Works matching IS 2160763X AND DT 2018 AND VI 7

Results: 108

Pharmacokinetics, Excretion, and Mass Balance of [<sup>14</sup>C]‐Batefenterol Following a Single Microtracer Intravenous Dose (Concomitant to an Inhaled Dose) or Oral Dose of Batefenterol in Healthy Men.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 901, doi. 10.1002/cpdd.616

By:

Ambery, Claire;
Young, Graeme;
Fuller, Teresa;
Lazaar, Aili L.;
Pereira, Adrian;
Hughes, Adam;
Ramsay, David;
den Berg, Frans;
Daley‐Yates, Peter

Publication type:

Article

Assessment of the Effects of Age and Renal Function on Pharmacokinetics of Bazedoxifene in Postmenopausal Women.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 920, doi. 10.1002/cpdd.607

By:

McKeand, William;
Ermer, James;
Korth‐Bradley, Joan

Publication type:

Article

Amenamevir: Studies of Potential CYP3A‐Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 844, doi. 10.1002/cpdd.586

By:

Adeloye, Temitope;
Sahgal, Omair;
Puri, Adeep;
Warrington, Steve;
Endo, Takamasa;
Dennison, Jeremy;
Johnston, Atholl

Publication type:

Article

Amenamevir: Studies of Potential CYP2C8‐ and CYP2B6‐Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 860, doi. 10.1002/cpdd.578

By:

Dennison, Jeremy;
Puri, Adeep;
Warrington, Steven;
Endo, Takamasa;
Adeloye, Temitope;
Johnston, Atholl

Publication type:

Article

Effects of Intrinsic Factors on the Clinical Pharmacokinetics of Vortioxetine.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 880, doi. 10.1002/cpdd.577

By:

Chen, Grace;
Nomikos, George G.;
Affinito, John;
Jacobson, William;
Zhao, Zhen;
Wang, Shining;
Xie, Jinhui

Publication type:

Article

A Study of the Potential Interaction Between Bazedoxifene and Atorvastatin in Healthy Postmenopausal Women.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 911, doi. 10.1002/cpdd.458

By:

McKeand, William;
Baird‐Bellaire, Susan;
Ermer, James;
Patat, Alain

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Luseogliflozin, a Selective SGLT2 Inhibitor, in Japanese Patients With Type 2 Diabetes With Mild to Severe Renal Impairment.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 820, doi. 10.1002/cpdd.456

By:

Samukawa, Yoshishige;
Haneda, Masakazu;
Seino, Yutaka;
Sasaki, Takashi;
Fukatsu, Atsushi;
Kubo, Yusuke;
Sato, Yuri;
Sakai, Soichi

Publication type:

Article

Bioequivalence of Canakinumab Injected Subcutaneously via an Autoinjector Device or a Prefilled Safety Syringe Device in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 829, doi. 10.1002/cpdd.455

By:

Anumolu, SivaNaga S.;
Lindgren, Sam;
Vemula, Janardhana;
Floch, David;
Reynolds, Christine;
Wallny, Hans‐Joachim;
Sun, Haiying

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2018, v. 7, p. i, doi. 10.1002/cpdd.621
Publication type:: Article

Applications of Modeling & Simulation.

Published in:: Clinical Pharmacology in Drug Development, 2018, v. 7, p. 1, doi. 10.1002/cpdd.610
Publication type:: Article

Ropivacaine Wound Infiltration for Pain Management After Breast Cancer Mastectomy: A Population Pharmacokinetic Analysis.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 811, doi. 10.1002/cpdd.452

By:

Riff, Camille;
Guilhaumou, Romain;
Marsot, Amelie;
Beaussier, Marc;
Cohen, Monique;
Blin, Olivier;
Francon, Daniel

Publication type:

Article

Confirmation of the Cardiac Safety of PGF<sub>2α</sub> Receptor Antagonist OBE022 in a First‐in‐Human Study in Healthy Subjects, Using Intensive ECG Assessments.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 889, doi. 10.1002/cpdd.447

By:

Täubel, Jörg;
Lorch, Ulrike;
Coates, Simon;
Fernandes, Sara;
Foley, Paul;
Ferber, Georg;
Gotteland, Jean‐Pierre;
Pohl, Oliver

Publication type:

Article

Risk Factor for Diabetes Mellitus and High Blood Glucose With HMG‐CoA Reductase Inhibitors Using a Postmarketing Surveillance Database in Japan.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 800, doi. 10.1002/cpdd.444

