Works matching IS 2160763X AND DT 2021 AND VI 10

Results: 163

Influence of CYP2C19 Polymorphisms on the Pharmacokinetics of Omeprazole in Elderly Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1469, doi. 10.1002/cpdd.966

By:

Na, Joo Young;
Jeon, Inseung;
Yoon, Jangsoo;
Choi, Yewon;
Yoon, Seo Hyun;
Yu, Kyung‐Sang;
Chung, Jae‐Yong

Publication type:

Article

Effect of Upadacitinib on the Pharmacokinetics of Rosuvastatin or Atorvastatin in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1335, doi. 10.1002/cpdd.957

By:

Mohamed, Mohamed‐Eslam F.;
Coppola, Sheryl;
Feng, Tian;
Camp, Heidi S.;
Kim, Elaine;
Othman, Ahmed A.

Publication type:

Article

A Phase 1 Open‐Label, Fixed‐Sequence Pharmacokinetic Drug Interaction Trial to Investigate the Effect of Cannabidiol on the CYP1A2 Probe Caffeine in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1279, doi. 10.1002/cpdd.950

By:

Thai, Ching;
Tayo, Bola;
Critchley, David

Publication type:

Article

Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK‐30, and From Red Ginseng Extract in Healthy Korean Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1358, doi. 10.1002/cpdd.949

By:

Ban, Mu Seong;
Kim, Yun;
Lee, Sunyoung;
Han, ByongYeul;
Yu, Kyung‐Sang;
Jang, In‐Jin;
Chung, Hong Keun;
Lee, SeungHwan

Publication type:

Article

Impact of Paroxetine, a Strong CYP2D6 Inhibitor, on SPN‐812 (Viloxazine Extended‐Release) Pharmacokinetics in Healthy Adults.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1365, doi. 10.1002/cpdd.948

By:

Wang, Zhao;
Kosheleff, Alisa R.;
Adeojo, Lilian W.;
Odebo, Oyinkansola;
Adewole, Toyin;
Qin, Peibing;
Maletic, Vladimir;
Schwabe, Stefan;
Nasser, Azmi

Publication type:

Article

A Bioequivalence Study of Avanafil in Healthy Chinese Male Subjects Under Fasting and Fed Conditions: Results of a Randomized, Open‐Label, Single‐Dose, 2‐Sequence, 2‐Period Crossover Study.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1495, doi. 10.1002/cpdd.998

By:

Ren, Xiuhua;
Yu, Hengyi;
Qi, Xingxing;
Chen, Qian;
Yang, Jingwen;
Fang, Yinian;
Lei, Yongfang;
Zhang, Donglin;
Zuo, Qin;
Liu, Dong

Publication type:

Article

An Open‐Label, Randomized, 2‐Way, Crossover Bioequivalence Study of Cefradine Capsules in Healthy Chinese Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1478, doi. 10.1002/cpdd.991

By:

Lai, Xiuping;
Ye, Suiwen;
Chen, Liuhan;
Chen, Junyi;
Zhang, Nan;
Zhang, Yiwen;
Wu, Junyan;
Yao, Herui

Publication type:

Article

Pharmacokinetics and Bioequivalence Evaluation of 2 Formulations of Tenofovir Alafenamide.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1519, doi. 10.1002/cpdd.985

By:

Li, Zhihui;
Liu, Jingyan;
Ju, Gehang;
Yan, Keyu;
Mao, Yong;
Liu, Qingchun;
Yang, Xinlu;
Zhang, Rong;
Qiu, Wen

Publication type:

Article

Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Omecamtiv Mecarbil.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1442, doi. 10.1002/cpdd.969

By:

Trivedi, Ashit;
Oberoi, Rajneet K.;
Mackowski, Mia;
Jafarinasabian, Pegah;
Zhang, Hanze;
Flach, Stephen;
Hutton, Shauna;
Abbasi, Siddique;
Dutta, Sandeep;
Lee, Edward

Publication type:

Article

Pharmacokinetics and Bioequivalence Study of a New Branded Generic Moxifloxacin Tablet Among Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1514, doi. 10.1002/cpdd.964

By:

Amran, Atiqah;
Tan, Ching Yee;
Tan, Ka‐Liong;
Ho, Ranald Malcom;
Anand, Anil Kumar;
Leong, Chuei Wuei

Publication type:

Article

First‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Pirepemat, a Cortical Enhancer, in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1485, doi. 10.1002/cpdd.959

By:

Rein‐Hedin, Erik;
Sjöberg, Folke;
Waters, Susanna;
Sonesson, Clas;
Waters, Nicholas;
Huss, Fredrik;
Tedroff, Joakim

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1405, doi. 10.1002/cpdd.839
Publication type:: Article

Surveys/Research Exploring Japanese Phase I Studies in Global Drug Development: Are They Necessary Prior to Joining Global Clinical Trials?

