10.1002/psp4.12871

By:

Liu, Gengbo;
Lu, James;
Lim, Hong Seo;
Jin, Jin Yan;
Lu, Dan

Publication type:

Article

Comparing the applications of machine learning, PBPK, and population pharmacokinetic models in pharmacokinetic drug–drug interaction prediction.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1560, doi. 10.1002/psp4.12870

By:

Gill, Jaidip;
Moullet, Marie;
Martinsson, Anton;
Miljković, Filip;
Williamson, Beth;
Arends, Rosalinda H.;
Pilla Reddy, Venkatesh

Publication type:

Article

Bayesian forecasting of tumor size metrics and overall survival.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1604, doi. 10.1002/psp4.12869

By:

Krishnan, Sreenath M.;
Friberg, Lena E.

Publication type:

Article

Activity and perspective on quantitative modeling and simulation in Japan: Update from the Pharmaceuticals and Medical Devices Agency.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1552, doi. 10.1002/psp4.12868

By:

Kijima, Shinichi;
Yoshida, Shuya;
Ochiai, Yoshinori

Publication type:

Article

Issue Information.

Published in:: CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1539, doi. 10.1002/psp4.12659
Publication type:: Article

A perspective on the current use of the phase distribution model for predicting milk‐to‐plasma drug concentration ratio.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1547, doi. 10.1002/psp4.12865

By:

Zhang, Mian;
Sychterz, Caroline;
Chang, Ming;
Huang, Lu;
Schmidt, Brian J.;
Gaohua, Lu

Publication type:

Article

PBPK perspective on alternative CYP3A4 inducers for rifampin.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1543, doi. 10.1002/psp4.12864

By:

Chen, Kuan‐Fu;
Jones, Hannah M.

Publication type:

Article

Dose/exposure–response modeling in dose titration trials: Overcoming the titration paradox.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1592, doi. 10.1002/psp4.12863

By:

Kristensen, Niels Rode;
Agersø, Henrik

Publication type:

Article

Population pharmacokinetic‐pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1578, doi. 10.1002/psp4.12862

By:

Hayato, Seiichi;
Takenaka, Osamu;
Sreerama Reddy, Sree Harsha;
Landry, Ishani;
Reyderman, Larisa;
Koyama, Akihiko;
Swanson, Chad;
Yasuda, Sanae;
Hussein, Ziad

Publication type:

Article

A case‐study of model‐informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 12, p. 1569, doi. 10.1002/psp4.12866

By:

Knöchel, Jane;
Nilsson, Catarina;
Carlsson, Björn;
Wernevik, Linda;
Hofherr, Alexis;
Gennemark, Peter;
Jansson‐Löfmark, Rasmus;
Isaksson, Rikard;
Rydén‐Bergsten, Tina;
Hamrén, Bengt;
Rekić, Dinko

Publication type:

Article