By:

Hashiguchi, Masayuki;
Maruyama, Junya;
Shimizu, Mikiko;
Takahashi, Daichi;
Shiga, Tsuyoshi

Publication type:

Article

Comparison of Changes in the Lipid Profiles of Eastern Chinese Postmenopausal Women With Early‐Stage Breast Cancer Treated With Different Aromatase Inhibitors: A Retrospective Study.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 837, doi. 10.1002/cpdd.420

By:

Tian, Wei;
Wu, Miaowei;
Deng, Yongchuan

Publication type:

Article

A Prospective Randomized, Double‐Blind, Two‐Period Crossover Pharmacokinetic Trial Comparing Green Coffee Bean Extract—A Botanically Sourced Caffeine—With a Synthetic USP Control.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 871, doi. 10.1002/cpdd.451

By:

Morton, Kayce;
Knight, Katelin;
Kalman, Douglas;
Hewlings, Susan

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 795, doi. 10.1002/cpdd.405
Publication type:: Article

Pharmacokinetics and Target Attainment of Ceftobiprole in Asian and Non‐Asian Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 781, doi. 10.1002/cpdd.465

By:

Muller, A. E.;
Punt, N.;
Engelhardt, M.;
Schmitt‐Hoffmann, A. H.;
Mouton, J. W.

Publication type:

Article

Evaluation of Eluxadoline Effect on Cardiac Repolarization.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 727, doi. 10.1002/cpdd.453

By:

Bonifacio, Laura;
Hunt, Thomas L.;
McIntyre, Gail;
Dove, Leonard S.;
Covington, Paul S.

Publication type:

Article

Pharmacologic and Pharmacodynamic Equivalence of 2 Formulations of Orlistat.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 773, doi. 10.1002/cpdd.457

By:

Johnson, Steven;
Schwartz, Susan M.

Publication type:

Article

Tracking the Sugar Rush: Incorporating Continuous Glucose Monitoring Into Multisite Early Clinical Research With Type 2 Diabetes Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 676, doi. 10.1002/cpdd.437

By:

Paglialunga, Sabina;
Morimoto, Bruce H.;
de la Peña, Amparo;
Fortier, Caroline

Publication type:

Article

Evaluation of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy After Single and Multiple Dosings of LY3016859 in Healthy Subjects and Patients With Diabetic Nephropathy.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 759, doi. 10.1002/cpdd.436

By:

Sloan‐Lancaster, Joanne;
Raddad, Eyas;
Deeg, Mark A.;
Eli, Michelle;
Flynt, Amy;
Tumlin, James

Publication type:

Article

Odanacatib Pharmacokinetics Comparison Between Chinese and Non‐Chinese Postmenopausal Women.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 744, doi. 10.1002/cpdd.434

By:

Chen, Xia;
Jiang, Ji;
Hu, Pei;
Zajic, Stefan;
Liu, Wen;
McCrea, Jacqueline;
Liu, Fang;
Witter, Rose;
Mangin, Eric;
Stoch, S. Aubrey

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate in Elderly Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 788, doi. 10.1002/cpdd.426

By:

Flanagan, Shawn D.;
Minassian, Sonia L.;
Prokocimer, Philippe

Publication type:

Article

Effects of Milk or Apple Juice Ingestion on the Pharmacokinetics of Elvitegravir and Cobicistat in Healthy Japanese Male Volunteers: A Randomized, Single‐Dose, Three‐Way Crossover Study.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 737, doi. 10.1002/cpdd.425

By:

Yonemura, Takuma;
Okada, Nozomi;
Sagane, Koichi;
Okamiya, Kazuhiro;
Ozaki, Hideki;
Iida, Toshiaki;
Yamada, Hiroyuki;
Yagura, Hiroki

Publication type:

Article

A Pharmacokinetic Study of an Ibuprofen Topical Patch in Healthy Male and Female Adult Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 684, doi. 10.1002/cpdd.423

By:

Lewis, Fraser;
Connolly, Mark P.;
Bhatt, Aomesh

Publication type:

Article

Population Pharmacokinetics of Levofloxacin in Plasma and Bone of Patients Undergoing Hip or Knee Surgery.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 692, doi. 10.1002/cpdd.418

By:

Gergs, Ulrich;
Ihlefeld, Dorothea;
Clauss, Tobias;
Weiss, Michael;
Pönicke, Klaus;
Hofmann, Gunther O.;
Neumann, Joachim