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1410, doi. 10.1002/cpdd.1044

By:

Hirano, Masaru;
Yamada, Masanori;
Tanaka, Toshiaki;
Koue, Toshiko;
Saito, Tomohisa;
Higashimori, Mitsuo;
Ochiai, Hisao;
Yamamoto, Junichi;
Yaguchi, Saori;
Mita, Sachiko;
Hara, Katsutoshi

Publication type:

Article

Clinical Pharmacokinetics of Daprodustat: Results of an Absorption, Distribution, and Excretion Study With Intravenous Microtracer and Concomitant Oral Doses for Bioavailability Determination.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1419, doi. 10.1002/cpdd.1029

By:

Mahar, Kelly M.;
Caltabiano, Stephen;
Andrews, Susan;
Ramanjineyulu, Bandi;
Chen, Liangfu;
Young, Graeme;
Pereira, Adrian;
Lindsay, Alistair C.;
van den Berg, Frans;
Cobitz, Alexander R.

Publication type:

Article

Lack of a Clinically Meaningful Drug Interaction Between the HIV‐1 Antiretroviral Agents Islatravir, Dolutegravir, and Tenofovir Disoproxil Fumarate.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1432, doi. 10.1002/cpdd.1026

By:

Rudd, Deanne Jackson;
Zhang, Saijuan;
Fillgrove, Kerry L.;
Fox‐Bosetti, Sabrina;
Matthews, Randolph P.;
Friedman, Evan;
Armas, Danielle;
Stoch, S. Aubrey;
Iwamoto, Marian

Publication type:

Article

Single‐ and Multiple‐Dose Pharmacokinetics and Pharmacodynamics of PN‐943, a Gastrointestinal‐Restricted Oral Peptide Antagonist of α4β7, in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1263, doi. 10.1002/cpdd.946

By:

Modi, Nishit B.;
Cheng, Xiaoli;
Mattheakis, Larry;
Hwang, Ching‐Chang;
Nawabi, Roya;
Liu, David;
Gupta, Suneel

Publication type:

Article

A Euglycemic Glucose Clamp Study to Evaluate the Bioavailability of LY2963016 Relative to Insulin Glargine in Healthy Chinese Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1452, doi. 10.1002/cpdd.1014

By:

Liu, Hui;
Wang, Feng;
Ji, Yongjia;
Ma, Tianyang;
Li, Hongying;
Linnebjerg, Helle;
Chua, Laiyi;
Tham, Lai San;
Yu, Yerong

Publication type:

Article

Randomized, Double‐Blind, Controlled Study to Evaluate Safety and Pharmacokinetics of Single Ascending Doses of ASP5354, an Investigational Imaging Product, in Healthy Adult Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1460, doi. 10.1002/cpdd.1013

By:

Murase, Tosei;
Takizawa, Masaomi;
Galitz, Lawrence;
Flach, Stephen;
Murray, Valene;
Gufford, Brandon;
Suwa, Akira

Publication type:

Article

Population Pharmacokinetic Model Development and Simulation for Recombinant Erwinia Asparaginase Produced in Pseudomonas fluorescens (JZP‐458).

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 12, p. 1503, doi. 10.1002/cpdd.1002

By:

Lin, Tong;
Dumas, Todd;
Kaullen, Josh;
Berry, N. Seth;
Choi, Mi Rim;
Zomorodi, Katie;
Silverman, Jeffrey A.

Publication type:

Article

Base and Covariate Population Pharmacokinetic Analyses of Dupilumab in Adolescents and Children ≥6 to <12 Years of Age Using Phase 3 Data.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1345, doi. 10.1002/cpdd.986

By:

Kovalenko, Pavel;
Kamal, Mohamed A.;
Davis, John D.;
Huniti, Nidal;
Xu, Christine;
Bansal, Ashish;
Shumel, Brad;
DiCioccio, A. Thomas

Publication type:

Article

Effects of Postoperative Day and NR1I2 on Tacrolimus Clearance in Chinese Liver Transplant Recipients—A Population Model Approach.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1385, doi. 10.1002/cpdd.971

By:

Lu, Yanxia;
Xu, Li;
Cui, Jianrong;
Shen, Su;
Li, Xingang

Publication type:

Article

Population Pharmacokinetic Analyses of Ertugliflozin in Select Ethnic Populations.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1297, doi. 10.1002/cpdd.970

By:

Fediuk, Daryl J.;
Sahasrabudhe, Vaishali;
Dawra, Vikas Kumar;
Zhou, Susan;
Sweeney, Kevin

Publication type:

Article

The Pharmacokinetics of Triheptanoin and Its Metabolites in Healthy Subjects and Patients With Long‐Chain Fatty Acid Oxidation Disorders.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1325, doi. 10.1002/cpdd.944

By:

Lee, Sun Ku;
Gupta, Manju;
Shi, Jack;
McKeever, Kathleen

Publication type:

Article

Mechanistic Considerations About an Unexpected Ramipril Drug‐Drug Interaction in the Development of a Triple Fixed‐Dose Combination Product Containing Ramipril, Amlodipine, and Atorvastatin.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1307, doi. 10.1002/cpdd.930

By:

Hermann, Robert;
Gundlach, Kristina;
Seiler, Dan

Publication type:

Article

Pharmacokinetic Interaction Among Ezetimibe, Rosuvastatin, and Telmisartan.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1290, doi. 10.1002/cpdd.926

By:

Huh, Ki Young;
Lee, Sang Won;
Lee, Si Beum;
Kim, Kyung Tae;
Jang, In‐Jin;
Lee, SeungHwan

Publication type:

Article

Pharmacokinetics of Opicapone and Its Metabolites in Healthy White and Chinese Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1316, doi. 10.1002/cpdd.922

By:

Xue, Wei;
Tan, Yan;
Liu, Yue;
Xu, Changjiang;
Cong, Duanduan;
Zhong, Liping;
Song, Jie;
Hui, Aimin;
Qi, Wenyuan;
Wang, Juan;
Liu, Xiaohui;
Li, Kexin

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1249, doi. 10.1002/cpdd.838
Publication type:: Article

Should Estimated Glomerular Filtration Rate Be Adjusted for Race?

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1254, doi. 10.1002/cpdd.1030
Publication type:: Article

Phase 1 Study Evaluating the Effects of the Proton Pump Inhibitor Rabeprazole and Food on the Pharmacokinetics of Lorlatinib in Healthy Participants.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1395, doi. 10.1002/cpdd.1000

By:

Xu, Huiping;
O'Gorman, Melissa T.;
Nepal, Sunil;
James, Lee P.;
Ginman, Katherine;
Pithavala, Yazdi K.

Publication type:

Article

Pharmacokinetics and Use‐Testing of Apalutamide Prepared in Aqueous Food Vehicles for Alternative Administration.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 11, p. 1375, doi. 10.1002/cpdd.1001

By:

Yu, Alex;
Erba, Maura;
Hazra, Anasuya

Publication type:

Article

Effect of Silymarin Treatment on Circulating Bilirubin and Cardiovascular Disease Risk Factors in Healthy Men: A Single‐Blind, Randomized Crossover Trial.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1156, doi. 10.1002/cpdd.962

By:

Vidimce, Josif;
Pennell, Evan Noel;
Foo, Maxmilian;
Shiels, Ryan Graeme;
Shibeeb, Sapha;
Watson, Michael;
Bulmer, Andrew Cameron

Publication type:

Article

Results of a Dose‐Finding Phase 1b Study of Subcutaneous Atezolizumab in Patients With Locally Advanced or Metastatic Non–Small Cell Lung Cancer.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1142, doi. 10.1002/cpdd.936

By:

Felip, Enriqueta;
Burotto, Mauricio;
Zvirbule, Zanete;
Herraez‐Baranda, Luis A.;
Chanu, Pascal;
Kshirsagar, Smita;
Maiya, Vidya;
Chan, Phyllis;
Pozzi, Emanuela;
Marchand, Mathilde;
Monchalin, Marion;
Tanaka, Kunihiko;
Tosti, Nadia;
Wang, Bei;
Restuccia, Eleonora

Publication type:

Article

Effect of Memantine on QT/QTc Interval in a Healthy Korean Population.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1209, doi. 10.1002/cpdd.931

By:

Park, Jin‐Woo;
Kim, Kyoung‐Ah;
Park, Ji‐Young

Publication type:

Article

Safety, Pharmacokinetics, Pharmacodynamics, and Formulation of Liver‐Distributed Farnesoid X‐Receptor Agonist TERN‐101 in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1198, doi. 10.1002/cpdd.960

By:

Wang, Yujin;
Crittenden, Daria B.;
Eng, Clarence;
Zhang, Qiong;
Guo, Pengfei;
Chung, Diana;
Fenaux, Martijn;
Klucher, Kevin;
Jones, Christopher;
Jin, Feng;
Quirk, Erin;
Charlton, Michael R.

Publication type:

Article

Bioequivalence Study of Oral Suspension and Intravenous Formulation of Edaravone in Healthy Adult Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1188, doi. 10.1002/cpdd.952

By:

Shimizu, Hidetoshi;
Nishimura, Yukiko;
Shiide, Youichi;
Yoshida, Kaori;
Hirai, Manabu;
Matsuda, Munetomo;
Nakamaru, Yoshinobu;
Kato, Yuichiro;
Kondo, Kazuoki

Publication type:

Article

Randomized, Open‐Label, Single‐Dose, Parallel‐Group Pharmacokinetic Study of PF‐06410293 (adalimumab‐afzb), an Adalimumab Biosimilar, by Subcutaneous Dosing Using a Prefilled Syringe or a Prefilled Pen in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1166, doi. 10.1002/cpdd.939

By:

Cox, Donna S.;
Alvarez, Daniel F.;
Bock, Amy E.;
Cronenberger, Carol L.