Publication type:

Article

Pharmacokinetics and Safety of Mavatrep (JNJ‐39439335), a TRPV1 Antagonist in Healthy Japanese and Caucasian Men: A Double‐Blind, Randomized, Placebo‐Controlled, Sequential‐Group Phase 1 Study.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 712, doi. 10.1002/cpdd.413

By:

Manitpisitkul, Prasarn;
Shalayda, Kevin;
Russell, Lucille;
Sanga, Panna;
Solanki, Bhavna;
Caruso, Joseph;
Iwaki, Yuki;
Moyer, John A.

Publication type:

Article

Bioavailability and Pharmacokinetics of TRPV1 Antagonist Mavatrep (JNJ‐39439335) Tablet and Capsule Formulations in Healthy Men: Two Open‐Label, Crossover, Single‐Dose Phase 1 Studies.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 699, doi. 10.1002/cpdd.412

By:

Manitpisitkul, Prasarn;
Shalayda, Kevin;
Russell, Lucille;
Sanga, Panna;
Williams, Yinka;
Solanki, Bhavna;
Caruso, Joseph;
Moyer, John A.

Publication type:

Article

Single‐Dose Pharmacokinetics of Oral Cannabidiol Following Administration of PTL101: A New Formulation Based on Gelatin Matrix Pellets Technology.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 751, doi. 10.1002/cpdd.408

By:

Atsmon, Jacob;
Heffetz, Daphna;
Deutsch, Lisa;
Deutsch, Frederic;
Sacks, Hagit

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2018, v. 7, n. 7, p. 671, doi. 10.1002/cpdd.404
Publication type:: Article

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Mirogabalin When Coadministered With Lorazepam, Zolpidem, Tramadol, or Ethanol: Results From Drug‐Drug Interaction Studies in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 597, doi. 10.1002/cpdd.582

By:

Jansen, Mendel;
Mendell, Jeanne;
Currie, Alexander;
Dow, James;
He, Ling;
Merante, Domenico;
Dishy, Victor;
Ishizuka, Hitoshi;
Zahir, Hamim

Publication type:

Article

Pharmacokinetics of Perampanel in Healthy Korean, White, and Japanese Adult Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 613, doi. 10.1002/cpdd.581

By:

Tabuchi, Hiroko;
Shiba, Sari;
Yasuda, Sanae;
Ohnishi, Akihiro;
Shin, Jae‐Gook

Publication type:

Article

Pharmacokinetic Characteristics of Tofacitinib in Adult Patients With Moderate to Severe Chronic Plaque Psoriasis.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 587, doi. 10.1002/cpdd.471

By:

Ma, Guangli;
Xie, Rujia;
Strober, Bruce;
Langley, Richard;
Ito, Kaori;
Krishnaswami, Sriram;
Wolk, Robert;
Valdez, Hernan;
Rottinghaus, Scott;
Tallman, Anna;
Gupta, Pankaj

Publication type:

Article

Effects of High‐ and Low‐Fat Meals on the Pharmacokinetics of Ozanimod, a Novel Sphingosine‐1‐Phosphate Receptor Modulator.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 634, doi. 10.1002/cpdd.409

By:

Tran, Jonathan Q.;
Hartung, Jeffrey P.;
Tompkins, Cindy‐Ann;
Frohna, Paul A.

Publication type:

Article

Pharmacokinetic Interaction Between Fingolimod and Carbamazepine in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 575, doi. 10.1002/cpdd.459

By:

David, Olivier J.;
Behrje, Rhett;
Pal, Parasar;
Hara, Hisanori;
Lates, Christian D.;
Schmouder, Robert

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of Lamotrigine Chewable/Dispersible Tablet Following Repeat‐Dose Administration in Healthy Chinese Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 627, doi. 10.1002/cpdd.449

By:

Li, Yan;
Zhang, Fan;
Xu, Yanmei;
Hu, Joice;
Li, Huafang

Publication type:

Article

A Randomized, Placebo‐Controlled, Double‐Blind Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Repeated Doses of Mirogabalin in Healthy Asian Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 661, doi. 10.1002/cpdd.448

By:

Jansen, Mendel;
Warrington, Steven;
Dishy, Victor;
Ohwada, Shoichi;
Johnson, Lisa;
Brown, Karen;
Ishizuka, Hitoshi

Publication type:

Article

Safety, Pharmacokinetics, and Immunogenicity of Obiltoxaximab After Intramuscular Administration to Healthy Humans.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 652, doi. 10.1002/cpdd.410

By:

Nagy, Christa F.;
Leach, Timothy S.;
King, Alex;
Guttendorf, Robert

Publication type:

Article

Formulation and In Vitro, In Vivo Correlation Between Two Candesartan Cilexetil Tablets.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 621, doi. 10.1002/cpdd.460

By:

Zaid, Abdel Naser;
Radwan, Asma;
Jaradat, Nidal;
Mousa, Ayman;
Ghazal, Nadia;
Bustami, Rana

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 565, doi. 10.1002/cpdd.403
Publication type:: Article

Categorization of Abuse Potential–Related Adverse Events.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 569, doi. 10.1002/cpdd.394

By:

Sellers, Edward M.;
Romach, Myroslava K.

Publication type:

Article

A Thorough QT Study to Evaluate the Effects of Supratherapeutic Doses of Ledipasvir on the QTc Interval in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 6, p. 641, doi. 10.1002/cpdd.390

By:

German, Polina;
Mathias, Anita;
Brainard, Diana M.;
Song, Qinghua;
Ling, John;
Kearney, Brian P.

Publication type:

Article

Systemic Pharmacokinetics, Safety, and Preliminary Efficacy of Topical AhR Agonist Tapinarof: Results of a Phase 1 Study.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 524, doi. 10.1002/cpdd.439

By:

Bissonnette, Robert;
Vasist, Lakshmi S.;
Bullman, Jonathan N.;
Collingwood, Therese;
Chen, Geng;
Maeda‐Chubachi, Tomoko

Publication type:

Article

Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 506, doi. 10.1002/cpdd.431

By:

Rasmussen, Scott;
Horkan, Kathleen Halabuk;
Kotler, Mitchell

Publication type:

Article

Phase 1b Trial of Ficlatuzumab, a Humanized Hepatocyte Growth Factor Inhibitory Monoclonal Antibody, in Combination With Gefitinib in Asian Patients With NSCLC.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 532, doi. 10.1002/cpdd.427

By:

Tan, Eng‐Huat;
Lim, Wan‐Teck;
Ahn, Myung‐Ju;
Ng, Quan‐Sing;
Ahn, Jin Seok;
Shao‐Weng Tan, Daniel;
Sun, Jong‐Mu;
Han, May;
Payumo, Francis C.;
McKee, Krista;
Yin, Wei;
Credi, Marc;
Agarwal, Shefali;
Jac, Jaroslaw;
Park, Keunchil

Publication type:

Article

A Phase 1, Randomized, Placebo‐ and Active‐Controlled Crossover Study to Determine the Effect of Single‐Dose Ertugliflozin on QTc Interval in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 513, doi. 10.1002/cpdd.421

By:

Sahasrabudhe, Vaishali;
Saur, Didier;
Matschke, Kyle;
Terra, Steven G.;
Hickman, Anne;
Huyghe, Isabelle;
Shi, Haihong;
Cutler, David L.

Publication type:

Article

To Take or Not to Take With Meals? Unraveling Issues Related to Food Effects Labeling for Oral Antineoplastic Drugs.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 455, doi. 10.1002/cpdd.416

By:

Deng, Jiexin;
Brar, Satjit S.;
Lesko, Lawrence J.

Publication type:

Article

Single‐Dose Bioequivalence of Two Mini Nicotine Lozenge Formulations.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 498, doi. 10.1002/cpdd.415

By:

Rasmussen, Scott C.;
Becker, William D.;
Shanga, Gilbert M.

Publication type:

Article

Pharmacokinetics, Pharmacodynamics, and Safety of a Long‐Acting Human Growth Hormone (MOD‐4023) in Healthy Japanese and Caucasian Adults.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 554, doi. 10.1002/cpdd.414

By:

Kramer, William G.;
Jaron‐Mendelson, Michal;
Koren, Ronit;
Hershkovitz, Oren;
Hart, Gili

Publication type:

Article

Two Phase 1, Open‐Label, Single‐Dose, Randomized, Crossover Studies to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered Granules of Secnidazole (2 g) in Healthy Female Volunteers Under Different Administration Conditions

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 543, doi. 10.1002/cpdd.406

By:

Pentikis, Helen S.;
Adetoro, Nikki

Publication type:

Article