Publication type:

Article

Evaluation of the Potential Effect of Iptakalim Hydrochloride on the QT Interval in Single‐ and Multiple‐Ascending‐Dose Studies Using Concentration‐QTc Analysis.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1231, doi. 10.1002/cpdd.945

By:

Bai, Nan;
Wang, Jin;
Che, Haoyue;
Wang, Hai;
Wang, Rui;
Cai, Yun

Publication type:

Article

Evaluation of Pharmacokinetics, Safety, and Drug‐Drug Interactions of an Oral Suspension of Edaravone in Healthy Adults.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1174, doi. 10.1002/cpdd.925

By:

Shimizu, Hidetoshi;
Nishimura, Yukiko;
Shiide, Yoichi;
Matsuda, Hideaki;
Akimoto, Makoto;
Matsuda, Munetomo;
Nakamaru, Yoshinobu;
Kato, Yuichiro;
Kondo, Kazuoki

Publication type:

Article

Evaluation of the Bioequivalence of Acarbose in Healthy Chinese People.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1225, doi. 10.1002/cpdd.921

By:

Chen, Yan;
Guo, Fahao;
Wang, Xin;
Liu, LuYao;
Yang, Can;
Xiong, YuQing;
Zhang, Hong

Publication type:

Article

Safety of a Novel Weight Loss Combination Product Containing Orlistat and Acarbose.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1242, doi. 10.1002/cpdd.920

By:

Grudén, Stefan;
Forslund, Anders;
Alderborn, Göran;
Söderhäll, Arvid;
Hellström, Per M.;
Holmbäck, Ulf

Publication type:

Article

Pharmacokinetics and Safety of Dapoxetine Hydrochloride in Healthy Chinese Men: Impact of Dose and High‐Fat Meal.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1216, doi. 10.1002/cpdd.919

By:

Liu, Jingyan;
Li, Zhihui;
Yan, Keyu;
Ju, Gehang;
Qiu, Wen

Publication type:

Article

Meta‐analysis of Pharmacokinetic/Pharmacodynamic Results of 3 Phase 1 Studies with Biosimilar Pegfilgrastim.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1130, doi. 10.1002/cpdd.1005

By:

Gattu, Sreekanth;
Wang, Jessie;
Bellon, Anne;
Schelcher, Celine;
Nakov, Roumen;
Arani, Ramin

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, p. i, doi. 10.1002/cpdd.716
Publication type:: Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1121, doi. 10.1002/cpdd.837
Publication type:: Article

Tirbanibulin: A New Topical Therapy for Actinic Keratoses With a Novel Mechanism of Action and Improved Ease of Use.

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, n. 10, p. 1126, doi. 10.1002/cpdd.1024
Publication type:: Article

ACCP Abstract Booklet.

Published in:: Clinical Pharmacology in Drug Development, 2021, v. 10, p. 1, doi. 10.1002/cpdd.1004
Publication type:: Article

GLPG1205, a GPR84 Modulator: Safety, Pharmacokinetics, and Pharmacodynamics in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 9, p. 994, doi. 10.1002/cpdd.955

By:

Timmis, Helen;
Van Kaem, Tim;
Desrivot, Julie;
Dupont, Sonia;
Meuleners, Luc;
Beetens, Johan;
Helmer, Eric;
Santermans, Eva;
Huettner, Silke

Publication type:

Article

Effects of Lemborexant on the Pharmacokinetics of Oral Contraceptives: Results From a Phase 1 Drug‐Drug Interaction Study in Healthy Females.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 9, p. 1089, doi. 10.1002/cpdd.953

By:

Landry, Ishani;
Aluri, Jagadeesh;
Hall, Nancy;
Filippov, Gleb;
Dayal, Satish;
Moline, Margaret;
Reyderman, Larisa

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Abacavir/Dolutegravir/Lamivudine Combination Tablets in Healthy Japanese Study Participants.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 9, p. 985, doi. 10.1002/cpdd.996

By:

Singh, Rajendra P.;
Adkison, Kimberly;
Wolstenholme, Allen;
Hopking, Judy;
Wynne, Brian

Publication type:

Article

Apixaban Single‐Dose Pharmacokinetics, Bioavailability, Renal Clearance, and Pharmacodynamics Following Intravenous and Oral Administration.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 9, p. 974, doi. 10.1002/cpdd.990

By:

Frost, Charles;
Garonzik, Samira;
Shenker, Andrew;
Barrett, Yu Chen;
LaCreta, Frank

Publication type:

Article